Work with thought leaders and academic experts in genetics

Companies can benefit from working with someone whose expertise is in the field of genetics in several ways. Firstly, they can enhance their research and development efforts by leveraging the academic researcher's knowledge and insights. The researcher can provide valuable guidance in designing experiments, analyzing data, and interpreting results. Secondly, companies can tap into the researcher's expertise to develop innovative products and solutions. The researcher's deep understanding of genetics can help identify new opportunities and create cutting-edge technologies. Thirdly, collaborating with an academic researcher can enhance a company's credibility and reputation. By partnering with a recognized expert in the field, companies can demonstrate their commitment to scientific excellence and gain trust from customers and investors. Lastly, the researcher can also contribute to the company's thought leadership and industry influence. Their research findings and publications can position the company as a leader in the genetics field and attract attention from key stakeholders.

Experts on NotedSource with backgrounds in genetics include Boris Leibovitch, Michael W Harman, Daniel Milej, Ph.D., Regan Hamel, Jeffrey Townsend, Edoardo Airoldi, Giuliana Noratto, Jennifer Aaker, Ping Luo, Ariel Aptekmann, Marina Baretti, Peter Reich, Katelyn Katelyn Masiuk, Asst. Prof. Eng. Davide Verzotto, Ph.D., Kayvan Najarian, Michael Paxhia, Artemis Louyakis, Dona SLEIMAN, Matthew Laye, Ph.D., JOAQUIN GADEA, Dr. Susanne Ressl, Andrew Mikhail, Paul Schrater, Olivier Saulnier, Gianfranco Santovito, Christine Wong, Ph.D., Sally Irwin, Mehrdad Sheikhvatan, Patrick G. Grant, Ph.D., Patrick Reeson, Chai Jin Lee, Annabel Whibley, Matheus Ferraz, Ernesto Lowy, Niko Popitsch, John Joe, Nicolas Collao, Nina Esaki, Shruti Muralidhar, William Gartner, Krista Kaasik, Francesc Lopez, Diane Imburgio, Anna Koster, and Diane Imburgio.

Boris Leibovitch

New York, New York, United States of America
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
Most Relevant Research Interests
Genetics
Other Research Interests (11)
Cancer Research
Cell Biology
Developmental Biology
Molecular Biology
Multidisciplinary
And 6 more
About
I am experienced molecular and cell biologist with deep genetics background who worked many years in USA and Russia on the bench and as teacher. Both types of work had demanded extremely broad knowledge and understanding of developments in the fields. Participation in grant writing, editorial/reviewer work for scientific journals and consulting colleagues on these subjects added a lot to my broad experience as the scientist.
Most Relevant Publications (9+)

22 total publications

Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster

Cold Spring Harbor Symposia on Quantitative Biology / Jan 01, 2004

HAYNES, K. A., LEIBOVITCH, B. A., RANGWALA, S. H., CRAIG, C., & ELGIN, S. C. R. (2004). Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila melanogaster. Cold Spring Harbor Symposia on Quantitative Biology, 69(0), 267–272. https://doi.org/10.1101/sqb.2004.69.267

A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene

Genetical Research / Aug 01, 2001

GRANOK, H., LEIBOVITCH, B. A., & ELGIN, S. C. R. (2001). A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene. Genetical Research, 78(1), 13–21. https://doi.org/10.1017/s0016672301005122

Chromatin organization and transcriptional control of gene expression in Drosophila

Gene / Aug 01, 2000

Farkas, G., Leibovitch, B. A., & Elgin, S. C. R. (2000). Chromatin organization and transcriptional control of gene expression in Drosophila. Gene, 253(2), 117–136. https://doi.org/10.1016/s0378-1119(00)00240-7

Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics

Journal of Neurogenetics / Jan 01, 1995

Leibovitch, B. A., Campbell, D. B., Krishnan, K. S., & Nash, H. A. (1995). Mutations That Affect Ion Channels Change the Sensitivity ofDrosophila Melanogasterto Volatile Anesthetics. Journal of Neurogenetics, 10(1), 1–13. https://doi.org/10.3109/01677069509083455

Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae

Molecular and General Genetics MGG / Nov 01, 1984

Danilevskaya, O. N., Kurenova, E. V., Leibovitch, B. A., Shevelev, A. Ya., Bass, I. A., & Khesin, R. B. (1984). Telomeres and P-element of Drosophila melanogaster contain sequences that replicate autonomously in Saccharomyces cerevisiae. Molecular and General Genetics MGG, 197(2), 342–344. https://doi.org/10.1007/bf00330983

Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster

Molecular and General Genetics MGG / Jul 01, 1980

Chernyshev, A. I., Bashkirov, V. N., Leibovitch, B. A., & Khesin, R. B. (1980). Increase in the number of histone genes in case of their deficiency in Drosophila melanogaster. Molecular and General Genetics MGG, 178(3), 663–668. https://doi.org/10.1007/bf00337876

Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster

Molecular and General Genetics MGG / Jan 01, 1978

Khesin, R. B., & Leibovitch, B. A. (1978). Influence of deficiency of the histone gene-containing 38B-40 region on X-chromosome template activity and the White gene position effect variegation in Drosophila melanogaster. Molecular and General Genetics MGG, 162(3), 323–328. https://doi.org/10.1007/bf00268858

Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila

Chromosoma / Jan 01, 1976

Leibovitch, B. A., Belyaeva, E. S., Zhimulev, I. F., & Khesin, R. B. (1976). Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila. Chromosoma, 54(4), 349–362. https://doi.org/10.1007/bf00292815

Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster

Chromosoma / Jan 01, 1974

Khesin, R. B., & Leibovitch, B. A. (1974). Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster. Chromosoma, 46(2), 161–172. https://doi.org/10.1007/bf00332514

Michael W Harman

East Greenwich, RI, Rhode Island, United States of America
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Interests
Genetics
Other Research Interests (16)
Bacteria & Cell Bio-Physics
Biomechanics
Infectious Diseases
Immunology
Microbiology
And 11 more
About
Highly skilled, energetic, and motivated professional empowered by over a decade of cross-disciplinary engineering and scientific applications experience. Presenting elegant solutions to prevalent biomedical challenges. Motivated by driving deliverable outcomes from complex research studies through effective leadership, active consulting work, and innovative problem-solving techniques. Seeking to make an immediate impact in a fast-paced biotechnology environment capitalizing on my advanced comprehension, continued professional growth, strategic product development expertise, and active network of personal connections across all areas of science, engineering, medicine, manufacturing and healthcare.
Most Relevant Publications (2+)

15 total publications

The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ

Genes & Cancer / Dec 24, 2017

Gomes, C. J., Centuori, S. M., Harman, M. W., Putnam, C. W., Wolgemuth, C. W., & Martinez, J. D. (2017). The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ. Genes & Cancer, 8(11–12), 771–783. https://doi.org/10.18632/genesandcancer.161

Vinculin in Neutrophil Adhesion, Motility and Trafficking

The FASEB Journal / Apr 01, 2018

Wilson, Z., Harman, M., Hazlett, L., Odzer, J., Witt, H., Franck, C., Reichner, J., & Lefort, C. (2018). Vinculin in Neutrophil Adhesion, Motility and Trafficking. The FASEB Journal, 32(S1). Portico. https://doi.org/10.1096/fasebj.2018.32.1_supplement.280.11

Daniel Milej, Ph.D.

London, Ontario, Canada
Ph.D. in biomedical engineering
Most Relevant Research Interests
Genetics
Other Research Interests (40)
Biomedical Optics
NIRS
fNIRS
Diffuse Correlation Spectroscopy
CBF
And 35 more
About
Dr. Daniel Milej is a multidisciplinary researcher with experience in medical biophysics, electronics, biocybernetics, biomedical optics and engineering. He is highly knowledgeable and experienced in a range of research techniques. He is currently a Research Associate at the Lawson Health Research Institute, leading the transition of multimodal optical imaging systems from a research setting to clinical use in an ICU and OR environment, working closely with teams of nurses, surgeons, doctors and respiratory therapists. Previously he was a postdoctoral fellow working on developing noninvasive modalities for brain activity monitoring in the Department of Medical Biophysics at Western University. Before that, Dr. Milej worked as a researcher at the Nalecz Institute of Biocybernetics and Biomedical Engineering. He obtained his Ph.D. in 2014 from the Polish Academy of Science, specializing in Electronics and Biomedical Engineering. He received his MSc from the Military University of Technology in 2008.
Most Relevant Publications (1+)

91 total publications

Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions

The FASEB Journal / May 01, 2022

Shoemaker, L., Suwalski, M., Milej, D., Shoemaker, J. K., Chui, J., & St. Lawrence, K. (2022). Assessment by Multi‐Distance Hyperspectral NIRS of Changes in the Oxidation State of Cytochrome C Oxidase (oxCCO) to Carotid Artery Compressions. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3459

Jeffrey Townsend

New Haven, CT
Professor of Biostatistics and Ecology & Evolutionary Biology
Most Relevant Research Interests
Genetics
Genetics
Genetics
Other Research Interests (76)
Statistics
cancer genetics
disease modeling
antibiotic resistance
Evolutionary Genomics
And 71 more
About
Jeffrey Townsend is a Professor of Organismic and Evolutionary Biology at Yale University. He received his Ph.D. from Harvard University in 2002 and his Sc.B. from Brown University in 1994. He has been a teacher at St. Ann's School and an Assistant Professor at the University of Connecticut. He is currently the Elihu Professor of Biostatistics at Yale University.
Most Relevant Publications (64+)

207 total publications

The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits

Systematic Biology / Apr 01, 2009

Schoch, C. L., Sung, G.-H., López-Giráldez, F., Townsend, J. P., Miadlikowska, J., Hofstetter, V., Robbertse, B., Matheny, P. B., Kauff, F., Wang, Z., Gueidan, C., Andrie, R. M., Trippe, K., Ciufetti, L. M., Wynns, A., Fraker, E., Hodkinson, B. P., Bonito, G., Groenewald, J. Z., … Spatafora, J. W. (2009). The Ascomycota Tree of Life: A Phylum-wide Phylogeny Clarifies the Origin and Evolution of Fundamental Reproductive and Ecological Traits. Systematic Biology, 58(2), 224–239. https://doi.org/10.1093/sysbio/syp020

Profiling Phylogenetic Informativeness

Systematic Biology / Apr 01, 2007

Townsend, J. P. (2007). Profiling Phylogenetic Informativeness. Systematic Biology, 56(2), 222–231. https://doi.org/10.1080/10635150701311362

Phylogenetic and phylogenomic overview of the Polyporales

Mycologia / Nov 01, 2013

Binder, M., Justo, A., Riley, R., Salamov, A., Lopez-Giraldez, F., Sjökvist, E., Copeland, A., Foster, B., Sun, H., Larsson, E., Larsson, K.-H., Townsend, J., Grigoriev, I. V., & Hibbett, D. S. (2013). Phylogenetic and phylogenomic overview of the Polyporales. Mycologia, 105(6), 1350–1373. https://doi.org/10.3852/13-003

Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays

BMC Genomics / Oct 02, 2003

Townsend, J. P. (2003). Multifactorial experimental design and the transitivity of ratios with spotted DNA microarrays. BMC Genomics, 4(1). https://doi.org/10.1186/1471-2164-4-41

Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays

Gene / May 01, 2004

Lim, C. R., Fukakusa, A., & Matsubara, K. (2004). Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays. Gene, 333, 3–13. https://doi.org/10.1016/j.gene.2004.02.026

Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes

Genetics / May 01, 2003

Townsend, J. P., Nielsen, K. M., Fisher, D. S., & Hartl, D. L. (2003). Horizontal Acquisition of Divergent Chromosomal DNA in Bacteria: Effects of Mutator Phenotypes. Genetics, 164(1), 13–21. https://doi.org/10.1093/genetics/164.1.13

Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa

mSystems / Jun 28, 2022

Wang, Z., Lopez-Giraldez, F., Slot, J., Yarden, O., Trail, F., & Townsend, J. P. (2022). Secondary Metabolism Gene Clusters Exhibit Increasingly Dynamic and Differential Expression during Asexual Growth, Conidiation, and Sexual Development in Neurospora crassa. MSystems, 7(3). https://doi.org/10.1128/msystems.00232-22

Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes

Molecular Biology and Evolution / Apr 26, 2022

Cannataro, V. L., Mandell, J. D., & Townsend, J. P. (2022). Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes. Molecular Biology and Evolution, 39(5). https://doi.org/10.1093/molbev/msac084

Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales)

