Work with academic experts in genetics
A scholar or researcher with expertise in genetics can help business and industrial clients solve their genetics problems and conduct genetics research to get ahead on R&D. Experts on NotedSource with backgrounds in genetics include Krista Kaasik, Giuliana Noratto, Francesc Lopez, Michael Paxhia, Sally Irwin, Artemis Louyakis, Jeffrey Townsend, Diane Imburgio, Diane Imburgio, Edoardo Airoldi, Peter Reich, Boris Leibovitch, Dona SLEIMAN, Michael W Harman, Jennifer Aaker, Dr. Susanne Ressl, Katelyn Katelyn Masiuk, John Joe, Anna Koster, Marina Baretti, Mehrdad Sheikhvatan, Daniel Milej, Ph.D., and Patrick G. Grant, Ph.D..
Giuliana Noratto
Food Scientist PhD and Registered Dietician - Texas A&M University
Most Relevant Research Interests
Other Research Interests (47)
About
Most Relevant Publications (23+)
91 total publications
Quinoa protective effects against obesity‐induced intestinal inflammation
The FASEB Journal / Apr 01, 2015
Noratto, G., Carrion‐Rabanal, R., Medina, G., Mencia, A., Mohanty, I., Gonzalez, D., & Murphy, K. (2015). Quinoa protective effects against obesity‐induced intestinal inflammation. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.602.9
Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells
The FASEB Journal / Mar 01, 2006
Mo, H., Noratto, G., Fernandes, N., Hussein, D., Sodhani, S., & Cisneros‐Zevallos, L. (2006). Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells. The FASEB Journal, 20(4). Portico. https://doi.org/10.1096/fasebj.20.4.a565-b
Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD)
The FASEB Journal / Apr 01, 2015
Ravisankar, S., Campos Gutierrez, D., Chirinos, R., & Noratto, G. (2015). Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD). The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.923.10
Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia
The FASEB Journal / Apr 01, 2013
Noratto, G., Condezo‐Hoyos, L., Gasco, M., & Gonzales, G. (2013). Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.861.25
Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice
The FASEB Journal / Apr 01, 2015
Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283
Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice
The FASEB Journal / Apr 01, 2015
Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283
Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5)
The FASEB Journal / Apr 01, 2014
Yuan, J., Noratto, K., Munske, G., Pilla, P., Mohanty, I., Alcantara Zapata, D., & Noratto, G. (2014). Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1018.5
Quinoa as source of bioactive compounds with potential for intestinal health (647.18)
The FASEB Journal / Apr 01, 2014
Carrion, R., Murphy, K., Ganjyal, G., Kowalski, R., & Noratto, G. (2014). Quinoa as source of bioactive compounds with potential for intestinal health (647.18). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.647.18
Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells
The FASEB Journal / Apr 01, 2009
Del Follo, A., Noratto, G. D., & Mertens‐Talcott, S. (2009). Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.4
Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells
The FASEB Journal / Apr 01, 2009
Townsley, E. D., Noratto, G., Angel, G., Del Follo, A., Byrne, D., & Mertens‐Talcott, S. (2009). Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.12
Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity
The FASEB Journal / Apr 01, 2015
yuan, jialing, chew, B., & noratto, giuliana. (2015). Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.276.7
Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice
The FASEB Journal / Apr 01, 2015
Noratto, G., García‐Pérez, E., Ivanov, I., & Mills, D. (2015). Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.385.5
The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3)
The FASEB Journal / Apr 01, 2014
Bibi, S., Balemba, O., Carrion‐Rabanal, R., Nyavor, Y., & Noratto, G. (2014). The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.259.3
Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk
The FASEB Journal / Apr 01, 2012
Noratto, G. D., Chirinos, R., Campos, D., Larondelle, Y., Arbizu, S., Dos Santos, M. M., & Mertens-Talcott, S. (2012). Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.626.13
Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target
The FASEB Journal / Apr 01, 2015
Ravisankar, S., & Noratto, G. (2015). Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.130.7
Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice
The FASEB Journal / Apr 01, 2015
Mohanty, I., yuan, J., Noratto, G., Balemba, O., & Morris, C. (2015). Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.254.3
Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12)
The FASEB Journal / Apr 01, 2014
Ravisankar, S., Yuan, J., Munske, G., & Noratto, G. (2014). Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1034.12
Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7)
The FASEB Journal / Apr 01, 2014
Noratto, G., Mohanty, I., Alcantara Zapata, D., & Chew, B. (2014). Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.249.7
Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes
The FASEB Journal / Apr 01, 2013
Martino, H., Noratto, G., Dias, M., Talcott, S., & Mertens‐Talcott, S. (2013). Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.865.5
Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats
The FASEB Journal / Apr 01, 2012
