Work with thought leaders and academic experts in gastroenterology

Companies can greatly benefit from collaborating with academic researchers in the field of Gastroenterology. These experts can provide valuable insights, research, and expertise to enhance various aspects of a company's operations. Here are some ways companies can collaborate with Gastroenterology researchers:

Researchers on NotedSource with backgrounds in gastroenterology include Dr. Everson A Nunes, Ph.D., Dr. Shilpa Patil, Ph.D, Giuliana Noratto, Luke Connelly, Gwendolyn Thomas, Ph.D., Roshonda Jones, Carissa Pardamean, PhD, Dr. Abbas Poorhashemi, Leo R Fitzpatrick PhD, Marina Baretti, Kayvan Najarian, Shenazar Esmundo, and Jonathan Moore.

Dr. Everson A Nunes, Ph.D.

Hamilton, Ontario, Canada
Post-Doctoral Fellow at McMaster University | former Associate Professor - Physiological Sciences
Most Relevant Research Interests
Gastroenterology
Other Research Interests (39)
skeletal muscle
nutrition
physical activity
obesity
cancer
And 34 more
About
Dr. Everson A Nunes is a highly accomplished researcher and educator in the field of physiological sciences. He received his Ph.D. in Cellular and Molecular Biology with a focus on Physiological Sciences from Universidade Federal do Paraná in 2009, after completing a BSc in Human Nutrition and an MSc in Physiological Sciences. He also holds a specialization in Exercise Physiology and a BSc in Biological Sciences from Universidade Federal do Paraná. Dr. Nunes has a strong background in research, having completed two post-doctoral fellowships at McMaster University and Universidade Federal do Paraná. He has also held positions as an associate professor and assistant professor at Universidade Federal de Santa Catarina. He has published numerous articles in peer-reviewed journals, and his research focuses on the effects of exercise and nutrition on physiological processes in the human body. In addition to his research, Dr. Nunes is also a dedicated educator. He has taught at various universities in Brazil, including Universidade Federal de Santa Catarina, Universidade Gama Filho, Faculdades Integradas Espírita, Pontificia Universidade Católica do Paraná, and Faculdade do Litoral Sul. He is known for his dynamic teaching style and his ability to engage students in complex physiological concepts. Dr. Nunes is a member of several professional organizations, including the American Society for Nutrition, the Canadian Society of Exercise Physiology, the Canadian Nutrition Society and the Brazilian Society of Physiology. He is also a regular speaker at national and international conferences, sharing his expertise and research findings with colleagues and students. Overall, Dr. Nunes is a highly qualified and experienced professional in physiological sciences, metabolism, cancer and nutrition. His dedication to research and education makes him a valuable asset to any institution.
Most Relevant Publications (1+)

97 total publications

Effects of Prebiotic and Synbiotic Supplementation on Inflammatory Markers and Anthropometric Indices After Roux-en-Y Gastric Bypass

Journal of Clinical Gastroenterology / Mar 01, 2016

Fernandes, R., Beserra, B. T. S., Mocellin, M. C., Kuntz, M. G. F., da Rosa, J. S., de Miranda, R. C. D., Schreiber, C. S. O., Fröde, T. S., Nunes, E. A., & Trindade, E. B. S. M. (2016). Effects of Prebiotic and Synbiotic Supplementation on Inflammatory Markers and Anthropometric Indices After Roux-en-Y Gastric Bypass: A Randomized, Triple-blind, Placebo-controlled Pilot Study. Journal of Clinical Gastroenterology, 50(3), 208–217. https://doi.org/10.1097/mcg.0000000000000328

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Dr. Shilpa Patil, Ph.D

Vancouver, British Columbia, Canada
PhD & Postdoc level expertise in Cancer Research
Most Relevant Research Interests
Gastroenterology
Other Research Interests (11)
Cancer
epigenetics
development
Oncology
Cancer Research
And 6 more
About
Dr. Shilpa Patil is a highly experienced cancer researcher with a strong background in Preclinical studies. She received her Ph.D. in Molecular Medicine from the University of Göttingen in 2020, where she focused on developing novel treatments for pancreatic cancer. Prior to that, she completed her MSc in Regenerative Medicine from Manipal University in 2014 and her BSc in Biotechnology from the same institution in 2012. With over 6 years of research experience, Dr. Patil has worked at prestigious institutions such as the University of British Columbia, University of Göttingen and JNCASR. Her expertise lies in the areas of cancer biology, epigenetics, cell and molecular biology, and regenerative medicine. She has published numerous research articles in reputed journals and has presented her work at various international conferences. Dr. Patil is a dedicated and passionate scientist, committed to using her knowledge and skills to contribute to the fight against cancer. She is driven by her curiosity to unravel complex biological processes and her desire to make a positive impact in the field of cancer research. She is also driven to bridge the academia-industry gap.
Most Relevant Publications (5+)

20 total publications

Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes

Visceral Medicine / Dec 27, 2021

Patil, S., Dou, Y., & Kopp, J. L. (2021). Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes. Visceral Medicine, 38(1), 4–10. Portico. https://doi.org/10.1159/000520946

NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming

Cellular and Molecular Gastroenterology and Hepatology / Jan 01, 2023

Zhang, Z., Wang, X., Hamdan, F. H., Likhobabina, A., Patil, S., Aperdannier, L., Sen, M., Traub, J., Neesse, A., Fischer, A., Papantonis, A., Singh, S. K., Ellenrieder, V., Johnsen, S. A., & Hessmann, E. (2023). NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming. Cellular and Molecular Gastroenterology and Hepatology, 15(5), 1219–1246. https://doi.org/10.1016/j.jcmgh.2023.01.015

