Work with thought leaders and academic experts in genetics
Companies can benefit from working with someone whose expertise is in the field of genetics in several ways. Firstly, they can enhance their research and development efforts by leveraging the academic researcher's knowledge and insights. The researcher can provide valuable guidance in designing experiments, analyzing data, and interpreting results. Secondly, companies can tap into the researcher's expertise to develop innovative products and solutions. The researcher's deep understanding of genetics can help identify new opportunities and create cutting-edge technologies. Thirdly, collaborating with an academic researcher can enhance a company's credibility and reputation. By partnering with a recognized expert in the field, companies can demonstrate their commitment to scientific excellence and gain trust from customers and investors. Lastly, the researcher can also contribute to the company's thought leadership and industry influence. Their research findings and publications can position the company as a leader in the genetics field and attract attention from key stakeholders.
Experts on NotedSource with backgrounds in genetics include Boris Leibovitch, Michael W Harman, Daniel Milej, Ph.D., Regan Hamel, Jeffrey Townsend, Edoardo Airoldi, Giuliana Noratto, Jennifer Aaker, Ping Luo, Ariel Aptekmann, Marina Baretti, Peter Reich, Katelyn Katelyn Masiuk, Asst. Prof. Eng. Davide Verzotto, Ph.D., Kayvan Najarian, Michael Paxhia, Artemis Louyakis, Dona SLEIMAN, Matthew Laye, Ph.D., JOAQUIN GADEA, Dr. Susanne Ressl, Andrew Mikhail, Paul Schrater, Olivier Saulnier, Gianfranco Santovito, Christine Wong, Ph.D., Sally Irwin, Mehrdad Sheikhvatan, Patrick G. Grant, Ph.D., Patrick Reeson, Chai Jin Lee, Annabel Whibley, Matheus Ferraz, Ernesto Lowy, Niko Popitsch, John Joe, Nicolas Collao, Nina Esaki, Shruti Muralidhar, William Gartner, Krista Kaasik, Francesc Lopez, Diane Imburgio, Anna Koster, and Diane Imburgio.
Boris Leibovitch
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Most Relevant Research Interests
Other Research Interests (11)
About
Most Relevant Publications (9+)
22 total publications
Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster
Cold Spring Harbor Symposia on Quantitative Biology / Jan 01, 2004
HAYNES, K. A., LEIBOVITCH, B. A., RANGWALA, S. H., CRAIG, C., & ELGIN, S. C. R. (2004). Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia on Quantitative Biology, 69(0), 267–272. https://doi.org/10.1101/sqb.2004.69.267
A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene
Genetical Research / Aug 01, 2001
GRANOK, H., LEIBOVITCH, B. A., & ELGIN, S. C. R. (2001). A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene. Genetical Research, 78(1), 13–21. https://doi.org/10.1017/s0016672301005122
Chromatin organization and transcriptional control of gene expression in Drosophila
Gene / Aug 01, 2000
Farkas, G., Leibovitch, B. A., & Elgin, S. C. R. (2000). Chromatin organization and transcriptional control of gene expression in Drosophila. Gene, 253(2), 117–136. https://doi.org/10.1016/s0378-1119(00)00240-7
Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics
Journal of Neurogenetics / Jan 01, 1995
Leibovitch, B. A., Campbell, D. B., Krishnan, K. S., & Nash, H. A. (1995). Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics. Journal of Neurogenetics, 10(1), 1–13. https://doi.org/10.3109/01677069509083455
Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae
Molecular and General Genetics MGG / Nov 01, 1984
Danilevskaya, O. N., Kurenova, E. V., Leibovitch, B. A., Shevelev, A. Ya., Bass, I. A., & Khesin, R. B. (1984). Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae. Molecular and General Genetics MGG, 197(2), 342–344. https://doi.org/10.1007/bf00330983
Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster
Molecular and General Genetics MGG / Jul 01, 1980
Chernyshev, A. I., Bashkirov, V. N., Leibovitch, B. A., & Khesin, R. B. (1980). Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster. Molecular and General Genetics MGG, 178(3), 663–668. https://doi.org/10.1007/bf00337876
Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster
Molecular and General Genetics MGG / Jan 01, 1978
Khesin, R. B., & Leibovitch, B. A. (1978). Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster. Molecular and General Genetics MGG, 162(3), 323–328. https://doi.org/10.1007/bf00268858
Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila
Chromosoma / Jan 01, 1976
Leibovitch, B. A., Belyaeva, E. S., Zhimulev, I. F., & Khesin, R. B. (1976). Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila. Chromosoma, 54(4), 349–362. https://doi.org/10.1007/bf00292815
Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster
Chromosoma / Jan 01, 1974
Khesin, R. B., & Leibovitch, B. A. (1974). Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster. Chromosoma, 46(2), 161–172. https://doi.org/10.1007/bf00332514
Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Interests
Other Research Interests (16)
About
Most Relevant Publications (2+)
15 total publications
The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ
Genes & Cancer / Dec 24, 2017
Gomes, C. J., Centuori, S. M., Harman, M. W., Putnam, C. W., Wolgemuth, C. W., & Martinez, J. D. (2017). The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ. Genes & Cancer, 8(11–12), 771–783. https://doi.org/10.18632/genesandcancer.161
Vinculin in Neutrophil Adhesion, Motility and Trafficking
The FASEB Journal / Apr 01, 2018
Wilson, Z., Harman, M., Hazlett, L., Odzer, J., Witt, H., Franck, C., Reichner, J., & Lefort, C. (2018). Vinculin in Neutrophil Adhesion, Motility and Trafficking. The FASEB Journal, 32(S1). Portico. https://doi.org/10.1096/fasebj.2018.32.1_supplement.280.11
Daniel Milej, Ph.D.
Ph.D. in biomedical engineering
Most Relevant Research Interests
Other Research Interests (40)
About
Most Relevant Publications (1+)
91 total publications
Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions
The FASEB Journal / May 01, 2022
Shoemaker, L., Suwalski, M., Milej, D., Shoemaker, J. K., Chui, J., & St. Lawrence, K. (2022). Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3459
Regan Hamel
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
Most Relevant Research Interests
Other Research Interests (17)
About
Most Relevant Publications (1+)
12 total publications
Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice
Molecular Therapy / Dec 01, 2020
Braga, A., Bandiera, S., Verheyen, J., Hamel, R., Rutigliani, C., Edenhofer, F., Smith, J. A., & Pluchino, S. (2020). Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Molecular Therapy, 28(12), 2677–2690. https://doi.org/10.1016/j.ymthe.2020.08.001
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
Most Relevant Research Interests
Other Research Interests (76)
About
Most Relevant Publications (64+)
207 total publications
The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits
Systematic Biology / Apr 01, 2009
Schoch, C. L., Sung, G.-H., López-Giráldez, F., Townsend, J. P., Miadlikowska, J., Hofstetter, V., Robbertse, B., Matheny, P. B., Kauff, F., Wang, Z., Gueidan, C., Andrie, R. M., Trippe, K., Ciufetti, L. M., Wynns, A., Fraker, E., Hodkinson, B. P., Bonito, G., Groenewald, J. Z., … Spatafora, J. W. (2009). The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits. Systematic Biology, 58(2), 224–239. https://doi.org/10.1093/sysbio/syp020
Profiling Phylogenetic Informativeness
Systematic Biology / Apr 01, 2007
Townsend, J. P. (2007). Profiling Phylogenetic Informativeness. Systematic Biology, 56(2), 222–231. https://doi.org/10.1080/10635150701311362
Phylogenetic and phylogenomic overview of the Polyporales
Mycologia / Nov 01, 2013
Binder, M., Justo, A., Riley, R., Salamov, A., Lopez-Giraldez, F., Sjökvist, E., Copeland, A., Foster, B., Sun, H., Larsson, E., Larsson, K.-H., Townsend, J., Grigoriev, I. V., & Hibbett, D. S. (2013). Phylogenetic and phylogenomic overview of the Polyporales. Mycologia, 105(6), 1350–1373. https://doi.org/10.3852/13-003
Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays
BMC Genomics / Oct 02, 2003
Townsend, J. P. (2003). Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays. BMC Genomics, 4(1). https://doi.org/10.1186/1471-2164-4-41
Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays
Gene / May 01, 2004
Lim, C. R., Fukakusa, A., & Matsubara, K. (2004). Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays. Gene, 333, 3–13. https://doi.org/10.1016/j.gene.2004.02.026
Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes
Genetics / May 01, 2003
Townsend, J. P., Nielsen, K. M., Fisher, D. S., & Hartl, D. L. (2003). Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes. Genetics, 164(1), 13–21. https://doi.org/10.1093/genetics/164.1.13
Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa
mSystems / Jun 28, 2022
Wang, Z., Lopez-Giraldez, F., Slot, J., Yarden, O., Trail, F., & Townsend, J. P. (2022). Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa. MSystems, 7(3). https://doi.org/10.1128/msystems.00232-22
Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes
Molecular Biology and Evolution / Apr 26, 2022
Cannataro, V. L., Mandell, J. D., & Townsend, J. P. (2022). Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes. Molecular Biology and Evolution, 39(5). https://doi.org/10.1093/molbev/msac084
Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales)
Microbiology Resource Announcements / Feb 17, 2022
Gortikov, M., Wang, Z., Steindorff, A. S., Grigoriev, I. V., Druzhinina, I. S., Townsend, J. P., & Yarden, O. (2022). Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales). Microbiology Resource Announcements, 11(2). https://doi.org/10.1128/mra.00995-21
Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy
PLOS Computational Biology / Jun 09, 2021
Wells, C. R., Cao, Y., Durham, D. P., Byrareddy, S. N., Ansari, A. A., Ruddle, N. H., Townsend, J. P., Galvani, A. P., & Perelson, A. S. (2021). Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy. PLOS Computational Biology, 17(6), e1009031. https://doi.org/10.1371/journal.pcbi.1009031
Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification
Genome Biology and Evolution / Nov 16, 2020
Dornburg, A., Wang, Z., Wang, J., Mo, E. S., López-Giráldez, F., & Townsend, J. P. (2020). Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification. Genome Biology and Evolution, 13(1). https://doi.org/10.1093/gbe/evaa228
Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi
Molecular Biology and Evolution / Mar 19, 2020
Merényi, Z., Prasanna, A. N., Wang, Z., Kovács, K., Hegedüs, B., Bálint, B., Papp, B., Townsend, J. P., & Nagy, L. G. (2020). Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi. Molecular Biology and Evolution, 37(8), 2228–2240. https://doi.org/10.1093/molbev/msaa077
Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model
Systematic Biology / Oct 29, 2019
Scott, J. G., Maini, P. K., Anderson, A. R. A., & Fletcher, A. G. (2019). Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model. Systematic Biology, 69(4), 623–637. https://doi.org/10.1093/sysbio/syz070
Molecular Biology and Evolution of Cancer: From Discovery to Action
Molecular Biology and Evolution / Oct 23, 2019