Noratto, G. D., Simbo, S., Martino, H. S., Byrne, D., & Mertens-Talcott, S. (2012). Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.364.3
Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a
The FASEB Journal / Apr 01, 2011
Noratto, G. D., Simbo, S. Y., Safe, S., & Mertens‐Talcott, S. U. (2011). Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a. The FASEB Journal, 25(S1). Portico. https://doi.org/10.1096/fasebj.25.1_supplement.213.4
Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC)
The FASEB Journal / Apr 01, 2010
Angel‐Morales, G., Noratto, G., & Mertens‐Talcott, S. (2010). Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC). The FASEB Journal, 24(S1). Portico. https://doi.org/10.1096/fasebj.24.1_supplement.924.5
Technical note: Optimization of lactose quantification based on coupled enzymatic reactions
Journal of Dairy Science / Apr 01, 2014
Condezo-Hoyos, L., Mohanty, I. P., & Noratto, G. D. (2014). Technical note: Optimization of lactose quantification based on coupled enzymatic reactions. Journal of Dairy Science, 97(4), 2066–2070. https://doi.org/10.3168/jds.2013-7436
Sally Irwin
Professor of Genetics and the Microbiome at the University of Hawaii
Most Relevant Research Interests
Other Research Interests (6)
Most Relevant Publications (1+)
3 total publications
Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce
Genome / Oct 01, 1999
Irwin, S. V., Kesseli, R. V., Waycott, W., Ryder, E. J., Cho, J. J., & Michelmore, R. W. (1999). Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce. Genome, 42(5), 982–986. https://doi.org/10.1139/g99-055
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
Most Relevant Research Interests
Other Research Interests (76)
About
Most Relevant Publications (64+)
207 total publications
The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits
Systematic Biology / Apr 01, 2009
Schoch, C. L., Sung, G.-H., López-Giráldez, F., Townsend, J. P., Miadlikowska, J., Hofstetter, V., Robbertse, B., Matheny, P. B., Kauff, F., Wang, Z., Gueidan, C., Andrie, R. M., Trippe, K., Ciufetti, L. M., Wynns, A., Fraker, E., Hodkinson, B. P., Bonito, G., Groenewald, J. Z., … Spatafora, J. W. (2009). The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits. Systematic Biology, 58(2), 224–239. https://doi.org/10.1093/sysbio/syp020
Profiling Phylogenetic Informativeness
Systematic Biology / Apr 01, 2007
Townsend, J. P. (2007). Profiling Phylogenetic Informativeness. Systematic Biology, 56(2), 222–231. https://doi.org/10.1080/10635150701311362
Phylogenetic and phylogenomic overview of the Polyporales
Mycologia / Nov 01, 2013
Binder, M., Justo, A., Riley, R., Salamov, A., Lopez-Giraldez, F., Sjökvist, E., Copeland, A., Foster, B., Sun, H., Larsson, E., Larsson, K.-H., Townsend, J., Grigoriev, I. V., & Hibbett, D. S. (2013). Phylogenetic and phylogenomic overview of the Polyporales. Mycologia, 105(6), 1350–1373. https://doi.org/10.3852/13-003
Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays
BMC Genomics / Oct 02, 2003
Townsend, J. P. (2003). Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays. BMC Genomics, 4(1). https://doi.org/10.1186/1471-2164-4-41
Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays
Gene / May 01, 2004
Lim, C. R., Fukakusa, A., & Matsubara, K. (2004). Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays. Gene, 333, 3–13. https://doi.org/10.1016/j.gene.2004.02.026
Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes
Genetics / May 01, 2003
Townsend, J. P., Nielsen, K. M., Fisher, D. S., & Hartl, D. L. (2003). Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes. Genetics, 164(1), 13–21. https://doi.org/10.1093/genetics/164.1.13
Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa
mSystems / Jun 28, 2022
Wang, Z., Lopez-Giraldez, F., Slot, J., Yarden, O., Trail, F., & Townsend, J. P. (2022). Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa. MSystems, 7(3). https://doi.org/10.1128/msystems.00232-22
Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes
Molecular Biology and Evolution / Apr 26, 2022
Cannataro, V. L., Mandell, J. D., & Townsend, J. P. (2022). Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes. Molecular Biology and Evolution, 39(5). https://doi.org/10.1093/molbev/msac084
Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales)
Microbiology Resource Announcements / Feb 17, 2022
Gortikov, M., Wang, Z., Steindorff, A. S., Grigoriev, I. V., Druzhinina, I. S., Townsend, J. P., & Yarden, O. (2022). Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales). Microbiology Resource Announcements, 11(2). https://doi.org/10.1128/mra.00995-21
Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy
PLOS Computational Biology / Jun 09, 2021
Wells, C. R., Cao, Y., Durham, D. P., Byrareddy, S. N., Ansari, A. A., Ruddle, N. H., Townsend, J. P., Galvani, A. P., & Perelson, A. S. (2021). Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy. PLOS Computational Biology, 17(6), e1009031. https://doi.org/10.1371/journal.pcbi.1009031
Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification
Genome Biology and Evolution / Nov 16, 2020
Dornburg, A., Wang, Z., Wang, J., Mo, E. S., López-Giráldez, F., & Townsend, J. P. (2020). Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification. Genome Biology and Evolution, 13(1). https://doi.org/10.1093/gbe/evaa228
Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi
Molecular Biology and Evolution / Mar 19, 2020