Microbiology Resource Announcements / Feb 17, 2022

Gortikov, M., Wang, Z., Steindorff, A. S., Grigoriev, I. V., Druzhinina, I. S., Townsend, J. P., & Yarden, O. (2022). Sequencing and Analysis of the Entire Genome of the Mycoparasitic Bioeffector Fungus Trichoderma asperelloides Strain T 203 (Hypocreales). Microbiology Resource Announcements, 11(2). https://doi.org/10.1128/mra.00995-21

Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy

PLOS Computational Biology / Jun 09, 2021

Wells, C. R., Cao, Y., Durham, D. P., Byrareddy, S. N., Ansari, A. A., Ruddle, N. H., Townsend, J. P., Galvani, A. P., & Perelson, A. S. (2021). Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy. PLOS Computational Biology, 17(6), e1009031. https://doi.org/10.1371/journal.pcbi.1009031

Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification

Genome Biology and Evolution / Nov 16, 2020

Dornburg, A., Wang, Z., Wang, J., Mo, E. S., López-Giráldez, F., & Townsend, J. P. (2020). Comparative Genomics within and across Bilaterians Illuminates the Evolutionary History of ALK and LTK Proto-Oncogene Origination and Diversification. Genome Biology and Evolution, 13(1). https://doi.org/10.1093/gbe/evaa228

Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi

Molecular Biology and Evolution / Mar 19, 2020

Merényi, Z., Prasanna, A. N., Wang, Z., Kovács, K., Hegedüs, B., Bálint, B., Papp, B., Townsend, J. P., & Nagy, L. G. (2020). Unmatched Level of Molecular Convergence among Deeply Divergent Complex Multicellular Fungi. Molecular Biology and Evolution, 37(8), 2228–2240. https://doi.org/10.1093/molbev/msaa077

Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model

Systematic Biology / Oct 29, 2019

Scott, J. G., Maini, P. K., Anderson, A. R. A., & Fletcher, A. G. (2019). Inferring Tumor Proliferative Organization from Phylogenetic Tree Measures in a Computational Model. Systematic Biology, 69(4), 623–637. https://doi.org/10.1093/sysbio/syz070

Molecular Biology and Evolution of Cancer: From Discovery to Action

Molecular Biology and Evolution / Oct 23, 2019

Somarelli, J. A., Gardner, H., Cannataro, V. L., Gunady, E. F., Boddy, A. M., Johnson, N. A., Fisk, J. N., Gaffney, S. G., Chuang, J. H., Li, S., Ciccarelli, F. D., Panchenko, A. R., Megquier, K., Kumar, S., Dornburg, A., DeGregori, J., & Townsend, J. P. (2019). Molecular Biology and Evolution of Cancer: From Discovery to Action. Molecular Biology and Evolution, 37(2), 320–326. https://doi.org/10.1093/molbev/msz242

Modelling microbial infection to address global health challenges

Nature Microbiology / Sep 20, 2019

Fitzpatrick, M. C., Bauch, C. T., Townsend, J. P., & Galvani, A. P. (2019). Modelling microbial infection to address global health challenges. Nature Microbiology, 4(10), 1612–1619. https://doi.org/10.1038/s41564-019-0565-8

APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma

Oncogene / Jan 15, 2019

Cannataro, V. L., Gaffney, S. G., Sasaki, T., Issaeva, N., Grewal, N. K. S., Grandis, J. R., Yarbrough, W. G., Burtness, B., Anderson, K. S., & Townsend, J. P. (2019). APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma. Oncogene, 38(18), 3475–3487. https://doi.org/10.1038/s41388-018-0657-6

Wagging the long tail of drivers of prostate cancer

PLOS Genetics / Jan 17, 2019

Cannataro, V. L., & Townsend, J. P. (2019). Wagging the long tail of drivers of prostate cancer. PLOS Genetics, 15(1), e1007820. https://doi.org/10.1371/journal.pgen.1007820

Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets

Systematic Biology / Jun 25, 2018

Dornburg, A., Su, Z., & Townsend, J. P. (2018). Optimal Rates for Phylogenetic Inference and Experimental Design in the Era of Genome-Scale Data Sets. Systematic Biology, 68(1), 145–156. https://doi.org/10.1093/sysbio/syy047

Somatic evolutionary timings of driver mutations

BMC Cancer / Jan 18, 2018

Gomez, K., Miura, S., Huuki, L. A., Spell, B. S., Townsend, J. P., & Kumar, S. (2018). Somatic evolutionary timings of driver mutations. BMC Cancer, 18(1). https://doi.org/10.1186/s12885-017-3977-y

Neutral Theory and the Somatic Evolution of Cancer

Molecular Biology and Evolution / Apr 19, 2018

Cannataro, V. L., & Townsend, J. P. (2018). Neutral Theory and the Somatic Evolution of Cancer. Molecular Biology and Evolution, 35(6), 1308–1315. https://doi.org/10.1093/molbev/msy079

Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C

Oncogene / Feb 16, 2018

Cannataro, V. L., Gaffney, S. G., Stender, C., Zhao, Z.-M., Philips, M., Greenstein, A. E., & Townsend, J. P. (2018). Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C. Oncogene, 37(18), 2444–2455. https://doi.org/10.1038/s41388-017-0105-z

Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues

Molecular Ecology / Dec 12, 2017

Wang, Z., Wang, J., Li, N., Li, J., Trail, F., Dunlap, J. C., & Townsend, J. P. (2017). Light sensing by opsins and fungal ecology: NOP‐1 modulates entry into sexual reproduction in response to environmental cues. Molecular Ecology, 27(1), 216–232. Portico. https://doi.org/10.1111/mec.14425

Neutral Theory and the Somatic Evolution of Cancer

Molecular Biology and Evolution / May 14, 2018

Neutral Theory and the Somatic Evolution of Cancer. (2018). Molecular Biology and Evolution, 35(6), 1561–1561. https://doi.org/10.1093/molbev/msy100

Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence

Molecular Biology and Evolution / Jul 28, 2017

Zhao, Z.-M., Campbell, M. C., Li, N., Lee, D. S. W., Zhang, Z., & Townsend, J. P. (2017). Detection of Regional Variation in Selection Intensity within Protein-Coding Genes Using DNA Sequence Polymorphism and Divergence. Molecular Biology and Evolution, 34(11), 3006–3022. https://doi.org/10.1093/molbev/msx213

Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana

Genetics / Aug 01, 2017

Park, B., Rutter, M. T., Fenster, C. B., Symonds, V. V., Ungerer, M. C., & Townsend, J. P. (2017). Distributions of Mutational Effects and the Estimation of Directional Selection in Divergent Lineages of Arabidopsis thaliana. Genetics, 206(4), 2105–2117. https://doi.org/10.1534/genetics.116.199190

The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi

PLOS Genetics / Jul 13, 2017

Trail, F., Wang, Z., Stefanko, K., Cubba, C., & Townsend, J. P. (2017). The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi. PLOS Genetics, 13(7), e1006867. https://doi.org/10.1371/journal.pgen.1006867

New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset

Molecular Phylogenetics and Evolution / May 01, 2017

Dornburg, A., Townsend, J. P., Brooks, W., Spriggs, E., Eytan, R. I., Moore, J. A., Wainwright, P. C., Lemmon, A., Lemmon, E. M., & Near, T. J. (2017). New insights on the sister lineage of percomorph fishes with an anchored hybrid enrichment dataset. Molecular Phylogenetics and Evolution, 110, 27–38. https://doi.org/10.1016/j.ympev.2017.02.017

PhyloOncology: Understanding cancer through phylogenetic analysis

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer / Apr 01, 2017

Somarelli, J. A., Ware, K. E., Kostadinov, R., Robinson, J. M., Amri, H., Abu-Asab, M., Fourie, N., Diogo, R., Swofford, D., & Townsend, J. P. (2017). PhyloOncology: Understanding cancer through phylogenetic analysis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1867(2), 101–108. https://doi.org/10.1016/j.bbcan.2016.10.006

A working model of the deep relationships of diverse modern human genetic lineages outside of Africa

Molecular Biology and Evolution / Jan 10, 2017

Lipson, M., & Reich, D. (2017). A working model of the deep relationships of diverse modern human genetic lineages outside of Africa. Molecular Biology and Evolution, msw293. https://doi.org/10.1093/molbev/msw293

Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification

Molecular Biology and Evolution / Jan 12, 2017

Wu, W. K. K., Li, X., Wang, X., Dai, R. Z. W., Cheng, A. S. L., Wang, M. H. T., Kwong, T., Chow, T. C., Yu, J., Chan, M. T. V., & Wong, S. H. (2017). Oncogenes without a neighboring tumor-suppressor gene are more prone to amplification. Molecular Biology and Evolution, msw295. https://doi.org/10.1093/molbev/msw295

Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection

Molecular Biology and Evolution / Apr 20, 2015

Hodgins-Davis, A., Rice, D. P., & Townsend, J. P. (2015). Gene Expression Evolves under a House-of-Cards Model of Stabilizing Selection. Molecular Biology and Evolution, 32(8), 2130–2140. https://doi.org/10.1093/molbev/msv094

H-CLAP: hierarchical clustering within a linear array with an application in genetics

Statistical Applications in Genetics and Molecular Biology / Jan 01, 2015

Ghosh, S., & Townsend, J. P. (2015). H-CLAP: hierarchical clustering within a linear array with an application in genetics. Statistical Applications in Genetics and Molecular Biology, 14(2). https://doi.org/10.1515/sagmb-2013-0076

The peopling of the African continent and the diaspora into the new world

Current Opinion in Genetics & Development / Dec 01, 2014

Campbell, M. C., Hirbo, J. B., Townsend, J. P., & Tishkoff, S. A. (2014). The peopling of the African continent and the diaspora into the new world. Current Opinion in Genetics & Development, 29, 120–132. https://doi.org/10.1016/j.gde.2014.09.003

Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa

G3 Genes|Genomes|Genetics / Sep 01, 2014

Wu, C., Yang, F., Smith, K. M., Peterson, M., Dekhang, R., Zhang, Y., Zucker, J., Bredeweg, E. L., Mallappa, C., Zhou, X., Lyubetskaya, A., Townsend, J. P., Galagan, J. E., Freitag, M., Dunlap, J. C., Bell-Pedersen, D., & Sachs, M. S. (2014). Genome-Wide Characterization of Light-Regulated Genes inNeurospora crassa. G3 Genes|Genomes|Genetics, 4(9), 1731–1745. https://doi.org/10.1534/g3.114.012617

Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body

PLoS Pathogens / May 08, 2014

Talbert-Slagle, K., Atkins, K. E., Yan, K.-K., Khurana, E., Gerstein, M., Bradley, E. H., Berg, D., Galvani, A. P., & Townsend, J. P. (2014). Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body. PLoS Pathogens, 10(5), e1004092. https://doi.org/10.1371/journal.ppat.1004092

Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design

Molecular Phylogenetics and Evolution / Jan 01, 2013

Moeller, A. H., & Townsend, J. P. (2013). Response to: The relative utility of sequence divergence and phylogenetic informativeness profiling in phylogenetic study design. Molecular Phylogenetics and Evolution, 66(1), 436. https://doi.org/10.1016/j.ympev.2012.09.035

Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny

Systematic Biology / Mar 03, 2012

Townsend, J. P., Su, Z., & Tekle, Y. I. (2012). Phylogenetic Signal and Noise: Predicting the Power of a Data Set to Resolve Phylogeny. Systematic Biology, 61(5), 835. https://doi.org/10.1093/sysbio/sys036

Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size

G3 Genes|Genomes|Genetics / Aug 01, 2012

Rice, D. P., & Townsend, J. P. (2012). Resampling QTL Effects in the QTL Sign Test Leads to Incongruous Sensitivity to Variance in Effect Size. G3 Genes|Genomes|Genetics, 2(8), 905–911. https://doi.org/10.1534/g3.112.003228

Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology

Fungal Genetics and Biology / Aug 01, 2012

Sikhakolli, U. R., López-Giráldez, F., Li, N., Common, R., Townsend, J. P., & Trail, F. (2012). Transcriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology. Fungal Genetics and Biology, 49(8), 663–673. https://doi.org/10.1016/j.fgb.2012.05.009

Sex-specific gene expression during asexual development of Neurospora crassa

Fungal Genetics and Biology / Jul 01, 2012

Wang, Z., Kin, K., López-Giráldez, F., Johannesson, H., & Townsend, J. P. (2012). Sex-specific gene expression during asexual development of Neurospora crassa. Fungal Genetics and Biology, 49(7), 533–543. https://doi.org/10.1016/j.fgb.2012.05.004

Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa

Fungal Genetics and Biology / May 01, 2012

Wang, Z., Lehr, N., Trail, F., & Townsend, J. P. (2012). Differential impact of nutrition on developmental and metabolic gene expression during fruiting body development in Neurospora crassa. Fungal Genetics and Biology, 49(5), 405–413. https://doi.org/10.1016/j.fgb.2012.03.004