Somarelli, J. A., Gardner, H., Cannataro, V. L., Gunady, E. F., Boddy, A. M., Johnson, N. A., Fisk, J. N., Gaffney, S. G., Chuang, J. H., Li, S., Ciccarelli, F. D., Panchenko, A. R., Megquier, K., Kumar, S., Dornburg, A., DeGregori, J., & Townsend, J. P. (2019). Molecular Biology and Evolution of Cancer: From Discovery to Action. Molecular Biology and Evolution, 37(2), 320–326. https://doi.org/10.1093/molbev/msz242
Modelling microbial infection to address global health challenges
Nature Microbiology / Sep 20, 2019
Fitzpatrick, M. C., Bauch, C. T., Townsend, J. P., & Galvani, A. P. (2019). Modelling microbial infection to address global health challenges. Nature Microbiology, 4(10), 1612–1619. https://doi.org/10.1038/s41564-019-0565-8
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
Oncogene / Jan 15, 2019
Cannataro, V. L., Gaffney, S. G., Sasaki, T., Issaeva, N., Grewal, N. K. S., Grandis, J. R., Yarbrough, W. G., Burtness, B., Anderson, K. S., & Townsend, J. P. (2019). APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma. Oncogene, 38(18), 3475–3487. https://doi.org/10.1038/s41388-018-0657-6
Wagging the long tail of drivers of prostate cancer
PLOS Genetics / Jan 17, 2019
Cannataro, V. L., & Townsend, J. P. (2019). Wagging the long tail of drivers of prostate cancer. PLOS Genetics, 15(1), e1007820. https://doi.org/10.1371/journal.pgen.1007820
Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets
Systematic Biology / Jun 25, 2018
Dornburg, A., Su, Z., & Townsend, J. P. (2018). Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets. Systematic Biology, 68(1), 145–156. https://doi.org/10.1093/sysbio/syy047
Somatic evolutionary timings of driver mutations
BMC Cancer / Jan 18, 2018
Gomez, K., Miura, S., Huuki, L. A., Spell, B. S., Townsend, J. P., & Kumar, S. (2018). Somatic evolutionary timings of driver mutations. BMC Cancer, 18(1). https://doi.org/10.1186/s12885-017-3977-y
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution / Apr 19, 2018
Cannataro, V. L., & Townsend, J. P. (2018). Neutral Theory and the Somatic Evolution of Cancer. Molecular Biology and Evolution, 35(6), 1308–1315. https://doi.org/10.1093/molbev/msy079
Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C
Oncogene / Feb 16, 2018
Cannataro, V. L., Gaffney, S. G., Stender, C., Zhao, Z.-M., Philips, M., Greenstein, A. E., & Townsend, J. P. (2018). Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C. Oncogene, 37(18), 2444–2455. https://doi.org/10.1038/s41388-017-0105-z
Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues
Molecular Ecology / Dec 12, 2017
Wang, Z., Wang, J., Li, N., Li, J., Trail, F., Dunlap, J. C., & Townsend, J. P. (2017). Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues. Molecular Ecology, 27(1), 216–232. Portico. https://doi.org/10.1111/mec.14425
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution / May 14, 2018
Neutral Theory and the Somatic Evolution of Cancer. (2018). Molecular Biology and Evolution, 35(6), 1561–1561. https://doi.org/10.1093/molbev/msy100
Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence
Molecular Biology and Evolution / Jul 28, 2017
Zhao, Z.-M., Campbell, M. C., Li, N., Lee, D. S. W., Zhang, Z., & Townsend, J. P. (2017). Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence. Molecular Biology and Evolution, 34(11), 3006–3022. https://doi.org/10.1093/molbev/msx213
Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana
Genetics / Aug 01, 2017
Park, B., Rutter, M. T., Fenster, C. B., Symonds, V. V., Ungerer, M. C., & Townsend, J. P. (2017). Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana. Genetics, 206(4), 2105–2117. https://doi.org/10.1534/genetics.116.199190
The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi
PLOS Genetics / Jul 13, 2017
Trail, F., Wang, Z., Stefanko, K., Cubba, C., & Townsend, J. P. (2017). The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi. PLOS Genetics, 13(7), e1006867. https://doi.org/10.1371/journal.pgen.1006867
New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset
Molecular Phylogenetics and Evolution / May 01, 2017
Dornburg, A., Townsend, J. P., Brooks, W., Spriggs, E., Eytan, R. I., Moore, J. A., Wainwright, P. C., Lemmon, A., Lemmon, E. M., & Near, T. J. (2017). New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset. Molecular Phylogenetics and Evolution, 110, 27–38. https://doi.org/10.1016/j.ympev.2017.02.017
PhyloOncology: Understanding cancer through phylogenetic analysis
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer / Apr 01, 2017
Somarelli, J. A., Ware, K. E., Kostadinov, R., Robinson, J. M., Amri, H., Abu-Asab, M., Fourie, N., Diogo, R., Swofford, D., & Townsend, J. P. (2017). PhyloOncology: Understanding cancer through phylogenetic analysis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1867(2), 101–108. https://doi.org/10.1016/j.bbcan.2016.10.006
A working model of the deep relationships of diverse modern human genetic lineages outside of Africa
Molecular Biology and Evolution / Jan 10, 2017
Lipson, M., & Reich, D. (2017). A working model of the deep relationships of diverse modern human genetic lineages outside of Africa. Molecular Biology and Evolution, msw293. https://doi.org/10.1093/molbev/msw293
Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification
Molecular Biology and Evolution / Jan 12, 2017
Wu, W. K. K., Li, X., Wang, X., Dai, R. Z. W., Cheng, A. S. L., Wang, M. H. T., Kwong, T., Chow, T. C., Yu, J., Chan, M. T. V., & Wong, S. H. (2017). Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification. Molecular Biology and Evolution, msw295. https://doi.org/10.1093/molbev/msw295
Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection
Molecular Biology and Evolution / Apr 20, 2015
Hodgins-Davis, A., Rice, D. P., & Townsend, J. P. (2015). Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection. Molecular Biology and Evolution, 32(8), 2130–2140. https://doi.org/10.1093/molbev/msv094
H-CLAP: hierarchical clustering within a linear array with an application in genetics
Statistical Applications in Genetics and Molecular Biology / Jan 01, 2015
Ghosh, S., & Townsend, J. P. (2015). H-CLAP: hierarchical clustering within a linear array with an application in genetics. Statistical Applications in Genetics and Molecular Biology, 14(2). https://doi.org/10.1515/sagmb-2013-0076
The peopling of the African continent and the diaspora into the new world
Current Opinion in Genetics & Development / Dec 01, 2014
Campbell, M. C., Hirbo, J. B., Townsend, J. P., & Tishkoff, S. A. (2014). The peopling of the African continent and the diaspora into the new world. Current Opinion in Genetics & Development, 29, 120–132. https://doi.org/10.1016/j.gde.2014.09.003
Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa
G3 Genes|Genomes|Genetics / Sep 01, 2014
Wu, C., Yang, F., Smith, K. M., Peterson, M., Dekhang, R., Zhang, Y., Zucker, J., Bredeweg, E. L., Mallappa, C., Zhou, X., Lyubetskaya, A., Townsend, J. P., Galagan, J. E., Freitag, M., Dunlap, J. C., Bell-Pedersen, D., & Sachs, M. S. (2014). Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa. G3 Genes|Genomes|Genetics, 4(9), 1731–1745. https://doi.org/10.1534/g3.114.012617
Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
PLoS Pathogens / May 08, 2014
Talbert-Slagle, K., Atkins, K. E., Yan, K.-K., Khurana, E., Gerstein, M., Bradley, E. H., Berg, D., Galvani, A. P., & Townsend, J. P. (2014). Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body. PLoS Pathogens, 10(5), e1004092. https://doi.org/10.1371/journal.ppat.1004092
Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design
Molecular Phylogenetics and Evolution / Jan 01, 2013
Moeller, A. H., & Townsend, J. P. (2013). Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design. Molecular Phylogenetics and Evolution, 66(1), 436. https://doi.org/10.1016/j.ympev.2012.09.035
Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny
Systematic Biology / Mar 03, 2012
Townsend, J. P., Su, Z., & Tekle, Y. I. (2012). Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny. Systematic Biology, 61(5), 835. https://doi.org/10.1093/sysbio/sys036
Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size
G3 Genes|Genomes|Genetics / Aug 01, 2012
Rice, D. P., & Townsend, J. P. (2012). Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size. G3 Genes|Genomes|Genetics, 2(8), 905–911. https://doi.org/10.1534/g3.112.003228
Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology
Fungal Genetics and Biology / Aug 01, 2012
Sikhakolli, U. R., López-Giráldez, F., Li, N., Common, R., Townsend, J. P., & Trail, F. (2012). Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology. Fungal Genetics and Biology, 49(8), 663–673. https://doi.org/10.1016/j.fgb.2012.05.009
Sex-specific gene expression during asexual development of Neurospora crassa
Fungal Genetics and Biology / Jul 01, 2012
Wang, Z., Kin, K., López-Giráldez, F., Johannesson, H., & Townsend, J. P. (2012). Sex-specific gene expression during asexual development of Neurospora crassa. Fungal Genetics and Biology, 49(7), 533–543. https://doi.org/10.1016/j.fgb.2012.05.004
Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa
Fungal Genetics and Biology / May 01, 2012
Wang, Z., Lehr, N., Trail, F., & Townsend, J. P. (2012). Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa. Fungal Genetics and Biology, 49(5), 405–413. https://doi.org/10.1016/j.fgb.2012.03.004
A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data
Genetics / Apr 01, 2012
Rice, D. P., & Townsend, J. P. (2012). A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data. Genetics, 190(4), 1533–1545. https://doi.org/10.1534/genetics.111.137075
Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae
Genome Biology and Evolution / Jan 01, 2012
Hodgins-Davis, A., Adomas, A. B., Warringer, J., & Townsend, J. P. (2012). Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae. Genome Biology and Evolution, 4(11), 1061–1079. https://doi.org/10.1093/gbe/evs084
Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates
Molecular Phylogenetics and Evolution / Aug 01, 2011
Moeller, A. H., & Townsend, J. P. (2011). Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates. Molecular Phylogenetics and Evolution, 60(2), 271–272. https://doi.org/10.1016/j.ympev.2011.04.023
Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference
Systematic Biology / Feb 08, 2011
Townsend, J. P., & Leuenberger, C. (2011). Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference. Systematic Biology, 60(3), 358–365. https://doi.org/10.1093/sysbio/syq097
Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny
Mycologia / Sep 01, 2010
Ohenoja, E., Wang, Z., Townsend, J. P., Mitchel, D., & Voitk, A. (2010). Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny. Mycologia, 102(5), 1089–1095. https://doi.org/10.3852/09-317
Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships
Systematic Biology / May 19, 2010
Townsend, J. P., & Lopez-Giraldez, F. (2010). Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships. Systematic Biology, 59(4), 446–457. https://doi.org/10.1093/sysbio/syq025
Identification of new molecular markers for assembling the eukaryotic tree of life
Molecular Phylogenetics and Evolution / Jun 01, 2010