Merényi, Z., Prasanna, A. N., Wang, Z., Kovács, K., Hegedüs, B., Bálint, B., Papp, B., Townsend, J. P., & Nagy, L. G. (2020). Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi. Molecular Biology and Evolution, 37(8), 2228–2240. https://doi.org/10.1093/molbev/msaa077
Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model
Systematic Biology / Oct 29, 2019
Scott, J. G., Maini, P. K., Anderson, A. R. A., & Fletcher, A. G. (2019). Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model. Systematic Biology, 69(4), 623–637. https://doi.org/10.1093/sysbio/syz070
Molecular Biology and Evolution of Cancer: From Discovery to Action
Molecular Biology and Evolution / Oct 23, 2019
Somarelli, J. A., Gardner, H., Cannataro, V. L., Gunady, E. F., Boddy, A. M., Johnson, N. A., Fisk, J. N., Gaffney, S. G., Chuang, J. H., Li, S., Ciccarelli, F. D., Panchenko, A. R., Megquier, K., Kumar, S., Dornburg, A., DeGregori, J., & Townsend, J. P. (2019). Molecular Biology and Evolution of Cancer: From Discovery to Action. Molecular Biology and Evolution, 37(2), 320–326. https://doi.org/10.1093/molbev/msz242
Modelling microbial infection to address global health challenges
Nature Microbiology / Sep 20, 2019
Fitzpatrick, M. C., Bauch, C. T., Townsend, J. P., & Galvani, A. P. (2019). Modelling microbial infection to address global health challenges. Nature Microbiology, 4(10), 1612–1619. https://doi.org/10.1038/s41564-019-0565-8
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
Oncogene / Jan 15, 2019
Cannataro, V. L., Gaffney, S. G., Sasaki, T., Issaeva, N., Grewal, N. K. S., Grandis, J. R., Yarbrough, W. G., Burtness, B., Anderson, K. S., & Townsend, J. P. (2019). APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma. Oncogene, 38(18), 3475–3487. https://doi.org/10.1038/s41388-018-0657-6
Wagging the long tail of drivers of prostate cancer
PLOS Genetics / Jan 17, 2019
Cannataro, V. L., & Townsend, J. P. (2019). Wagging the long tail of drivers of prostate cancer. PLOS Genetics, 15(1), e1007820. https://doi.org/10.1371/journal.pgen.1007820
Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets
Systematic Biology / Jun 25, 2018
Dornburg, A., Su, Z., & Townsend, J. P. (2018). Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets. Systematic Biology, 68(1), 145–156. https://doi.org/10.1093/sysbio/syy047
Somatic evolutionary timings of driver mutations
BMC Cancer / Jan 18, 2018
Gomez, K., Miura, S., Huuki, L. A., Spell, B. S., Townsend, J. P., & Kumar, S. (2018). Somatic evolutionary timings of driver mutations. BMC Cancer, 18(1). https://doi.org/10.1186/s12885-017-3977-y
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution / Apr 19, 2018
Cannataro, V. L., & Townsend, J. P. (2018). Neutral Theory and the Somatic Evolution of Cancer. Molecular Biology and Evolution, 35(6), 1308–1315. https://doi.org/10.1093/molbev/msy079
Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C
Oncogene / Feb 16, 2018
Cannataro, V. L., Gaffney, S. G., Stender, C., Zhao, Z.-M., Philips, M., Greenstein, A. E., & Townsend, J. P. (2018). Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C. Oncogene, 37(18), 2444–2455. https://doi.org/10.1038/s41388-017-0105-z
Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues
Molecular Ecology / Dec 12, 2017
Wang, Z., Wang, J., Li, N., Li, J., Trail, F., Dunlap, J. C., & Townsend, J. P. (2017). Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues. Molecular Ecology, 27(1), 216–232. Portico. https://doi.org/10.1111/mec.14425
Neutral Theory and the Somatic Evolution of Cancer
Molecular Biology and Evolution / May 14, 2018
Neutral Theory and the Somatic Evolution of Cancer. (2018). Molecular Biology and Evolution, 35(6), 1561–1561. https://doi.org/10.1093/molbev/msy100
Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence
Molecular Biology and Evolution / Jul 28, 2017
Zhao, Z.-M., Campbell, M. C., Li, N., Lee, D. S. W., Zhang, Z., & Townsend, J. P. (2017). Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence. Molecular Biology and Evolution, 34(11), 3006–3022. https://doi.org/10.1093/molbev/msx213
Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana
Genetics / Aug 01, 2017
Park, B., Rutter, M. T., Fenster, C. B., Symonds, V. V., Ungerer, M. C., & Townsend, J. P. (2017). Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana. Genetics, 206(4), 2105–2117. https://doi.org/10.1534/genetics.116.199190
The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi
PLOS Genetics / Jul 13, 2017
Trail, F., Wang, Z., Stefanko, K., Cubba, C., & Townsend, J. P. (2017). The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi. PLOS Genetics, 13(7), e1006867. https://doi.org/10.1371/journal.pgen.1006867
New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset
Molecular Phylogenetics and Evolution / May 01, 2017
Dornburg, A., Townsend, J. P., Brooks, W., Spriggs, E., Eytan, R. I., Moore, J. A., Wainwright, P. C., Lemmon, A., Lemmon, E. M., & Near, T. J. (2017). New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset. Molecular Phylogenetics and Evolution, 110, 27–38. https://doi.org/10.1016/j.ympev.2017.02.017
PhyloOncology: Understanding cancer through phylogenetic analysis
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer / Apr 01, 2017
Somarelli, J. A., Ware, K. E., Kostadinov, R., Robinson, J. M., Amri, H., Abu-Asab, M., Fourie, N., Diogo, R., Swofford, D., & Townsend, J. P. (2017). PhyloOncology: Understanding cancer through phylogenetic analysis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1867(2), 101–108. https://doi.org/10.1016/j.bbcan.2016.10.006