EZH2 controls PDAC plasticity by regulating differentiation genes

Pancreatology / Jun 01, 2019

Patil, S., Najafova, Z., Kari, V., Wang, X., Bohnenberger, H., Kopp, W., Spitalieri, J., Neesse, A., Ellenrieder, V., Johnsen, S., & Hessmann, E. (2019). EZH2 controls PDAC plasticity by regulating differentiation genes. Pancreatology, 19, S11. https://doi.org/10.1016/j.pan.2019.05.021

Impact of cytosolic 5'-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer

Pancreatology / Jun 01, 2018

Patzak, M. S., Hessmann, E., Kari, V., Kitz, J., Patil, S., Richards, F. M., Jodrell, D. I., Johnsen, S. A., Ellenrieder, V., & Neesse, A. (2018). Impact of cytosolic 5’-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer. Pancreatology, 18(4), S91. https://doi.org/10.1016/j.pan.2018.05.247

Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity

Pancreatology / Jul 01, 2017

Patil, S., Witte, H., Neesse, A., Johnsen, S., Ellenrieder, V., & Hessmann, E. (2017). Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity. Pancreatology, 17(3), S41. https://doi.org/10.1016/j.pan.2017.05.128

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Luke Connelly

Professor of Health Economics, The University of Queensland, CBEH
Most Relevant Research Interests
Gastroenterology
Other Research Interests (42)
Health economics
insurance
Public Health, Environmental and Occupational Health
Safety, Risk, Reliability and Quality
Human Factors and Ergonomics
And 37 more
About
Luke Connelly is Professor of Health Economics at the Centre for the Business and Economics of Health. He also holds a Professorial appointment (part-time) at The University of Bologna, to which he was appointed in 2017 via the Italian “Direct Call” ([link](https://www.unibo.it/sitoweb/luke.connelly/en)) process. In 2019 he was appointed as Honorary Professor at The University of Sydney. His main interests are in health economics and insurance economics and the effects of institutions (including legal constructs) on incentives and behaviour. He has also worked in other fields of applied microeconomics, including education economics and transport economics. His publications include papers in *Review of Income and Wealth*, *Health Economics*, *Journal of Health Economics*, *Journal of Risk and Insurance*, *Geneva Papers on Risk and Insurance*, *Accident Analysis and Prevention*, *Journal of Law and Medicine*, *Journal of Clinical Epidemiology*, *European Journal of Health Economics*, *International Journal of Health Economics and Finance*, *Social Science and Medicine*, *Economic Papers*, *Economic Analysis and Policy*, *Journal of Transport Economics and Policy*, *Labour Economics*, *Economics and Human Biology* as well as in a range of clinical journals, including *Lancet*. Luke has served on a number of public committees including the Medical Services Advisory Committee (MSAC), which advises the Australian Minister for Health on the safety, efficacy, effectiveness, and cost-effectiveness of new and extant listings on Australia's Medicare Benefits Schedule. He has extensive service on other public committees and taskforces as well as extensive teaching and consulting engagements with industry. Over his career he has been a chief investigator on research grants and contracts totalling more than $67m. He is a member of the Editorial Boards of European Journal of Health Economics and the International Journal on Environmental Research and Public Health. He is a member of the International Health Economics Association's Arrow Awards Committee, which awards an annual prize in honour of Nobel Laureate Kenneth Arrow for the best paper in the field. He is currently Guest Editor (with Christophe Courbage) on a Special Issue of the Geneva Papers on Risk and Insurance on Insurance and Emerging Health Risks. His current research interests include health service innovations to improve the health of people with chronic kidney disease(CKD). Ongoing interests include the economics of disability and insurance, compensable injury compensation schemes, and the determinants of health. Luke enjoys and has considerable experience teaching economics and health economics at both the graduate and undergraduate levels. In 2014 he was awarded the School of Economics Distinguished Teaching Award for his teaching on UQ's Master of Health Economics Program. In July 2016 and July 2019 he also taught summer schools in Health Economics and the Economics of Insurance at The University of Lucerne, Switzerland. Over the past 10 years he has been a chief investigator on grants totalling more than $70m.
Most Relevant Publications (1+)

105 total publications

Economic evaluation of fecal microbiota transplantation for the treatment of recurrentClostridium difficileinfection in Australia

Journal of Gastroenterology and Hepatology / Nov 29, 2016

Merlo, G., Graves, N., Brain, D., & Connelly, L. B. (2016). Economic evaluation of fecal microbiota transplantation for the treatment of recurrentClostridium difficileinfection in Australia. Journal of Gastroenterology and Hepatology, 31(12), 1927–1932. Portico. https://doi.org/10.1111/jgh.13402

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Gwendolyn Thomas, Ph.D.

Degreed Exercise Physiologist (PhD) with 15+ years experience in clinical research in oncology, obesity and chronic disease. Strong investigative and analytical skills that fostered relationships with expert faculty and collaborators across department, division and institution, as well as within industry, foundations and government to develop Clinical Trial Protocols, scientific publications, and presentations.
Most Relevant Research Interests
Gastroenterology
Other Research Interests (27)
resistance exercise
obesity
breast cancer
chronic disease
inflammation
And 22 more
About
Strong training and experience in clinical research regulatory requirements as both Principal Investigator and Internal Review Board member.Strong analytical skills with the ability to interpret clinical trial data and synthesize conclusions. Facilitates interactions between key stakeholders across department, division, institution and industry and government partners using a proactive approach, strategic thinking and leadership to accomplish study goals and timelines. Ability to manage multiple competing priorities with good planning, time management and prioritization skills. Project milestones met through problem solving, prioritization, conflict resolution and critical thinking skills. Advanced communication, scientific writing and presentation skills at both university and national/international stakeholder conferences. As Principal Investigator responsibilities include completing high quality literature reviews of clinical trials, peer-reviewed articles, clinical guidelines and other medical data sources to allow for oversight of project deliverables. Extensive experience in independently designing and developing abstracts for peer-reviewed publications, scientific posters and podium presentations at both national and international conferences.
Most Relevant Publications (1+)