Tekle, Y. I., Grant, J. R., Kovner, A. M., Townsend, J. P., & Katz, L. A. (2010). Identification of new molecular markers for assembling the eukaryotic tree of life. Molecular Phylogenetics and Evolution, 55(3), 1177–1182. https://doi.org/10.1016/j.ympev.2010.03.010
The filamentous fungal gene expression database (FFGED)
Fungal Genetics and Biology / Mar 01, 2010
Zhang, Z., & Townsend, J. P. (2010). The filamentous fungal gene expression database (FFGED). Fungal Genetics and Biology, 47(3), 199–204. https://doi.org/10.1016/j.fgb.2009.12.001
Multi-targeted priming for genome-wide gene expression assays
BMC Genomics / Aug 17, 2010
Adomas, A. B., Lopez-Giraldez, F., Clark, T. A., Wang, Z., & Townsend, J. P. (2010). Multi-targeted priming for genome-wide gene expression assays. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-477
Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences
PLoS Computational Biology / Jun 26, 2009
Zhang, Z., & Townsend, J. P. (2009). Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences. PLoS Computational Biology, 5(6), e1000421. https://doi.org/10.1371/journal.pcbi.1000421
Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies
Genome Biology and Evolution / Jan 01, 2009
Otto, W., Stadler, P. F., López-Giraldéz, F., Townsend, J. P., Lynch, V. J., & Wagner, G. P. (2009). Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies. Genome Biology and Evolution, 1, 85–98. https://doi.org/10.1093/gbe/evp010
Article Commentary: Snapshots of Tree Space
Evolutionary Bioinformatics / Jan 01, 2009
Wang, Z., López-Giréidez, F., & Townsend, J. P. (2009). Article Commentary: Snapshots of Tree Space. Evolutionary Bioinformatics, 5, EBO.S3416. https://doi.org/10.4137/ebo.s3416
The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree
Journal of Molecular Evolution / Aug 12, 2008
Townsend, J. P., López-Giráldez, F., & Friedman, R. (2008). The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree. Journal of Molecular Evolution, 67(5), 437–447. https://doi.org/10.1007/s00239-008-9142-0
Sleuthing the difference a nucleotide can make
Molecular Ecology / Jun 01, 2008
TOWNSEND, J. P. (2008). Sleuthing the difference a nucleotide can make. Molecular Ecology, 17(12), 2793–2795. https://doi.org/10.1111/j.1365-294x.2008.03824.x
Quantifying variation in gene expression
Molecular Ecology / Jul 01, 2007
CLARK, T. A., & TOWNSEND, J. P. (2007). Quantifying variation in gene expression. Molecular Ecology, 16(13), 2613–2616. https://doi.org/10.1111/j.1365-294x.2007.03354.x
Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii
Fungal Genetics and Biology / Aug 01, 2006
Johannesson, H., Kasuga, T., Schaller, R. A., Good, B., Gardner, M. J., Townsend, J. P., Cole, G. T., & Taylor, J. W. (2006). Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii. Fungal Genetics and Biology, 43(8), 545–559. https://doi.org/10.1016/j.fgb.2006.02.003
Ecological and evolutionary genomics of Saccharomyces cerevisiae
Molecular Ecology / Feb 23, 2006
LANDRY, C. R., TOWNSEND, J. P., HARTL, D. L., & CAVALIERI, D. (2006). Ecological and evolutionary genomics of Saccharomyces cerevisiae. Molecular Ecology, 15(3), 575–591. https://doi.org/10.1111/j.1365-294x.2006.02778.x
Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination
Nucleic Acids Research / Nov 27, 2005
Kasuga, T. (2005). Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination. Nucleic Acids Research, 33(20), 6469–6485. https://doi.org/10.1093/nar/gki953
Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii
Genetics / Sep 01, 2005
Johannesson, H., Townsend, J. P., Hung, C.-Y., Cole, G. T., & Taylor, J. W. (2005). Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii. Genetics, 171(1), 109–117. https://doi.org/10.1534/genetics.105.040923
Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster
Heredity / May 12, 2004
Townsend, J. P., & Rand, D. M. (2004). Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster. Heredity, 93(1), 98–103. https://doi.org/10.1038/sj.hdy.6800484
Population Genetic Variation in Genome-Wide Gene Expression
Molecular Biology and Evolution / Apr 25, 2003
Townsend, J. P. (2003). Population Genetic Variation in Genome-Wide Gene Expression. Molecular Biology and Evolution, 20(6), 955–963. https://doi.org/10.1093/molbev/msg106
Pathway Processor: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks
Genome Research / Jul 01, 2002
Grosu, P., Townsend, J. P., Hartl, D. L., & Cavalieri, D. (2002). <tt>Pathway Processor</tt>: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks. Genome Research, 12(7), 1121–1126. https://doi.org/10.1101/gr.226602
Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica
Molecular Biology and Evolution / Feb 01, 2000
Bustamante, C. D., Townsend, J. P., & Hartl, D. L. (2000). Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica. Molecular Biology and Evolution, 17(2), 301–308. https://doi.org/10.1093/oxfordjournals.molbev.a026310
Edoardo Airoldi
Professor of Statistics & Data Science Temple University & PI, Harvard University
Most Relevant Research Interests
Other Research Interests (63)
About
Most Relevant Publications (6+)
106 total publications
Post-transcriptional regulation across human tissues
PLOS Computational Biology / May 08, 2017
Franks, A., Airoldi, E., & Slavov, N. (2017). Post-transcriptional regulation across human tissues. PLOS Computational Biology, 13(5), e1005535. https://doi.org/10.1371/journal.pcbi.1005535
Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data
Molecular Biology and Evolution / Mar 14, 2013
Wallace, E. W. J., Airoldi, E. M., & Drummond, D. A. (2013). Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data. Molecular Biology and Evolution, 30(6), 1438–1453. https://doi.org/10.1093/molbev/mst051
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells
PLoS Computational Biology / Dec 16, 2010
Markowetz, F., Mulder, K. W., Airoldi, E. M., Lemischka, I. R., & Troyanskaya, O. G. (2010). Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells. PLoS Computational Biology, 6(12), e1001034. https://doi.org/10.1371/journal.pcbi.1001034
Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
PLOS Genetics / May 07, 2015
Csárdi, G., Franks, A., Choi, D. S., Airoldi, E. M., & Drummond, D. A. (2015). Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast. PLOS Genetics, 11(5), e1005206. https://doi.org/10.1371/journal.pgen.1005206
Predicting Cellular Growth from Gene Expression Signatures
PLoS Computational Biology / Jan 02, 2009
Airoldi, E. M., Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., & Troyanskaya, O. G. (2009). Predicting Cellular Growth from Gene Expression Signatures. PLoS Computational Biology, 5(1), e1000257. https://doi.org/10.1371/journal.pcbi.1000257
Getting Started in Probabilistic Graphical Models
PLoS Computational Biology / Dec 07, 2007
Airoldi, E. M. (2007). Getting Started in Probabilistic Graphical Models. PLoS Computational Biology, 3(12), e252. https://doi.org/10.1371/journal.pcbi.0030252
Giuliana Noratto
Food Scientist PhD and Registered Dietician - Texas A&M University
Most Relevant Research Interests
Other Research Interests (47)
About
Most Relevant Publications (23+)
91 total publications
Quinoa protective effects against obesity‐induced intestinal inflammation
The FASEB Journal / Apr 01, 2015
Noratto, G., Carrion‐Rabanal, R., Medina, G., Mencia, A., Mohanty, I., Gonzalez, D., & Murphy, K. (2015). Quinoa protective effects against obesity‐induced intestinal inflammation. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.602.9
Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells
The FASEB Journal / Mar 01, 2006
Mo, H., Noratto, G., Fernandes, N., Hussein, D., Sodhani, S., & Cisneros‐Zevallos, L. (2006). Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells. The FASEB Journal, 20(4). Portico. https://doi.org/10.1096/fasebj.20.4.a565-b
Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD)
The FASEB Journal / Apr 01, 2015
Ravisankar, S., Campos Gutierrez, D., Chirinos, R., & Noratto, G. (2015). Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD). The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.923.10
Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia
The FASEB Journal / Apr 01, 2013
Noratto, G., Condezo‐Hoyos, L., Gasco, M., & Gonzales, G. (2013). Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.861.25
Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice
The FASEB Journal / Apr 01, 2015
Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283
Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice
The FASEB Journal / Apr 01, 2015
Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283
Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5)
The FASEB Journal / Apr 01, 2014
Yuan, J., Noratto, K., Munske, G., Pilla, P., Mohanty, I., Alcantara Zapata, D., & Noratto, G. (2014). Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1018.5
Quinoa as source of bioactive compounds with potential for intestinal health (647.18)
The FASEB Journal / Apr 01, 2014
Carrion, R., Murphy, K., Ganjyal, G., Kowalski, R., & Noratto, G. (2014). Quinoa as source of bioactive compounds with potential for intestinal health (647.18). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.647.18
Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells
The FASEB Journal / Apr 01, 2009
Del Follo, A., Noratto, G. D., & Mertens‐Talcott, S. (2009). Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.4
Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells
The FASEB Journal / Apr 01, 2009
Townsley, E. D., Noratto, G., Angel, G., Del Follo, A., Byrne, D., & Mertens‐Talcott, S. (2009). Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.12
Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity
The FASEB Journal / Apr 01, 2015
yuan, jialing, chew, B., & noratto, giuliana. (2015). Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.276.7
Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice
The FASEB Journal / Apr 01, 2015
Noratto, G., García‐Pérez, E., Ivanov, I., & Mills, D. (2015). Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.385.5
The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3)
The FASEB Journal / Apr 01, 2014
Bibi, S., Balemba, O., Carrion‐Rabanal, R., Nyavor, Y., & Noratto, G. (2014). The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.259.3
Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk
The FASEB Journal / Apr 01, 2012
Noratto, G. D., Chirinos, R., Campos, D., Larondelle, Y., Arbizu, S., Dos Santos, M. M., & Mertens-Talcott, S. (2012). Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.626.13
Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target
The FASEB Journal / Apr 01, 2015
Ravisankar, S., & Noratto, G. (2015). Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.130.7
Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice
The FASEB Journal / Apr 01, 2015
Mohanty, I., yuan, J., Noratto, G., Balemba, O., & Morris, C. (2015). Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.254.3
Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12)
The FASEB Journal / Apr 01, 2014
Ravisankar, S., Yuan, J., Munske, G., & Noratto, G. (2014). Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1034.12
Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7)
The FASEB Journal / Apr 01, 2014
Noratto, G., Mohanty, I., Alcantara Zapata, D., & Chew, B. (2014). Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.249.7
Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes
The FASEB Journal / Apr 01, 2013
Martino, H., Noratto, G., Dias, M., Talcott, S., & Mertens‐Talcott, S. (2013). Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.865.5
Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats
The FASEB Journal / Apr 01, 2012
Noratto, G. D., Simbo, S., Martino, H. S., Byrne, D., & Mertens-Talcott, S. (2012). Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.364.3
Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a
The FASEB Journal / Apr 01, 2011
Noratto, G. D., Simbo, S. Y., Safe, S., & Mertens‐Talcott, S. U. (2011). Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a. The FASEB Journal, 25(S1). Portico. https://doi.org/10.1096/fasebj.25.1_supplement.213.4
Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC)
The FASEB Journal / Apr 01, 2010
Angel‐Morales, G., Noratto, G., & Mertens‐Talcott, S. (2010). Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC). The FASEB Journal, 24(S1). Portico. https://doi.org/10.1096/fasebj.24.1_supplement.924.5
Technical note: Optimization of lactose quantification based on coupled enzymatic reactions
Journal of Dairy Science / Apr 01, 2014
Condezo-Hoyos, L., Mohanty, I. P., & Noratto, G. D. (2014). Technical note: Optimization of lactose quantification based on coupled enzymatic reactions. Journal of Dairy Science, 97(4), 2066–2070. https://doi.org/10.3168/jds.2013-7436
Jennifer Aaker
General Atlantic Professor, Stanford University
Most Relevant Research Interests
Other Research Interests (38)
About
Most Relevant Publications (1+)
79 total publications
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG
Advances in Enzyme Regulation / Jan 01, 2002
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG. (2002). Advances in Enzyme Regulation, 42, EX17. https://doi.org/10.1016/s0065-2571(01)00055-3
Ping Luo
Postdoctoral Researcher at Princess Margaret Cancer Centre with experience in deep learning
Most Relevant Research Interests
Other Research Interests (25)
About
Most Relevant Publications (5+)
23 total publications
deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks
Frontiers in Genetics / Jan 29, 2019
Luo, P., Ding, Y., Lei, X., & Wu, F.-X. (2019). deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00013
Disease Gene Prediction by Integrating PPI Networks, Clinical RNA-Seq Data and OMIM Data
IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jan 01, 2019
Luo, P., Tian, L.-P., Ruan, J., & Wu, F.-X. (2019). Disease Gene Prediction by Integrating PPI Networks, Clinical RNA-Seq Data and OMIM Data. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 16(1), 222–232. https://doi.org/10.1109/tcbb.2017.2770120
Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning
Frontiers in Genetics / Apr 02, 2019
Luo, P., Xiao, Q., Wei, P.-J., Liao, B., & Wu, F.-X. (2019). Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00270
CReSCENT: CanceR Single Cell ExpressioN Toolkit
Nucleic Acids Research / Jun 01, 2020
Mohanraj, S., Díaz-Mejía, J. J., Pham, M. D., Elrick, H., Husić, M., Rashid, S., Luo, P., Bal, P., Lu, K., Patel, S., Mahalanabis, A., Naidas, A., Christensen, E., Croucher, D., Richards, L. M., Shooshtari, P., Brudno, M., Ramani, A. K., & Pugh, T. J. (2020). CReSCENT: CanceR Single Cell ExpressioN Toolkit. Nucleic Acids Research, 48(W1), W372–W379. https://doi.org/10.1093/nar/gkaa437
Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets
Computational and Structural Biotechnology Journal / Jan 01, 2022
Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029
Ariel Aptekmann
Bioinformatician at Hackensack Meridian Hospital Center for Discovery and Innovation
Most Relevant Research Interests
Other Research Interests (37)
About
Most Relevant Publications (1+)
24 total publications
Decoding the effects of synonymous variants
Nucleic Acids Research / Nov 30, 2021
Zeng, Z., Aptekmann, A. A., & Bromberg, Y. (2021). Decoding the effects of synonymous variants. Nucleic Acids Research, 49(22), 12673–12691. https://doi.org/10.1093/nar/gkab1159
Marina Baretti
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
Most Relevant Research Interests
Other Research Interests (19)
About
Most Relevant Publications (1+)
57 total publications
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence
Clinical Epigenetics / Dec 01, 2022
Heumann, T. R., Baretti, M., Sugar, E. A., Durham, J. N., Linden, S., Lopez-Vidal, T. Y., Leatherman, J., Cope, L., Sharma, A., Weekes, C. D., O’Dwyer, P. J., Reiss, K. A., Monga, D. K., Ahuja, N., & Azad, N. S. (2022). A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence. Clinical Epigenetics, 14(1). https://doi.org/10.1186/s13148-022-01367-8
Peter Reich
Director of the Institute for Global Change Biology (IGCB)
Most Relevant Research Interests
Other Research Interests (44)
About
Most Relevant Publications (7+)
509 total publications
Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment
Molecular Ecology / Jul 29, 2016
Nguyen, N. H., Williams, L. J., Vincent, J. B., Stefanski, A., Cavender-Bares, J., Messier, C., Paquette, A., Gravel, D., Reich, P. B., & Kennedy, P. G. (2016). Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment. Molecular Ecology, 25(16), 4032–4046. Portico. https://doi.org/10.1111/mec.13719
Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output
American Journal of Botany / Oct 01, 2015
Jacques, M.-H., Lapointe, L., Rice, K., Montgomery, R. A., Stefanski, A., & Reich, P. B. (2015). Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output. American Journal of Botany, 102(10), 1610–1624. Portico. https://doi.org/10.3732/ajb.1500046
Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities
Mycologia / Jul 01, 2009
Dickie, I. A., Dentinger, B. T. M., Avis, P. G., McLaughlin, D. J., & Reich, P. B. (2009). Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities. Mycologia, 101(4), 473–483. https://doi.org/10.3852/08-178
Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen
Physiologia Plantarum / Aug 01, 1996
Volin, J. C., & Reich, P. B. (1996). Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen. Physiologia Plantarum, 97(4), 674–684. https://doi.org/10.1034/j.1399-3054.1996.970407.x
Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings
Physiologia Plantarum / Dec 01, 1993
Kruger, E. L., & Reich, P. B. (1993). Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings. Physiologia Plantarum, 89(4), 751–760. https://doi.org/10.1111/j.1399-3054.1993.tb05281.x
Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean
Physiologia Plantarum / Jan 01, 1985
Reich, P. B., Schoettle, A. W., & Amundson, R. G. (1985). Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean. Physiologia Plantarum, 63(1), 58–64. https://doi.org/10.1111/j.1399-3054.1985.tb02818.x
Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark
Physiologia Plantarum / Aug 01, 1984
Reich, P. B. (1984). Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark. Physiologia Plantarum, 61(4), 541–548. https://doi.org/10.1111/j.1399-3054.1984.tb05167.x
Katelyn Katelyn Masiuk
Co-Founder and CSO at Immunovec
Most Relevant Research Interests
Other Research Interests (23)
About
Most Relevant Publications (5+)
13 total publications
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates
Molecular Therapy / Aug 01, 2019
Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome
Cell Stem Cell / Feb 01, 2019
Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003
PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector
Molecular Therapy - Methods & Clinical Development / Jun 01, 2019
Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods & Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005
Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells
Molecular Therapy / Sep 01, 2017
Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023
Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study
Human Gene Therapy / Oct 01, 2018
Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061
Asst. Prof. Eng. Davide Verzotto, Ph.D.
Assistant Professor of Computer Science, Centre for Higher Defence Studies (CASD) - School of Advanced Studies, Italian Defence General Staff, Rome
Most Relevant Research Interests
Other Research Interests (22)
About
Most Relevant Publications (4+)
40 total publications
The Irredundant Class Method for Remote Homology Detection of Protein Sequences
Journal of Computational Biology / Dec 01, 2011
Comin, M., & Verzotto, D. (2011). The Irredundant Class Method for Remote Homology Detection of Protein Sequences. Journal of Computational Biology, 18(12), 1819–1829. https://doi.org/10.1089/cmb.2010.0171
Beyond Fixed-Resolution Alignment-Free Measures for Mammalian Enhancers Sequence Comparison
IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jul 01, 2014
Comin, M., & Verzotto, D. (2014). Beyond Fixed-Resolution Alignment-Free Measures for Mammalian Enhancers Sequence Comparison. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(4), 628–637. https://doi.org/10.1109/tcbb.2014.2306830
2014 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 11
IEEE/ACM Transactions on Computational Biology and Bioinformatics / Nov 01, 2014
2014 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 11. (2014). IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(6), 1273–1292. https://doi.org/10.1109/tcbb.2014.2381091
Guest editorial for the 12th Asia Pacific Bioinformatics Conference
IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jul 01, 2014
Zhou, S., & Phoebe Chen, Y.-P. (2014). Guest editorial for the 12th Asia Pacific Bioinformatics Conference. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(4), 614–615. https://doi.org/10.1109/tcbb.2014.2327487
Kayvan Najarian
Professor of Comp Med and Bioinf, Emergency Med, and Electrical and Comp Engineering
Most Relevant Research Interests
Other Research Interests (40)
Most Relevant Publications (1+)
108 total publications
Deep learning in pharmacogenomics: from gene regulation to patient stratification
Pharmacogenomics / May 01, 2018
Kalinin, A. A., Higgins, G. A., Reamaroon, N., Soroushmehr, S., Allyn-Feuer, A., Dinov, I. D., Najarian, K., & Athey, B. D. (2018). Deep learning in pharmacogenomics: from gene regulation to patient stratification. Pharmacogenomics, 19(7), 629–650. https://doi.org/10.2217/pgs-2018-0008
Dona SLEIMAN
After completing my BS in Biochemistry in Beirut, I pursued a master’s degree in Genetics followed by a Master 2 degree in Molecular Engineering. I received my PhD in Biochemistry and Biophysics in 2013 at Paris Descartes University with the highest honors & Committee Praise. Throughout my thesis and post-doctoral experience, I have studied different aspects of protein/nucleic acid interactions using several biophysical techniques.
Most Relevant Research Interests
Other Research Interests (8)
Most Relevant Publications (1+)
4 total publications
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus
PLOS Genetics / Apr 16, 2018
Devaux, L., Sleiman, D., Mazzuoli, M.-V., Gominet, M., Lanotte, P., Trieu-Cuot, P., Kaminski, P.-A., & Firon, A. (2018). Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus. PLOS Genetics, 14(4), e1007342. https://doi.org/10.1371/journal.pgen.1007342
Matthew Laye, Ph.D.