A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data

Genetics / Apr 01, 2012

Rice, D. P., & Townsend, J. P. (2012). A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data. Genetics, 190(4), 1533–1545. https://doi.org/10.1534/genetics.111.137075

Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae

Genome Biology and Evolution / Jan 01, 2012

Hodgins-Davis, A., Adomas, A. B., Warringer, J., & Townsend, J. P. (2012). Abundant Gene-by-Environment Interactions in Gene Expression Reaction Norms to Copper within Saccharomyces cerevisiae. Genome Biology and Evolution, 4(11), 1061–1079. https://doi.org/10.1093/gbe/evs084

Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates

Molecular Phylogenetics and Evolution / Aug 01, 2011

Moeller, A. H., & Townsend, J. P. (2011). Phylogenetic informativeness profiling of 12 genes for 28 vertebrate taxa without divergence dates. Molecular Phylogenetics and Evolution, 60(2), 271–272. https://doi.org/10.1016/j.ympev.2011.04.023

Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference

Systematic Biology / Feb 08, 2011

Townsend, J. P., & Leuenberger, C. (2011). Taxon Sampling and the Optimal Rates of Evolution for Phylogenetic Inference. Systematic Biology, 60(3), 358–365. https://doi.org/10.1093/sysbio/syq097

Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny

Mycologia / Sep 01, 2010

Ohenoja, E., Wang, Z., Townsend, J. P., Mitchel, D., & Voitk, A. (2010). Northern species of earth tongue genus Thuemenidium revisited, considering morphology, ecology and molecular phylogeny. Mycologia, 102(5), 1089–1095. https://doi.org/10.3852/09-317

Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships

Systematic Biology / May 19, 2010

Townsend, J. P., & Lopez-Giraldez, F. (2010). Optimal Selection of Gene and Ingroup Taxon Sampling for Resolving Phylogenetic Relationships. Systematic Biology, 59(4), 446–457. https://doi.org/10.1093/sysbio/syq025

Identification of new molecular markers for assembling the eukaryotic tree of life

Molecular Phylogenetics and Evolution / Jun 01, 2010

Tekle, Y. I., Grant, J. R., Kovner, A. M., Townsend, J. P., & Katz, L. A. (2010). Identification of new molecular markers for assembling the eukaryotic tree of life. Molecular Phylogenetics and Evolution, 55(3), 1177–1182. https://doi.org/10.1016/j.ympev.2010.03.010

The filamentous fungal gene expression database (FFGED)

Fungal Genetics and Biology / Mar 01, 2010

Zhang, Z., & Townsend, J. P. (2010). The filamentous fungal gene expression database (FFGED). Fungal Genetics and Biology, 47(3), 199–204. https://doi.org/10.1016/j.fgb.2009.12.001

Multi-targeted priming for genome-wide gene expression assays

BMC Genomics / Aug 17, 2010

Adomas, A. B., Lopez-Giraldez, F., Clark, T. A., Wang, Z., & Townsend, J. P. (2010). Multi-targeted priming for genome-wide gene expression assays. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-477

Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences

PLoS Computational Biology / Jun 26, 2009

Zhang, Z., & Townsend, J. P. (2009). Maximum-Likelihood Model Averaging To Profile Clustering of Site Types across Discrete Linear Sequences. PLoS Computational Biology, 5(6), e1000421. https://doi.org/10.1371/journal.pcbi.1000421

Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies

Genome Biology and Evolution / Jan 01, 2009

Otto, W., Stadler, P. F., López-Giraldéz, F., Townsend, J. P., Lynch, V. J., & Wagner, G. P. (2009). Measuring Transcription Factor–Binding Site Turnover: A Maximum Likelihood Approach Using Phylogenies. Genome Biology and Evolution, 1, 85–98. https://doi.org/10.1093/gbe/evp010

Article Commentary: Snapshots of Tree Space

Evolutionary Bioinformatics / Jan 01, 2009

Wang, Z., López-Giréidez, F., & Townsend, J. P. (2009). Article Commentary: Snapshots of Tree Space. Evolutionary Bioinformatics, 5, EBO.S3416. https://doi.org/10.4137/ebo.s3416

The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree

Journal of Molecular Evolution / Aug 12, 2008

Townsend, J. P., López-Giráldez, F., & Friedman, R. (2008). The Phylogenetic Informativeness of Nucleotide and Amino Acid Sequences for Reconstructing the Vertebrate Tree. Journal of Molecular Evolution, 67(5), 437–447. https://doi.org/10.1007/s00239-008-9142-0

Sleuthing the difference a nucleotide can make

Molecular Ecology / Jun 01, 2008

TOWNSEND, J. P. (2008). Sleuthing the difference a nucleotide can make. Molecular Ecology, 17(12), 2793–2795. https://doi.org/10.1111/j.1365-294x.2008.03824.x

Quantifying variation in gene expression

Molecular Ecology / Jul 01, 2007

CLARK, T. A., & TOWNSEND, J. P. (2007). Quantifying variation in gene expression. Molecular Ecology, 16(13), 2613–2616. https://doi.org/10.1111/j.1365-294x.2007.03354.x

Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii

Fungal Genetics and Biology / Aug 01, 2006

Johannesson, H., Kasuga, T., Schaller, R. A., Good, B., Gardner, M. J., Townsend, J. P., Cole, G. T., & Taylor, J. W. (2006). Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii. Fungal Genetics and Biology, 43(8), 545–559. https://doi.org/10.1016/j.fgb.2006.02.003

Ecological and evolutionary genomics of Saccharomyces cerevisiae

Molecular Ecology / Feb 23, 2006

LANDRY, C. R., TOWNSEND, J. P., HARTL, D. L., & CAVALIERI, D. (2006). Ecological and evolutionary genomics of Saccharomyces cerevisiae. Molecular Ecology, 15(3), 575–591. https://doi.org/10.1111/j.1365-294x.2006.02778.x

Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination

Nucleic Acids Research / Nov 27, 2005

Kasuga, T. (2005). Long-oligomer microarray profiling in Neurospora crassa reveals the transcriptional program underlying biochemical and physiological events of conidial germination. Nucleic Acids Research, 33(20), 6469–6485. https://doi.org/10.1093/nar/gki953

Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii

Genetics / Sep 01, 2005

Johannesson, H., Townsend, J. P., Hung, C.-Y., Cole, G. T., & Taylor, J. W. (2005). Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii. Genetics, 171(1), 109–117. https://doi.org/10.1534/genetics.105.040923

Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster

Heredity / May 12, 2004

Townsend, J. P., & Rand, D. M. (2004). Mitochondrial genome size variation in New World and Old World populations of Drosophila melanogaster. Heredity, 93(1), 98–103. https://doi.org/10.1038/sj.hdy.6800484

Population Genetic Variation in Genome-Wide Gene Expression

Molecular Biology and Evolution / Apr 25, 2003

Townsend, J. P. (2003). Population Genetic Variation in Genome-Wide Gene Expression. Molecular Biology and Evolution, 20(6), 955–963. https://doi.org/10.1093/molbev/msg106

Pathway Processor: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks

Genome Research / Jul 01, 2002

Grosu, P., Townsend, J. P., Hartl, D. L., & Cavalieri, D. (2002). <tt>Pathway Processor</tt>: A Tool for Integrating Whole-Genome Expression Results into Metabolic Networks. Genome Research, 12(7), 1121–1126. https://doi.org/10.1101/gr.226602

Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica

Molecular Biology and Evolution / Feb 01, 2000

Bustamante, C. D., Townsend, J. P., & Hartl, D. L. (2000). Solvent Accessibility and Purifying Selection Within Proteins of Escherichia coli and Salmonella enterica. Molecular Biology and Evolution, 17(2), 301–308. https://doi.org/10.1093/oxfordjournals.molbev.a026310

Edoardo Airoldi

Professor of Statistics & Data Science Temple University & PI, Harvard University
Most Relevant Research Interests
Genetics
Other Research Interests (63)
Statistics
Causal Inference
Network Science
Statistical Machine Learning
Computational Biology
And 58 more
About
Edoardo Airoldi is a Professor in the Department of Machine Learning at Temple University. He is also the Director of the Center for Machine Learning and Health. He is a world-renowned expert in the fields of machine learning and artificial intelligence, with a focus on applications to health. Airoldi is a member of the prestigious Association for the Advancement of Artificial Intelligence (AAAI) and the International Machine Learning Society (IMLS). He has published over 200 papers in leading journals and conferences, and his work has been covered by various media outlets including The New York Times, The Wall Street Journal, The Economist, and Wired.
Most Relevant Publications (6+)

106 total publications

Post-transcriptional regulation across human tissues

PLOS Computational Biology / May 08, 2017

Franks, A., Airoldi, E., & Slavov, N. (2017). Post-transcriptional regulation across human tissues. PLOS Computational Biology, 13(5), e1005535. https://doi.org/10.1371/journal.pcbi.1005535

Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data

Molecular Biology and Evolution / Mar 14, 2013

Wallace, E. W. J., Airoldi, E. M., & Drummond, D. A. (2013). Estimating Selection on Synonymous Codon Usage from Noisy Experimental Data. Molecular Biology and Evolution, 30(6), 1438–1453. https://doi.org/10.1093/molbev/mst051

Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells

PLoS Computational Biology / Dec 16, 2010

Markowetz, F., Mulder, K. W., Airoldi, E. M., Lemischka, I. R., & Troyanskaya, O. G. (2010). Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-Depleted Murine Embryonic Stem Cells. PLoS Computational Biology, 6(12), e1001034. https://doi.org/10.1371/journal.pcbi.1001034

Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

PLOS Genetics / May 07, 2015

Csárdi, G., Franks, A., Choi, D. S., Airoldi, E. M., & Drummond, D. A. (2015). Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast. PLOS Genetics, 11(5), e1005206. https://doi.org/10.1371/journal.pgen.1005206

Predicting Cellular Growth from Gene Expression Signatures

PLoS Computational Biology / Jan 02, 2009

Airoldi, E. M., Huttenhower, C., Gresham, D., Lu, C., Caudy, A. A., Dunham, M. J., Broach, J. R., Botstein, D., & Troyanskaya, O. G. (2009). Predicting Cellular Growth from Gene Expression Signatures. PLoS Computational Biology, 5(1), e1000257. https://doi.org/10.1371/journal.pcbi.1000257

Getting Started in Probabilistic Graphical Models

PLoS Computational Biology / Dec 07, 2007

Airoldi, E. M. (2007). Getting Started in Probabilistic Graphical Models. PLoS Computational Biology, 3(12), e252. https://doi.org/10.1371/journal.pcbi.0030252

Giuliana Noratto

Food Scientist PhD and Registered Dietician - Texas A&M University
Most Relevant Research Interests
Genetics
Genetics
Genetics
Other Research Interests (47)
Food Science
human nutrition
disease prevention and treatment
Nutrition
Human Health
And 42 more
About
Dr. Giuliana Noratto is a senior associate research scientist at Texas A&M AgriLife. She received her Ph.D. in food science and technology from Texas A&M University System, and her M.Sc. in food science and technology from Universidad Nacional Agraria La Molina. She also holds a B.S. in food science and technology from Universidad Nacional Agraria La Molina. Dr. Noratto’s research interests include food safety and quality, sensory science, and food processing.
Most Relevant Publications (23+)

91 total publications

Quinoa protective effects against obesity‐induced intestinal inflammation

The FASEB Journal / Apr 01, 2015

Noratto, G., Carrion‐Rabanal, R., Medina, G., Mencia, A., Mohanty, I., Gonzalez, D., & Murphy, K. (2015). Quinoa protective effects against obesity‐induced intestinal inflammation. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.602.9

Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells

The FASEB Journal / Mar 01, 2006

Mo, H., Noratto, G., Fernandes, N., Hussein, D., Sodhani, S., & Cisneros‐Zevallos, L. (2006). Fractions of cottonseed and peanut extracts suppress the proliferation of human LNCaP and DU145 prostate carcinoma cells. The FASEB Journal, 20(4). Portico. https://doi.org/10.1096/fasebj.20.4.a565-b

Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD)

The FASEB Journal / Apr 01, 2015

Ravisankar, S., Campos Gutierrez, D., Chirinos, R., & Noratto, G. (2015). Quinoa (Chenopodium Quinoa) Peptides Protect Human Umbilical Vein Endothelial Cells (HUVEC) Against Risk Markers For Cardiovascular Disease (CVD). The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.923.10

Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia

The FASEB Journal / Apr 01, 2013

Noratto, G., Condezo‐Hoyos, L., Gasco, M., & Gonzales, G. (2013). Lepidium meyenii (maca) consumption prevent benign prostatic hyperplasia. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.861.25

Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice

The FASEB Journal / Apr 01, 2015

Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283

Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice

The FASEB Journal / Apr 01, 2015

Atienza, L., Garcia Perez, E., & Noratto, G. (2015). Effects of Raspberry on Biomarkers of Diabetes, Cardiovascular Disease (CVD) and Oxidative Stress in Obese Diabetic (db/db) Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.lb283

Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5)

The FASEB Journal / Apr 01, 2014

Yuan, J., Noratto, K., Munske, G., Pilla, P., Mohanty, I., Alcantara Zapata, D., & Noratto, G. (2014). Potential of glycated proteins produced during aging of cheddar cheese to modulate fecal bacteria from obese mice ex vivo and protect against colon inflammation (1018.5). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1018.5

Quinoa as source of bioactive compounds with potential for intestinal health (647.18)

The FASEB Journal / Apr 01, 2014

Carrion, R., Murphy, K., Ganjyal, G., Kowalski, R., & Noratto, G. (2014). Quinoa as source of bioactive compounds with potential for intestinal health (647.18). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.647.18

Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells

The FASEB Journal / Apr 01, 2009

Del Follo, A., Noratto, G. D., & Mertens‐Talcott, S. (2009). Resveratrol and quercetin target microRNA 27a in their anti‐cancer effects in colon cancer cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.4

Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells

The FASEB Journal / Apr 01, 2009

Townsley, E. D., Noratto, G., Angel, G., Del Follo, A., Byrne, D., & Mertens‐Talcott, S. (2009). Plum polyphenolics decrease oxidative stress and inflammation in vascular endothelial cells. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.717.12

Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity

The FASEB Journal / Apr 01, 2015

yuan, jialing, chew, B., & noratto, giuliana. (2015). Apple Consumption Protects Sprague Dawley Rats Against High Fat Diet‐induced Metabolic Disorders Associated With Obesity. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.276.7

Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice

The FASEB Journal / Apr 01, 2015

Noratto, G., García‐Pérez, E., Ivanov, I., & Mills, D. (2015). Whole‐Wheat Supplemented Diet Changed Fecal Microbial Ecology of Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.385.5

The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3)

The FASEB Journal / Apr 01, 2014

Bibi, S., Balemba, O., Carrion‐Rabanal, R., Nyavor, Y., & Noratto, G. (2014). The anti‐inflammatory effects of manniflavanone extracted from Garcinia buchananii bark in obesity‐induced mice model (259.3). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.259.3

Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk

The FASEB Journal / Apr 01, 2012

Noratto, G. D., Chirinos, R., Campos, D., Larondelle, Y., Arbizu, S., Dos Santos, M. M., & Mertens-Talcott, S. (2012). Sacha inchi (Plukenetia volubillis L.) oil as novel source of dietary fat to prevent inflammation and cardiovascular disease risk. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.626.13

Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target

The FASEB Journal / Apr 01, 2015

Ravisankar, S., & Noratto, G. (2015). Ripened Cheddar Cheese Peptides Protect Human Vein Endothelial Cells (HUVEC) Against Expression Of Risk Markers For CVD: Role Of Paroaxonase‐2 (PON‐2) As Peptide Molecular Target. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.130.7

Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice

The FASEB Journal / Apr 01, 2015

Mohanty, I., yuan, J., Noratto, G., Balemba, O., & Morris, C. (2015). Whole Wheat‐supplemented Diet Prevents Risk Biomarkers of Cardiovascular Diseases in Obese Diabetic Mice. The FASEB Journal, 29(S1). Portico. https://doi.org/10.1096/fasebj.29.1_supplement.254.3

Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12)

The FASEB Journal / Apr 01, 2014

Ravisankar, S., Yuan, J., Munske, G., & Noratto, G. (2014). Ripening of cheddar cheese with Lactobacillus helveticus as adjunct culture produces peptides that protect human vein endothelial cells against inflammatory markers relevant to cardiovascular disease (1034.12). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.1034.12

Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7)

The FASEB Journal / Apr 01, 2014

Noratto, G., Mohanty, I., Alcantara Zapata, D., & Chew, B. (2014). Wheat phenolics can prevent inflammation in human umbilical endothelial cells: effects on biomarkers relevant to development of cardiovascular diseases (249.7). The FASEB Journal, 28(S1). Portico. https://doi.org/10.1096/fasebj.28.1_supplement.249.7

Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes

The FASEB Journal / Apr 01, 2013

Martino, H., Noratto, G., Dias, M., Talcott, S., & Mertens‐Talcott, S. (2013). Anti‐obesity and Anti‐inflammatory Effect of Acai Polyphenols in 3T3‐L1 Adipocytes. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.865.5

Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats

The FASEB Journal / Apr 01, 2012

Noratto, G. D., Simbo, S., Martino, H. S., Byrne, D., & Mertens-Talcott, S. (2012). Plum polyphenolics prevent adipogenesis, inflammation and obesity‐induced metabolic disorders in obese Zucker rats. The FASEB Journal, 26(S1). Portico. https://doi.org/10.1096/fasebj.26.1_supplement.364.3

Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a

The FASEB Journal / Apr 01, 2011

Noratto, G. D., Simbo, S. Y., Safe, S., & Mertens‐Talcott, S. U. (2011). Reduced expression of pro‐invasive genes in xenographs of MDA‐MB‐231 breast cancer cells by Betulinic Acid is mediated by down‐regulation of microRNA27a. The FASEB Journal, 25(S1). Portico. https://doi.org/10.1096/fasebj.25.1_supplement.213.4

Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC)

The FASEB Journal / Apr 01, 2010

Angel‐Morales, G., Noratto, G., & Mertens‐Talcott, S. (2010). Turmeric curcuminoids (Curcuma longa L.) interacts with microRNAs in the regulation of inflammation on Human Umbilical Vein Endothelial Cells (HUVEC). The FASEB Journal, 24(S1). Portico. https://doi.org/10.1096/fasebj.24.1_supplement.924.5

Technical note: Optimization of lactose quantification based on coupled enzymatic reactions

Journal of Dairy Science / Apr 01, 2014

Condezo-Hoyos, L., Mohanty, I. P., & Noratto, G. D. (2014). Technical note: Optimization of lactose quantification based on coupled enzymatic reactions. Journal of Dairy Science, 97(4), 2066–2070. https://doi.org/10.3168/jds.2013-7436

Ping Luo

Postdoctoral Researcher at Princess Margaret Cancer Centre with experience in deep learning
Most Relevant Research Interests
Genetics
Genetics
Other Research Interests (25)
single-cell genomics
deep learning
complex network analysis
Genetics (clinical)
Molecular Medicine
And 20 more
About
8 years of science and engineering experience integrating multi-omics data to identify biomarkers for cancer studies. Seeking to apply data analytics expertise to develop new diagnosis and treatment strategies.
Most Relevant Publications (5+)

23 total publications

deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks

Frontiers in Genetics / Jan 29, 2019

Luo, P., Ding, Y., Lei, X., & Wu, F.-X. (2019). deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00013

Disease Gene Prediction by Integrating PPI Networks, Clinical RNA-Seq Data and OMIM Data

IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jan 01, 2019

Luo, P., Tian, L.-P., Ruan, J., & Wu, F.-X. (2019). Disease Gene Prediction by Integrating PPI Networks, Clinical RNA-Seq Data and OMIM Data. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 16(1), 222–232. https://doi.org/10.1109/tcbb.2017.2770120

Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning

Frontiers in Genetics / Apr 02, 2019

Luo, P., Xiao, Q., Wei, P.-J., Liao, B., & Wu, F.-X. (2019). Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00270

CReSCENT: CanceR Single Cell ExpressioN Toolkit

Nucleic Acids Research / Jun 01, 2020

Mohanraj, S., Díaz-Mejía, J. J., Pham, M. D., Elrick, H., Husić, M., Rashid, S., Luo, P., Bal, P., Lu, K., Patel, S., Mahalanabis, A., Naidas, A., Christensen, E., Croucher, D., Richards, L. M., Shooshtari, P., Brudno, M., Ramani, A. K., & Pugh, T. J. (2020). CReSCENT: CanceR Single Cell ExpressioN Toolkit. Nucleic Acids Research, 48(W1), W372–W379. https://doi.org/10.1093/nar/gkaa437

Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets

Computational and Structural Biotechnology Journal / Jan 01, 2022

Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029

Marina Baretti

Baltimore, Maryland, United States of America
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
Most Relevant Research Interests
Genetics
Other Research Interests (19)
Oncology
Pharmacology (medical)
Pharmacology
Hematology
Gastroenterology
And 14 more
About
Throughout my training, I have been focused toward my ultimate goal of becoming a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions. My clinical research is centered on the development of novel agents in GI cancers, with particular interest in combinatorial approaches of epigenetic therapies and immunotherapies combinations. I ran the first phase II study of combination epigenetic therapy and immunotherapy in advanced pancreatic adenocarcinoma and cholangiocarcinoma, working with a collaborative team that incorporates leading experts in cancer immunology, epigenetics and drug development. I was awarded the 2018 ASCO Conquer Cancer Foundation Young Investigator Award for this project.  Together with Dr. Yarchoan, we are running a clinical trial of a novel neoantigen-specific vaccine in combination with immune checkpoint inhibitors for advanced fibrolamellar carcinoma (FLC) (NCT04248569). My laboratory focus has been on developing and validating a preclinical mouse model of FLC to investigate mechanisms underlying FLC pathogenesis, and will become a critical tool for investigating novel therapeutic strategies in FLC.
Most Relevant Publications (1+)

57 total publications

A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence

Clinical Epigenetics / Dec 01, 2022

Heumann, T. R., Baretti, M., Sugar, E. A., Durham, J. N., Linden, S., Lopez-Vidal, T. Y., Leatherman, J., Cope, L., Sharma, A., Weekes, C. D., O’Dwyer, P. J., Reiss, K. A., Monga, D. K., Ahuja, N., & Azad, N. S. (2022). A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence. Clinical Epigenetics, 14(1). https://doi.org/10.1186/s13148-022-01367-8

Peter Reich

Director of the Institute for Global Change Biology (IGCB)
Most Relevant Research Interests
Genetics
Other Research Interests (44)
Multidisciplinary
General Earth and Planetary Sciences
Ecology
Ecology, Evolution, Behavior and Systematics
General Environmental Science
And 39 more
About
Dr. Peter Reich, a renowned expert in forest ecology and climate change science, is the Director of the Institute for Global Change Biology (IGCB) at the University of Michigan. Reich, who has conducted global change research on plants, soils, and ecosystems across a range of scales, will maintain a joint affiliation at the University of Minnesota, where he is a Regents Professor. Previously, Reich was the Chief Scientist at the Hawkesbury Institute for the Environment at Western Sydney University in Australia from 2011 to 2021. He is a member of the National Academy of Sciences of the United States and the American Academy of Arts and Sciences, a fellow of the Ecological Society of America, and a BBVA Prize Laureate (BBVA Foundation Frontiers of Knowledge Award in Ecology and Conservation Biology). He also helped launch the science education channel, MinuteEarth, which has more than 400 million views on YouTube and other platforms. According to Research.com, Reich is the #1 scientist in the world in the field of ecology and evolution.
Most Relevant Publications (7+)

509 total publications

Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment

Molecular Ecology / Jul 29, 2016

Nguyen, N. H., Williams, L. J., Vincent, J. B., Stefanski, A., Cavender-Bares, J., Messier, C., Paquette, A., Gravel, D., Reich, P. B., & Kennedy, P. G. (2016). Ectomycorrhizal fungal diversity and saprotrophic fungal diversity are linked to different tree community attributes in a field-based tree experiment. Molecular Ecology, 25(16), 4032–4046. Portico. https://doi.org/10.1111/mec.13719

Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output

American Journal of Botany / Oct 01, 2015

Jacques, M.-H., Lapointe, L., Rice, K., Montgomery, R. A., Stefanski, A., & Reich, P. B. (2015). Responses of two understory herbs,Maianthemum canadenseandEurybia macrophylla, to experimental forest warming: Early emergence is the key to enhanced reproductive output. American Journal of Botany, 102(10), 1610–1624. Portico. https://doi.org/10.3732/ajb.1500046

Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities

Mycologia / Jul 01, 2009

Dickie, I. A., Dentinger, B. T. M., Avis, P. G., McLaughlin, D. J., & Reich, P. B. (2009). Ectomycorrhizal fungal communities of oak savanna are distinct from forest communities. Mycologia, 101(4), 473–483. https://doi.org/10.3852/08-178

Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen

Physiologia Plantarum / Aug 01, 1996

Volin, J. C., & Reich, P. B. (1996). Interaction of elevated CO2 and O3 on growth, photosynthesis and respiration of three perennial species grown in low and high nitrogen. Physiologia Plantarum, 97(4), 674–684. https://doi.org/10.1034/j.1399-3054.1996.970407.x

Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings

Physiologia Plantarum / Dec 01, 1993

Kruger, E. L., & Reich, P. B. (1993). Coppicing affects growth, root:shoot relations and ecophysiology of potted Quercus rubra seedlings. Physiologia Plantarum, 89(4), 751–760. https://doi.org/10.1111/j.1399-3054.1993.tb05281.x

Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean

Physiologia Plantarum / Jan 01, 1985

Reich, P. B., Schoettle, A. W., & Amundson, R. G. (1985). Effects of low concentrations of O3, leaf age and water stress on leaf diffusive conductance and water use efficiency in soybean. Physiologia Plantarum, 63(1), 58–64. https://doi.org/10.1111/j.1399-3054.1985.tb02818.x

Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark

Physiologia Plantarum / Aug 01, 1984

Reich, P. B. (1984). Oscillations in stomatal conductance of hybrid poplar leaves in the light and dark. Physiologia Plantarum, 61(4), 541–548. https://doi.org/10.1111/j.1399-3054.1984.tb05167.x

Katelyn Katelyn Masiuk

Co-Founder and CSO at Immunovec
Most Relevant Research Interests
Genetics
Genetics
Genetics
Genetics
Other Research Interests (23)
Cell Biology
Molecular Medicine
Molecular Biology
Molecular Medicine
Drug Discovery
And 18 more
About
Katelyn Masiuk is the co-founder and Chief Scientific Officer of ImmunoVec. She is also a medical student in the MSTP program at UCLA. Her research interests include immunology and virology.
Most Relevant Publications (5+)

13 total publications

Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates

Molecular Therapy / Aug 01, 2019

Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014

Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome

Cell Stem Cell / Feb 01, 2019

Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003

PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector

Molecular Therapy - Methods &amp; Clinical Development / Jun 01, 2019

Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods &amp; Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005

Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells

Molecular Therapy / Sep 01, 2017

Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023

Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study

Human Gene Therapy / Oct 01, 2018

Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061

Asst. Prof. Eng. Davide Verzotto, Ph.D.

Assistant Professor of Computer Science, Centre for Higher Defence Studies (CASD) - School of Advanced Studies, Italian Defence General Staff, Rome
Most Relevant Research Interests
Genetics
Other Research Interests (22)
Algorithms & Data Structures
Bioinformatics & Computational Biology
Machine Learning
Scalable
Multidisciplinary
And 17 more
About
Algorithms & Information Intelligence, Pattern Discovery Bioinformatics & Computational Biology/Genomics Scalable Data Mining & Machine Learning
Most Relevant Publications (4+)

40 total publications

The Irredundant Class Method for Remote Homology Detection of Protein Sequences

Journal of Computational Biology / Dec 01, 2011

Comin, M., & Verzotto, D. (2011). The Irredundant Class Method for Remote Homology Detection of Protein Sequences. Journal of Computational Biology, 18(12), 1819–1829. https://doi.org/10.1089/cmb.2010.0171

Beyond Fixed-Resolution Alignment-Free Measures for Mammalian Enhancers Sequence Comparison

IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jul 01, 2014

Comin, M., & Verzotto, D. (2014). Beyond Fixed-Resolution Alignment-Free Measures for Mammalian Enhancers Sequence Comparison. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(4), 628–637. https://doi.org/10.1109/tcbb.2014.2306830

2014 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 11

IEEE/ACM Transactions on Computational Biology and Bioinformatics / Nov 01, 2014

2014 Index IEEE/ACM Transactions on Computational Biology and Bioinformatics Vol. 11. (2014). IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(6), 1273–1292. https://doi.org/10.1109/tcbb.2014.2381091

Guest editorial for the 12th Asia Pacific Bioinformatics Conference

IEEE/ACM Transactions on Computational Biology and Bioinformatics / Jul 01, 2014

Zhou, S., & Phoebe Chen, Y.-P. (2014). Guest editorial for the 12th Asia Pacific Bioinformatics Conference. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11(4), 614–615. https://doi.org/10.1109/tcbb.2014.2327487

Kayvan Najarian

Professor of Comp Med and Bioinf, Emergency Med, and Electrical and Comp Engineering
Most Relevant Research Interests
Genetics
Other Research Interests (40)
biomedical inforamtics
bioinformatics
singal processing
image processing
machine learning
And 35 more
Most Relevant Publications (1+)

108 total publications

Deep learning in pharmacogenomics: from gene regulation to patient stratification

Pharmacogenomics / May 01, 2018

Kalinin, A. A., Higgins, G. A., Reamaroon, N., Soroushmehr, S., Allyn-Feuer, A., Dinov, I. D., Najarian, K., & Athey, B. D. (2018). Deep learning in pharmacogenomics: from gene regulation to patient stratification. Pharmacogenomics, 19(7), 629–650. https://doi.org/10.2217/pgs-2018-0008

Matthew Laye, Ph.D.

Medical Physiology Teacher, Data Scientist, Endurance Coach, Wearable Technology Consultant, Writer About Research
Most Relevant Research Interests
Genetics
Other Research Interests (26)
Physiology
Hepatology
Physiology (medical)
Gastroenterology
Hepatology
And 21 more
Most Relevant Publications (4+)

55 total publications

Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners

Disease Markers / Jan 01, 2015

Laye, M. J., Nielsen, M. B., Hansen, L. S., Knudsen, T., & Pedersen, B. K. (2015). Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners. Disease Markers, 2015, 1–11. https://doi.org/10.1155/2015/806418

Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation

The FASEB Journal / Apr 01, 2009

Park, Y., Lee, S., Booth, F. W., Laye, M. J., & Zhang, C. (2009). Physical activity prevents endothelial dysfunction induced by sedentary life style and high fat diet in murine coronary microcirculation. The FASEB Journal, 23(S1). Portico. https://doi.org/10.1096/fasebj.23.1_supplement.952.4

Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running

The FASEB Journal / Apr 01, 2007

Borengasser, S. J., Laye, M., Morris, T., Booth, F., & Thyfault, J. (2007). Effect of moderate fat/high sucrose diet on glycogen synthesis rates in rat skeletal muscle upon the cessation of voluntary wheel running. The FASEB Journal, 21(5). Portico. https://doi.org/10.1096/fasebj.21.5.a691-a

Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats

The FASEB Journal / Jan 01, 2007

Laye, M. J., Borengasser, S. J., Rector, R. S., Thyfault, J. P., & Booth, F. W. (2007). Adipose tissue compensates to maintain whole body insulin sensitivity 173 hours following the cessation of voluntary running in rats. The FASEB Journal, 21(6). Portico. https://doi.org/10.1096/fasebj.21.6.a936

JOAQUIN GADEA

Murcia
Professor in Physiology. Universidad de Murcia. SPAIN.
Most Relevant Research Interests
Genetics
Other Research Interests (25)
Reproductive Biology
Fertility
Reproduction
Andrology
Spermatozoa
And 20 more
Most Relevant Publications (10+)

90 total publications

Glycosidase determination in bovine oviducal fluid at the follicular and luteal phases of the oestrous cycle

Reproduction, Fertility and Development / Jan 01, 2008

Carrasco, L. C., Coy, P., Avilés, M., Gadea, J., & Romar, R. (2008). Glycosidase determination in bovine oviducal fluid at the follicular and luteal phases of the oestrous cycle. Reproduction, Fertility and Development, 20(7), 808. https://doi.org/10.1071/rd08113

Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome

Cell Discovery / Mar 19, 2019

Dorado, B., Pløen, G. G., Barettino, A., Macías, A., Gonzalo, P., Andrés-Manzano, M. J., González-Gómez, C., Galán-Arriola, C., Alfonso, J. M., Lobo, M., López-Martín, G. J., Molina, A., Sánchez-Sánchez, R., Gadea, J., Sánchez-González, J., Liu, Y., Callesen, H., Filgueiras-Rama, D., Ibáñez, B., … Andrés, V. (2019). Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome. Cell Discovery, 5(1). https://doi.org/10.1038/s41421-019-0084-z

225 DOES THE SUPPLEMENTATION OF THE BOAR SEMEN EXTENDER WITH CARNOSINE, L-HISTIDINE, AND TAURINE PRESERVE SPERM FUNCTION DURING STORAGE?

Reproduction, Fertility and Development / Jan 01, 2008

Matás, C., Gardón, J. C., Garcia-Vazquez, F. A., Pacchini, S., & Ducci, M. (2008). 225 DOES THE SUPPLEMENTATION OF THE BOAR SEMEN EXTENDER WITH CARNOSINE, L-HISTIDINE, AND TAURINE PRESERVE SPERM FUNCTION DURING STORAGE? Reproduction, Fertility and Development, 20(1), 192. https://doi.org/10.1071/rdv20n1ab225

94 ADDITION OF REDUCED GLUTATHIONE TO THAWING MEDIUM IMPROVED THE SPERM MOTILITY AND REDUCED ROS GENERATION IN FROZEN OVINE AND CAPRINE SPERMATOZOA

Reproduction, Fertility and Development / Jan 01, 2006

Gardón, J. C., Rodriquez, J. A., & Gadea, J. (2006). 94 ADDITION OF REDUCED GLUTATHIONE TO THAWING MEDIUM IMPROVED THE SPERM MOTILITY AND REDUCED ROS GENERATION IN FROZEN OVINE AND CAPRINE SPERMATOZOA. Reproduction, Fertility and Development, 18(2), 155. https://doi.org/10.1071/rdv18n2ab94

Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination

The CRISPR Journal / Feb 01, 2021

Navarro-Serna, S., Hachem, A., Canha-Gouveia, A., Hanbashi, A., Garrappa, G., Lopes, J. S., París-Oller, E., Sarrías-Gil, L., Flores-Flores, C., Bassett, A., Sánchez, R., Bermejo-Álvarez, P., Matás, C., Romar, R., Parrington, J., & Gadea, J. (2021). Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination. The CRISPR Journal, 4(1), 132–146. https://doi.org/10.1089/crispr.2020.0078

The use of a virtual journal club to promote cross-cultural learning in the reproductive sciences

Journal of Assisted Reproduction and Genetics / Sep 24, 2018

Duncan, F. E., Romar, R., Gadea, J., Kimelman, D., Wallach, H. D., Woodruff, T. K., & Jiménez-Movilla, M. (2018). The use of a virtual journal club to promote cross-cultural learning in the reproductive sciences. Journal of Assisted Reproduction and Genetics, 35(12), 2141–2147. https://doi.org/10.1007/s10815-018-1309-z

Total urokinase-type plasminogen activator (uPA) levels in seminal plasma are associated with positive assisted reproductive technology outcomes

Journal of Assisted Reproduction and Genetics / Mar 23, 2018

Martinez-Soto, J. C., Landeras, J., Mollá, M., Mondejar, I., Nicolás, M., Fernández-Olmedilla, L., Trabalón, M., Coy, P., & Gadea, J. (2018). Total urokinase-type plasminogen activator (uPA) levels in seminal plasma are associated with positive assisted reproductive technology outcomes. Journal of Assisted Reproduction and Genetics, 35(6), 1091–1101. https://doi.org/10.1007/s10815-018-1164-y

Considerations of viscosity in the preliminaries to mammalian fertilisation

Journal of Assisted Reproduction and Genetics / Jan 14, 2011

Hunter, R. H. F., Coy, P., Gadea, J., & Rath, D. (2011). Considerations of viscosity in the preliminaries to mammalian fertilisation. Journal of Assisted Reproduction and Genetics, 28(3), 191–197. https://doi.org/10.1007/s10815-010-9531-3

Effects of men and recipients’ age on the reproductive outcome of an oocyte donation program

Journal of Assisted Reproduction and Genetics / Sep 01, 2008

Campos, I., Gómez, E., Fernández-Valencia, A. L., Landeras, J., González, R., Coy, P., & Gadea, J. (2008). Effects of men and recipients’ age on the reproductive outcome of an oocyte donation program. Journal of Assisted Reproduction and Genetics, 25(9–10), 445–452. https://doi.org/10.1007/s10815-008-9255-9

Effect of exogenous DNA on bovine sperm functionality using the sperm mediated gene transfer (SMGT) technique

Molecular Reproduction and Development / Jun 21, 2010

Canovas, S., Gutierrez-Adan, A., & Gadea, J. (2010). Effect of exogenous DNA on bovine sperm functionality using the sperm mediated gene transfer (SMGT) technique. Molecular Reproduction and Development, 77(8), 687–698. https://doi.org/10.1002/mrd.21205

