Work with thought leaders and academic experts in structural biology
Companies can greatly benefit from collaborating with academic researchers in the field of Structural Biology. These experts can provide valuable insights and expertise in understanding the structure and function of biological molecules. Here are some ways companies can collaborate with them: 1. Drug Discovery and Development: Structural biologists can help in identifying potential drug targets and designing new drugs by studying the structure of target molecules. 2. Protein Engineering: They can assist in modifying and optimizing proteins for various applications, such as enzyme engineering, biocatalysis, and protein therapeutics. 3. Biomolecular Interactions: Structural biologists can investigate the interactions between proteins, nucleic acids, and other biomolecules, providing insights into molecular recognition and signaling pathways. 4. Structural Analysis: They can determine the three-dimensional structures of biomolecules using techniques like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy. 5. Biotechnology and Biomedical Research: Collaborating with structural biologists can enhance research in areas like protein engineering, drug delivery systems, and understanding disease mechanisms. By partnering with academic researchers in Structural Biology, companies can leverage their expertise to drive innovation, develop new products, and stay ahead in the competitive market.
Experts on NotedSource with backgrounds in structural biology include Aimee Eggler, Ammon Posey, Jeffrey Townsend, basanti deopura, Ping Luo, Emily Owens, Sumeet K. Tiwari, Asst. Prof. Eng. Davide Verzotto, Ph.D., Jonathan Moore, David Studholme, Nitin Pandey, Dr. Susanne Ressl, and Matheus Ferraz.
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
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Other Research Interests (26)
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Most Relevant Publications (1+)
25 total publications
Sites of alkylation of human Keap1 by natural chemoprevention agents
Journal of the American Society for Mass Spectrometry / Dec 01, 2007
Luo, Y., Eggler, A. L., Liu, D., Liu, G., Mesecar, A. D., & van Breemen, R. B. (2007). Sites of alkylation of human Keap1 by natural chemoprevention agents. Journal of the American Society for Mass Spectrometry, 18(12), 2226–2232. https://doi.org/10.1016/j.jasms.2007.09.015
Ammon Posey
Research Scientist, Washington University in St. Louis
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Other Research Interests (21)
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Most Relevant Publications (1+)
49 total publications
Mechanistic Inferences From Analysis of Measurements of Protein Phase Transitions in Live Cells
Journal of Molecular Biology / Jun 01, 2021
Posey, A. E., Ruff, K. M., Lalmansingh, J. M., Kandola, T. S., Lange, J. J., Halfmann, R., & Pappu, R. V. (2021). Mechanistic Inferences From Analysis of Measurements of Protein Phase Transitions in Live Cells. Journal of Molecular Biology, 433(12), 166848. https://doi.org/10.1016/j.jmb.2021.166848
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
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Other Research Interests (71)
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207 total publications
Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance
BMC Bioinformatics / Mar 22, 2012
Zhang, Z., Li, J., Cui, P., Ding, F., Li, A., Townsend, J. P., & Yu, J. (2012). Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance. BMC Bioinformatics, 13(1). https://doi.org/10.1186/1471-2105-13-43
basanti deopura
Academic &consultant in man made fibers, Many Technology ready for industries
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Other Research Interests (45)
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Most Relevant Publications (1+)
89 total publications
Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents
International Journal of Biological Macromolecules / Jan 01, 2016
Tummalapalli, M., Berthet, M., Verrier, B., Deopura, B. L., Alam, M. S., & Gupta, B. (2016). Composite wound dressings of pectin and gelatin with aloe vera and curcumin as bioactive agents. International Journal of Biological Macromolecules, 82, 104–113. https://doi.org/10.1016/j.ijbiomac.2015.10.087
Ping Luo
Postdoctoral Researcher at Princess Margaret Cancer Centre with experience in deep learning
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Other Research Interests (24)
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Most Relevant Publications (3+)
23 total publications
Identifying cell types from single-cell data based on similarities and dissimilarities between cells
BMC Bioinformatics / May 01, 2021
Li, Y., Luo, P., Lu, Y., & Wu, F.-X. (2021). Identifying cell types from single-cell data based on similarities and dissimilarities between cells. BMC Bioinformatics, 22(S3). https://doi.org/10.1186/s12859-020-03873-z
Ensemble disease gene prediction by clinical sample-based networks
BMC Bioinformatics / Mar 01, 2020
Luo, P., Tian, L.-P., Chen, B., Xiao, Q., & Wu, F.-X. (2020). Ensemble disease gene prediction by clinical sample-based networks. BMC Bioinformatics, 21(S2). https://doi.org/10.1186/s12859-020-3346-8
Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets
Computational and Structural Biotechnology Journal / Jan 01, 2022
Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029
Emily Owens
Professor, Department of Criminology, Law and Society
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Other Research Interests (41)
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Most Relevant Publications (1+)
69 total publications
Police oversight in Ireland: Who complains, who gains?