Medical Physiology Teacher, Data Scientist, Endurance Coach, Wearable Technology Consultant, Writer About Research
Most Relevant Research Interests
Other Research Interests (26)
Most Relevant Publications (4+)
55 total publications
Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners
Disease Markers / Jan 01, 2015
Laye, M. J., Nielsen, M. B., Hansen, L. S., Knudsen, T., & Pedersen, B. K. (2015). Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners. Disease Markers, 2015, 1–11. https://doi.org/10.1155/2015/806418
Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation
The FASEB Journal / Apr 01, 2009
Park, Y., Lee, S., Booth, F. W., Laye, M. J., & Zhang, C. (2009). Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.952.4
Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running
The FASEB Journal / Apr 01, 2007
Borengasser, S. J., Laye, M., Morris, T., Booth, F., & Thyfault, J. (2007). Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running. The FASEB Journal, 21(5). Portico. https://doi.org/10.1096/fasebj.21.5.a691-a
Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats
The FASEB Journal / Jan 01, 2007
Laye, M. J., Borengasser, S. J., Rector, R. S., Thyfault, J. P., & Booth, F. W. (2007). Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats. The FASEB Journal, 21(6). Portico. https://doi.org/10.1096/fasebj.21.6.a936
JOAQUIN GADEA
Professor in Physiology. Universidad de Murcia. SPAIN.
Most Relevant Research Interests
Other Research Interests (25)
Most Relevant Publications (10+)
90 total publications
Glycosidase determination in bovine oviducal fluid at the follicular and luteal phases of the oestrous cycle
Reproduction, Fertility and Development / Jan 01, 2008
Carrasco, L. C., Coy, P., Avilés, M., Gadea, J., & Romar, R. (2008). Glycosidase determination in bovine oviducal fluid at the follicular and luteal phases of the oestrous cycle. Reproduction, Fertility and Development, 20(7), 808. https://doi.org/10.1071/rd08113
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome
Cell Discovery / Mar 19, 2019
Dorado, B., Pløen, G. G., Barettino, A., Macías, A., Gonzalo, P., Andrés-Manzano, M. J., González-Gómez, C., Galán-Arriola, C., Alfonso, J. M., Lobo, M., López-Martín, G. J., Molina, A., Sánchez-Sánchez, R., Gadea, J., Sánchez-González, J., Liu, Y., Callesen, H., Filgueiras-Rama, D., Ibáñez, B., … Andrés, V. (2019). Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome. Cell Discovery, 5(1). https://doi.org/10.1038/s41421-019-0084-z
225 DOES THE SUPPLEMENTATION OF THE BOAR SEMEN EXTENDER WITH CARNOSINE, L-HISTIDINE, AND TAURINE PRESERVE SPERM FUNCTION DURING STORAGE?
Reproduction, Fertility and Development / Jan 01, 2008
Matás, C., Gardón, J. C., Garcia-Vazquez, F. A., Pacchini, S., & Ducci, M. (2008). 225 DOES THE SUPPLEMENTATION OF THE BOAR SEMEN EXTENDER WITH CARNOSINE, L-HISTIDINE, AND TAURINE PRESERVE SPERM FUNCTION DURING STORAGE? Reproduction, Fertility and Development, 20(1), 192. https://doi.org/10.1071/rdv20n1ab225
94 ADDITION OF REDUCED GLUTATHIONE TO THAWING MEDIUM IMPROVED THE SPERM MOTILITY AND REDUCED ROS GENERATION IN FROZEN OVINE AND CAPRINE SPERMATOZOA
Reproduction, Fertility and Development / Jan 01, 2006
Gardón, J. C., Rodriquez, J. A., & Gadea, J. (2006). 94 ADDITION OF REDUCED GLUTATHIONE TO THAWING MEDIUM IMPROVED THE SPERM MOTILITY AND REDUCED ROS GENERATION IN FROZEN OVINE AND CAPRINE SPERMATOZOA. Reproduction, Fertility and Development, 18(2), 155. https://doi.org/10.1071/rdv18n2ab94
Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination
The CRISPR Journal / Feb 01, 2021
Navarro-Serna, S., Hachem, A., Canha-Gouveia, A., Hanbashi, A., Garrappa, G., Lopes, J. S., París-Oller, E., Sarrías-Gil, L., Flores-Flores, C., Bassett, A., Sánchez, R., Bermejo-Álvarez, P., Matás, C., Romar, R., Parrington, J., & Gadea, J. (2021). Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination. The CRISPR Journal, 4(1), 132–146. https://doi.org/10.1089/crispr.2020.0078
The use of a virtual journal club to promote cross-cultural learning in the reproductive sciences
Journal of Assisted Reproduction and Genetics / Sep 24, 2018
Duncan, F. E., Romar, R., Gadea, J., Kimelman, D., Wallach, H. D., Woodruff, T. K., & Jiménez-Movilla, M. (2018). The use of a virtual journal club to promote cross-cultural learning in the reproductive sciences. Journal of Assisted Reproduction and Genetics, 35(12), 2141–2147. https://doi.org/10.1007/s10815-018-1309-z
Total urokinase-type plasminogen activator (uPA) levels in seminal plasma are associated with positive assisted reproductive technology outcomes
Journal of Assisted Reproduction and Genetics / Mar 23, 2018
Martinez-Soto, J. C., Landeras, J., Mollá, M., Mondejar, I., Nicolás, M., Fernández-Olmedilla, L., Trabalón, M., Coy, P., & Gadea, J. (2018). Total urokinase-type plasminogen activator (uPA) levels in seminal plasma are associated with positive assisted reproductive technology outcomes. Journal of Assisted Reproduction and Genetics, 35(6), 1091–1101. https://doi.org/10.1007/s10815-018-1164-y
Considerations of viscosity in the preliminaries to mammalian fertilisation
Journal of Assisted Reproduction and Genetics / Jan 14, 2011
Hunter, R. H. F., Coy, P., Gadea, J., & Rath, D. (2011). Considerations of viscosity in the preliminaries to mammalian fertilisation. Journal of Assisted Reproduction and Genetics, 28(3), 191–197. https://doi.org/10.1007/s10815-010-9531-3
Effects of men and recipients’ age on the reproductive outcome of an oocyte donation program
Journal of Assisted Reproduction and Genetics / Sep 01, 2008
Campos, I., Gómez, E., Fernández-Valencia, A. L., Landeras, J., González, R., Coy, P., & Gadea, J. (2008). Effects of men and recipients’ age on the reproductive outcome of an oocyte donation program. Journal of Assisted Reproduction and Genetics, 25(9–10), 445–452. https://doi.org/10.1007/s10815-008-9255-9
Effect of exogenous DNA on bovine sperm functionality using the sperm mediated gene transfer (SMGT) technique
Molecular Reproduction and Development / Jun 21, 2010
Canovas, S., Gutierrez-Adan, A., & Gadea, J. (2010). Effect of exogenous DNA on bovine sperm functionality using the sperm mediated gene transfer (SMGT) technique. Molecular Reproduction and Development, 77(8), 687–698. https://doi.org/10.1002/mrd.21205
Dr. Susanne Ressl
Biochemist & Structural Biologist | Project & Team Leader | Creative & Translational Thinker | Problem Solver | Mentor | Educator | Consultant | Innovator | Science Communicator & Writer | Relationship Builder | Collaborator
Most Relevant Research Interests
Other Research Interests (43)
Most Relevant Publications (2+)
20 total publications
Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila
G3 Genes|Genomes|Genetics / Dec 01, 2020
Song, W., Ressl, S., & Tracey, W. D. (2020). Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila. G3 Genes|Genomes|Genetics, 10(12), 4425–4438. https://doi.org/10.1534/g3.120.401767
C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins
The FASEB Journal / Dec 18, 2020
Sticco, M. J., Peña Palomino, P. A., Lukacsovich, D., Thompson, B. L., Földy, C., Ressl, S., & Martinelli, D. C. (2020). C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins. The FASEB Journal, 35(1). Portico. https://doi.org/10.1096/fj.202000351rr
Andrew Mikhail
Department of Kinesiology, McMaster University
Most Relevant Research Interests
Other Research Interests (20)
Most Relevant Publications (5+)
14 total publications
Acute, next‐generation
AMPK activation initiates
a disease‐resistant gene expression
program in dystrophic skeletal
muscle
The FASEB Journal / Apr 05, 2023
Ng, S. Y., Mikhail, A. I., Mattina, S. R., Manta, A., Diffey, I. J., & Ljubicic, V. (2023). Acute, next‐generation <scp>AMPK</scp> activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle. The FASEB Journal, 37(5). Portico. https://doi.org/10.1096/fj.202201846rr
Dysregulation of Skeletal Muscle Mitochondrial Turnover and Dynamics Occurs During Late Symptomatic Stages of Spinal Muscular Atrophy
The FASEB Journal / May 01, 2022
Mikhail, A. I., Ng, S. Y., Osborne, A. K., Canteenwala, A. K., & Ljubicic, V. (2022). Dysregulation of Skeletal Muscle Mitochondrial Turnover and Dynamics Occurs During Late Symptomatic Stages of Spinal Muscular Atrophy. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r2886
Characterization of CARM1 Inhibition in Skeletal Muscle
The FASEB Journal / May 01, 2022
Webb, E. K., Ng, S. Y., Stouth, D. W., Lieshout, T. L., Mikhail, A. I., & Ljubicic, V. (2022). Characterization of CARM1 Inhibition in Skeletal Muscle. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3187
A Single Dose of Exercise Initiates Corrective Mitochondrial Plasticity in Myotonic Dystrophy Type 1
The FASEB Journal / May 01, 2021
Mikhail, A., Manta, A., & Ljubicic, V. (2021). A Single Dose of Exercise Initiates Corrective Mitochondrial Plasticity in Myotonic Dystrophy Type 1. The FASEB Journal, 35(S1). Portico. https://doi.org/10.1096/fasebj.2021.35.s1.01495
Acute exercise stimulates AMPK and corrects some disease characteristics in the skeletal muscle of myotonic dystrophy type 1 mice
The FASEB Journal / May 01, 2021
Manta, A., Ng, S., Mikhail, A., Mackie, M., & Ljubicic, V. (2021). Acute exercise stimulates AMPK and corrects some disease characteristics in the skeletal muscle of myotonic dystrophy type 1 mice. The FASEB Journal, 35(S1). Portico. https://doi.org/10.1096/fasebj.2021.35.s1.04602
Paul Schrater
University of Minnesota
Most Relevant Research Interests
Other Research Interests (45)
Most Relevant Publications (8+)
96 total publications
