Work with academic experts in cell biology

A scholar or researcher with expertise in cell biology can help business and industrial clients solve their cell biology problems and conduct cell biology research to get ahead on R&D. Experts on NotedSource with backgrounds in cell biology include Aimee Eggler, Elizabeth Kish, Krista Kaasik, Giuliana Noratto, Ammon Posey, Oleh Khalimonchuk, Jeffrey Townsend, Diane Imburgio, Diane Imburgio, Edoardo Airoldi, Peter Reich, Boris Leibovitch, Lee Weinstein, Michael W Harman, Dr. Susanne Ressl, Katelyn Katelyn Masiuk, and John Joe.

Aimee Eggler

Professor of Chemistry and Biochemistry at Villanova University
Villanova, Pennsylvania, United States of America
Most Relevant Research Interests
Cell Biology
Other Research Interests (26)
Biochemistry
Biochemistry education
Cell culture
Oxidative stress
Natural products
And 21 more
About
Most Relevant Publications (6+)

25 total publications

Screening for natural chemoprevention agents that modify human Keap1

Analytical Biochemistry / Feb 01, 2012

Hu, C., Nikolic, D., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2012). Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry, 421(1), 108–114. https://doi.org/10.1016/j.ab.2011.10.028

Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1

Biochemical and Biophysical Research Communications / Oct 01, 2010

Small, E., Eggler, A., & Mesecar, A. D. (2010). Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1. Biochemical and Biophysical Research Communications, 400(4), 471–475. https://doi.org/10.1016/j.bbrc.2010.08.062

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1

Biochemical Journal / Jul 29, 2009

Eggler, A. L., Small, E., Hannink, M., & Mesecar, A. D. (2009). Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. Biochemical Journal, 422(1), 171–180. https://doi.org/10.1042/bj20090471

The C Terminus of the Escherichia coli RecA Protein Modulates the DNA Binding Competition with Single-stranded DNA-binding Protein

Journal of Biological Chemistry / May 01, 2003

Eggler, A. L., Lusetti, S. L., & Cox, M. M. (2003). The C Terminus of the Escherichia coli RecA Protein Modulates the DNA Binding Competition with Single-stranded DNA-binding Protein. Journal of Biological Chemistry, 278(18), 16389–16396. https://doi.org/10.1074/jbc.m212920200

The Rad51-dependent Pairing of Long DNA Substrates Is Stabilized by Replication Protein A

Journal of Biological Chemistry / Oct 01, 2002

Eggler, A. L., Inman, R. B., & Cox, M. M. (2002). The Rad51-dependent Pairing of Long DNA Substrates Is Stabilized by Replication Protein A. Journal of Biological Chemistry, 277(42), 39280–39288. https://doi.org/10.1074/jbc.m204328200

DNA Pairing and Strand Exchange by the Escherichia coli RecA and Yeast Rad51 Proteins without ATP Hydrolysis

Journal of Biological Chemistry / Oct 01, 2001

Rice, K. P., Eggler, A. L., Sung, P., & Cox, M. M. (2001). DNA Pairing and Strand Exchange by the Escherichia coli RecA and Yeast Rad51 Proteins without ATP Hydrolysis. Journal of Biological Chemistry, 276(42), 38570–38581. https://doi.org/10.1074/jbc.m105678200

Elizabeth Kish

I'm Liz and I'm currently a post doc at Columbia University. I also consult for a start up that is based in France and do technology evaluations for investors looking at biotech.
Most Relevant Research Interests
cell biology
Other Research Interests (11)
biophysics
nuclear magnetic resonance
raman spectroscopy
technology evaluation
spectroscopy
And 6 more
About
Most Relevant Publications (2+)

4 total publications

Twisting a β-Carotene, an Adaptive Trick from Nature for Dissipating Energy during Photoprotection

Journal of Biological Chemistry / Jan 01, 2017

Llansola-Portoles, M. J., Sobotka, R., Kish, E., Shukla, M. K., Pascal, A. A., Polívka, T., & Robert, B. (2017). Twisting a β-Carotene, an Adaptive Trick from Nature for Dissipating Energy during Photoprotection. Journal of Biological Chemistry, 292(4), 1396–1403. https://doi.org/10.1074/jbc.m116.753723