47 total publications

Implementation of a Postoperative Screening and Treatment Guidance for the Low Anterior Resection Syndrome: Preliminary Results

Diseases of the Colon & Rectum / Sep 01, 2019

van der Heijden, J. A. G., van Heinsbergen, M., Thomas, G., Caers, F., Slooter, G. D., & Maaskant-Braat, A. J. G. (2019). Implementation of a Postoperative Screening and Treatment Guidance for the Low Anterior Resection Syndrome: Preliminary Results. Diseases of the Colon & Rectum, 62(9), 1033–1042. https://doi.org/10.1097/dcr.0000000000001428

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Roshonda Jones

Charlotte, North Carolina, United States of America
Bioinformatics research scientist using computational and statistical techniques to examine the relationship between diet, health and microbes
Most Relevant Research Interests
Gastroenterology
Other Research Interests (23)
Bioinfomatics
Microbiome
Childhood Obesity
Microbiology
Microbiology (medical)
And 18 more
About
Roshonda Jones is an experienced bioinformatics and computational biologist with a passion for exploring the complexities of life. She earned her Ph.D. in Bioinformatics and Computational Biology from University of North Carolina at Charlotte in 2016, and went on to complete a postdoctoral fellowship at USC, as well as a postdoctoral research fellowship at Children’s Hospital Los Angeles. Her research interests include machine learning and bioinformatics. She is committed to using her expertise to further scientific knowledge and advance the field.
Most Relevant Publications (5+)

43 total publications

Mouse Paneth cell antimicrobial function is independent of Nod2

Gut / Mar 19, 2013

Shanahan, M. T., Carroll, I. M., Grossniklaus, E., White, A., von Furstenberg, R. J., Barner, R., Fodor, A. A., Henning, S. J., Sartor, R. B., & Gulati, A. S. (2013). Mouse Paneth cell antimicrobial function is independent of Nod2. Gut, 63(6), 903–910. https://doi.org/10.1136/gutjnl-2012-304190

High intake of dietary fructose in overweight/obese teenagers associated with depletion of Eubacterium and Streptococcus in gut microbiome

Gut Microbes / Apr 16, 2019

Jones, R. B., Alderete, T. L., Kim, J. S., Millstein, J., Gilliland, F. D., & Goran, M. I. (2019). High intake of dietary fructose in overweight/obese teenagers associated with depletion of Eubacterium and Streptococcus in gut microbiome. Gut Microbes, 10(6), 712–719. https://doi.org/10.1080/19490976.2019.1592420

Early life gut microbiota is associated with rapid infant growth in Hispanics from Southern California

Gut Microbes / Jan 01, 2021

Alderete, T. L., Jones, R. B., Shaffer, J. P., Holzhausen, E. A., Patterson, W. B., Kazemian, E., Chatzi, L., Knight, R., Plows, J. F., Berger, P. K., & Goran, M. I. (2021). Early life gut microbiota is associated with rapid infant growth in Hispanics from Southern California. Gut Microbes, 13(1). https://doi.org/10.1080/19490976.2021.1961203

Lactose-reduced infant formula with added corn syrup solids is associated with a distinct gut microbiota in Hispanic infants

Gut Microbes / Sep 04, 2020

Jones, R. B., Berger, P. K., Plows, J. F., Alderete, T. L., Millstein, J., Fogel, J., Iablokov, S. N., Rodionov, D. A., Osterman, A. L., Bode, L., & Goran, M. I. (2020). Lactose-reduced infant formula with added corn syrup solids is associated with a distinct gut microbiota in Hispanic infants. Gut Microbes, 12(1), 1813534. https://doi.org/10.1080/19490976.2020.1813534

Sa1801 Local Environmental Conditions Override NOD2-Mediated Regulatory Effects on Mouse Intestinal Microbial Composition

Gastroenterology / May 01, 2013

Carroll, I. M., Shanahan, M. T., Barner, R., Fodor, A. A., Sartor, R. B., & Gulati, A. S. (2013). Sa1801 Local Environmental Conditions Override NOD2-Mediated Regulatory Effects on Mouse Intestinal Microbial Composition. Gastroenterology, 144(5), S-309. https://doi.org/10.1016/s0016-5085(13)61112-9

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Carissa Pardamean, PhD

Cambridge, Massachusetts, United States of America
Scientific writer and linguist with a wide variety of experiences, including bench science and data analytics. Have worked in research on smoking cessation and nicotine metabolism, colorectal cancer risk, virology, and RNA biology.
Most Relevant Research Interests
Gastroenterology
Other Research Interests (16)
molecular virology
RNA biology
cellular biology
statistical analysis
scientific writing
And 11 more
About
As a scientific writer and editor, I have had 12+ years experience in scientific writing and editing as the in-house editor, translator, and molecular biology consultant for BioRealm and Bina Nusantara University. I have applied the writing and editing skills during my graduate study years to co-author and edit numerous grants to funding and manuscripts for publications. I have leveraged my training in linguistics to convey information in writing more efficiently and precisely. As a bench scientist, my most recent experiences (6 years) are on RNA biology and virology. I have an overall 10 years experience in molecular and cellular biology techniques. As a linguist, I currently am a lexical linguist, curating the Indonesian language database for Apple. SUMMARY/HIGHLIGHTS Bench science research experience: molecular virology \| RNA biology \| host\-virus interaction \| viral pathogenesis \| gammaherpesvirus \| molecular & cellular biology \| yeast genetics \| OB/GYN oncology Analytical/writing/editing non-bench research experience: nicotine addiction and metabolism \| colorectal cancer risk\, epidemiology\, pathogenesis \| thyroid disorder management \| rice agrogenetics \| linguistics and NPL \| AI/ML application on sciences Some conceptual knowledge (mainly through editing during graduate studies): vaccine candidate platform validation \| immunology \| endosomal recycling pathway Transferable skills: quick learner in new scientific fields and methods \| scientific writing for publications and grants \| basic and clinical studies \| independent project planning \| statistical analysis \| leadership and mentorship
Most Relevant Publications (1+)