A working model of the deep relationships of diverse modern human genetic lineages outside of Africa
Molecular Biology and Evolution / Jan 10, 2017
Lipson, M., & Reich, D. (2017). A working model of the deep relationships of diverse modern human genetic lineages outside of Africa. Molecular Biology and Evolution, msw293. https://doi.org/10.1093/molbev/msw293
Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification
Molecular Biology and Evolution / Jan 12, 2017
Wu, W. K. K., Li, X., Wang, X., Dai, R. Z. W., Cheng, A. S. L., Wang, M. H. T., Kwong, T., Chow, T. C., Yu, J., Chan, M. T. V., & Wong, S. H. (2017). Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification. Molecular Biology and Evolution, msw295. https://doi.org/10.1093/molbev/msw295
Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection
Molecular Biology and Evolution / Apr 20, 2015
Hodgins-Davis, A., Rice, D. P., & Townsend, J. P. (2015). Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection. Molecular Biology and Evolution, 32(8), 2130–2140. https://doi.org/10.1093/molbev/msv094
H-CLAP: hierarchical clustering within a linear array with an application in genetics
Statistical Applications in Genetics and Molecular Biology / Jan 01, 2015
Ghosh, S., & Townsend, J. P. (2015). H-CLAP: hierarchical clustering within a linear array with an application in genetics. Statistical Applications in Genetics and Molecular Biology, 14(2). https://doi.org/10.1515/sagmb-2013-0076
The peopling of the African continent and the diaspora into the new world
Current Opinion in Genetics & Development / Dec 01, 2014
Campbell, M. C., Hirbo, J. B., Townsend, J. P., & Tishkoff, S. A. (2014). The peopling of the African continent and the diaspora into the new world. Current Opinion in Genetics & Development, 29, 120–132. https://doi.org/10.1016/j.gde.2014.09.003
Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa
G3 Genes|Genomes|Genetics / Sep 01, 2014
Wu, C., Yang, F., Smith, K. M., Peterson, M., Dekhang, R., Zhang, Y., Zucker, J., Bredeweg, E. L., Mallappa, C., Zhou, X., Lyubetskaya, A., Townsend, J. P., Galagan, J. E., Freitag, M., Dunlap, J. C., Bell-Pedersen, D., & Sachs, M. S. (2014). Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa. G3 Genes|Genomes|Genetics, 4(9), 1731–1745. https://doi.org/10.1534/g3.114.012617
Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
PLoS Pathogens / May 08, 2014
Talbert-Slagle, K., Atkins, K. E., Yan, K.-K., Khurana, E., Gerstein, M., Bradley, E. H., Berg, D., Galvani, A. P., & Townsend, J. P. (2014). Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body. PLoS Pathogens, 10(5), e1004092. https://doi.org/10.1371/journal.ppat.1004092
Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design
Molecular Phylogenetics and Evolution / Jan 01, 2013
Moeller, A. H., & Townsend, J. P. (2013). Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design. Molecular Phylogenetics and Evolution, 66(1), 436. https://doi.org/10.1016/j.ympev.2012.09.035
Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny
Systematic Biology / Mar 03, 2012
Townsend, J. P., Su, Z., & Tekle, Y. I. (2012). Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny. Systematic Biology, 61(5), 835. https://doi.org/10.1093/sysbio/sys036
Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size
G3 Genes|Genomes|Genetics / Aug 01, 2012
Rice, D. P., & Townsend, J. P. (2012). Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size. G3 Genes|Genomes|Genetics, 2(8), 905–911. https://doi.org/10.1534/g3.112.003228
Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology
Fungal Genetics and Biology / Aug 01, 2012
Sikhakolli, U. R., López-Giráldez, F., Li, N., Common, R., Townsend, J. P., & Trail, F. (2012). Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology. Fungal Genetics and Biology, 49(8), 663–673. https://doi.org/10.1016/j.fgb.2012.05.009
Sex-specific gene expression during asexual development of Neurospora crassa
Fungal Genetics and Biology / Jul 01, 2012
Wang, Z., Kin, K., López-Giráldez, F., Johannesson, H., & Townsend, J. P. (2012). Sex-specific gene expression during asexual development of Neurospora crassa. Fungal Genetics and Biology, 49(7), 533–543. https://doi.org/10.1016/j.fgb.2012.05.004
Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa
Fungal Genetics and Biology / May 01, 2012
Wang, Z., Lehr, N., Trail, F., & Townsend, J. P. (2012). Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa. Fungal Genetics and Biology, 49(5), 405–413. https://doi.org/10.1016/j.fgb.2012.03.004
A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data
Genetics / Apr 01, 2012
Rice, D. P., & Townsend, J. P. (2012). A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data. Genetics, 190(4), 1533–1545. https://doi.org/10.1534/genetics.111.137075
Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae
Genome Biology and Evolution / Jan 01, 2012
Hodgins-Davis, A., Adomas, A. B., Warringer, J., & Townsend, J. P. (2012). Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae. Genome Biology and Evolution, 4(11), 1061–1079. https://doi.org/10.1093/gbe/evs084
Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates
Molecular Phylogenetics and Evolution / Aug 01, 2011