Probing the pigment binding sites in LHCII with resonance Raman spectroscopy: The effect of mutations at S123

Biochimica et Biophysica Acta (BBA) - Bioenergetics / Sep 01, 2016

Kish, E., Wang, K., Llansola-Portoles, M. J., Ilioaia, C., Pascal, A. A., Robert, B., & Yang, C. (2016). Probing the pigment binding sites in LHCII with resonance Raman spectroscopy: The effect of mutations at S123. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1857(9), 1490–1496. https://doi.org/10.1016/j.bbabio.2016.06.001

Giuliana Noratto

Food Scientist PhD and Registered Dietician - Texas A&M University
Most Relevant Research Interests
Cell Biology
Other Research Interests (49)
Food Science
human nutrition
disease prevention and treatment
Nutrition
Human Health
And 44 more
About
Most Relevant Publications (1+)

91 total publications

The role of dietary polyphenols in osteosarcoma: A possible clue about the molecular mechanisms involved in a process that is just in its infancy

Journal of Food Biochemistry / Dec 07, 2021

Rabelo, A. C. S., Borghesi, J., & Noratto, G. D. (2021). The role of dietary polyphenols in osteosarcoma: A possible clue about the molecular mechanisms involved in a process that is just in its infancy. Journal of Food Biochemistry, 46(1). Portico. https://doi.org/10.1111/jfbc.14026

Ammon Posey

Research Scientist, Washington University in St. Louis
Most Relevant Research Interests
Cell Biology
Cell Biology
Cell Biology
Other Research Interests (24)
Experimental Biophysics
Data Analysis
intrinsically disordered proteins
protein aggregation
phase transitions
And 19 more
About
Most Relevant Publications (5+)

49 total publications

A Lethal de Novo Mutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division

Journal of Biological Chemistry / Oct 01, 2010

Chang, C.-R., Manlandro, C. M., Arnoult, D., Stadler, J., Posey, A. E., Hill, R. B., & Blackstone, C. (2010). A Lethal de Novo Mutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division. Journal of Biological Chemistry, 285(42), 32494–32503. https://doi.org/10.1074/jbc.m110.142430

Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation

Molecular Cell / Mar 01, 2020

Greig, J. A., Nguyen, T. A., Lee, M., Holehouse, A. S., Posey, A. E., Pappu, R. V., & Jedd, G. (2020). Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation. Molecular Cell, 77(6), 1237-1250.e4. https://doi.org/10.1016/j.molcel.2020.01.025

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers

Journal of Biological Chemistry / Mar 01, 2018

Posey, A. E., Ruff, K. M., Harmon, T. S., Crick, S. L., Li, A., Diamond, M. I., & Pappu, R. V. (2018). Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers. Journal of Biological Chemistry, 293(10), 3734–3746. https://doi.org/10.1074/jbc.ra117.000357

A Targeted Mutation Identified through pK Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission

Journal of Biological Chemistry / Sep 01, 2016

Koppenol-Raab, M., Harwig, M. C., Posey, A. E., Egner, J. M., MacKenzie, K. R., & Hill, R. B. (2016). A Targeted Mutation Identified through pK Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission. Journal of Biological Chemistry, 291(39), 20329–20344. https://doi.org/10.1074/jbc.m116.724005

A First Glimpse of Nucleation of Phase Transitions in Living Cells

Molecular Cell / Jul 01, 2018

Posey, A. E., & Pappu, R. V. (2018). A First Glimpse of Nucleation of Phase Transitions in Living Cells. Molecular Cell, 71(1), 1–3. https://doi.org/10.1016/j.molcel.2018.06.028

Jeffrey Townsend

Professor of Biostatistics and Ecology & Evolutionary Biology
New Haven, CT
Most Relevant Research Interests
Cell Biology
Other Research Interests (78)
Statistics
cancer genetics
disease modeling
antibiotic resistance
Evolutionary Genomics
And 73 more
About
Most Relevant Publications (3+)