8 total publications

Changing colorectal cancer trends in Asians

International Journal of Colorectal Disease / Mar 29, 2016

Pardamean, B., Baurley, J. W., Pardamean, C. I., & Figueiredo, J. C. (2016). Changing colorectal cancer trends in Asians. International Journal of Colorectal Disease, 31(8), 1537–1538. https://doi.org/10.1007/s00384-016-2564-z

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Leo R Fitzpatrick PhD

Greenwood , South Carolina, United States of America
GI Pharmacology and IBD Research Consultant
Most Relevant Research Interests
Gastroenterology
Other Research Interests (32)
Inflammatory Bowel Disease
Colitis
Arthritis
Surgery
Immunology
And 27 more
About
Please see my CV for details. I have 37 years of GI and IBD Research experience. This includes both industry and academic experience.
Most Relevant Publications (47+)

89 total publications

Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase

Digestive Diseases and Sciences / Dec 04, 2007

Maines, L. W., Fitzpatrick, L. R., French, K. J., Zhuang, Y., Xia, Z., Keller, S. N., Upson, J. J., & Smith, C. D. (2007). Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase. Digestive Diseases and Sciences, 53(4), 997–1012. https://doi.org/10.1007/s10620-007-0133-6

Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review

World Journal of Gastroenterology / Jan 01, 2017

Salaritabar, A., Darvishi, B., Hadjiakhoondi, F., Manayi, A., Sureda, A., Nabavi, S. F., Fitzpatrick, L. R., Nabavi, S. M., & Bishayee, A. (2017). Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review. World Journal of Gastroenterology, 23(28), 5097. https://doi.org/10.3748/wjg.v23.i28.5097

CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats

Gastroenterology / Apr 01, 2001

FITZPATRICK, L., WANG, J., & LE, T. (2001). CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats. Gastroenterology, 120(5), A685–A685. https://doi.org/10.1016/s0016-5085(01)83409-0

CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats

Gastroenterology / Apr 01, 2001

Fitzpatrick, L. R., Wang, J., & Le, T. (2001). CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats. Gastroenterology, 120(5), A685. https://doi.org/10.1016/s0016-5085(08)83409-9

4SC-101, a novel immunosuppressive drug, inhibits IL-17 and attenuates colitis in two murine models of inflammatory bowel disease†

Inflammatory Bowel Diseases / Oct 01, 2010

Fitzpatrick, L. R., Deml, L., Hofmann, C., Small, J. S., Groeppel, M., Hamm, S., Lemstra, S., Leban, J., & Ammendola, A. (2010). 4SC-101, a novel immunosuppressive drug, inhibits IL-17 and attenuates colitis in two murine models of inflammatory bowel disease†. Inflammatory Bowel Diseases, 16(10), 1763–1777. https://doi.org/10.1002/ibd.21264

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Digestive Diseases and Sciences / Jan 01, 2000

Fitzpatrick, L. R., Wang, J., & Le, T. (2000). Digestive Diseases and Sciences, 45(12), 2327–2336. https://doi.org/10.1023/a:1005630723111

Effects of the Probiotic Formulation VSL#3 on Colitis in Weanling Rats

Journal of Pediatric Gastroenterology and Nutrition / May 01, 2007

Fitzpatrick, L. R., Hertzog, K. L., Quatse, A. L., Koltun, W. A., Small, J. S., & Vrana, K. (2007). Effects of the Probiotic Formulation VSL#3 on Colitis in Weanling Rats. Journal of Pediatric Gastroenterology and Nutrition, 44(5), 561–570. Portico. https://doi.org/10.1097/mpg.0b013e31803bda51

Dextran Sulfate Sodium-Induced Colitis Is Associated with Enhanced Low Molecular Mass Polypeptide 2 (LMP2) Expression and Is Attenuated in LMP2 Knockout Mice

Digestive Diseases and Sciences / Jul 01, 2006

Fitzpatrick, L. R., Khare, V., Small, J. S., & Koltun, W. A. (2006). Dextran Sulfate Sodium-Induced Colitis Is Associated with Enhanced Low Molecular Mass Polypeptide 2 (LMP2) Expression and Is Attenuated in LMP2 Knockout Mice. Digestive Diseases and Sciences, 51(7), 1269–1276. https://doi.org/10.1007/s10620-006-8047-2

Effect of epidermal growth factor on polyamine-synthesizing enzymes in rat enterocytes

American Journal of Physiology-Gastrointestinal and Liver Physiology / Feb 01, 1987

Fitzpatrick, L. R., Wang, P., & Johnson, L. R. (1987). Effect of epidermal growth factor on polyamine-synthesizing enzymes in rat enterocytes. American Journal of Physiology-Gastrointestinal and Liver Physiology, 252(2), G209–G214. https://doi.org/10.1152/ajpgi.1987.252.2.g209

Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice

Gut Pathogens / Jan 01, 2011

Fitzpatrick, L. R., Small, J. S., Greene, W. H., Karpa, K. D., & Keller, D. (2011). Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice. Gut Pathogens, 3(1), 16. https://doi.org/10.1186/1757-4749-3-16

Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice

Gut Pathogens / Oct 01, 2012

Fitzpatrick, L. R., Small, J. S., Greene, W. H., Karpa, K. D., Farmer, S., & Keller, D. (2012). Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice. Gut Pathogens, 4(1). https://doi.org/10.1186/1757-4749-4-13

Enhanced Intestinal Expression of the Proteasome Subunit Low Molecular Mass Polypeptide 2 in Patients with Inflammatory Bowel Disease