CrimRxiv / Nov 07, 2022
Moss, B. (2022). Police oversight in Ireland: Who complains, who gains? CrimRxiv. https://doi.org/10.21428/cb6ab371.d0b0b56e
Sumeet K. Tiwari
Bioinformatic researcher at Quadram Institute Bioscience
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Other Research Interests (20)
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Most Relevant Publications (1+)
16 total publications
Genome-wide association reveals host-specific genomic traits in Escherichia coli
BMC Biology / Apr 11, 2023
Tiwari, S. K., van der Putten, B. C. L., Fuchs, T. M., Vinh, T. N., Bootsma, M., Oldenkamp, R., La Ragione, R., Matamoros, S., Hoa, N. T., Berens, C., Leng, J., Álvarez, J., Ferrandis-Vila, M., Ritchie, J. M., Fruth, A., Schwarz, S., Domínguez, L., Ugarte-Ruiz, M., Bethe, A., … Schultsz, C. (2023). Genome-wide association reveals host-specific genomic traits in Escherichia coli. BMC Biology, 21(1). https://doi.org/10.1186/s12915-023-01562-w
Asst. Prof. Eng. Davide Verzotto, Ph.D.
Assistant Professor of Computer Science, Centre for Higher Defence Studies (CASD) - School of Advanced Studies, Italian Defence General Staff, Rome
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Other Research Interests (20)
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Most Relevant Publications (3+)
40 total publications
Alignment-free phylogeny of whole genomes using underlying subwords
Algorithms for Molecular Biology / Dec 01, 2012
Comin, M., & Verzotto, D. (2012). Alignment-free phylogeny of whole genomes using underlying subwords. Algorithms for Molecular Biology, 7(1). https://doi.org/10.1186/1748-7188-7-34
Classification of protein sequences by means of irredundant patterns
BMC Bioinformatics / Jan 01, 2010
Comin, M., & Verzotto, D. (2010). Classification of protein sequences by means of irredundant patterns. BMC Bioinformatics, 11(S1). https://doi.org/10.1186/1471-2105-11-s1-s16
Classification of protein sequences by means of irredundant patterns
BMC Bioinformatics / Jan 01, 2010
Comin, M., & Verzotto, D. (2010). Classification of protein sequences by means of irredundant patterns. BMC Bioinformatics, 11(S1). https://doi.org/10.1186/1471-2105-11-s1-s16
Jonathan Moore
Genome edit designer
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Other Research Interests (55)
Most Relevant Publications (2+)
72 total publications
MCMC-ODPR: Primer design optimization using Markov Chain Monte Carlo sampling
BMC Bioinformatics / Nov 05, 2012
Kitchen, J. L., Moore, J. D., Palmer, S. A., & Allaby, R. G. (2012). MCMC-ODPR: Primer design optimization using Markov Chain Monte Carlo sampling. BMC Bioinformatics, 13(1). https://doi.org/10.1186/1471-2105-13-287
CWRML: representing crop wild relative conservation and use data in XML
BMC Bioinformatics / Feb 25, 2008
Moore, J. D., Kell, S. P., Iriondo, J. M., Ford-Lloyd, B. V., & Maxted, N. (2008). CWRML: representing crop wild relative conservation and use data in XML. BMC Bioinformatics, 9(1). https://doi.org/10.1186/1471-2105-9-116
David Studholme
Senior Lecturer / Associate Professor at University of Exeter
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Other Research Interests (55)
Most Relevant Publications (3+)
190 total publications
Assessing the performance of the Oxford Nanopore Technologies MinION
Biomolecular Detection and Quantification / Mar 01, 2015
Laver, T., Harrison, J., O’Neill, P. A., Moore, K., Farbos, A., Paszkiewicz, K., & Studholme, D. J. (2015). Assessing the performance of the Oxford Nanopore Technologies MinION. Biomolecular Detection and Quantification, 3, 1–8. https://doi.org/10.1016/j.bdq.2015.02.001
Mechanism of Action of the Escherichia coli Phage Shock Protein PspA in Repression of the AAA Family Transcription Factor PspF
Journal of Molecular Biology / Jun 01, 2002
Elderkin, S., Jones, S., Schumacher, J., Studholme, D., & Buck, M. (2002). Mechanism of Action of the Escherichia coli Phage Shock Protein PspA in Repression of the AAA Family Transcription Factor PspF. Journal of Molecular Biology, 320(1), 23–37. https://doi.org/10.1016/s0022-2836(02)00404-7