How Haptic Size Sensations Improve Distance Perception
PLoS Computational Biology / Jun 30, 2011
Battaglia, P. W., Kersten, D., & Schrater, P. R. (2011). How Haptic Size Sensations Improve Distance Perception. PLoS Computational Biology, 7(6), e1002080. https://doi.org/10.1371/journal.pcbi.1002080
Auditory Frequency and Intensity Discrimination Explained Using a Cortical Population Rate Code
PLoS Computational Biology / Nov 14, 2013
Micheyl, C., Schrater, P. R., & Oxenham, A. J. (2013). Auditory Frequency and Intensity Discrimination Explained Using a Cortical Population Rate Code. PLoS Computational Biology, 9(11), e1003336. https://doi.org/10.1371/journal.pcbi.1003336
Grasping Objects with Environmentally Induced Position Uncertainty
PLoS Computational Biology / Oct 16, 2009
Christopoulos, V. N., & Schrater, P. R. (2009). Grasping Objects with Environmentally Induced Position Uncertainty. PLoS Computational Biology, 5(10), e1000538. https://doi.org/10.1371/journal.pcbi.1000538
Dynamic Integration of Value Information into a Common Probability Currency as a Theory for Flexible Decision Making
PLOS Computational Biology / Sep 22, 2015
Christopoulos, V., & Schrater, P. R. (2015). Dynamic Integration of Value Information into a Common Probability Currency as a Theory for Flexible Decision Making. PLOS Computational Biology, 11(9), e1004402. https://doi.org/10.1371/journal.pcbi.1004402
Task-Specific Response Strategy Selection on the Basis of Recent Training Experience
PLoS Computational Biology / Jan 02, 2014
Fulvio, J. M., Green, C. S., & Schrater, P. R. (2014). Task-Specific Response Strategy Selection on the Basis of Recent Training Experience. PLoS Computational Biology, 10(1), e1003425. https://doi.org/10.1371/journal.pcbi.1003425
Within- and Cross-Modal Distance Information Disambiguate Visual Size-Change Perception
PLoS Computational Biology / Mar 05, 2010
Battaglia, P. W., Di Luca, M., Ernst, M. O., Schrater, P. R., Machulla, T., & Kersten, D. (2010). Within- and Cross-Modal Distance Information Disambiguate Visual Size-Change Perception. PLoS Computational Biology, 6(3), e1000697. https://doi.org/10.1371/journal.pcbi.1000697
Structure Learning in Human Sequential Decision-Making
PLoS Computational Biology / Dec 02, 2010
Acuña, D. E., & Schrater, P. (2010). Structure Learning in Human Sequential Decision-Making. PLoS Computational Biology, 6(12), e1001003. https://doi.org/10.1371/journal.pcbi.1001003
Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans
PLOS Computational Biology / Oct 01, 2021
Enachescu, V., Schrater, P., Schaal, S., & Christopoulos, V. (2021). Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans. PLOS Computational Biology, 17(10), e1009429. https://doi.org/10.1371/journal.pcbi.1009429
Olivier Saulnier
The Hospital for Sick Children
Most Relevant Research Interests
Other Research Interests (17)
Most Relevant Publications (3+)
25 total publications
The LIN28B –let‐7–PBK
pathway is essential for group 3
medulloblastoma tumor growth and
survival
Molecular Oncology / Aug 07, 2023
Shahab, S. W., Roggeveen, C. M., Sun, J., Kunhiraman, H., McSwain, L. F., Juraschka, K., Kumar, S. A., Saulnier, O., Taylor, M. D., Schniederjan, M., Schnepp, R. W., MacDonald, T. J., & Kenney, A. M. (2023). The <scp>LIN28B</scp>–let‐7–<scp>PBK</scp> pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology. Portico. https://doi.org/10.1002/1878-0261.13477
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion
Nucleic Acids Research / May 01, 2021
Saulnier, O., Guedri-Idjouadiene, K., Aynaud, M.-M., Chakraborty, A., Bruyr, J., Pineau, J., O’Grady, T., Mirabeau, O., Grossetête, S., Galvan, B., Claes, M., Al Oula Hassoun, Z., Sadacca, B., Laud, K., Zaïdi, S., Surdez, D., Baulande, S., Rambout, X., Tirode, F., … Dequiedt, F. (2021). ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion. Nucleic Acids Research, 49(9), 5038–5056. https://doi.org/10.1093/nar/gkab305
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin
Nucleic Acids Research / Jan 16, 2020
Tanaka, I., Chakraborty, A., Saulnier, O., Benoit-Pilven, C., Vacher, S., Labiod, D., Lam, E. W. F., Bièche, I., Delattre, O., Pouzoulet, F., Auboeuf, D., Vagner, S., & Dutertre, M. (2020). ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin. Nucleic Acids Research, 48(5), 2676–2693. https://doi.org/10.1093/nar/gkz1213
Gianfranco Santovito
Associate Professor of Physiology at the University of Padova
Most Relevant Research Interests
Other Research Interests (75)
Most Relevant Publications (2+)
149 total publications
Cadmium metallothionein gene of Tetrahymena pyriformis
Gene / Jun 01, 1999
Piccinni, E., Bertaggia, D., Santovito, G., Miceli, C., & Kraev, A. (1999). Cadmium metallothionein gene of Tetrahymena pyriformis. Gene, 234(1), 51–59. https://doi.org/10.1016/s0378-1119(99)00181-x
The first transcriptomic resource for the Antarctic scallop Adamussium colbecki
Marine Genomics / Apr 01, 2019
Moro, G., Buonocore, F., Barucca, M., Spazzali, F., Canapa, A., Pallavicini, A., Scapigliati, G., & Gerdol, M. (2019). The first transcriptomic resource for the Antarctic scallop Adamussium colbecki. Marine Genomics, 44, 61–64. https://doi.org/10.1016/j.margen.2018.09.007
Christine Wong, Ph.D.
Science and Innovation • Neuroscientist • Co-founder of NOON
Most Relevant Research Interests
Other Research Interests (10)
Most Relevant Publications (1+)
8 total publications
Autism‐related behaviors in the cyclooxygenase‐2‐deficient mouse model
Genes, Brain and Behavior / Aug 12, 2018
Wong, C. T., Bestard‐Lorigados, I., & Crawford, D. A. (2018). Autism‐related behaviors in the cyclooxygenase‐2‐deficient mouse model. Genes, Brain and Behavior, 18(1). Portico. https://doi.org/10.1111/gbb.12506
Sally Irwin
Professor of Genetics and the Microbiome at the University of Hawaii
Most Relevant Research Interests
Other Research Interests (6)
Most Relevant Publications (1+)
3 total publications
Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce
Genome / Oct 01, 1999
Irwin, S. V., Kesseli, R. V., Waycott, W., Ryder, E. J., Cho, J. J., & Michelmore, R. W. (1999). Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce. Genome, 42(5), 982–986. https://doi.org/10.1139/g99-055
Mehrdad Sheikhvatan
Iran University of Medical Sciences
Most Relevant Research Interests
Other Research Interests (58)
Most Relevant Publications (1+)
90 total publications
Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease
Iranian Journal of Biotechnology / Jun 01, 2019
Sheikhvatan, M., boroumand, M. A., Behmanesh, M., Ziaee, S., & Cheraghee, S. (2019). Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease. Iranian Journal of Biotechnology, 17(2), 79–88. https://doi.org/10.21859/ijb.1921
Patrick G. Grant, Ph.D.
Multi Discipline Experience with Multiple Open Inovation Solutions
Most Relevant Research Interests
Other Research Interests (42)
Most Relevant Publications (2+)
41 total publications
Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2
Molecular Reproduction and Development / Jan 01, 2000
Bench, G., Corzett, M. H., Kramer, C. E., Grant, P. G., & Balhorn, R. (2000). Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2. Molecular Reproduction and Development, 56(4), 512–519. https://doi.org/10.1002/1098-2795(200008)56:4<512::aid-mrd9>3.0.co;2-m
Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae)
American Journal of Botany / Oct 01, 2001
Clark, B. M., St. Clair, L. L., Mangelson, N. F., Rees, L. B., Grant, P. G., & Bench, G. S. (2001). Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae). American Journal of Botany, 88(10), 1742–1749. Portico. https://doi.org/10.2307/3558348
Patrick Reeson
University of Victoria
Most Relevant Research Interests
Other Research Interests (18)
Most Relevant Publications (2+)
11 total publications
Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex
Cell Reports Methods / Jun 01, 2023
Reeson, P., Boghozian, R., Cota, A. P., & Brown, C. E. (2023). Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex. Cell Reports Methods, 3(6), 100489. https://doi.org/10.1016/j.crmeth.2023.100489
Ultrastructural analysis of neurons, glia and capillaries in the peri‐infarct zone of an ischemic stroke
The FASEB Journal / Apr 01, 2013
Nahirney, P. C., Reeson, P., & Brown, C. E. (2013). Ultrastructural analysis of neurons, glia and capillaries in the peri‐infarct zone of an ischemic stroke. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.533.15
Chai Jin Lee
Seoul National University
Most Relevant Research Interests
Other Research Interests (11)
Most Relevant Publications (3+)
8 total publications
Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer
BMC Medical Genomics / Feb 01, 2020
Lee, C.-J., Ahn, H., Jeong, D., Pak, M., Moon, J. H., & Kim, S. (2020). Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer. BMC Medical Genomics, 13(S3). https://doi.org/10.1186/s12920-020-0659-4
Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice
BMC Medical Genomics / Aug 01, 2016
Lee, C.-J., Ahn, H., Lee, S. B., Shin, J.-Y., Park, W.-Y., Kim, J.-I., Lee, J., Ryu, H., & Kim, S. (2016). Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice. BMC Medical Genomics, 9(S1). https://doi.org/10.1186/s12920-016-0195-4
StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis
BMC Genomics / Dec 01, 2019
Kang, D., Ahn, H., Lee, S., Lee, C.-J., Hur, J., Jung, W., & Kim, S. (2019). StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis. BMC Genomics, 20(S11). https://doi.org/10.1186/s12864-019-6283-z
Annabel Whibley
Bioinformatician at Bragato Research Institute based in Auckland, New Zealand.