Moeller, A. H., & Townsend, J. P. (2011). Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates. Molecular Phylogenetics and Evolution, 60(2), 271–272. https://doi.org/10.1016/j.ympev.2011.04.023
Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference
Systematic Biology / Feb 08, 2011
Townsend, J. P., & Leuenberger, C. (2011). Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference. Systematic Biology, 60(3), 358–365. https://doi.org/10.1093/sysbio/syq097
Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny
Mycologia / Sep 01, 2010
Ohenoja, E., Wang, Z., Townsend, J. P., Mitchel, D., & Voitk, A. (2010). Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny. Mycologia, 102(5), 1089–1095. https://doi.org/10.3852/09-317
Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships
Systematic Biology / May 19, 2010
Townsend, J. P., & Lopez-Giraldez, F. (2010). Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships. Systematic Biology, 59(4), 446–457. https://doi.org/10.1093/sysbio/syq025
Identification of new molecular markers for assembling the eukaryotic tree of life
Molecular Phylogenetics and Evolution / Jun 01, 2010
Tekle, Y. I., Grant, J. R., Kovner, A. M., Townsend, J. P., & Katz, L. A. (2010). Identification of new molecular markers for assembling the eukaryotic tree of life. Molecular Phylogenetics and Evolution, 55(3), 1177–1182. https://doi.org/10.1016/j.ympev.2010.03.010
The filamentous fungal gene expression database (FFGED)
Fungal Genetics and Biology / Mar 01, 2010
Zhang, Z., & Townsend, J. P. (2010). The filamentous fungal gene expression database (FFGED). Fungal Genetics and Biology, 47(3), 199–204. https://doi.org/10.1016/j.fgb.2009.12.001
Multi-targeted priming for genome-wide gene expression assays
BMC Genomics / Aug 17, 2010
Adomas, A. B., Lopez-Giraldez, F., Clark, T. A., Wang, Z., & Townsend, J. P. (2010). Multi-targeted priming for genome-wide gene expression assays. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-477
Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences
PLoS Computational Biology / Jun 26, 2009
Zhang, Z., & Townsend, J. P. (2009). Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences. PLoS Computational Biology, 5(6), e1000421. https://doi.org/10.1371/journal.pcbi.1000421
Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies
Genome Biology and Evolution / Jan 01, 2009
Otto, W., Stadler, P. F., López-Giraldéz, F., Townsend, J. P., Lynch, V. J., & Wagner, G. P. (2009). Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies. Genome Biology and Evolution, 1, 85–98. https://doi.org/10.1093/gbe/evp010
Article Commentary: Snapshots of Tree Space
Evolutionary Bioinformatics / Jan 01, 2009
Wang, Z., López-Giréidez, F., & Townsend, J. P. (2009). Article Commentary: Snapshots of Tree Space. Evolutionary Bioinformatics, 5, EBO.S3416. https://doi.org/10.4137/ebo.s3416
The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree
Journal of Molecular Evolution / Aug 12, 2008
Townsend, J. P., López-Giráldez, F., & Friedman, R. (2008). The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree. Journal of Molecular Evolution, 67(5), 437–447. https://doi.org/10.1007/s00239-008-9142-0
Sleuthing the difference a nucleotide can make
Molecular Ecology / Jun 01, 2008
TOWNSEND, J. P. (2008). Sleuthing the difference a nucleotide can make. Molecular Ecology, 17(12), 2793–2795. https://doi.org/10.1111/j.1365-294x.2008.03824.x
Quantifying variation in gene expression
Molecular Ecology / Jul 01, 2007
CLARK, T. A., & TOWNSEND, J. P. (2007). Quantifying variation in gene expression. Molecular Ecology, 16(13), 2613–2616. https://doi.org/10.1111/j.1365-294x.2007.03354.x
Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii
Fungal Genetics and Biology / Aug 01, 2006
Johannesson, H., Kasuga, T., Schaller, R. A., Good, B., Gardner, M. J., Townsend, J. P., Cole, G. T., & Taylor, J. W. (2006). Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii. Fungal Genetics and Biology, 43(8), 545–559. https://doi.org/10.1016/j.fgb.2006.02.003
Ecological and evolutionary genomics of Saccharomyces cerevisiae
Molecular Ecology / Feb 23, 2006
LANDRY, C. R., TOWNSEND, J. P., HARTL, D. L., & CAVALIERI, D. (2006). Ecological and evolutionary genomics of Saccharomyces cerevisiae. Molecular Ecology, 15(3), 575–591. https://doi.org/10.1111/j.1365-294x.2006.02778.x
Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination
Nucleic Acids Research / Nov 27, 2005
Kasuga, T. (2005). Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination. Nucleic Acids Research, 33(20), 6469–6485. https://doi.org/10.1093/nar/gki953
Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii
Genetics / Sep 01, 2005
Johannesson, H., Townsend, J. P., Hung, C.-Y., Cole, G. T., & Taylor, J. W. (2005). Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii. Genetics, 171(1), 109–117. https://doi.org/10.1534/genetics.105.040923
Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster
Heredity / May 12, 2004
Townsend, J. P., & Rand, D. M. (2004). Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster. Heredity, 93(1), 98–103. https://doi.org/10.1038/sj.hdy.6800484
Population Genetic Variation in Genome-Wide Gene Expression
Molecular Biology and Evolution / Apr 25, 2003
Townsend, J. P. (2003). Population Genetic Variation in Genome-Wide Gene Expression. Molecular Biology and Evolution, 20(6), 955–963. https://doi.org/10.1093/molbev/msg106
Pathway Processor: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks
Genome Research / Jul 01, 2002
