Work with thought leaders and academic experts in immunology
Companies can greatly benefit from working with experts in the field of Immunology. These researchers can provide valuable insights and expertise to enhance research and development efforts. They can help in the development of new drugs and therapies, conduct preclinical and clinical trials, and provide guidance on regulatory compliance. Additionally, Immunology experts can contribute to the understanding of disease mechanisms, identify potential biomarkers, and develop diagnostic tools. Their knowledge can also be applied in the fields of personalized medicine, immunotherapy, and vaccine development. Collaborating with Immunology researchers can lead to breakthrough discoveries, improved patient outcomes, and a competitive advantage in the healthcare industry.
Researchers on NotedSource with backgrounds in immunology include Regan Hamel, Michael W Harman, Ping Luo, Susan Song, MD/PhD, Boris Leibovitch, Mohammad Imran Khan, Dr. Justin Whalley, Ph.D, Rosani Matoso Silva, Ph.D., Lindsay Webb, PhD, Jeffrey Townsend, and Katie Barr.
Regan Hamel
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
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Most Relevant Publications (2+)
12 total publications
Metabolic Control of Smoldering Neuroinflammation
Frontiers in Immunology / Jun 23, 2021
Peruzzotti-Jametti, L., Willis, C. M., Hamel, R., Krzak, G., & Pluchino, S. (2021). Metabolic Control of Smoldering Neuroinflammation. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.705920
Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury
Frontiers in Immunology / Aug 24, 2022
Yao, X.-Q., Chen, J.-Y., Yu, Z.-H., Huang, Z.-C., Hamel, R., Zeng, Y.-Q., Huang, Z.-P., Tu, K.-W., Liu, J.-H., Lu, Y.-M., Zhou, Z.-T., Pluchino, S., Zhu, Q.-A., & Chen, J.-T. (2022). Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.964138
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Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
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15 total publications
The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks
Infection and Immunity / Aug 01, 2011
Caimano, M. J., Kenedy, M. R., Kairu, T., Desrosiers, D. C., Harman, M., Dunham-Ems, S., Akins, D. R., Pal, U., & Radolf, J. D. (2011). The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks. Infection and Immunity, 79(8), 3117–3130. https://doi.org/10.1128/iai.05136-11
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Ping Luo
Bioinformatics Specialist at Princess Margaret Cancer Centre with experience in deep learning
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23 total publications
Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma
Blood / Nov 05, 2021
Coffey, D. G., Maura, F., Gonzalez-Kozlova, E., Diaz-Mejia3, J., Luo, P., Zhang, Y., Xu, Y., Warren, E. H., Smith, E. L., Cho, H. J., Lesokhin, A., Diamond, B., Kazandjian, D., Pugh, T. J., Green, D. J., Gnjatic, S., & Landgren, O. (2021). Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma. Blood, 138(Supplement 1), 329–329. https://doi.org/10.1182/blood-2021-154506
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Susan Song, MD/PhD
Research Assistant Professor in Neuroscience at University of Pittsburgh
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Most Relevant Publications (2+)
20 total publications
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function
Journal of Neuroinflammation / Aug 28, 2021
Liu, Q., Bhuiyan, M. I. H., Liu, R., Song, S., Begum, G., Young, C. B., Foley, L. M., Chen, F., Hitchens, T. K., Cao, G., Chattopadhyay, A., He, L., & Sun, D. (2021). Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02234-8
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury
Journal of Neuroinflammation / Oct 05, 2022
Song, S., Hasan, M. N., Yu, L., Paruchuri, S. S., Bielanin, J. P., Metwally, S., Oft, H. C. M., Fischer, S. G., Fiesler, V. M., Sen, T., Gupta, R. K., Foley, L. M., Hitchens, T. K., Dixon, C. E., Cambi, F., Sen, N., & Sun, D. (2022). Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. Journal of Neuroinflammation, 19(1). https://doi.org/10.1186/s12974-022-02608-6
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Boris Leibovitch
Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia
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Other Research Interests (8)
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22 total publications
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
Blood / Mar 15, 2008
Marango, J., Shimoyama, M., Nishio, H., Meyer, J. A., Min, D.-J., Sirulnik, A., Martinez-Martinez, Y., Chesi, M., Bergsagel, P. L., Zhou, M.-M., Waxman, S., Leibovitch, B. A., Walsh, M. J., & Licht, J. D. (2008). The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood, 111(6), 3145–3154. https://doi.org/10.1182/blood-2007-06-092122
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Mohammad Imran Khan
Postdoctoral Associate at University of Maryland College Park in the Department of Nutrition and Food Science
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Other Research Interests (22)
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11 total publications
Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency
Medical Microbiology and Immunology / Oct 05, 2018
Khan, Md. I., Behera, S. K., Paul, P., Das, B., Suar, M., Jayabalan, R., Fawcett, D., Poinern, G. E. J., Tripathy, S. K., & Mishra, A. (2018). Biogenic Au@ZnO core–shell nanocomposites kill Staphylococcus aureus without provoking nuclear damage and cytotoxicity in mouse fibroblasts cells under hyperglycemic condition with enhanced wound healing proficiency. Medical Microbiology and Immunology, 208(5), 609–629. https://doi.org/10.1007/s00430-018-0564-z
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Rosani Matoso Silva, Ph.D.