Most Relevant Research Interests
Other Research Interests (18)
Most Relevant Publications (26+)
56 total publications
SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome
The American Journal of Human Genetics / Apr 01, 2008
Gilfillan, G. D., Selmer, K. K., Roxrud, I., Smith, R., Kyllerman, M., Eiklid, K., Kroken, M., Mattingsdal, M., Egeland, T., Stenmark, H., Sjøholm, H., Server, A., Samuelsson, L., Christianson, A., Tarpey, P., Whibley, A., Stratton, M. R., Futreal, P. A., Teague, J., … Strømme, P. (2008). SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome. The American Journal of Human Genetics, 82(4), 1003–1010. https://doi.org/10.1016/j.ajhg.2008.01.013
Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation
The American Journal of Human Genetics / Feb 01, 2008
Froyen, G., Corbett, M., Vandewalle, J., Jarvela, I., Lawrence, O., Meldrum, C., Bauters, M., Govaerts, K., Vandeleur, L., Van Esch, H., Chelly, J., Sanlaville, D., van Bokhoven, H., Ropers, H.-H., Laumonnier, F., Ranieri, E., Schwartz, C. E., Abidi, F., Tarpey, P. S., … Gécz, J. (2008). Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation. The American Journal of Human Genetics, 82(2), 432–443. https://doi.org/10.1016/j.ajhg.2007.11.002
Fine-Scale Survey of X Chromosome Copy Number Variants and Indels Underlying Intellectual Disability
The American Journal of Human Genetics / Aug 01, 2010
Whibley, A. C., Plagnol, V., Tarpey, P. S., Abidi, F., Fullston, T., Choma, M. K., Boucher, C. A., Shepherd, L., Willatt, L., Parkin, G., Smith, R., Futreal, P. A., Shaw, M., Boyle, J., Licata, A., Skinner, C., Stevenson, R. E., Turner, G., Field, M., … Raymond, F. L. (2010). Fine-Scale Survey of X Chromosome Copy Number Variants and Indels Underlying Intellectual Disability. The American Journal of Human Genetics, 87(2), 173–188. https://doi.org/10.1016/j.ajhg.2010.06.017
Genetic architecture and balancing selection: the life and death of differentiated variants
Molecular Ecology / Mar 06, 2017
Llaurens, V., Whibley, A., & Joron, M. (2017). Genetic architecture and balancing selection: the life and death of differentiated variants. Molecular Ecology, 26(9), 2430–2448. Portico. https://doi.org/10.1111/mec.14051
CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes
European Journal of Human Genetics / Dec 23, 2009
Hackett, A., Tarpey, P. S., Licata, A., Cox, J., Whibley, A., Boyle, J., Rogers, C., Grigg, J., Partington, M., Stevenson, R. E., Tolmie, J., Yates, J. R., Turner, G., Wilson, M., Futreal, A. P., Corbett, M., Shaw, M., Gecz, J., Raymond, F. L., … Abidi, F. E. (2009). CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes. European Journal of Human Genetics, 18(5), 544–552. https://doi.org/10.1038/ejhg.2009.220
Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms
Nature Genetics / Jan 25, 2021
Jay, P., Chouteau, M., Whibley, A., Bastide, H., Parrinello, H., Llaurens, V., & Joron, M. (2021). Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms. Nature Genetics, 53(3), 288–293. https://doi.org/10.1038/s41588-020-00771-1
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks
Human Molecular Genetics / Jan 11, 2010
Kerzendorfer, C., Whibley, A., Carpenter, G., Outwin, E., Chiang, S.-C., Turner, G., Schwartz, C., El-Khamisy, S., Raymond, F. L., & O’Driscoll, M. (2010). Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks. Human Molecular Genetics, 19(7), 1324–1334. https://doi.org/10.1093/hmg/ddq008
Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies
Heredity / Mar 25, 2015
Huber, B., Whibley, A., Poul, Y. L., Navarro, N., Martin, A., Baxter, S., Shah, A., Gilles, B., Wirth, T., McMillan, W. O., & Joron, M. (2015). Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity, 114(5), 515–524. https://doi.org/10.1038/hdy.2015.22
Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movements
European Journal of Human Genetics / May 19, 2010
Whibley, A., Urquhart, J., Dore, J., Willatt, L., Parkin, G., Gaunt, L., Black, G., Donnai, D., & Raymond, F. L. (2010). Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movements. European Journal of Human Genetics, 18(10), 1095–1099. https://doi.org/10.1038/ejhg.2010.41
Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads
Heredity / Oct 01, 2014
Gouin, A., Legeai, F., Nouhaud, P., Whibley, A., Simon, J.-C., & Lemaitre, C. (2014). Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads. Heredity, 114(5), 494–501. https://doi.org/10.1038/hdy.2014.85
The changing face of genome assemblies: Guidance on achieving high‐quality reference genomes
Molecular Ecology Resources / Jan 20, 2021
Whibley, A., Kelley, J. L., & Narum, S. R. (2021). The changing face of genome assemblies: Guidance on achieving high‐quality reference genomes. Molecular Ecology Resources, 21(3), 641–652. Portico. https://doi.org/10.1111/1755-0998.13312
Lessons learnt from large-scale exon re-sequencing of the X chromosome
Human Molecular Genetics / Apr 15, 2009
Raymond, F. L., Whibley, A., Stratton, M. R., & Gecz, J. (2009). Lessons learnt from large-scale exon re-sequencing of the X chromosome. Human Molecular Genetics, 18(R1), R60–R64. https://doi.org/10.1093/hmg/ddp071
WING SHAPE VARIATION ASSOCIATED WITH MIMICRY IN BUTTERFLIES
Evolution / Apr 24, 2013
Jones, R. T., Poul, Y. L., Whibley, A. C., Mérot, C., ffrench-Constant, R. H., & Joron, M. (2013). WING SHAPE VARIATION ASSOCIATED WITH MIMICRY IN BUTTERFLIES. Evolution, 67(8), 2323–2334. https://doi.org/10.1111/evo.12114
Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi
Molecular Ecology / Jul 26, 2021
Duntsch, L., Whibley, A., Brekke, P., Ewen, J. G., & Santure, A. W. (2021). Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi. Molecular Ecology, 30(23), 6006–6020. Portico. https://doi.org/10.1111/mec.16068
Sharing and reporting benefits from biodiversity research
Molecular Ecology / Nov 06, 2020
Marden, E., Abbott, R. J., Austerlitz, F., Ortiz‐Barrientos, D., Baucom, R. S., Bongaerts, P., Bonin, A., Bonneaud, C., Browne, L., Alex Buerkle, C., Caicedo, A. L., Coltman, D. W., Cruzan, M. B., Davison, A., DeWoody, J. A., Dumbrell, A. J., Emerson, B. C., Fountain‐Jones, N. M., Gillespie, R., … Rieseberg, L. H. (2020). Sharing and reporting benefits from biodiversity research. Molecular Ecology, 30(5), 1103–1107. Portico. https://doi.org/10.1111/mec.15702
Contrasting genomic and phenotypic outcomes of hybridization between pairs of mimetic butterfly taxa across a suture zone
Molecular Ecology / Apr 01, 2020
Gauthier, J., de Silva, D. L., Gompert, Z., Whibley, A., Houssin, C., Le Poul, Y., McClure, M., Lemaitre, C., Legeai, F., Mallet, J., & Elias, M. (2020). Contrasting genomic and phenotypic outcomes of hybridization between pairs of mimetic butterfly taxa across a suture zone. Molecular Ecology, 29(7), 1328–1343. Portico. https://doi.org/10.1111/mec.15403
Recurrent deletion ofZNF630at Xp11.23 is not associated with mental retardation
American Journal of Medical Genetics Part A / Mar 01, 2010
Lugtenberg, D., Zangrande-Vieira, L., Kirchhoff, M., Whibley, A. C., Oudakker, A. R., Kjaergaard, S., Vianna-Morgante, A. M., Kleefstra, T., Ruiter, M., Jehee, F. S., Ullmann, R., Schwartz, C. E., Stratton, M., Raymond, F. L., Veltman, J. A., Vrijenhoek, T., Pfundt, R., Schuurs-Hoeijmakers, J. H. M., Hehir-Kwa, J. Y., … de Brouwer, A. P. M. (2010). Recurrent deletion ofZNF630at Xp11.23 is not associated with mental retardation. American Journal of Medical Genetics Part A, 152A(3), 638–645. https://doi.org/10.1002/ajmg.a.33292
The design and application of a 50 K SNP chip for a threatened Aotearoa New Zealand passerine, the hihi
Molecular Ecology Resources / Aug 07, 2021
Lee, K. D., Millar, C. D., Brekke, P., Whibley, A., Ewen, J. G., Hingston, M., Zhu, A., & Santure, A. W. (2021). The design and application of a 50 K SNP chip for a threatened Aotearoa New Zealand passerine, the hihi. Molecular Ecology Resources, 22(1), 415–429. Portico. https://doi.org/10.1111/1755-0998.13480
Genomic signatures of inbreeding depression for a threatened Aotearoa New Zealand passerine
Molecular Ecology / Feb 05, 2023
Duntsch, L., Whibley, A., de Villemereuil, P., Brekke, P., Bailey, S., Ewen, J. G., & Santure, A. W. (2023). Genomic signatures of inbreeding depression for a threatened Aotearoa New Zealand passerine. Molecular Ecology, 32(8), 1893–1907. Portico. https://doi.org/10.1111/mec.16855
Assembly of female and male hihi genomes (stitchbird; Notiomystis cincta) enables characterization of the W chromosome and resources for conservation genomics
Molecular Ecology Resources / Jun 18, 2023
Bailey, S., Guhlin, J., Senanayake, D. S., Scherer, P., Brekke, P., Ewen, J. G., Santure, A. W., & Whibley, A. (2023). Assembly of female and male hihi genomes (stitchbird; Notiomystis cincta) enables characterization of the W chromosome and resources for conservation genomics. Molecular Ecology Resources. Portico. https://doi.org/10.1111/1755-0998.13823
Tracing the introduction of the invasive common myna using population genomics
Heredity / May 17, 2023
Atsawawaranunt, K., Ewart, K. M., Major, R. E., Johnson, R. N., Santure, A. W., & Whibley, A. (2023). Tracing the introduction of the invasive common myna using population genomics. Heredity, 131(1), 56–67. https://doi.org/10.1038/s41437-023-00621-w
MtING2 encodes an
ING domain
PHD finger protein which
affects Medicago growth, flowering,
global patterns of
H3K4me3 , and gene
expression
The Plant Journal / Oct 17, 2022
Jaudal, M., Mayo‐Smith, M., Poulet, A., Whibley, A., Peng, Y., Zhang, L., Thomson, G., Trimborn, L., Jacob, Y., van Wolfswinkel, J. C., Goldstone, D. C., Wen, J., Mysore, K. S., & Putterill, J. (2022). <scp>MtING2</scp> encodes an <scp>ING</scp> domain <scp>PHD</scp> finger protein which affects Medicago growth, flowering, global patterns of <scp>H3K4me3</scp>, and gene expression. The Plant Journal, 112(4), 1029–1050. Portico. https://doi.org/10.1111/tpj.15994
Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies
Molecular Biology and Evolution / Jul 01, 2023
Rougemont, Q., Huber, B., Martin, S. H., Whibley, A., Estrada, C., Solano, D., Orpet, R., McMillan, W. O., Frérot, B., & Joron, M. (2023). Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies. Molecular Biology and Evolution, 40(7). https://doi.org/10.1093/molbev/msad166
First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies
Molecular Ecology Resources / Jan 27, 2023
Gauthier, J., Meier, J., Legeai, F., McClure, M., Whibley, A., Bretaudeau, A., Boulain, H., Parrinello, H., Mugford, S. T., Durbin, R., Zhou, C., McCarthy, S., Wheat, C. W., Piron‐Prunier, F., Monsempes, C., François, M., Jay, P., Noûs, C., Persyn, E., … Elias, M. (2023). First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies. Molecular Ecology Resources, 23(4), 872–885. Portico. https://doi.org/10.1111/1755-0998.13749
Genome insights give cause for optimism in the ongoing battle to save the vaquita
Molecular Ecology Resources / Feb 22, 2021
Whibley, A. (2021). Genome insights give cause for optimism in the ongoing battle to save the vaquita. Molecular Ecology Resources, 21(4), 1005–1007. Portico. https://doi.org/10.1111/1755-0998.13345
Stripes, sex and sparrows: what processes underlie heteromorphic chromosome evolution?