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
BMC Bioinformatics / Feb 18, 2010
MacLean, D., Moulton, V., & Studholme, D. J. (2010). Finding sRNA generative locales from high-throughput sequencing data with NiBLS. BMC Bioinformatics, 11(1). https://doi.org/10.1186/1471-2105-11-93
Nitin Pandey
Assistant Professor of Physiology and Neuroscience, University of Southern California
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Other Research Interests (31)
Most Relevant Publications (11+)
27 total publications
(−)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme
International Journal of Biological Macromolecules / Mar 01, 2013
Ghosh, S., Pandey, N. K., & Dasgupta, S. (2013). (−)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme. International Journal of Biological Macromolecules, 54, 90–98. https://doi.org/10.1016/j.ijbiomac.2012.11.031
Fructose restrains fibrillogenesis in human serum albumin
International Journal of Biological Macromolecules / Oct 01, 2013
Pandey, N. K., Ghosh, S., & Dasgupta, S. (2013). Fructose restrains fibrillogenesis in human serum albumin. International Journal of Biological Macromolecules, 61, 424–432. https://doi.org/10.1016/j.ijbiomac.2013.08.006
Effect of surfactants on preformed fibrils of human serum albumin
International Journal of Biological Macromolecules / Aug 01, 2013
Pandey, N. K., Ghosh, S., & Dasgupta, S. (2013). Effect of surfactants on preformed fibrils of human serum albumin. International Journal of Biological Macromolecules, 59, 39–45. https://doi.org/10.1016/j.ijbiomac.2013.04.014
Effect of (−)-epigallocatechin gallate on the fibrillation of human serum albumin
International Journal of Biological Macromolecules / Sep 01, 2014
Bhattacharya, S., Pandey, N. K., Roy, A., & Dasgupta, S. (2014). Effect of (−)-epigallocatechin gallate on the fibrillation of human serum albumin. International Journal of Biological Macromolecules, 70, 312–319. https://doi.org/10.1016/j.ijbiomac.2014.07.003
Copper(II) directs formation of toxic amorphous aggregates resulting in inhibition of hen egg white lysozyme fibrillation under alkaline salt-mediated conditions
Journal of Biomolecular Structure and Dynamics / May 28, 2014
Ghosh, S., Pandey, N. K., Banerjee, P., Chaudhury, K., Nagy, N. V., & Dasgupta, S. (2014). Copper(II) directs formation of toxic amorphous aggregates resulting in inhibition of hen egg white lysozyme fibrillation under alkaline salt-mediated conditions. Journal of Biomolecular Structure and Dynamics, 33(5), 991–1007. https://doi.org/10.1080/07391102.2014.921864
Fibrillation of hen egg white lysozyme triggers reduction of copper(II)
International Journal of Biological Macromolecules / Jul 01, 2012
Ghosh, S., Pandey, N. K., Bhattacharya, S., Roy, A., & Dasgupta, S. (2012). Fibrillation of hen egg white lysozyme triggers reduction of copper(II). International Journal of Biological Macromolecules, 51(1–2), 1–6. https://doi.org/10.1016/j.ijbiomac.2012.04.024
Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms
Structure / Oct 01, 2019
Tao, M., Pandey, N. K., Barnes, R., Han, S., & Langen, R. (2019). Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms. Structure, 27(10), 1570-1580.e4. https://doi.org/10.1016/j.str.2019.08.003
Fibrillation of human serum albumin shows nonspecific coordination on stoichiometric increment of Copper(II)
Journal of Biomolecular Structure and Dynamics / Jul 22, 2013
Pandey, N. K., Ghosh, S., Nagy, N. V., & Dasgupta, S. (2013). Fibrillation of human serum albumin shows nonspecific coordination on stoichiometric increment of Copper(II). Journal of Biomolecular Structure and Dynamics, 32(9), 1366–1378. https://doi.org/10.1080/07391102.2013.819300
Evidence of two oxidation states of copper during aggregation of hen egg white lysozyme (HEWL)
International Journal of Biological Macromolecules / May 01, 2015