207 total publications

Phylogenetic and phylogenomic overview of the Polyporales

Mycologia / Nov 01, 2013

Binder, M., Justo, A., Riley, R., Salamov, A., Lopez-Giraldez, F., Sjökvist, E., Copeland, A., Foster, B., Sun, H., Larsson, E., Larsson, K.-H., Townsend, J., Grigoriev, I. V., & Hibbett, D. S. (2013). Phylogenetic and phylogenomic overview of the Polyporales. Mycologia, 105(6), 1350–1373. https://doi.org/10.3852/13-003

Modelling microbial infection to address global health challenges

Nature Microbiology / Sep 20, 2019

Fitzpatrick, M. C., Bauch, C. T., Townsend, J. P., & Galvani, A. P. (2019). Modelling microbial infection to address global health challenges. Nature Microbiology, 4(10), 1612–1619. https://doi.org/10.1038/s41564-019-0565-8

Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny

Mycologia / Sep 01, 2010

Ohenoja, E., Wang, Z., Townsend, J. P., Mitchel, D., & Voitk, A. (2010). Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny. Mycologia, 102(5), 1089–1095. https://doi.org/10.3852/09-317

Edoardo Airoldi

Professor of Statistics & Data Science Temple University & PI, Harvard University
Most Relevant Research Interests
Cell Biology
Other Research Interests (63)
Statistics
Causal Inference
Network Science
Statistical Machine Learning
Computational Biology
And 58 more
About
Most Relevant Publications (6+)

106 total publications

Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy

Autophagy / Aug 22, 2014

Klionsky, D. J. (2014). Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 10(10), 1691–1691. https://doi.org/10.4161/auto.36187

Analysis and design of RNA sequencing experiments for identifying isoform regulation

Nature Methods / Nov 07, 2010

Katz, Y., Wang, E. T., Airoldi, E. M., & Burge, C. B. (2010). Analysis and design of RNA sequencing experiments for identifying isoform regulation. Nature Methods, 7(12), 1009–1015. https://doi.org/10.1038/nmeth.1528

Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast

Molecular Biology of the Cell / Jan 01, 2008

Brauer, M. J., Huttenhower, C., Airoldi, E. M., Rosenstein, R., Matese, J. C., Gresham, D., Boer, V. M., Troyanskaya, O. G., & Botstein, D. (2008). Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast. Molecular Biology of the Cell, 19(1), 352–367. https://doi.org/10.1091/mbc.e07-08-0779

Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis

Molecular Cell / Jul 01, 2016

Solís, E. J., Pandey, J. P., Zheng, X., Jin, D. X., Gupta, P. B., Airoldi, E. M., Pincus, D., & Denic, V. (2016). Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis. Molecular Cell, 63(1), 60–71. https://doi.org/10.1016/j.molcel.2016.05.014

A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes

Molecular Biology of the Cell / May 15, 2012

Slavov, N., Airoldi, E. M., van Oudenaarden, A., & Botstein, D. (2012). A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes. Molecular Biology of the Cell, 23(10), 1986–1997. https://doi.org/10.1091/mbc.e11-11-0961

Steady-state and dynamic gene expression programs inSaccharomyces cerevisiaein response to variation in environmental nitrogen

Molecular Biology of the Cell / Apr 15, 2016

Airoldi, E. M., Miller, D., Athanasiadou, R., Brandt, N., Abdul-Rahman, F., Neymotin, B., Hashimoto, T., Bahmani, T., & Gresham, D. (2016). Steady-state and dynamic gene expression programs inSaccharomyces cerevisiaein response to variation in environmental nitrogen. Molecular Biology of the Cell, 27(8), 1383–1396. https://doi.org/10.1091/mbc.e14-05-1013

Peter Reich

Director of the Institute for Global Change Biology (IGCB)
Most Relevant Research Interests
Cell Biology
Other Research Interests (44)
Multidisciplinary
General Earth and Planetary Sciences
Ecology
Ecology, Evolution, Behavior and Systematics
General Environmental Science
And 39 more
About
Most Relevant Publications (5+)