Dr. Susanne Ressl

Biochemist & Structural Biologist | Project & Team Leader | Creative & Translational Thinker | Problem Solver | Mentor | Educator | Consultant | Innovator | Science Communicator & Writer | Relationship Builder | Collaborator
Most Relevant Research Interests
Genetics
Genetics
Other Research Interests (43)
Structural Neuroscience of Synapse Organizing Molecules
Multidisciplinary
General Neuroscience
Virology
Microbiology
And 38 more
Most Relevant Publications (2+)

20 total publications

Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila

G3 Genes|Genomes|Genetics / Dec 01, 2020

Song, W., Ressl, S., & Tracey, W. D. (2020). Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception inDrosophila. G3 Genes|Genomes|Genetics, 10(12), 4425–4438. https://doi.org/10.1534/g3.120.401767

C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins

The FASEB Journal / Dec 18, 2020

Sticco, M. J., Peña Palomino, P. A., Lukacsovich, D., Thompson, B. L., Földy, C., Ressl, S., & Martinelli, D. C. (2020). C1QL3 promotes cell‐cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins. The FASEB Journal, 35(1). Portico. https://doi.org/10.1096/fj.202000351rr

Andrew Mikhail

Department of Kinesiology, McMaster University
Most Relevant Research Interests
Genetics
Other Research Interests (20)
skeletal muscle
neuromuscular diseases
Food Science
Nutrition and Dietetics
Physiology
And 15 more
Most Relevant Publications (5+)

14 total publications

Acute, next‐generation AMPK activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle

The FASEB Journal / Apr 05, 2023

Ng, S. Y., Mikhail, A. I., Mattina, S. R., Manta, A., Diffey, I. J., & Ljubicic, V. (2023). Acute, next‐generation <scp>AMPK</scp> activation initiates a disease‐resistant gene expression program in dystrophic skeletal muscle. The FASEB Journal, 37(5). Portico. https://doi.org/10.1096/fj.202201846rr

Dysregulation of Skeletal Muscle Mitochondrial Turnover and Dynamics Occurs During Late Symptomatic Stages of Spinal Muscular Atrophy

The FASEB Journal / May 01, 2022

Mikhail, A. I., Ng, S. Y., Osborne, A. K., Canteenwala, A. K., & Ljubicic, V. (2022). Dysregulation of Skeletal Muscle Mitochondrial Turnover and Dynamics Occurs During Late Symptomatic Stages of Spinal Muscular Atrophy. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r2886

Characterization of CARM1 Inhibition in Skeletal Muscle

The FASEB Journal / May 01, 2022

Webb, E. K., Ng, S. Y., Stouth, D. W., Lieshout, T. L., Mikhail, A. I., & Ljubicic, V. (2022). Characterization of CARM1 Inhibition in Skeletal Muscle. The FASEB Journal, 36(S1). Portico. https://doi.org/10.1096/fasebj.2022.36.s1.r3187

A Single Dose of Exercise Initiates Corrective Mitochondrial Plasticity in Myotonic Dystrophy Type 1

The FASEB Journal / May 01, 2021

Mikhail, A., Manta, A., & Ljubicic, V. (2021). A Single Dose of Exercise Initiates Corrective Mitochondrial Plasticity in Myotonic Dystrophy Type 1. The FASEB Journal, 35(S1). Portico. https://doi.org/10.1096/fasebj.2021.35.s1.01495

Acute exercise stimulates AMPK and corrects some disease characteristics in the skeletal muscle of myotonic dystrophy type 1 mice

The FASEB Journal / May 01, 2021

Manta, A., Ng, S., Mikhail, A., Mackie, M., & Ljubicic, V. (2021). Acute exercise stimulates AMPK and corrects some disease characteristics in the skeletal muscle of myotonic dystrophy type 1 mice. The FASEB Journal, 35(S1). Portico. https://doi.org/10.1096/fasebj.2021.35.s1.04602

Paul Schrater

University of Minnesota
Most Relevant Research Interests
Genetics
Other Research Interests (45)
Artificial Intelligence
Computational Psychology
Cognitive Science
General Neuroscience
Multidisciplinary
And 40 more
Most Relevant Publications (8+)

96 total publications

How Haptic Size Sensations Improve Distance Perception

PLoS Computational Biology / Jun 30, 2011

Battaglia, P. W., Kersten, D., & Schrater, P. R. (2011). How Haptic Size Sensations Improve Distance Perception. PLoS Computational Biology, 7(6), e1002080. https://doi.org/10.1371/journal.pcbi.1002080

Auditory Frequency and Intensity Discrimination Explained Using a Cortical Population Rate Code

PLoS Computational Biology / Nov 14, 2013

Micheyl, C., Schrater, P. R., & Oxenham, A. J. (2013). Auditory Frequency and Intensity Discrimination Explained Using a Cortical Population Rate Code. PLoS Computational Biology, 9(11), e1003336. https://doi.org/10.1371/journal.pcbi.1003336

Grasping Objects with Environmentally Induced Position Uncertainty

PLoS Computational Biology / Oct 16, 2009

Christopoulos, V. N., & Schrater, P. R. (2009). Grasping Objects with Environmentally Induced Position Uncertainty. PLoS Computational Biology, 5(10), e1000538. https://doi.org/10.1371/journal.pcbi.1000538

Dynamic Integration of Value Information into a Common Probability Currency as a Theory for Flexible Decision Making

PLOS Computational Biology / Sep 22, 2015

Christopoulos, V., & Schrater, P. R. (2015). Dynamic Integration of Value Information into a Common Probability Currency as a Theory for Flexible Decision Making. PLOS Computational Biology, 11(9), e1004402. https://doi.org/10.1371/journal.pcbi.1004402

Task-Specific Response Strategy Selection on the Basis of Recent Training Experience

PLoS Computational Biology / Jan 02, 2014

Fulvio, J. M., Green, C. S., & Schrater, P. R. (2014). Task-Specific Response Strategy Selection on the Basis of Recent Training Experience. PLoS Computational Biology, 10(1), e1003425. https://doi.org/10.1371/journal.pcbi.1003425

Within- and Cross-Modal Distance Information Disambiguate Visual Size-Change Perception

PLoS Computational Biology / Mar 05, 2010

Battaglia, P. W., Di Luca, M., Ernst, M. O., Schrater, P. R., Machulla, T., & Kersten, D. (2010). Within- and Cross-Modal Distance Information Disambiguate Visual Size-Change Perception. PLoS Computational Biology, 6(3), e1000697. https://doi.org/10.1371/journal.pcbi.1000697

Structure Learning in Human Sequential Decision-Making

PLoS Computational Biology / Dec 02, 2010

Acuña, D. E., & Schrater, P. (2010). Structure Learning in Human Sequential Decision-Making. PLoS Computational Biology, 6(12), e1001003. https://doi.org/10.1371/journal.pcbi.1001003

Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans

PLOS Computational Biology / Oct 01, 2021

Enachescu, V., Schrater, P., Schaal, S., & Christopoulos, V. (2021). Action planning and control under uncertainty emerge through a desirability-driven competition between parallel encoding motor plans. PLOS Computational Biology, 17(10), e1009429. https://doi.org/10.1371/journal.pcbi.1009429

Olivier Saulnier

The Hospital for Sick Children
Most Relevant Research Interests
Genetics
Other Research Interests (17)
Bioinformatics - single-cell omics
Neurology (clinical)
General Biochemistry, Genetics and Molecular Biology
Cancer Research
Oncology
And 12 more
Most Relevant Publications (3+)

25 total publications

The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival

Molecular Oncology / Aug 07, 2023

Shahab, S. W., Roggeveen, C. M., Sun, J., Kunhiraman, H., McSwain, L. F., Juraschka, K., Kumar, S. A., Saulnier, O., Taylor, M. D., Schniederjan, M., Schnepp, R. W., MacDonald, T. J., & Kenney, A. M. (2023). The <scp>LIN28B</scp>–let‐7–<scp>PBK</scp> pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology. Portico. https://doi.org/10.1002/1878-0261.13477

ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion

Nucleic Acids Research / May 01, 2021

Saulnier, O., Guedri-Idjouadiene, K., Aynaud, M.-M., Chakraborty, A., Bruyr, J., Pineau, J., O’Grady, T., Mirabeau, O., Grossetête, S., Galvan, B., Claes, M., Al Oula Hassoun, Z., Sadacca, B., Laud, K., Zaïdi, S., Surdez, D., Baulande, S., Rambout, X., Tirode, F., … Dequiedt, F. (2021). ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion. Nucleic Acids Research, 49(9), 5038–5056. https://doi.org/10.1093/nar/gkab305

ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin

Nucleic Acids Research / Jan 16, 2020

Tanaka, I., Chakraborty, A., Saulnier, O., Benoit-Pilven, C., Vacher, S., Labiod, D., Lam, E. W. F., Bièche, I., Delattre, O., Pouzoulet, F., Auboeuf, D., Vagner, S., & Dutertre, M. (2020). ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin. Nucleic Acids Research, 48(5), 2676–2693. https://doi.org/10.1093/nar/gkz1213

Gianfranco Santovito

Associate Professor of Physiology at the University of Padova
Most Relevant Research Interests
Genetics
Other Research Interests (75)
Fisiologia degli organismi acquatici
Microbiology
General Medicine
Molecular Biology
General Medicine
And 70 more
Most Relevant Publications (2+)

149 total publications

Cadmium metallothionein gene of Tetrahymena pyriformis

Gene / Jun 01, 1999

Piccinni, E., Bertaggia, D., Santovito, G., Miceli, C., & Kraev, A. (1999). Cadmium metallothionein gene of Tetrahymena pyriformis. Gene, 234(1), 51–59. https://doi.org/10.1016/s0378-1119(99)00181-x

The first transcriptomic resource for the Antarctic scallop Adamussium colbecki

Marine Genomics / Apr 01, 2019

Moro, G., Buonocore, F., Barucca, M., Spazzali, F., Canapa, A., Pallavicini, A., Scapigliati, G., & Gerdol, M. (2019). The first transcriptomic resource for the Antarctic scallop Adamussium colbecki. Marine Genomics, 44, 61–64. https://doi.org/10.1016/j.margen.2018.09.007

Sally Irwin

Professor of Genetics and the Microbiome at the University of Hawaii
Most Relevant Research Interests
Genetics
Other Research Interests (6)
Microbiome
Microbiology
Multidisciplinary
Molecular Biology
General Medicine
And 1 more
Most Relevant Publications (1+)

3 total publications

Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce

Genome / Oct 01, 1999

Irwin, S. V., Kesseli, R. V., Waycott, W., Ryder, E. J., Cho, J. J., & Michelmore, R. W. (1999). Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce. Genome, 42(5), 982–986. https://doi.org/10.1139/g99-055

Mehrdad Sheikhvatan

Iran University of Medical Sciences
Most Relevant Research Interests
Genetics
Other Research Interests (58)
Molecular Cardiogenetic
Obstetrics and Gynecology
Neurology (clinical)
Otorhinolaryngology
Gastroenterology
And 53 more
Most Relevant Publications (1+)

90 total publications

Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease

Iranian Journal of Biotechnology / Jun 01, 2019

Sheikhvatan, M., boroumand, M. A., Behmanesh, M., Ziaee, S., & Cheraghee, S. (2019). Integrin Beta-3 Gene Polymorphism and Risk for Myocardial Infarction in Premature Coronary Disease. Iranian Journal of Biotechnology, 17(2), 79–88. https://doi.org/10.21859/ijb.1921

Patrick G. Grant, Ph.D.