Grosu, P., Townsend, J. P., Hartl, D. L., & Cavalieri, D. (2002). <tt>Pathway Processor</tt>: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks. Genome Research, 12(7), 1121–1126. https://doi.org/10.1101/gr.226602
Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica
Molecular Biology and Evolution / Feb 01, 2000
Bustamante, C. D., Townsend, J. P., & Hartl, D. L. (2000). Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica. Molecular Biology and Evolution, 17(2), 301–308. https://doi.org/10.1093/oxfordjournals.molbev.a026310
Edoardo Airoldi
Professor of Statistics & Data Science Temple University & PI, Harvard University
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Most Relevant Publications (6+)
106 total publications
Post-transcriptional regulation across human tissues
PLOS Computational Biology / May 08, 2017
Franks, A., Airoldi, E., & Slavov, N. (2017). Post-transcriptional regulation across human tissues. PLOS Computational Biology, 13(5), e1005535. https://doi.org/10.1371/journal.pcbi.1005535
Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data
Molecular Biology and Evolution / Mar 14, 2013
Wallace, E. W. J., Airoldi, E. M., & Drummond, D. A. (2013). Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data. Molecular Biology and Evolution, 30(6), 1438–1453. https://doi.org/10.1093/molbev/mst051
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells
PLoS Computational Biology / Dec 16, 2010
Markowetz, F., Mulder, K. W., Airoldi, E. M., Lemischka, I. R., & Troyanskaya, O. G. (2010). Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells. PLoS Computational Biology, 6(12), e1001034. https://doi.org/10.1371/journal.pcbi.1001034
Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
PLOS Genetics / May 07, 2015
Csárdi, G., Franks, A., Choi, D. S., Airoldi, E. M., & Drummond, D. A. (2015). Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast. PLOS Genetics, 11(5), e1005206. https://doi.org/10.1371/journal.pgen.1005206
Predicting Cellular Growth from Gene Expression Signatures
PLoS Computational Biology / Jan 02, 2009
Airoldi, E. M., Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., & Troyanskaya, O. G. (2009). Predicting Cellular Growth from Gene Expression Signatures. PLoS Computational Biology, 5(1), e1000257. https://doi.org/10.1371/journal.pcbi.1000257
Getting Started in Probabilistic Graphical Models
PLoS Computational Biology / Dec 07, 2007
Airoldi, E. M. (2007). Getting Started in Probabilistic Graphical Models. PLoS Computational Biology, 3(12), e252. https://doi.org/10.1371/journal.pcbi.0030252
Peter Reich
Director of the Institute for Global Change Biology (IGCB)
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509 total publications
Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment
Molecular Ecology / Jul 29, 2016
Nguyen, N. H., Williams, L. J., Vincent, J. B., Stefanski, A., Cavender-Bares, J., Messier, C., Paquette, A., Gravel, D., Reich, P. B., & Kennedy, P. G. (2016). Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment. Molecular Ecology, 25(16), 4032–4046. Portico. https://doi.org/10.1111/mec.13719
Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output
American Journal of Botany / Oct 01, 2015
Jacques, M.-H., Lapointe, L., Rice, K., Montgomery, R. A., Stefanski, A., & Reich, P. B. (2015). Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output. American Journal of Botany, 102(10), 1610–1624. Portico. https://doi.org/10.3732/ajb.1500046
Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities
Mycologia / Jul 01, 2009
Dickie, I. A., Dentinger, B. T. M., Avis, P. G., McLaughlin, D. J., & Reich, P. B. (2009). Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities. Mycologia, 101(4), 473–483. https://doi.org/10.3852/08-178
Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen
Physiologia Plantarum / Aug 01, 1996
Volin, J. C., & Reich, P. B. (1996). Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen. Physiologia Plantarum, 97(4), 674–684. https://doi.org/10.1034/j.1399-3054.1996.970407.x
Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings
Physiologia Plantarum / Dec 01, 1993
Kruger, E. L., & Reich, P. B. (1993). Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings. Physiologia Plantarum, 89(4), 751–760. https://doi.org/10.1111/j.1399-3054.1993.tb05281.x
Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean
Physiologia Plantarum / Jan 01, 1985
Reich, P. B., Schoettle, A. W., & Amundson, R. G. (1985). Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean. Physiologia Plantarum, 63(1), 58–64. https://doi.org/10.1111/j.1399-3054.1985.tb02818.x
Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark
Physiologia Plantarum / Aug 01, 1984
Reich, P. B. (1984). Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark. Physiologia Plantarum, 61(4), 541–548. https://doi.org/10.1111/j.1399-3054.1984.tb05167.x
Boris Leibovitch
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
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22 total publications
Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster
Cold Spring Harbor Symposia on Quantitative Biology / Jan 01, 2004
HAYNES, K. A., LEIBOVITCH, B. A., RANGWALA, S. H., CRAIG, C., & ELGIN, S. C. R. (2004). Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia on Quantitative Biology, 69(0), 267–272. https://doi.org/10.1101/sqb.2004.69.267
A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene
Genetical Research / Aug 01, 2001
GRANOK, H., LEIBOVITCH, B. A., & ELGIN, S. C. R. (2001). A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene. Genetical Research, 78(1), 13–21. https://doi.org/10.1017/s0016672301005122
Chromatin organization and transcriptional control of gene expression in Drosophila
Gene / Aug 01, 2000
Farkas, G., Leibovitch, B. A., & Elgin, S. C. R. (2000). Chromatin organization and transcriptional control of gene expression in Drosophila. Gene, 253(2), 117–136. https://doi.org/10.1016/s0378-1119(00)00240-7
Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics
Journal of Neurogenetics / Jan 01, 1995
Leibovitch, B. A., Campbell, D. B., Krishnan, K. S., & Nash, H. A. (1995). Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics. Journal of Neurogenetics, 10(1), 1–13. https://doi.org/10.3109/01677069509083455
Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae
Molecular and General Genetics MGG / Nov 01, 1984
Danilevskaya, O. N., Kurenova, E. V., Leibovitch, B. A., Shevelev, A. Ya., Bass, I. A., & Khesin, R. B. (1984). Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae. Molecular and General Genetics MGG, 197(2), 342–344. https://doi.org/10.1007/bf00330983
Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster
Molecular and General Genetics MGG / Jul 01, 1980
Chernyshev, A. I., Bashkirov, V. N., Leibovitch, B. A., & Khesin, R. B. (1980). Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster. Molecular and General Genetics MGG, 178(3), 663–668. https://doi.org/10.1007/bf00337876
Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster
Molecular and General Genetics MGG / Jan 01, 1978
Khesin, R. B., & Leibovitch, B. A. (1978). Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster. Molecular and General Genetics MGG, 162(3), 323–328. https://doi.org/10.1007/bf00268858
Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila
Chromosoma / Jan 01, 1976
Leibovitch, B. A., Belyaeva, E. S., Zhimulev, I. F., & Khesin, R. B. (1976). Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila. Chromosoma, 54(4), 349–362. https://doi.org/10.1007/bf00292815
Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster
Chromosoma / Jan 01, 1974
Khesin, R. B., & Leibovitch, B. A. (1974). Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster. Chromosoma, 46(2), 161–172. https://doi.org/10.1007/bf00332514
Dona SLEIMAN
After completing my BS in Biochemistry in Beirut, I pursued a master’s degree in Genetics followed by a Master 2 degree in Molecular Engineering. I received my PhD in Biochemistry and Biophysics in 2013 at Paris Descartes University with the highest honors & Committee Praise. Throughout my thesis and post-doctoral experience, I have studied different aspects of protein/nucleic acid interactions using several biophysical techniques.
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Most Relevant Publications (1+)
4 total publications
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus
PLOS Genetics / Apr 16, 2018
Devaux, L., Sleiman, D., Mazzuoli, M.-V., Gominet, M., Lanotte, P., Trieu-Cuot, P., Kaminski, P.-A., & Firon, A. (2018). Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus. PLOS Genetics, 14(4), e1007342. https://doi.org/10.1371/journal.pgen.1007342
Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
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15 total publications
The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ
Genes & Cancer / Dec 24, 2017
Gomes, C. J., Centuori, S. M., Harman, M. W., Putnam, C. W., Wolgemuth, C. W., & Martinez, J. D. (2017). The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ. Genes & Cancer, 8(11–12), 771–783. https://doi.org/10.18632/genesandcancer.161
Vinculin in Neutrophil Adhesion, Motility and Trafficking
The FASEB Journal / Apr 01, 2018
Wilson, Z., Harman, M., Hazlett, L., Odzer, J., Witt, H., Franck, C., Reichner, J., & Lefort, C. (2018). Vinculin in Neutrophil Adhesion, Motility and Trafficking. The FASEB Journal, 32(S1). Portico. https://doi.org/10.1096/fasebj.2018.32.1_supplement.280.11
Jennifer Aaker
General Atlantic Professor, Stanford University
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79 total publications
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG
Advances in Enzyme Regulation / Jan 01, 2002
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG. (2002). Advances in Enzyme Regulation, 42, EX17. https://doi.org/10.1016/s0065-2571(01)00055-3
Dr. Susanne Ressl
Biochemist & Structural Biologist | Project & Team Leader | Creative & Translational Thinker | Problem Solver | Mentor | Educator | Consultant | Innovator | Science Communicator & Writer | Relationship Builder | Collaborator
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Most Relevant Publications (2+)
20 total publications
Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila
G3 Genes|Genomes|Genetics / Dec 01, 2020
Song, W., Ressl, S., & Tracey, W. D. (2020). Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila. G3 Genes|Genomes|Genetics, 10(12), 4425–4438. https://doi.org/10.1534/g3.120.401767
C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins
The FASEB Journal / Dec 18, 2020
Sticco, M. J., Peña Palomino, P. A., Lukacsovich, D., Thompson, B. L., Földy, C., Ressl, S., & Martinelli, D. C. (2020). C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins. The FASEB Journal, 35(1). Portico. https://doi.org/10.1096/fj.202000351rr