Diseases of the Colon & Rectum / Mar 01, 2007

Fitzpatrick, L. R., Small, J. S., Poritz, L. S., McKenna, K. J., & Koltun, W. A. (2007). Enhanced Intestinal Expression of the Proteasome Subunit Low Molecular Mass Polypeptide 2 in Patients with Inflammatory Bowel Disease. Diseases of the Colon & Rectum, 50(3), 337–350. https://doi.org/10.1007/s10350-006-0796-7

Effect of refeeding on polyamine biosynthesis in isolated enterocytes

American Journal of Physiology-Gastrointestinal and Liver Physiology / May 01, 1986

Fitzpatrick, L. R., Wang, P., Eikenburg, B. E., Haddox, M. K., & Johnson, L. R. (1986). Effect of refeeding on polyamine biosynthesis in isolated enterocytes. American Journal of Physiology-Gastrointestinal and Liver Physiology, 250(5), G709–G713. https://doi.org/10.1152/ajpgi.1986.250.5.g709

A New Model of Chronic Hapten-induced Colitis in Young Rats

Journal of Pediatric Gastroenterology & Nutrition / Mar 01, 2010

Fitzpatrick, L. R., Meirelles, K., Small, J. S., Puleo, F. J., Koltun, W. A., & Cooney, R. N. (2010). A New Model of Chronic Hapten-induced Colitis in Young Rats. Journal of Pediatric Gastroenterology & Nutrition, 50(3), 240–250. https://doi.org/10.1097/mpg.0b013e3181cb8f4a

Relationship between ornithine decarboxylase activity and gastric damage

American Journal of Physiology-Gastrointestinal and Liver Physiology / Dec 01, 1987

Thirumalai, C. H., Tseng, C. C., Tabata, K., Fitzpatrick, L. R., & Johnson, L. R. (1987). Relationship between ornithine decarboxylase activity and gastric damage. American Journal of Physiology-Gastrointestinal and Liver Physiology, 253(1), G1–G6. https://doi.org/10.1152/ajpgi.1987.253.1.g1

Gliotoxin, an Inhibitor of Nuclear Factor-Kappa B, Attenuates Peptidoglycan-Polysaccharide-Induced Colitis in Rats

Inflammatory Bowel Diseases / May 01, 2002

Fitzpatrick, L. R., Wang, J., & Le, T. (2002). Gliotoxin, an Inhibitor of Nuclear Factor-Kappa B, Attenuates Peptidoglycan-Polysaccharide-Induced Colitis in Rats. Inflammatory Bowel Diseases, 8(3), 159–167. https://doi.org/10.1097/00054725-200205000-00001

Acidic Fibroblast Growth Factor Accelerates the Healing of Acetic-Acid-lnduced Gastric Ulcers in Rats

Digestion / Jan 01, 1992

Fitzpatrick, L. R., Jakubowska, A., Martin, G. E., Davis, M., Jaye, M. C., & Dionne, C. A. (1992). Acidic Fibroblast Growth Factor Accelerates the Healing of Acetic-Acid-lnduced Gastric Ulcers in Rats. Digestion, 53(1–2), 17–27. Portico. https://doi.org/10.1159/000200967

T2035 The Novel Probiotic Escherichia coli Strain M-17 Uniquely Inhibits Pro-Inflammatory Cytokine Secretion in Macrophage and Colonic Epithelial Cell Lines

Gastroenterology / May 01, 2010

Fitzpatrick, L. R., Small, J. S., Bostwick, E. F., & Hoerr, R. A. (2010). T2035 The Novel Probiotic Escherichia coli Strain M-17 Uniquely Inhibits Pro-Inflammatory Cytokine Secretion in Macrophage and Colonic Epithelial Cell Lines. Gastroenterology, 138(5), S-618. https://doi.org/10.1016/s0016-5085(10)62848-x

Amiloride inhibits rat mucosal ornithine decarboxylase activity and DNA synthesis

American Journal of Physiology-Gastrointestinal and Liver Physiology / Mar 01, 1988

Ulrich-Baker, M. G., Wang, P., Fitzpatrick, L., & Johnson, L. R. (1988). Amiloride inhibits rat mucosal ornithine decarboxylase activity and DNA synthesis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 254(3), G408–G415. https://doi.org/10.1152/ajpgi.1988.254.3.g408

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Digestive Diseases and Sciences / Jan 01, 2002

Farhadi, A., Keshavarzian, A., Fitzpatrick, L. R., Mutlu, E., Zhang, Y., & Banan, A. (2002). Digestive Diseases and Sciences, 47(6), 1342–1348. https://doi.org/10.1023/a:1015382800434

Indomethacin‐induced gastric antral damage in hamsters: are neutrophils involved?

Alimentary Pharmacology & Therapeutics / Feb 01, 1999

Fitzpatrick, Sakurai, & Le. (1999). Indomethacin‐induced gastric antral damage in hamsters: are neutrophils involved? Alimentary Pharmacology & Therapeutics, 13(2), 195–202. Portico. https://doi.org/10.1046/j.1365-2036.1999.00444.x

Inhibition of IL-17 Release by the Novel Anti-Inflammatory Drug Vidofludimus Involves Attenuation of STAT3 and NF-kappa B Signaling Pathways in Murine Splenocytes and Hapten-Induced Colitis

Gastroenterology / May 01, 2011

Fitzpatrick, L. R., Small, J. S., & Ammendola, A. (2011). Inhibition of IL-17 Release by the Novel Anti-Inflammatory Drug Vidofludimus Involves Attenuation of STAT3 and NF-kappa B Signaling Pathways in Murine Splenocytes and Hapten-Induced Colitis. Gastroenterology, 140(5), S-837. https://doi.org/10.1016/s0016-5085(11)63470-7

Effect of naproxen on the hamster gastric antrum: ulceration, adaptation and efficacy of anti‐ulcer drugs