509 total publications

Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities

Mycologia / Jul 01, 2009

Dickie, I. A., Dentinger, B. T. M., Avis, P. G., McLaughlin, D. J., & Reich, P. B. (2009). Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities. Mycologia, 101(4), 473–483. https://doi.org/10.3852/08-178

Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen

Physiologia Plantarum / Aug 01, 1996

Volin, J. C., & Reich, P. B. (1996). Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen. Physiologia Plantarum, 97(4), 674–684. https://doi.org/10.1034/j.1399-3054.1996.970407.x

Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings

Physiologia Plantarum / Dec 01, 1993

Kruger, E. L., & Reich, P. B. (1993). Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings. Physiologia Plantarum, 89(4), 751–760. https://doi.org/10.1111/j.1399-3054.1993.tb05281.x

Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean

Physiologia Plantarum / Jan 01, 1985

Reich, P. B., Schoettle, A. W., & Amundson, R. G. (1985). Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean. Physiologia Plantarum, 63(1), 58–64. https://doi.org/10.1111/j.1399-3054.1985.tb02818.x

Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark

Physiologia Plantarum / Aug 01, 1984

Reich, P. B. (1984). Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark. Physiologia Plantarum, 61(4), 541–548. https://doi.org/10.1111/j.1399-3054.1984.tb05167.x

Boris Leibovitch

Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
New York, New York, United States of America
Most Relevant Research Interests
Cell Biology
Other Research Interests (11)
Cancer Research
Developmental Biology
Molecular Biology
Multidisciplinary
Hematology
And 6 more
About
Most Relevant Publications (3+)

22 total publications

Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors

Developmental Biology / Jan 01, 2011

Marzan, C. V., Kupumbati, T. S., Bertran, S. P., Samuels, T., Leibovitch, B., Mira-y-Lopez, R., Ossowski, L., & Farias, E. F. (2011). Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors. Developmental Biology, 349(2), 125–136. https://doi.org/10.1016/j.ydbio.2010.10.018

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

Blood / Mar 15, 2008

Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122

GAGA Factor and the TFIID Complex Collaborate in Generating an Open Chromatin Structure at the Drosophila melanogaster hsp26 Promoter

Molecular and Cellular Biology / Sep 01, 2002

Leibovitch, B. A., Lu, Q., Benjamin, L. R., Liu, Y., Gilmour, D. S., & Elgin, S. C. R. (2002). GAGA Factor and the TFIID Complex Collaborate in Generating an Open Chromatin Structure at the Drosophila melanogaster hsp26 Promoter. Molecular and Cellular Biology, 22(17), 6148–6157. https://doi.org/10.1128/mcb.22.17.6148-6157.2002

Lee Weinstein

STEM Educator
Most Relevant Research Interests
Cell Biology
Other Research Interests (34)
Energy conversion
solar energy
thermoelectrics
General Chemistry
Energy Engineering and Power Technology
And 29 more
About
Most Relevant Publications (1+)

22 total publications

Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin

Apoptosis / May 21, 2008

Bakhshi, J., Weinstein, L., Poksay, K. S., Nishinaga, B., Bredesen, D. E., & Rao, R. V. (2008). Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin. Apoptosis, 13(7), 904–914. https://doi.org/10.1007/s10495-008-0221-x

Dr. Susanne Ressl

Biochemist & Structural Biologist | Project & Team Leader | Creative & Translational Thinker | Problem Solver | Mentor | Educator | Consultant | Innovator | Science Communicator & Writer | Relationship Builder | Collaborator
Most Relevant Research Interests
Cell Biology
Other Research Interests (44)
Structural Neuroscience of Synapse Organizing Molecules
Multidisciplinary
General Neuroscience
Virology
Microbiology
And 39 more
Most Relevant Publications (2+)

20 total publications

Munc18a Does Not Alter Fusion Rates Mediated by Neuronal SNAREs, Synaptotagmin, and Complexin