Katelyn Katelyn Masiuk
Co-Founder and CSO at Immunovec
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13 total publications
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates
Molecular Therapy / Aug 01, 2019
Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome
Cell Stem Cell / Feb 01, 2019
Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003
PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector
Molecular Therapy - Methods & Clinical Development / Jun 01, 2019
Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods & Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005
Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells
Molecular Therapy / Sep 01, 2017
Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023
Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study
Human Gene Therapy / Oct 01, 2018
Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061
John Joe
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
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95 total publications
Sequence and characteristics or IS900, an insertion element identified in a human Crohn's disease isolate orMycobacterium paratuberculosis
Nucleic Acids Research / Jan 01, 1989
Green, E. P., Tizard, M. L. V., Moss, M. T., Thompson, J., Winterbourne, D. J., McFadden, J. J., & Hermon-Taylor, J. (1989). Sequence and characteristics or IS900, an insertion element identified in a human Crohn’s disease isolate orMycobacterium paratuberculosis. Nucleic Acids Research, 17(22), 9063–9073. https://doi.org/10.1093/nar/17.22.9063
13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation
PLoS Pathogens / Jul 21, 2011
Beste, D. J. V., Bonde, B., Hawkins, N., Ward, J. L., Beale, M. H., Noack, S., Nöh, K., Kruger, N. J., Ratcliffe, R. G., & McFadden, J. (2011). 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation. PLoS Pathogens, 7(7), e1002091. https://doi.org/10.1371/journal.ppat.1002091
Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis
PLoS Computational Biology / Jun 30, 2011
Bonde, B. K., Beste, D. J. V., Laing, E., Kierzek, A. M., & McFadden, J. (2011). Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis. PLoS Computational Biology, 7(6), e1002060. https://doi.org/10.1371/journal.pcbi.1002060
Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle
BMC Genomics / May 28, 2019
Mendum, T. A., Chandran, A., Williams, K., Vordermeier, H. M., Villarreal-Ramos, B., Wu, H., Singh, A., Smith, A. A., Butler, R. E., Prasad, A., Bharti, N., Banerjee, R., Kasibhatla, S. M., Bhatt, A., Stewart, G. R., & McFadden, J. (2019). Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle. BMC Genomics, 20(1). https://doi.org/10.1186/s12864-019-5791-1
Anna Koster
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4 total publications
Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating
PLOS Computational Biology / Mar 30, 2020
McKiernan, K. A., Koster, A. K., Maduke, M., & Pande, V. S. (2020). Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating. PLOS Computational Biology, 16(3), e1007530. https://doi.org/10.1371/journal.pcbi.1007530
Marina Baretti
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
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57 total publications
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence
Clinical Epigenetics / Dec 01, 2022
Heumann, T. R., Baretti, M., Sugar, E. A., Durham, J. N., Linden, S., Lopez-Vidal, T. Y., Leatherman, J., Cope, L., Sharma, A., Weekes, C. D., O’Dwyer, P. J., Reiss, K. A., Monga, D. K., Ahuja, N., & Azad, N. S. (2022). A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence. Clinical Epigenetics, 14(1). https://doi.org/10.1186/s13148-022-01367-8
Mehrdad Sheikhvatan
Iran University of Medical Sciences
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90 total publications
Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease
Iranian Journal of Biotechnology / Jun 01, 2019
Sheikhvatan, M., boroumand, M. A., Behmanesh, M., Ziaee, S., & Cheraghee, S. (2019). Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease. Iranian Journal of Biotechnology, 17(2), 79–88. https://doi.org/10.21859/ijb.1921
Daniel Milej, Ph.D.
Ph.D. in biomedical engineering
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91 total publications
Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions
The FASEB Journal / May 01, 2022
Shoemaker, L., Suwalski, M., Milej, D., Shoemaker, J. K., Chui, J., & St. Lawrence, K. (2022). Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3459
Patrick G. Grant, Ph.D.
Multi Discipline Experience with Multiple Open Inovation Solutions
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Most Relevant Publications (2+)
41 total publications
Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2
Molecular Reproduction and Development / Jan 01, 2000
Bench, G., Corzett, M. H., Kramer, C. E., Grant, P. G., & Balhorn, R. (2000). Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2. Molecular Reproduction and Development, 56(4), 512–519. https://doi.org/10.1002/1098-2795(200008)56:4<512::aid-mrd9>3.0.co;2-m
Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae)
American Journal of Botany / Oct 01, 2001
Clark, B. M., St. Clair, L. L., Mangelson, N. F., Rees, L. B., Grant, P. G., & Bench, G. S. (2001). Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae). American Journal of Botany, 88(10), 1742–1749. Portico. https://doi.org/10.2307/3558348