Fulbrigther Humphrey Fellow 2023-2024 from Brazil
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Other Research Interests (7)
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Most Relevant Publications (1+)
16 total publications
Anaphylaxis to lipid transfer protein from sunflower seeds
Allergy / Sep 07, 2010
Yagami, A. (2010). Anaphylaxis to lipid transfer protein from sunflower seeds. Allergy, 65(10), 1340–1341. Portico. https://doi.org/10.1111/j.1398-9995.2010.02337.x
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Lindsay Webb, PhD
Immunologist and cancer biologist passionate about driving innovative research to improve patient health
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Other Research Interests (6)
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Most Relevant Publications (7+)
11 total publications
203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells
Journal for ImmunoTherapy of Cancer / Nov 01, 2021
Ding, J., Webb, L., Patterson, T., Fleury, M., Zieba, A., Horton, H., Hofmeister, R., Gutierrez, D., & Tighe, R. (2021). 203 A membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence and efficacy of CD70-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A214–A214. https://doi.org/10.1136/jitc-2021-sitc2021.203
173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells
Journal for ImmunoTherapy of Cancer / Nov 01, 2021
Fleury, M., McCarthy, D., Horton, H., Anderson, C., Watt, A., Zieba, A., Webb, L., Ding, J., Tighe, R., Hofmeister, R., & Gutierrez, D. (2021). 173 Expression of a membrane-tethered IL-15/IL-15 receptor fusion protein enhances the persistence of MSLN-targeted TRuC-T cells. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A185–A185. https://doi.org/10.1136/jitc-2021-sitc2021.173
M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation
Cancer Immunology Research / Dec 13, 2023
Xu, C., Zhou, X., Webb, L., Yalavarthi, S., Zheng, W., Saha, S., Schweickhardt, R., Soloviev, M., Jenkins, M. H., Brandstetter, S., Belousova, N., Alimzhanov, M., Rabinovich, B., Deshpande, A. M., Brewis, N., & Helming, L. (2023). M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation. Cancer Immunology Research, 12(2), 195–213. https://doi.org/10.1158/2326-6066.cir-23-0243
Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models
Cancer Immunology Research / Jan 01, 2022
Xu, C., Webb, L., Yalavarthi, S., Bourin, C., & Moisan, J. (2022). Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models. Cancer Immunology Research, 10(1_Supplement), P077–P077. https://doi.org/10.1158/2326-6074.tumimm21-p077
757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity
Journal for ImmunoTherapy of Cancer / Nov 01, 2021
Xu, C., Rabinovich, B., Deshpande, A., Zhou, X., Pipp, F. C., Schweickhardt, R., Webb, L., Yalavarthi, S., Bourin, C., Ghatak, P., Safi, B., Wollerton, F., Brewis, N., Munoz-Olaya, J., Belousova, N., Alimzhanov, M., Hubensack, M., Halle, J.-P., Blaukat, A., & Moisan, J. (2021). 757 M9657, a novel tumor-targeted conditional anti-CD137 agonist displays MSLN-dependent anti-tumor immunity. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A792–A792. https://doi.org/10.1136/jitc-2021-sitc2021.757
NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms
Frontiers in Immunology / Mar 19, 2019
Webb, L. M., Narvaez Miranda, J., Amici, S. A., Sengupta, S., Nagy, G., & Guerau-de-Arellano, M. (2019). NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms. Frontiers in Immunology, 10. https://doi.org/10.3389/fimmu.2019.00524
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis
The Journal of Immunology / Feb 15, 2017
Webb, L. M., Amici, S. A., Jablonski, K. A., Savardekar, H., Panfil, A. R., Li, L., Zhou, W., Peine, K., Karkhanis, V., Bachelder, E. M., Ainslie, K. M., Green, P. L., Li, C., Baiocchi, R. A., & Guerau-de-Arellano, M. (2017). PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis. The Journal of Immunology, 198(4), 1439–1451. https://doi.org/10.4049/jimmunol.1601702
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Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
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207 total publications