Alimentary Pharmacology & Therapeutics / Nov 01, 1999

Fitzpatrick, Sakurai, & Le. (1999). Effect of naproxen on the hamster gastric antrum: ulceration, adaptation and efficacy of anti‐ulcer drugs. Alimentary Pharmacology & Therapeutics, 13(11), 1553–1562. Portico. https://doi.org/10.1046/j.1365-2036.1999.00624.x

M1658 A Novel Immunosuppressive Drug (4SC-101) Improves TNBS-Induced Colitis in Mice

Gastroenterology / May 01, 2009

Fitzpatrick, L. R., Small, J. S., Zhang, G., & Jankowsky, R. (2009). M1658 A Novel Immunosuppressive Drug (4SC-101) Improves TNBS-Induced Colitis in Mice. Gastroenterology, 136(5), A-404. https://doi.org/10.1016/s0016-5085(09)61857-6

The modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on OPC antioxidant

The American Journal of Gastroenterology / Sep 01, 2001

FARHADI, A. (2001). The modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on OPC antioxidant. The American Journal of Gastroenterology, 96(9), S290. https://doi.org/10.1016/s0002-9270(01)03699-1

Fos expression in the colonic myenteric plexus induced by water avoidance stress in different rat strains

Gastroenterology / Apr 01, 2001

MIAMPAMBA, M., MILLION, M., & TACHE, Y. (2001). Fos expression in the colonic myenteric plexus induced by water avoidance stress in different rat strains. Gastroenterology, 120(5), A715–A715. https://doi.org/10.1016/s0016-5085(01)83560-5

Protection by Acidified Maalox against Indomethacin-Induced Gastric Antral Ulceration in Hamsters

Digestion / Jan 01, 1991

Fitzpatrick, L. R. (1991). Protection by Acidified Maalox against Indomethacin-Induced Gastric Antral Ulceration in Hamsters. Digestion, 50(1), 1–6. Portico. https://doi.org/10.1159/000200733

Tu1744 - Ex Vivo Effects of Ror-Gamma T Inhibitors on Proinflammatory Cytokine Secretion from Colonic Strips of Mice with DSS-Induced Colitis

Gastroenterology / May 01, 2018

Fitzpatrick, L. R., Talbott, G., Buhr, C. A., Alton, G., & Zapf, J. (2018). Tu1744 - Ex Vivo Effects of Ror-Gamma T Inhibitors on Proinflammatory Cytokine Secretion from Colonic Strips of Mice with DSS-Induced Colitis. Gastroenterology, 154(6), S-1007-S-1008. https://doi.org/10.1016/s0016-5085(18)33370-5

A Novel ROR-Gamma T Inhibitor (VPR-254) Attenuates Key Parameters of Innate Immune Colitis in Mice

Gastroenterology / Apr 01, 2017

Fitzpatrick, L. R., O’Connell, R., Talbott, G., Bendele, P., Alton, G., & Zapf, J. (2017). A Novel ROR-Gamma T Inhibitor (VPR-254) Attenuates Key Parameters of Innate Immune Colitis in Mice. Gastroenterology, 152(5), S30–S31. https://doi.org/10.1016/s0016-5085(17)30468-7

Sa1834 Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Macrophage and Colonic Epithelial Cell Lines

Gastroenterology / Apr 01, 2016

Fitzpatrick, L. R., Talbott, G., & Woldemariam, T. (2016). Sa1834 Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Macrophage and Colonic Epithelial Cell Lines. Gastroenterology, 150(4), S376–S377. https://doi.org/10.1016/s0016-5085(16)31323-3

90 Efficacy of a Novel Small Molecule RORgt Inverse Agonist in Mouse DSS and TNBS Models of Inflammatory Bowel Disease

Gastroenterology / Apr 01, 2015

Fitzpatrick, L. R., Zapf, J., Flood, E. M., Ravula, S. B., Lingardo, L. K., Small, J., Tucci, F., Buhr, C. A., & Alton, G. (2015). 90 Efficacy of a Novel Small Molecule RORgt Inverse Agonist in Mouse DSS and TNBS Models of Inflammatory Bowel Disease. Gastroenterology, 148(4), S-26. https://doi.org/10.1016/s0016-5085(15)30090-1

Sa2053 Bacillus Coagulans Bc30 Limits the Recurrence of Clostridium diJicile-Induced Colitis Following Vancomycin Withdrawal in Mice

Gastroenterology / May 01, 2012

Fitzpatrick, L. R., Small, J. S., Greene, W., Karpa, K., & Keller, D. (2012). Sa2053 Bacillus Coagulans Bc30 Limits the Recurrence of Clostridium diJicile-Induced Colitis Following Vancomycin Withdrawal in Mice. Gastroenterology, 142(5), S-390. https://doi.org/10.1016/s0016-5085(12)61479-6

M1651 Melanin-Concentrating Hormone Receptor 1 Antagonists Attenuate TNBS-Induced Colitis in Mice

Gastroenterology / May 01, 2009

Fitzpatrick, L. R., Small, J. S., & Zhang, G. (2009). M1651 Melanin-Concentrating Hormone Receptor 1 Antagonists Attenuate TNBS-Induced Colitis in Mice. Gastroenterology, 136(5), A-403. https://doi.org/10.1016/s0016-5085(09)61850-3

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Digestive Diseases and Sciences / Jan 01, 2003

Fitzpatrick, L. R., Wang, J., Le, T., & Calingasan, N. (2003). Digestive Diseases and Sciences, 48(4), 775–782. https://doi.org/10.1023/a:1022853213009

A comparison of sucralfate and bismuth subsalicylate formulations in rabbit esophageal models

Gastroenterology / Apr 01, 1995

A comparison of sucralfate and bismuth subsalicylate formulations in rabbit esophageal models. (1995). Gastroenterology, 108(4), A94. https://doi.org/10.1016/0016-5085(95)23040-8