California
Multi Discipline Experience with Multiple Open Inovation Solutions
Most Relevant Research Interests
Genetics
Other Research Interests (42)
Multidisciplinary
General Agricultural and Biological Sciences
General Chemistry
Toxicology
Mechanical Engineering
And 37 more
Most Relevant Publications (2+)

41 total publications

Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2

Molecular Reproduction and Development / Jan 01, 2000

Bench, G., Corzett, M. H., Kramer, C. E., Grant, P. G., & Balhorn, R. (2000). Zinc is sufficiently abundant within mammalian sperm nuclei to bind stoichiometrically with protamine 2. Molecular Reproduction and Development, 56(4), 512–519. https://doi.org/10.1002/1098-2795(200008)56:4<512::aid-mrd9>3.0.co;2-m

Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae)

American Journal of Botany / Oct 01, 2001

Clark, B. M., St. Clair, L. L., Mangelson, N. F., Rees, L. B., Grant, P. G., & Bench, G. S. (2001). Characterization of mycobiont adaptations in the foliose lichen Xanthoparmelia chlorochroa (Parmeliaceae). American Journal of Botany, 88(10), 1742–1749. Portico. https://doi.org/10.2307/3558348

Patrick Reeson

University of Victoria
Most Relevant Research Interests
Genetics
Other Research Interests (18)
General Neuroscience
Cardiology and Cardiovascular Medicine
Neurology (clinical)
Neurology
General Immunology and Microbiology
And 13 more
Most Relevant Publications (2+)

11 total publications

Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex

Cell Reports Methods / Jun 01, 2023

Reeson, P., Boghozian, R., Cota, A. P., & Brown, C. E. (2023). Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex. Cell Reports Methods, 3(6), 100489. https://doi.org/10.1016/j.crmeth.2023.100489

Ultrastructural analysis of neurons, glia and capillaries in the peri‐infarct zone of an ischemic stroke

The FASEB Journal / Apr 01, 2013

Nahirney, P. C., Reeson, P., & Brown, C. E. (2013). Ultrastructural analysis of neurons, glia and capillaries in the peri‐infarct zone of an ischemic stroke. The FASEB Journal, 27(S1). Portico. https://doi.org/10.1096/fasebj.27.1_supplement.533.15

Chai Jin Lee

Seoul National University
Most Relevant Research Interests
Genetics
Genetics
Other Research Interests (11)
Bioinformatics
Network
Cancer
Cell Biology
Molecular Biology
And 6 more
Most Relevant Publications (3+)

8 total publications

Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer

BMC Medical Genomics / Feb 01, 2020

Lee, C.-J., Ahn, H., Jeong, D., Pak, M., Moon, J. H., & Kim, S. (2020). Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer. BMC Medical Genomics, 13(S3). https://doi.org/10.1186/s12920-020-0659-4

Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice

BMC Medical Genomics / Aug 01, 2016

Lee, C.-J., Ahn, H., Lee, S. B., Shin, J.-Y., Park, W.-Y., Kim, J.-I., Lee, J., Ryu, H., & Kim, S. (2016). Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice. BMC Medical Genomics, 9(S1). https://doi.org/10.1186/s12920-016-0195-4

StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis

BMC Genomics / Dec 01, 2019

Kang, D., Ahn, H., Lee, S., Lee, C.-J., Hur, J., Jung, W., & Kim, S. (2019). StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis. BMC Genomics, 20(S11). https://doi.org/10.1186/s12864-019-6283-z

Annabel Whibley

Bioinformatician at Bragato Research Institute based in Auckland, New Zealand.
Most Relevant Research Interests
Genetics
Other Research Interests (18)
Evolutionary Biology
Genomics
Multidisciplinary
General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
And 13 more
Most Relevant Publications (26+)

56 total publications

SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome

The American Journal of Human Genetics / Apr 01, 2008

Gilfillan, G. D., Selmer, K. K., Roxrud, I., Smith, R., Kyllerman, M., Eiklid, K., Kroken, M., Mattingsdal, M., Egeland, T., Stenmark, H., Sjøholm, H., Server, A., Samuelsson, L., Christianson, A., Tarpey, P., Whibley, A., Stratton, M. R., Futreal, P. A., Teague, J., … Strømme, P. (2008). SLC9A6 Mutations Cause X-Linked Mental Retardation, Microcephaly, Epilepsy, and Ataxia, a Phenotype Mimicking Angelman Syndrome. The American Journal of Human Genetics, 82(4), 1003–1010. https://doi.org/10.1016/j.ajhg.2008.01.013

Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation

The American Journal of Human Genetics / Feb 01, 2008

Froyen, G., Corbett, M., Vandewalle, J., Jarvela, I., Lawrence, O., Meldrum, C., Bauters, M., Govaerts, K., Vandeleur, L., Van Esch, H., Chelly, J., Sanlaville, D., van Bokhoven, H., Ropers, H.-H., Laumonnier, F., Ranieri, E., Schwartz, C. E., Abidi, F., Tarpey, P. S., … Gécz, J. (2008). Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation. The American Journal of Human Genetics, 82(2), 432–443. https://doi.org/10.1016/j.ajhg.2007.11.002

Fine-Scale Survey of X Chromosome Copy Number Variants and Indels Underlying Intellectual Disability

The American Journal of Human Genetics / Aug 01, 2010

Whibley, A. C., Plagnol, V., Tarpey, P. S., Abidi, F., Fullston, T., Choma, M. K., Boucher, C. A., Shepherd, L., Willatt, L., Parkin, G., Smith, R., Futreal, P. A., Shaw, M., Boyle, J., Licata, A., Skinner, C., Stevenson, R. E., Turner, G., Field, M., … Raymond, F. L. (2010). Fine-Scale Survey of X Chromosome Copy Number Variants and Indels Underlying Intellectual Disability. The American Journal of Human Genetics, 87(2), 173–188. https://doi.org/10.1016/j.ajhg.2010.06.017

Genetic architecture and balancing selection: the life and death of differentiated variants

Molecular Ecology / Mar 06, 2017

Llaurens, V., Whibley, A., & Joron, M. (2017). Genetic architecture and balancing selection: the life and death of differentiated variants. Molecular Ecology, 26(9), 2430–2448. Portico. https://doi.org/10.1111/mec.14051

CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes

European Journal of Human Genetics / Dec 23, 2009

Hackett, A., Tarpey, P. S., Licata, A., Cox, J., Whibley, A., Boyle, J., Rogers, C., Grigg, J., Partington, M., Stevenson, R. E., Tolmie, J., Yates, J. R., Turner, G., Wilson, M., Futreal, A. P., Corbett, M., Shaw, M., Gecz, J., Raymond, F. L., … Abidi, F. E. (2009). CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes. European Journal of Human Genetics, 18(5), 544–552. https://doi.org/10.1038/ejhg.2009.220

Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms

Nature Genetics / Jan 25, 2021

Jay, P., Chouteau, M., Whibley, A., Bastide, H., Parrinello, H., Llaurens, V., & Joron, M. (2021). Mutation load at a mimicry supergene sheds new light on the evolution of inversion polymorphisms. Nature Genetics, 53(3), 288–293. https://doi.org/10.1038/s41588-020-00771-1

Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks

Human Molecular Genetics / Jan 11, 2010

Kerzendorfer, C., Whibley, A., Carpenter, G., Outwin, E., Chiang, S.-C., Turner, G., Schwartz, C., El-Khamisy, S., Raymond, F. L., & O’Driscoll, M. (2010). Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks. Human Molecular Genetics, 19(7), 1324–1334. https://doi.org/10.1093/hmg/ddq008

Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies

Heredity / Mar 25, 2015

Huber, B., Whibley, A., Poul, Y. L., Navarro, N., Martin, A., Baxter, S., Shah, A., Gilles, B., Wirth, T., McMillan, W. O., & Joron, M. (2015). Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity, 114(5), 515–524. https://doi.org/10.1038/hdy.2015.22

Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movements

European Journal of Human Genetics / May 19, 2010

Whibley, A., Urquhart, J., Dore, J., Willatt, L., Parkin, G., Gaunt, L., Black, G., Donnai, D., & Raymond, F. L. (2010). Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movements. European Journal of Human Genetics, 18(10), 1095–1099. https://doi.org/10.1038/ejhg.2010.41

Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads

Heredity / Oct 01, 2014

Gouin, A., Legeai, F., Nouhaud, P., Whibley, A., Simon, J.-C., & Lemaitre, C. (2014). Whole-genome re-sequencing of non-model organisms: lessons from unmapped reads. Heredity, 114(5), 494–501. https://doi.org/10.1038/hdy.2014.85

The changing face of genome assemblies: Guidance on achieving high‐quality reference genomes

Molecular Ecology Resources / Jan 20, 2021

Whibley, A., Kelley, J. L., & Narum, S. R. (2021). The changing face of genome assemblies: Guidance on achieving high‐quality reference genomes. Molecular Ecology Resources, 21(3), 641–652. Portico. https://doi.org/10.1111/1755-0998.13312

Lessons learnt from large-scale exon re-sequencing of the X chromosome

Human Molecular Genetics / Apr 15, 2009

Raymond, F. L., Whibley, A., Stratton, M. R., & Gecz, J. (2009). Lessons learnt from large-scale exon re-sequencing of the X chromosome. Human Molecular Genetics, 18(R1), R60–R64. https://doi.org/10.1093/hmg/ddp071

WING SHAPE VARIATION ASSOCIATED WITH MIMICRY IN BUTTERFLIES

Evolution / Apr 24, 2013

Jones, R. T., Poul, Y. L., Whibley, A. C., Mérot, C., ffrench-Constant, R. H., & Joron, M. (2013). WING SHAPE VARIATION ASSOCIATED WITH MIMICRY IN BUTTERFLIES. Evolution, 67(8), 2323–2334. https://doi.org/10.1111/evo.12114

Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi

Molecular Ecology / Jul 26, 2021

Duntsch, L., Whibley, A., Brekke, P., Ewen, J. G., & Santure, A. W. (2021). Genomic data of different resolutions reveal consistent inbreeding estimates but contrasting homozygosity landscapes for the threatened Aotearoa New Zealand hihi. Molecular Ecology, 30(23), 6006–6020. Portico. https://doi.org/10.1111/mec.16068

Sharing and reporting benefits from biodiversity research

Molecular Ecology / Nov 06, 2020

Marden, E., Abbott, R. J., Austerlitz, F., Ortiz‐Barrientos, D., Baucom, R. S., Bongaerts, P., Bonin, A., Bonneaud, C., Browne, L., Alex Buerkle, C., Caicedo, A. L., Coltman, D. W., Cruzan, M. B., Davison, A., DeWoody, J. A., Dumbrell, A. J., Emerson, B. C., Fountain‐Jones, N. M., Gillespie, R., … Rieseberg, L. H. (2020). Sharing and reporting benefits from biodiversity research. Molecular Ecology, 30(5), 1103–1107. Portico. https://doi.org/10.1111/mec.15702

Contrasting genomic and phenotypic outcomes of hybridization between pairs of mimetic butterfly taxa across a suture zone

Molecular Ecology / Apr 01, 2020

Gauthier, J., de Silva, D. L., Gompert, Z., Whibley, A., Houssin, C., Le Poul, Y., McClure, M., Lemaitre, C., Legeai, F., Mallet, J., & Elias, M. (2020). Contrasting genomic and phenotypic outcomes of hybridization between pairs of mimetic butterfly taxa across a suture zone. Molecular Ecology, 29(7), 1328–1343. Portico. https://doi.org/10.1111/mec.15403

Recurrent deletion ofZNF630at Xp11.23 is not associated with mental retardation

American Journal of Medical Genetics Part A / Mar 01, 2010

Lugtenberg, D., Zangrande-Vieira, L., Kirchhoff, M., Whibley, A. C., Oudakker, A. R., Kjaergaard, S., Vianna-Morgante, A. M., Kleefstra, T., Ruiter, M., Jehee, F. S., Ullmann, R., Schwartz, C. E., Stratton, M., Raymond, F. L., Veltman, J. A., Vrijenhoek, T., Pfundt, R., Schuurs-Hoeijmakers, J. H. M., Hehir-Kwa, J. Y., … de Brouwer, A. P. M. (2010). Recurrent deletion ofZNF630at Xp11.23 is not associated with mental retardation. American Journal of Medical Genetics Part A, 152A(3), 638–645. https://doi.org/10.1002/ajmg.a.33292

The design and application of a 50 K SNP chip for a threatened Aotearoa New Zealand passerine, the hihi

Molecular Ecology Resources / Aug 07, 2021

Lee, K. D., Millar, C. D., Brekke, P., Whibley, A., Ewen, J. G., Hingston, M., Zhu, A., & Santure, A. W. (2021). The design and application of a 50 K SNP chip for a threatened Aotearoa New Zealand passerine, the hihi. Molecular Ecology Resources, 22(1), 415–429. Portico. https://doi.org/10.1111/1755-0998.13480

Genomic signatures of inbreeding depression for a threatened Aotearoa New Zealand passerine

Molecular Ecology / Feb 05, 2023

Duntsch, L., Whibley, A., de Villemereuil, P., Brekke, P., Bailey, S., Ewen, J. G., & Santure, A. W. (2023). Genomic signatures of inbreeding depression for a threatened Aotearoa New Zealand passerine. Molecular Ecology, 32(8), 1893–1907. Portico. https://doi.org/10.1111/mec.16855

Assembly of female and male hihi genomes (stitchbird; Notiomystis cincta) enables characterization of the W chromosome and resources for conservation genomics

Molecular Ecology Resources / Jun 18, 2023

Bailey, S., Guhlin, J., Senanayake, D. S., Scherer, P., Brekke, P., Ewen, J. G., Santure, A. W., & Whibley, A. (2023). Assembly of female and male hihi genomes (stitchbird; Notiomystis cincta) enables characterization of the W chromosome and resources for conservation genomics. Molecular Ecology Resources. Portico. https://doi.org/10.1111/1755-0998.13823