Heredity / Aug 18, 2010
Joron, M., & Whibley, A. (2010). Stripes, sex and sparrows: what processes underlie heteromorphic chromosome evolution? Heredity, 106(4), 531–532. https://doi.org/10.1038/hdy.2010.106
Matheus Ferraz
PhD in computational chemistry, bioinformatician with experience in industry
Most Relevant Research Interests
Other Research Interests (35)
Most Relevant Publications (1+)
17 total publications
Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil
Microbiology Spectrum / Feb 23, 2022
Naveca, F. G., Nascimento, V., Souza, V., Corado, A. de L., Nascimento, F., Silva, G., Mejía, M. C., Brandão, M. J., Costa, Á., Duarte, D., Pessoa, K., Jesus, M., Gonçalves, L., Fernandes, C., Mattos, T., Abdalla, L., Santos, J. H., Martins, A., Chui, F. M., … Bello, G. (2022). Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil. Microbiology Spectrum, 10(1). https://doi.org/10.1128/spectrum.02366-21
Ernesto Lowy
Senior Bioinformatician specialised in Cancer Genomics
Most Relevant Research Interests
Other Research Interests (28)
Most Relevant Publications (4+)
67 total publications
VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases
Nucleic Acids Research / Dec 15, 2014
Giraldo-Calderón, G. I., Emrich, S. J., MacCallum, R. M., Maslen, G., Dialynas, E., Topalis, P., Ho, N., Gesing, S., Madey, G., Collins, F. H., & Lawson, D. (2014). VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases. Nucleic Acids Research, 43(D1), D707–D713. https://doi.org/10.1093/nar/gku1117
Ensembl Genomes 2016: more genomes, more complexity
Nucleic Acids Research / Nov 17, 2015
Kersey, P. J., Allen, J. E., Armean, I., Boddu, S., Bolt, B. J., Carvalho-Silva, D., Christensen, M., Davis, P., Falin, L. J., Grabmueller, C., Humphrey, J., Kerhornou, A., Khobova, J., Aranganathan, N. K., Langridge, N., Lowy, E., McDowall, M. D., Maheswari, U., Nuhn, M., … Staines, D. M. (2015). Ensembl Genomes 2016: more genomes, more complexity. Nucleic Acids Research, 44(D1), D574–D580. https://doi.org/10.1093/nar/gkv1209
HLA Genes in the Chuvashian Population from European Russia: Admixture of Central European and Mediterranean Populations
Human Biology / Jan 01, 2003
Arnaiz-Villena, A., Martinez-Laso, J., Moscoso, J., Livshits, G., Zamora, J., Gomez-Casado, E., Silvera-Redondo, C., Melvin, K., & Crawford, M. H. (2003). HLA Genes in the Chuvashian Population from European Russia: Admixture of Central European and Mediterranean Populations. Human Biology, 75(3), 375–392. https://doi.org/10.1353/hub.2003.0040
HLA molecular markers in Tuvinians: a population with both Oriental and Caucasoid characteristics
Annals of Human Genetics / May 01, 2001
MARTINEZ-LASO, J., SARTAKOVA, M., ALLENDE, L., KONENKOV, V., MOSCOSO, J., SILVERA-REDONDO, C., PACHO, A., TRAPAGA, J., GOMEZ-CASADO, E., & ARNAIZ-VILLENA, A. (2001). HLA molecular markers in Tuvinians: a population with both Oriental and Caucasoid characteristics. Annals of Human Genetics, 65(3), 245–261. https://doi.org/10.1046/j.1469-1809.2001.6530245.x
Niko Popitsch
Senior Bioinformatician, University of Vienna
Most Relevant Research Interests
Other Research Interests (14)
Most Relevant Publications (3+)
73 total publications
The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation
PLOS Pathogens / Sep 15, 2015
Drecktrah, D., Lybecker, M., Popitsch, N., Rescheneder, P., Hall, L. S., & Samuels, D. S. (2015). The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation. PLOS Pathogens, 11(9), e1005160. https://doi.org/10.1371/journal.ppat.1005160
Mutations inPIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies
Human Molecular Genetics / Aug 20, 2015
Ilkovski, B., Pagnamenta, A. T., O’Grady, G. L., Kinoshita, T., Howard, M. F., Lek, M., Thomas, B., Turner, A., Christodoulou, J., Sillence, D., Knight, S. J. L., Popitsch, N., Keays, D. A., Anzilotti, C., Goriely, A., Waddell, L. B., Brilot, F., North, K. N., Kanzawa, N., … Clarke, N. F. (2015). Mutations inPIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies. Human Molecular Genetics, 24(21), 6146–6159. https://doi.org/10.1093/hmg/ddv331
Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders
European Journal of Human Genetics / Mar 22, 2017
Pagnamenta, A. T., Murakami, Y., Taylor, J. M., Anzilotti, C., Howard, M. F., Miller, V., Johnson, D. S., Tadros, S., Mansour, S., Temple, I. K., Firth, R., Rosser, E., Harrison, R. E., Kerr, B., Popitsch, N., Kinoshita, T., Taylor, J. C., & Kini, U. (2017). Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders. European Journal of Human Genetics, 25(6), 669–679. https://doi.org/10.1038/ejhg.2017.32
John Joe
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Most Relevant Research Interests
Other Research Interests (72)
Most Relevant Publications (4+)
95 total publications
Sequence and characteristics or IS900, an insertion element identified in a human Crohn's disease isolate orMycobacterium paratuberculosis
Nucleic Acids Research / Jan 01, 1989
Green, E. P., Tizard, M. L. V., Moss, M. T., Thompson, J., Winterbourne, D. J., McFadden, J. J., & Hermon-Taylor, J. (1989). Sequence and characteristics or IS900, an insertion element identified in a human Crohn’s disease isolate orMycobacterium paratuberculosis. Nucleic Acids Research, 17(22), 9063–9073. https://doi.org/10.1093/nar/17.22.9063
13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation
PLoS Pathogens / Jul 21, 2011
Beste, D. J. V., Bonde, B., Hawkins, N., Ward, J. L., Beale, M. H., Noack, S., Nöh, K., Kruger, N. J., Ratcliffe, R. G., & McFadden, J. (2011). 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation. PLoS Pathogens, 7(7), e1002091. https://doi.org/10.1371/journal.ppat.1002091
Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis
PLoS Computational Biology / Jun 30, 2011
Bonde, B. K., Beste, D. J. V., Laing, E., Kierzek, A. M., & McFadden, J. (2011). Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis. PLoS Computational Biology, 7(6), e1002060. https://doi.org/10.1371/journal.pcbi.1002060
Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle
BMC Genomics / May 28, 2019
Mendum, T. A., Chandran, A., Williams, K., Vordermeier, H. M., Villarreal-Ramos, B., Wu, H., Singh, A., Smith, A. A., Butler, R. E., Prasad, A., Bharti, N., Banerjee, R., Kasibhatla, S. M., Bhatt, A., Stewart, G. R., & McFadden, J. (2019). Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle. BMC Genomics, 20(1). https://doi.org/10.1186/s12864-019-5791-1
Nicolas Collao
University of Ottawa
Most Relevant Research Interests
Other Research Interests (19)
Most Relevant Publications (1+)
12 total publications
Muscle injury induces a transient senescence‐like state that is required for myofiber growth during muscle regeneration
The FASEB Journal / Oct 03, 2022
Young, L. V., Wakelin, G., Cameron, A. W. R., Springer, S. A., Ross, J. P., Wolters, G., Murphy, J. P., Arsenault, M. G., Ng, S., Collao, N., De Lisio, M., Ljubicic, V., & Johnston, A. P. W. (2022). Muscle injury induces a transient senescence‐like state that is required for myofiber growth during muscle regeneration. The FASEB Journal, 36(11). Portico. https://doi.org/10.1096/fj.202200289rr
Nina Esaki
Most Relevant Research Interests
Other Research Interests (8)
Most Relevant Publications (1+)
2 total publications
Next Steps: Applying a Trauma-Informed Model to Create an Anti-Racist Organizational Culture
Behavioral Sciences / Feb 09, 2022
Esaki, N., Reddy, M., & Bishop, C. T. (2022). Next Steps: Applying a Trauma-Informed Model to Create an Anti-Racist Organizational Culture. Behavioral Sciences, 12(2), 41. https://doi.org/10.3390/bs12020041
Shruti Muralidhar
Neuroscientist and Science Communicator with interests in science policy
Most Relevant Research Interests
Other Research Interests (16)
Most Relevant Publications (1+)
9 total publications
BiasWatchIndia
Trends in Genetics / Apr 01, 2021
BiasWatchIndia. (2021). Trends in Genetics, 37(4), 295–296. https://doi.org/10.1016/j.tig.2020.11.009
Anna Koster
Most Relevant Research Interests
Other Research Interests (11)
Most Relevant Publications (1+)
4 total publications
Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating
PLOS Computational Biology / Mar 30, 2020
McKiernan, K. A., Koster, A. K., Maduke, M., & Pande, V. S. (2020). Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating. PLOS Computational Biology, 16(3), e1007530. https://doi.org/10.1371/journal.pcbi.1007530
Example genetics projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on genetics?
Genetic Testing for Personalized Medicine
A pharmaceutical company can collaborate with a genetics researcher to develop genetic tests that predict individual responses to medications. This can help optimize treatment plans and improve patient outcomes.
Crop Improvement through Genetic Engineering
An agricultural company can partner with a genetics expert to enhance crop traits through genetic engineering. This can lead to improved yields, disease resistance, and nutritional value.
Genomic Data Analysis for Precision Agriculture
A technology company can work with a genetics researcher to analyze genomic data and provide insights for precision agriculture. This can optimize resource allocation, improve crop management, and reduce environmental impact.
Genetic Counseling Services
A healthcare company can collaborate with a genetics specialist to offer genetic counseling services. This can help individuals understand their genetic risks, make informed decisions, and manage their health proactively.
Drug Discovery and Target Identification
A biotechnology company can partner with a genetics researcher to identify potential drug targets based on genetic insights. This can accelerate the discovery and development of novel therapeutics.