Tu1617 The Synthetic Triterpenoid (CDDO-IM) Inhibits STAT3, As Well As IL-17, and Improves DSS-Induced Colitis in Mice

Gastroenterology / May 01, 2013

Stonesifer, E., Fitzpatrick, L. R., Small, J., & Liby, K. T. (2013). Tu1617 The Synthetic Triterpenoid (CDDO-IM) Inhibits STAT3, As Well As IL-17, and Improves DSS-Induced Colitis in Mice. Gastroenterology, 144(5), S-807. https://doi.org/10.1016/s0016-5085(13)62986-8

Bacillus Coagulans (Bc 30 ) Improves Some Indices of Clostridium difficile -Induced Colitis in Mice

Gastroenterology / May 01, 2011

Fitzpatrick, L. R., Small, J. S., Greene, W., Karpa, K., & Keller, D. (2011). Bacillus Coagulans (Bc 30 ) Improves Some Indices of Clostridium difficile -Induced Colitis in Mice. Gastroenterology, 140(5), S-849. https://doi.org/10.1016/s0016-5085(11)63523-3

Characterization of the reactivation phase of dextran sodium sulfate (DSS)-induced colitis in rats

Gastroenterology / Apr 01, 1998

Fitzpatrick, L. R., Williams, J., & Le. Maryland, T. (1998). Characterization of the reactivation phase of dextran sodium sulfate (DSS)-induced colitis in rats. Gastroenterology, 114, A976. https://doi.org/10.1016/s0016-5085(98)83975-9

Novel characterization and quantification of bismuth binding to gastric mucosa

Gastroenterology / Apr 01, 1995

Novel characterization and quantification of bismuth binding to gastric mucosa. (1995). Gastroenterology, 108(4), A180. https://doi.org/10.1016/0016-5085(95)23381-4

Regulation of intestinal ornithine decarboxylase (ODC) expression during postnatal development by ODC antizyme in rats

Gastroenterology / Apr 01, 2000

Lin, C.-H., Tolia, V. K., & Vijesurier, R. M. (2000). Regulation of intestinal ornithine decarboxylase (ODC) expression during postnatal development by ODC antizyme in rats. Gastroenterology, 118(4), A292. https://doi.org/10.1016/s0016-5085(00)83253-9

Ex Vivo Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Colonic Strips of Mice with Dssinduced Colitis

Gastroenterology / Apr 01, 2017

Fitzpatrick, L. R., Talbott, G., Mokrushin, E., & Woldemariam, T. (2017). Ex Vivo Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Colonic Strips of Mice with Dssinduced Colitis. Gastroenterology, 152(5), S571. https://doi.org/10.1016/s0016-5085(17)32067-x

P012 Vidofludimus inhibits IL-17 and improves hapten-induced colitis in young rats by a unique dual mode of action

Journal of Crohn's and Colitis / Feb 01, 2012

Fitzpatrick, L. R., Small, J. S., Doblhofer, R., Henning, S. W., & Ammendola, A. (2012). P012 Vidofludimus inhibits IL-17 and improves hapten-induced colitis in young rats by a unique dual mode of action. Journal of Crohn’s and Colitis, 6, S15–S16. https://doi.org/10.1016/s1873-9946(12)60033-6

Colitis Development in IL-10 Deficient Mice Reveals a Direct Role of MCH in Regulating IL-10 Expression by Monocytes

Gastroenterology / May 01, 2011

Ziogas, D., ElKhal, A., Najarian, R. M., Mustafa, S. N., Reizes, O., Fitzpatrick, L. R., & Kokkotou, E. (2011). Colitis Development in IL-10 Deficient Mice Reveals a Direct Role of MCH in Regulating IL-10 Expression by Monocytes. Gastroenterology, 140(5), S-518. https://doi.org/10.1016/s0016-5085(11)62150-1

Alterations in amino acid uptake and transport in TNBS-induced colitis

Inflammatory Bowel Diseases / Dec 01, 2008

Puleo, F., Meng, Q., Navaratnarajah, M., Fitzpatrick, L., Koltun, W., & Cooney, R. (2008). Alterations in amino acid uptake and transport in TNBS-induced colitis: P-0016. Inflammatory Bowel Diseases, 14, S15. https://doi.org/10.1097/00054725-200812003-00051

Alterations in the IGF-I axis and ubiquitin E3 ligases (atrogin-1, MuRF1) in TNBS-induced colitis: A mechanism for loss of muscle mass in IBD

Inflammatory Bowel Diseases / Jan 01, 2008

Cooney, R., Fitzpatrick, L., Meirelles, K., Puleo, F., Koltun, W., & Lang, C. (2008). Alterations in the IGF-I axis and ubiquitin E3 ligases (atrogin-1, MuRF1) in TNBS-induced colitis: A mechanism for loss of muscle mass in IBD: P-077. Inflammatory Bowel Diseases, 14, S32. https://doi.org/10.1097/00054725-200801001-00110

S1743 Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Rats

Gastroenterology / Apr 01, 2008

Maines, L. W., Fitzpatrick, L. R., Green, C., & Smith, C. D. (2008). S1743 Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Rats. Gastroenterology, 134(4), A-261. https://doi.org/10.1016/s0016-5085(08)61214-7

Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Mice

Gastrointestinal Endoscopy / Apr 01, 2007

Maines, L. W., Fitzpatrick, L. R., Green, C. L., & Smith, C. D. (2007). Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Mice. Gastrointestinal Endoscopy, 65(5), AB263. https://doi.org/10.1016/j.gie.2007.03.621