Journal of Biological Chemistry / Apr 01, 2015

Zhang, Y., Diao, J., Colbert, K. N., Lai, Y., Pfuetzner, R. A., Padolina, M. S., Vivona, S., Ressl, S., Cipriano, D. J., Choi, U. B., Shah, N., Weis, W. I., & Brunger, A. T. (2015). Munc18a Does Not Alter Fusion Rates Mediated by Neuronal SNAREs, Synaptotagmin, and Complexin. Journal of Biological Chemistry, 290(16), 10518–10534. https://doi.org/10.1074/jbc.m114.630772

K+-induced conformational changes in the trimeric betaine transporter BetP monitored by ATR-FTIR spectroscopy

Biochimica et Biophysica Acta (BBA) - Biomembranes / Apr 01, 2013

Korkmaz, F., Ressl, S., Ziegler, C., & Mäntele, W. (2013). K+-induced conformational changes in the trimeric betaine transporter BetP monitored by ATR-FTIR spectroscopy. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1828(4), 1181–1191. https://doi.org/10.1016/j.bbamem.2013.01.004

Katelyn Katelyn Masiuk

Co-Founder and CSO at Immunovec
Most Relevant Research Interests
Cell Biology
Other Research Interests (26)
Genetics
Molecular Medicine
Genetics
Molecular Biology
Molecular Medicine
And 21 more
About
Most Relevant Publications (4+)

13 total publications

Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome

Cell Stem Cell / Feb 01, 2019

Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003

Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy

Stem Cells / Apr 23, 2015

Baldwin, K., Urbinati, F., Romero, Z., Campo-Fernandez, B., Kaufman, M. L., Cooper, A. R., Masiuk, K., Hollis, R. P., & Kohn, D. B. (2015). Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy. Stem Cells, 33(5), 1532–1542. https://doi.org/10.1002/stem.1957

Lentiviral gene therapy for X-linked chronic granulomatous disease recapitulates endogenousCYBBregulation and expression

Blood / Mar 02, 2023

Wong, R. L., Sackey, S., Brown, D., Senadheera, S., Masiuk, K., Quintos, J. P., Colindres, N., Riggan, L., Morgan, R. A., Malech, H. L., Hollis, R. P., & Kohn, D. B. (2023). Lentiviral gene therapy for X-linked chronic granulomatous disease recapitulates endogenousCYBBregulation and expression. Blood, 141(9), 1007–1022. https://doi.org/10.1182/blood.2022016074

Enrichment of Hematopoietic Stem Cells Using Immunomagnetic Beads to Facilitate Gene Therapy

Blood / Dec 02, 2016

Masiuk, K. E., Brown, D., Urbinati, F., Hollis, R. P., & Kohn, D. B. (2016). Enrichment of Hematopoietic Stem Cells Using Immunomagnetic Beads to Facilitate Gene Therapy. Blood, 128(22), 2313–2313. https://doi.org/10.1182/blood.v128.22.2313.2313

John Joe

Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Most Relevant Research Interests
Cell Biology
Other Research Interests (73)
microbiology
systems biology
genetics
quantum biology
Genetics
And 68 more
Most Relevant Publications (2+)

95 total publications

Genus- and species-specific DNA probes to identify mycobacteria using the polymerase chain reaction

Molecular and Cellular Probes / Apr 01, 1990

Fries, J. W. U., Patel, R. J., Piessens, W. F., & Wirth, D. F. (1990). Genus- and species-specific DNA probes to identify mycobacteria using the polymerase chain reaction. Molecular and Cellular Probes, 4(2), 87–105. https://doi.org/10.1016/0890-8508(90)90011-n

The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

Journal of Biological Chemistry / Apr 01, 2018

Basu, P., Sandhu, N., Bhatt, A., Singh, A., Balhana, R., Gobe, I., Crowhurst, N. A., Mendum, T. A., Gao, L., Ward, J. L., Beale, M. H., McFadden, J., & Beste, D. J. V. (2018). The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis. Journal of Biological Chemistry, 293(15), 5695–5704. https://doi.org/10.1074/jbc.ra118.001839