Ghosh, S., Pandey, N. K., Bhattacharya, S., Roy, A., Nagy, N. V., & Dasgupta, S. (2015). Evidence of two oxidation states of copper during aggregation of hen egg white lysozyme (HEWL). International Journal of Biological Macromolecules, 76, 1–9. https://doi.org/10.1016/j.ijbiomac.2015.02.014
Effect of Temperature and Solvent on Fibrillation of Human Serum Albumin
Protein & Peptide Letters / Jan 28, 2015
Pandey, N., Ghosh, S., Tripathy, D., & Dasgupta, S. (2015). Effect of Temperature and Solvent on Fibrillation of Human Serum Albumin. Protein & Peptide Letters, 22(2), 112–118. https://doi.org/10.2174/0929866521666140320104409
An insight into the ribonucleolytic and antiangiogenic activity of buffalo lactoferrin
Journal of Biomolecular Structure and Dynamics / Dec 10, 2013
Tripathy, D. R., Pandey, N. K., Dinda, A. K., Ghosh, S., Singha Roy, A., & Dasgupta, S. (2013). An insight into the ribonucleolytic and antiangiogenic activity of buffalo lactoferrin. Journal of Biomolecular Structure and Dynamics, 33(1), 184–195. https://doi.org/10.1080/07391102.2013.865564
Dr. Susanne Ressl
Biochemist & Structural Biologist | Project & Team Leader | Creative & Translational Thinker | Problem Solver | Mentor | Educator | Consultant | Innovator | Science Communicator & Writer | Relationship Builder | Collaborator
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Other Research Interests (26)
Most Relevant Publications (1+)
20 total publications
Structures of C1q-like Proteins Reveal Unique Features among the C1q/TNF Superfamily
Structure / Apr 01, 2015
Ressl, S., Vu, B. K., Vivona, S., Martinelli, D. C., Südhof, T. C., & Brunger, A. T. (2015). Structures of C1q-like Proteins Reveal Unique Features among the C1q/TNF Superfamily. Structure, 23(4), 688–699. https://doi.org/10.1016/j.str.2015.01.019
Matheus Ferraz
PhD in computational chemistry, bioinformatician with experience in industry
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Other Research Interests (31)
Most Relevant Publications (1+)
17 total publications
Identification of potential Staphylococcus aureus dihydrofolate reductase inhibitors using QSAR, molecular docking, dynamics simulations and free energy calculation
Journal of Biomolecular Structure and Dynamics / Mar 31, 2022
Matos, I. de A., Goes Pinto, A. C., Ferraz, M. V. F., Adan, W. C. S., Rodrigues, R. P., dos Santos, J. X., Kitagawa, R. R., Lins, R. D., Oliveira, T. B., & Costa Junior, N. B. da. (2022). Identification of potential Staphylococcus aureus dihydrofolate reductase inhibitors using QSAR, molecular docking, dynamics simulations and free energy calculation. Journal of Biomolecular Structure and Dynamics, 41(9), 3835–3846. https://doi.org/10.1080/07391102.2022.2057361
Example structural biology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on structural biology?
Structure-Based Drug Design
A pharmaceutical company can collaborate with a structural biologist to design new drugs by studying the structure of target molecules and identifying potential binding sites for drug molecules.
Protein Engineering for Industrial Applications
A biotechnology company can work with a structural biologist to engineer proteins with improved properties for industrial applications, such as enzyme engineering for biofuel production.
Understanding Protein-Protein Interactions
A biopharmaceutical company can partner with a structural biologist to study the interactions between proteins involved in disease pathways, aiding in the development of targeted therapies.
Structural Analysis of Viral Proteins
A vaccine development company can collaborate with a structural biologist to determine the three-dimensional structures of viral proteins, facilitating the design of effective vaccines.
Structural Biology in Agriculture
An agricultural company can work with a structural biologist to understand the structure and function of plant proteins, leading to the development of improved crop varieties with enhanced traits.