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Marina Baretti

Baltimore, Maryland, United States of America
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
Most Relevant Research Interests
Gastroenterology
Other Research Interests (14)
Oncology
Pharmacology (medical)
Pharmacology
Hematology
Hepatology
And 9 more
About
Throughout my training, I have been focused toward my ultimate goal of becoming a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions. My clinical research is centered on the development of novel agents in GI cancers, with particular interest in combinatorial approaches of epigenetic therapies and immunotherapies combinations. I ran the first phase II study of combination epigenetic therapy and immunotherapy in advanced pancreatic adenocarcinoma and cholangiocarcinoma, working with a collaborative team that incorporates leading experts in cancer immunology, epigenetics and drug development. I was awarded the 2018 ASCO Conquer Cancer Foundation Young Investigator Award for this project.  Together with Dr. Yarchoan, we are running a clinical trial of a novel neoantigen-specific vaccine in combination with immune checkpoint inhibitors for advanced fibrolamellar carcinoma (FLC) (NCT04248569). My laboratory focus has been on developing and validating a preclinical mouse model of FLC to investigate mechanisms underlying FLC pathogenesis, and will become a critical tool for investigating novel therapeutic strategies in FLC.
Most Relevant Publications (3+)

57 total publications

Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer

Digestive and Liver Disease / Oct 01, 2015

Sefrioui, D., Sarafan-Vasseur, N., Beaussire, L., Baretti, M., Gangloff, A., Blanchard, F., Clatot, F., Sabourin, J.-C., Sesboüé, R., Frebourg, T., Michel, P., & Di Fiore, F. (2015). Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer. Digestive and Liver Disease, 47(10), 884–890. https://doi.org/10.1016/j.dld.2015.05.023

Effect of Comorbidities in Stage II/III Colorectal Cancer Patients Treated With Surgery and Neoadjuvant/Adjuvant Chemotherapy: A Single-Center, Observational Study

Clinical Colorectal Cancer / Sep 01, 2018

Baretti, M., Rimassa, L., Personeni, N., Giordano, L., Tronconi, M. C., Pressiani, T., Bozzarelli, S., & Santoro, A. (2018). Effect of Comorbidities in Stage II/III Colorectal Cancer Patients Treated With Surgery and Neoadjuvant/Adjuvant Chemotherapy: A Single-Center, Observational Study. Clinical Colorectal Cancer, 17(3), e489–e498. https://doi.org/10.1016/j.clcc.2018.03.010

Assessment of HER2 status in patients with gastroesophageal adenocarcinoma treated with epirubicin-based chemotherapy: heterogeneity-related issues and prognostic implications

Gastric Cancer / Aug 16, 2016

Personeni, N., Baretti, M., Bozzarelli, S., Spaggiari, P., Rubino, L., Tronconi, M. C., Fumagalli Romario, U., Rosati, R., Giordano, L., Roncalli, M., Santoro, A., & Rimassa, L. (2016). Assessment of HER2 status in patients with gastroesophageal adenocarcinoma treated with epirubicin-based chemotherapy: heterogeneity-related issues and prognostic implications. Gastric Cancer, 20(3), 428–437. https://doi.org/10.1007/s10120-016-0625-1

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Kayvan Najarian

Professor of Comp Med and Bioinf, Emergency Med, and Electrical and Comp Engineering
Most Relevant Research Interests
Gastroenterology
Other Research Interests (48)
biomedical inforamtics
bioinformatics
singal processing
image processing
machine learning
And 43 more
Most Relevant Publications (1+)

106 total publications

Fully automated endoscopic disease activity assessment in ulcerative colitis

Gastrointestinal Endoscopy / Mar 01, 2021

Yao, H., Najarian, K., Gryak, J., Bishu, S., Rice, M. D., Waljee, A. K., Wilkins, H. J., & Stidham, R. W. (2021). Fully automated endoscopic disease activity assessment in ulcerative colitis. Gastrointestinal Endoscopy, 93(3), 728-736.e1. https://doi.org/10.1016/j.gie.2020.08.011

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Jonathan Moore

Genome edit designer
Most Relevant Research Interests
Gastroenterology
Other Research Interests (42)
Data science
Genome editing
Bioinformatics
Evolution
Biodiversity
And 37 more
Most Relevant Publications (1+)

72 total publications

PWE-254 Is the macroscopically normal mucosa (MNM) around colorectal cancer really ‘normal’?: Abstract PWE-254 Table 1

Gut / Jun 01, 2015

Patel, A., Fang, Y., Moore, J., Williams, N., Tripathi, G., & Arasaradnam, R. (2015). PWE-254 Is the macroscopically normal mucosa (MNM) around colorectal cancer really ‘normal’?: Abstract PWE-254 Table 1. Gut, 64(Suppl 1), A324.2-A325. https://doi.org/10.1136/gutjnl-2015-309861.700

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Example gastroenterology projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on gastroenterology?

New Product Development

Collaborating with a Gastroenterology researcher can help companies develop new products related to digestive health. These researchers can provide valuable insights into the needs and preferences of patients, leading to the development of innovative and effective solutions.

Clinical Trials and Research Studies

Gastroenterology researchers can play a crucial role in conducting clinical trials and research studies for companies. Their expertise in designing and implementing studies, analyzing data, and interpreting results can contribute to the development of new treatments, medications, and diagnostic tools.

Consulting and Advisory Services

Companies can benefit from the consulting and advisory services of Gastroenterology researchers. These experts can provide guidance on regulatory compliance, market trends, and strategic decision-making, helping companies navigate the complex landscape of the healthcare industry.

Data Analysis and Insights

Gastroenterology researchers are skilled in analyzing large datasets related to digestive health. By collaborating with these experts, companies can gain valuable insights into patient demographics, treatment outcomes, and disease patterns, enabling them to make data-driven decisions and improve their products and services.

Educational and Training Programs

Companies can collaborate with Gastroenterology researchers to develop educational and training programs for healthcare professionals. These programs can enhance the knowledge and skills of medical practitioners, leading to improved patient care and better outcomes.