Work with thought leaders and academic experts in toxicology

Companies can greatly benefit from working with experts in the field of Toxicology. These researchers can provide valuable insights and guidance in various areas such as research and development, product safety assessment, regulatory compliance, risk assessment, and toxicological consulting. By collaborating with Toxicology experts, companies can enhance their understanding of potential hazards, improve product safety, ensure compliance with regulations, and make informed decisions based on scientific evidence. Whether it's pharmaceuticals, chemicals, cosmetics, or consumer products, partnering with Toxicology researchers can help companies mitigate risks, optimize product performance, and protect public health.

Experts on NotedSource with backgrounds in toxicology include Dushani L. Palliyaguru, Ph.D., Aimee Eggler, Sarah Arpin, Ph.D., Dr. Erin Westgate, Ph.D., Abiodun Adewuya, Amir Manbachi, Este Leidmaa, PhD, Barry Setlow, Gregg Stanwood, Gianfranco Santovito, Patrick G. Grant, Ph.D., and Bryan L Williams.

Aimee Eggler

Villanova, Pennsylvania, United States of America
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Interests
Toxicology
Other Research Interests (26)
Biochemistry
Biochemistry education
Cell culture
Oxidative stress
Natural products
And 21 more
About
Dr. Eggler has 20 years of experience in the field of redox biology, with a focus on the Nrf2 transcription factor, a master regulator of antioxidant, detoxification and anti-inflammatory genes. She is also an award-winning educator and the recipient of the Villanova University Junior Faculty Excellence in Teaching award. Her interests in education include innovation in teaching metabolism from a logic-based perspective.
Most Relevant Publications (6+)

25 total publications

Comparison of human Nrf2 antibodies: A tale of two proteins

Toxicology Letters / Oct 01, 2015

Kemmerer, Z. A., Ader, N. R., Mulroy, S. S., & Eggler, A. L. (2015). Comparison of human Nrf2 antibodies: A tale of two proteins. Toxicology Letters, 238(2), 83–89. https://doi.org/10.1016/j.toxlet.2015.07.004

Modification of Keap1 Cysteine Residues by Sulforaphane

Chemical Research in Toxicology / Mar 10, 2011

Hu, C., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2011). Modification of Keap1 Cysteine Residues by Sulforaphane. Chemical Research in Toxicology, 24(4), 515–521. https://doi.org/10.1021/tx100389r

Prospective Type 1 and Type 2 Disulfides of Keap1 Protein

Chemical Research in Toxicology / Aug 26, 2008

Holland, R., Hawkins, A. E., Eggler, A. L., Mesecar, A. D., Fabris, D., & Fishbein, J. C. (2008). Prospective Type 1 and Type 2 Disulfides of Keap1 Protein. Chemical Research in Toxicology, 21(10), 2051–2060. https://doi.org/10.1021/tx800226m

Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent

Chemical Research in Toxicology / Feb 01, 2008

Eggler, A. L., Luo, Y., van Breemen, R. B., & Mesecar, A. D. (2008). Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent. Chemical Research in Toxicology, 21(2), 556–556. https://doi.org/10.1021/tx800015c

Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent

Chemical Research in Toxicology / Oct 13, 2007

Eggler, A. L., Luo, Y., van Breemen, R. B., & Mesecar, A. D. (2007). Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent. Chemical Research in Toxicology, 20(12), 1878–1884. https://doi.org/10.1021/tx700217c

Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase

Chemical Research in Toxicology / Jul 12, 2005

Dietz, B. M., Kang, Y.-H., Liu, G., Eggler, A. L., Yao, P., Chadwick, L. R., Pauli, G. F., Farnsworth, N. R., Mesecar, A. D., van Breemen, R. B., & Bolton, J. L. (2005). Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase. Chemical Research in Toxicology, 18(8), 1296–1305. https://doi.org/10.1021/tx050058x

Sarah Arpin, Ph.D.

Spokane, Washington, United States of America
Associate Professor of Psychology at Gonzaga University with expertise in the social psychology of close relationships, loneliness, and health. Additional expertise in quantitative methods, including intensive longitudinal designs and dyadic data analysis.
Most Relevant Research Interests
Toxicology
Other Research Interests (12)
loneliness
social relationships and health
dyadic data analysis
Social Psychology
Geriatrics and Gerontology
And 7 more
About
Dr. Arpin's research focuses on the application of quantitative methods to the study of social psychological processes, including social interactions, social emotions, and health behavioral outcomes. She has conducted extensive research and published in the areas of loneliness and social determinants of health, using experimental and survey methodology. Dr. Arpin also has experience as a methodology and data analytic consultant on several large grant-funded projects, including DOD-funded intervention studies targeting well-being and social resilience among service-members.
Most Relevant Publications (2+)

15 total publications

Drinking to Cope in the COVID-19 Era: An Investigation Among College Students

Journal of Studies on Alcohol and Drugs / Mar 01, 2021

Mohr, C. D., Umemoto, S. K., Rounds, T. W., Bouleh, P., & Arpin, S. N. (2021). Drinking to Cope in the COVID-19 Era: An Investigation Among College Students. Journal of Studies on Alcohol and Drugs, 82(2), 178–187. https://doi.org/10.15288/jsad.2021.82.178

Abstracts-Symposia

Alcoholism: Clinical and Experimental Research / May 30, 2014

Abstracts-Symposia. (2014). Alcoholism: Clinical and Experimental Research, 38, 293A-359A. https://doi.org/10.1111/acer.12452

Dr. Erin Westgate, Ph.D.