Tracing the introduction of the invasive common myna using population genomics

Heredity / May 17, 2023

Atsawawaranunt, K., Ewart, K. M., Major, R. E., Johnson, R. N., Santure, A. W., & Whibley, A. (2023). Tracing the introduction of the invasive common myna using population genomics. Heredity, 131(1), 56–67. https://doi.org/10.1038/s41437-023-00621-w

MtING2 encodes an ING domain PHD finger protein which affects Medicago growth, flowering, global patterns of H3K4me3, and gene expression

The Plant Journal / Oct 17, 2022

Jaudal, M., Mayo‐Smith, M., Poulet, A., Whibley, A., Peng, Y., Zhang, L., Thomson, G., Trimborn, L., Jacob, Y., van Wolfswinkel, J. C., Goldstone, D. C., Wen, J., Mysore, K. S., & Putterill, J. (2022). <scp>MtING2</scp> encodes an <scp>ING</scp> domain <scp>PHD</scp> finger protein which affects Medicago growth, flowering, global patterns of <scp>H3K4me3</scp>, and gene expression. The Plant Journal, 112(4), 1029–1050. Portico. https://doi.org/10.1111/tpj.15994

Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies

Molecular Biology and Evolution / Jul 01, 2023

Rougemont, Q., Huber, B., Martin, S. H., Whibley, A., Estrada, C., Solano, D., Orpet, R., McMillan, W. O., Frérot, B., & Joron, M. (2023). Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies. Molecular Biology and Evolution, 40(7). https://doi.org/10.1093/molbev/msad166

First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies

Molecular Ecology Resources / Jan 27, 2023

Gauthier, J., Meier, J., Legeai, F., McClure, M., Whibley, A., Bretaudeau, A., Boulain, H., Parrinello, H., Mugford, S. T., Durbin, R., Zhou, C., McCarthy, S., Wheat, C. W., Piron‐Prunier, F., Monsempes, C., François, M., Jay, P., Noûs, C., Persyn, E., … Elias, M. (2023). First chromosome scale genomes of ithomiine butterflies (Nymphalidae: Ithomiini): Comparative models for mimicry genetic studies. Molecular Ecology Resources, 23(4), 872–885. Portico. https://doi.org/10.1111/1755-0998.13749

Genome insights give cause for optimism in the ongoing battle to save the vaquita

Molecular Ecology Resources / Feb 22, 2021

Whibley, A. (2021). Genome insights give cause for optimism in the ongoing battle to save the vaquita. Molecular Ecology Resources, 21(4), 1005–1007. Portico. https://doi.org/10.1111/1755-0998.13345

Stripes, sex and sparrows: what processes underlie heteromorphic chromosome evolution?

Heredity / Aug 18, 2010

Joron, M., & Whibley, A. (2010). Stripes, sex and sparrows: what processes underlie heteromorphic chromosome evolution? Heredity, 106(4), 531–532. https://doi.org/10.1038/hdy.2010.106

Matheus Ferraz

PhD in computational chemistry, bioinformatician with experience in industry
Most Relevant Research Interests
Genetics
Other Research Interests (35)
Computational Chemistry
Protein Design
Machine Learning
Virology
Microbiology
And 30 more
Most Relevant Publications (1+)

17 total publications

Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil

Microbiology Spectrum / Feb 23, 2022

Naveca, F. G., Nascimento, V., Souza, V., Corado, A. de L., Nascimento, F., Silva, G., Mejía, M. C., Brandão, M. J., Costa, Á., Duarte, D., Pessoa, K., Jesus, M., Gonçalves, L., Fernandes, C., Mattos, T., Abdalla, L., Santos, J. H., Martins, A., Chui, F. M., … Bello, G. (2022). Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil. Microbiology Spectrum, 10(1). https://doi.org/10.1128/spectrum.02366-21

Ernesto Lowy

Senior Bioinformatician specialised in Cancer Genomics
Most Relevant Research Interests
Genetics
Other Research Interests (28)
Data analysis
Data science
Bioinformatics
Genomics
Multidisciplinary
And 23 more
Most Relevant Publications (4+)

67 total publications

VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases

Nucleic Acids Research / Dec 15, 2014

Giraldo-Calderón, G. I., Emrich, S. J., MacCallum, R. M., Maslen, G., Dialynas, E., Topalis, P., Ho, N., Gesing, S., Madey, G., Collins, F. H., & Lawson, D. (2014). VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases. Nucleic Acids Research, 43(D1), D707–D713. https://doi.org/10.1093/nar/gku1117

Ensembl Genomes 2016: more genomes, more complexity

Nucleic Acids Research / Nov 17, 2015

Kersey, P. J., Allen, J. E., Armean, I., Boddu, S., Bolt, B. J., Carvalho-Silva, D., Christensen, M., Davis, P., Falin, L. J., Grabmueller, C., Humphrey, J., Kerhornou, A., Khobova, J., Aranganathan, N. K., Langridge, N., Lowy, E., McDowall, M. D., Maheswari, U., Nuhn, M., … Staines, D. M. (2015). Ensembl Genomes 2016: more genomes, more complexity. Nucleic Acids Research, 44(D1), D574–D580. https://doi.org/10.1093/nar/gkv1209

HLA Genes in the Chuvashian Population from European Russia: Admixture of Central European and Mediterranean Populations

Human Biology / Jan 01, 2003

Arnaiz-Villena, A., Martinez-Laso, J., Moscoso, J., Livshits, G., Zamora, J., Gomez-Casado, E., Silvera-Redondo, C., Melvin, K., & Crawford, M. H. (2003). HLA Genes in the Chuvashian Population from European Russia: Admixture of Central European and Mediterranean Populations. Human Biology, 75(3), 375–392. https://doi.org/10.1353/hub.2003.0040

HLA molecular markers in Tuvinians: a population with both Oriental and Caucasoid characteristics

Annals of Human Genetics / May 01, 2001

MARTINEZ-LASO, J., SARTAKOVA, M., ALLENDE, L., KONENKOV, V., MOSCOSO, J., SILVERA-REDONDO, C., PACHO, A., TRAPAGA, J., GOMEZ-CASADO, E., & ARNAIZ-VILLENA, A. (2001). HLA molecular markers in Tuvinians: a population with both Oriental and Caucasoid characteristics. Annals of Human Genetics, 65(3), 245–261. https://doi.org/10.1046/j.1469-1809.2001.6530245.x

Niko Popitsch

Senior Bioinformatician, University of Vienna
Most Relevant Research Interests
Genetics
Other Research Interests (14)
Bioinformatics
Genetics (clinical)
General Physics and Astronomy
General Biochemistry, Genetics and Molecular Biology
General Chemistry
And 9 more
Most Relevant Publications (3+)

73 total publications

The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

PLOS Pathogens / Sep 15, 2015

Drecktrah, D., Lybecker, M., Popitsch, N., Rescheneder, P., Hall, L. S., & Samuels, D. S. (2015). The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation. PLOS Pathogens, 11(9), e1005160. https://doi.org/10.1371/journal.ppat.1005160

Mutations inPIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies

Human Molecular Genetics / Aug 20, 2015

Ilkovski, B., Pagnamenta, A. T., O’Grady, G. L., Kinoshita, T., Howard, M. F., Lek, M., Thomas, B., Turner, A., Christodoulou, J., Sillence, D., Knight, S. J. L., Popitsch, N., Keays, D. A., Anzilotti, C., Goriely, A., Waddell, L. B., Brilot, F., North, K. N., Kanzawa, N., … Clarke, N. F. (2015). Mutations inPIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies. Human Molecular Genetics, 24(21), 6146–6159. https://doi.org/10.1093/hmg/ddv331

Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders

European Journal of Human Genetics / Mar 22, 2017

Pagnamenta, A. T., Murakami, Y., Taylor, J. M., Anzilotti, C., Howard, M. F., Miller, V., Johnson, D. S., Tadros, S., Mansour, S., Temple, I. K., Firth, R., Rosser, E., Harrison, R. E., Kerr, B., Popitsch, N., Kinoshita, T., Taylor, J. C., & Kini, U. (2017). Analysis of exome data for 4293 trios suggests GPI-anchor biogenesis defects are a rare cause of developmental disorders. European Journal of Human Genetics, 25(6), 669–679. https://doi.org/10.1038/ejhg.2017.32

John Joe

Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Most Relevant Research Interests
genetics
Genetics
Other Research Interests (72)
microbiology
systems biology
quantum biology
Management of Technology and Innovation
General Medicine
And 67 more
Most Relevant Publications (4+)

95 total publications

Sequence and characteristics or IS900, an insertion element identified in a human Crohn's disease isolate orMycobacterium paratuberculosis

Nucleic Acids Research / Jan 01, 1989

Green, E. P., Tizard, M. L. V., Moss, M. T., Thompson, J., Winterbourne, D. J., McFadden, J. J., & Hermon-Taylor, J. (1989). Sequence and characteristics or IS900, an insertion element identified in a human Crohn’s disease isolate orMycobacterium paratuberculosis. Nucleic Acids Research, 17(22), 9063–9073. https://doi.org/10.1093/nar/17.22.9063

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

PLoS Pathogens / Jul 21, 2011

Beste, D. J. V., Bonde, B., Hawkins, N., Ward, J. L., Beale, M. H., Noack, S., Nöh, K., Kruger, N. J., Ratcliffe, R. G., & McFadden, J. (2011). 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation. PLoS Pathogens, 7(7), e1002091. https://doi.org/10.1371/journal.ppat.1002091

Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis

PLoS Computational Biology / Jun 30, 2011

Bonde, B. K., Beste, D. J. V., Laing, E., Kierzek, A. M., & McFadden, J. (2011). Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis. PLoS Computational Biology, 7(6), e1002060. https://doi.org/10.1371/journal.pcbi.1002060

Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

BMC Genomics / May 28, 2019

Mendum, T. A., Chandran, A., Williams, K., Vordermeier, H. M., Villarreal-Ramos, B., Wu, H., Singh, A., Smith, A. A., Butler, R. E., Prasad, A., Bharti, N., Banerjee, R., Kasibhatla, S. M., Bhatt, A., Stewart, G. R., & McFadden, J. (2019). Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle. BMC Genomics, 20(1). https://doi.org/10.1186/s12864-019-5791-1

Nicolas Collao

University of Ottawa
Most Relevant Research Interests
Genetics
Other Research Interests (19)
Stem cells
Exercise Physiology
Cellular Biology
Immunology
Immunology and Allergy
And 14 more
Most Relevant Publications (1+)

12 total publications

Muscle injury induces a transient senescence‐like state that is required for myofiber growth during muscle regeneration

The FASEB Journal / Oct 03, 2022

Young, L. V., Wakelin, G., Cameron, A. W. R., Springer, S. A., Ross, J. P., Wolters, G., Murphy, J. P., Arsenault, M. G., Ng, S., Collao, N., De Lisio, M., Ljubicic, V., & Johnston, A. P. W. (2022). Muscle injury induces a transient senescence‐like state that is required for myofiber growth during muscle regeneration. The FASEB Journal, 36(11). Portico. https://doi.org/10.1096/fj.202200289rr

Anna Koster

Most Relevant Research Interests
Genetics
Other Research Interests (11)
Multidisciplinary
Computational Theory and Mathematics
Multidisciplinary
Cellular and Molecular Neuroscience
Molecular Biology
And 6 more
Most Relevant Publications (1+)

4 total publications

Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating

PLOS Computational Biology / Mar 30, 2020

McKiernan, K. A., Koster, A. K., Maduke, M., & Pande, V. S. (2020). Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating. PLOS Computational Biology, 16(3), e1007530. https://doi.org/10.1371/journal.pcbi.1007530

Example genetics projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on genetics?

Genetic Testing for Personalized Medicine

A pharmaceutical company can collaborate with a genetics researcher to develop genetic tests that predict individual responses to medications. This can help optimize treatment plans and improve patient outcomes.

Crop Improvement through Genetic Engineering

An agricultural company can partner with a genetics expert to enhance crop traits through genetic engineering. This can lead to improved yields, disease resistance, and nutritional value.

Genomic Data Analysis for Precision Agriculture

A technology company can work with a genetics researcher to analyze genomic data and provide insights for precision agriculture. This can optimize resource allocation, improve crop management, and reduce environmental impact.

Genetic Counseling Services

A healthcare company can collaborate with a genetics specialist to offer genetic counseling services. This can help individuals understand their genetic risks, make informed decisions, and manage their health proactively.

Drug Discovery and Target Identification

A biotechnology company can partner with a genetics researcher to identify potential drug targets based on genetic insights. This can accelerate the discovery and development of novel therapeutics.