Potential effectiveness of long-acting injectable pre-exposure prophylaxis for HIV prevention in men who have sex with men: a modelling study
The Lancet HIV / Sep 01, 2018
Marshall, B. D. L., Goedel, W. C., King, M. R. F., Singleton, A., Durham, D. P., Chan, P. A., Townsend, J. P., & Galvani, A. P. (2018). Potential effectiveness of long-acting injectable pre-exposure prophylaxis for HIV prevention in men who have sex with men: a modelling study. The Lancet HIV, 5(9), e498–e505. https://doi.org/10.1016/s2352-3018(18)30097-3
Modelling microbial infection to address global health challenges
Nature Microbiology / Sep 20, 2019
Fitzpatrick, M. C., Bauch, C. T., Townsend, J. P., & Galvani, A. P. (2019). Modelling microbial infection to address global health challenges. Nature Microbiology, 4(10), 1612–1619. https://doi.org/10.1038/s41564-019-0565-8
The critical importance of retention in HIV prevention
The Lancet HIV / Sep 01, 2018
Golub, S. A., & Enemchukwu, C. U. (2018). The critical importance of retention in HIV prevention. The Lancet HIV, 5(9), e475–e476. https://doi.org/10.1016/s2352-3018(18)30130-9
Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel
Frontiers in Cellular and Infection Microbiology / Jun 19, 2018
Santos, L. A., Adhikarla, H., Yan, X., Wang, Z., Fouts, D. E., Vinetz, J. M., Alcantara, L. C. J., Hartskeerl, R. A., Goris, M. G. A., Picardeau, M., Reis, M. G., Townsend, J. P., Zhao, H., Ko, A. I., & Wunder, E. A. (2018). Genomic Comparison Among Global Isolates of L. interrogans Serovars Copenhageni and Icterohaemorrhagiae Identified Natural Genetic Variation Caused by an Indel. Frontiers in Cellular and Infection Microbiology, 8. https://doi.org/10.3389/fcimb.2018.00193
Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira
Frontiers in Cellular and Infection Microbiology / Feb 23, 2018
Adhikarla, H., Wunder, E. A., Mechaly, A. E., Mehta, S., Wang, Z., Santos, L., Bisht, V., Diggle, P., Murray, G., Adler, B., Lopez, F., Townsend, J. P., Groisman, E., Picardeau, M., Buschiazzo, A., & Ko, A. I. (2018). Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira. Frontiers in Cellular and Infection Microbiology, 8. https://doi.org/10.3389/fcimb.2018.00045
Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
PLoS Pathogens / May 08, 2014
Talbert-Slagle, K., Atkins, K. E., Yan, K.-K., Khurana, E., Gerstein, M., Bradley, E. H., Berg, D., Galvani, A. P., & Townsend, J. P. (2014). Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body. PLoS Pathogens, 10(5), e1004092. https://doi.org/10.1371/journal.ppat.1004092
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Example immunology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on immunology?
Development of Novel Immunotherapies
An Immunology expert can collaborate with a pharmaceutical company to develop novel immunotherapies for the treatment of cancer and autoimmune diseases. Their expertise in understanding the immune system and its response to diseases can help in identifying new targets and designing effective therapies.
Drug Discovery and Development
Companies can collaborate with Immunology researchers to discover and develop new drugs. These experts can provide insights into disease mechanisms, identify potential drug targets, and evaluate the efficacy and safety of drug candidates through preclinical and clinical trials.
Biomarker Identification
Immunology experts can assist companies in identifying biomarkers that can be used for disease diagnosis, prognosis, and monitoring. These biomarkers can help in early detection, personalized treatment approaches, and assessing treatment response.
Vaccine Development
Collaborating with Immunology researchers can accelerate the development of vaccines. Their knowledge of immune responses to pathogens can aid in the design and optimization of vaccines, ensuring their effectiveness and safety.
Personalized Medicine
Immunology experts can contribute to the field of personalized medicine by understanding individual variations in immune responses. This knowledge can help in tailoring treatment approaches based on a patient's immune profile, leading to improved therapeutic outcomes.