Assistant Professor of Social Psychology, researching boredom, interest, and thinking (and why we're so bad at it)
Most Relevant Research Interests
Toxicology
Other Research Interests (22)
social psychology
social cognition
emotion
Multidisciplinary
General Psychology
And 17 more
About
**Dr. Erin Westgate** (she/her/hers) is an Assistant Professor of Psychology at the University of Florida, where she studies boredom, interest, and why some thoughts are more engaging than others. ​She received her PhD in social psychology from the University of Virginia in 2018, and her undergraduate degree from Reed College. Much of her research has been on the conditions under which people enjoy or do not enjoy their own thoughts. She has extended that work to the larger question of why people become bored, developing a new model of boredom that explains what boredom is, why we experience it, and what happens when we do.  As part of this, she is investigating our desire for a life full of interesting, perspective-changing experiences - or a “psychologically rich” life.
Most Relevant Publications (5+)

53 total publications

Alcohol Does Not Increase Slow Wave Sleep

Alcoholism: Clinical and Experimental Research / Feb 10, 2012

Pressman, M. R. (2012). Alcohol Does Not Increase Slow Wave Sleep. Alcoholism: Clinical and Experimental Research, 36(8), 1474–1474. https://doi.org/10.1111/j.1530-0277.2012.01746.x

“I Will Take a Shot for Every ‘Like’ I Get on This Status”: Posting Alcohol-Related Facebook Content Is Linked to Drinking Outcomes

Journal of Studies on Alcohol and Drugs / May 01, 2014

Westgate, E. C., Neighbors, C., Heppner, H., Jahn, S., & Lindgren, K. P. (2014). “I Will Take a Shot for Every ‘Like’ I Get on This Status”: Posting Alcohol-Related Facebook Content Is Linked to Drinking Outcomes. Journal of Studies on Alcohol and Drugs, 75(3), 390–398. https://doi.org/10.15288/jsad.2014.75.390

Self-Control and Implicit Drinking Identity as Predictors of Alcohol Consumption, Problems, and Cravings

Journal of Studies on Alcohol and Drugs / Mar 01, 2014

Lindgren, K. P., Neighbors, C., Westgate, E., & Salemink, E. (2014). Self-Control and Implicit Drinking Identity as Predictors of Alcohol Consumption, Problems, and Cravings. Journal of Studies on Alcohol and Drugs, 75(2), 290–298. https://doi.org/10.15288/jsad.2014.75.290

Implicit drinking identity: Drinker+me associations predict college student drinking consistently

Addictive Behaviors / May 01, 2013

Lindgren, K. P., Foster, D. W., Westgate, E. C., & Neighbors, C. (2013). Implicit drinking identity: Drinker+me associations predict college student drinking consistently. Addictive Behaviors, 38(5), 2163–2166. https://doi.org/10.1016/j.addbeh.2013.01.026

Pick your poison: Stimuli selection in alcohol-related implicit measures

Addictive Behaviors / Aug 01, 2012

Lindgren, K. P., Westgate, E. C., Kilmer, J. R., Kaysen, D., & Teachman, B. A. (2012). Pick your poison: Stimuli selection in alcohol-related implicit measures. Addictive Behaviors, 37(8), 990–993. https://doi.org/10.1016/j.addbeh.2012.03.024

Amir Manbachi

Co-director and Founder of the Johns Hopkins HEPIUS Innovation Lab
Most Relevant Research Interests
Toxicology
Other Research Interests (42)
Biomedical Engineering
Engineering Design
Medical Devices
Ultrasound
Neurosurgery
And 37 more
Most Relevant Publications (1+)

92 total publications

Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development

Applied In Vitro Toxicology / Jun 01, 2016

Ribas, J., Sadeghi, H., Manbachi, A., Leijten, J., Brinegar, K., Zhang, Y. S., Ferreira, L., & Khademhosseini, A. (2016). Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development. Applied In Vitro Toxicology, 2(2), 82–96. https://doi.org/10.1089/aivt.2016.0002

Este Leidmaa, PhD

Researcher in neuroscience studing cell adhesion molecules, endocannabinoid system and the BBB
Most Relevant Research Interests
Toxicology
Other Research Interests (30)
neuroscience
regulation of feeding behaviour
endocannabinoids
neurogenesis
astrocytes
And 25 more
Most Relevant Publications (1+)

19 total publications

Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system

Pharmacology Biochemistry and Behavior / Nov 01, 2020

Bregin, A., Kaare, M., Jagomäe, T., Karis, K., Singh, K., Laugus, K., Innos, J., Leidmaa, E., Heinla, I., Visnapuu, T., Oja, E.-M., Kõiv, K., Lilleväli, K., Harro, J., Philips, M.-A., & Vasar, E. (2020). Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system. Pharmacology Biochemistry and Behavior, 198, 173017. https://doi.org/10.1016/j.pbb.2020.173017

Gianfranco Santovito

Associate Professor of Physiology at the University of Padova
Most Relevant Research Interests
Toxicology
Other Research Interests (52)
Fisiologia degli organismi acquatici
Microbiology
Genetics
General Medicine
Molecular Biology
And 47 more
Most Relevant Publications (12+)

130 total publications

Antioxidant responses of the Mediterranean mussel, Mytilus galloprovincialis, to environmental variability of dissolved oxygen

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Mar 01, 2005

Santovito, G., Piccinni, E., Cassini, A., Irato, P., & Albergoni, V. (2005). Antioxidant responses of the Mediterranean mussel, Mytilus galloprovincialis, to environmental variability of dissolved oxygen. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 140(3–4), 321–329. https://doi.org/10.1016/j.cca.2005.02.015

Metal Accumulation and Binding Protein Induction in Mytilus galloprovincialis , Scapharca inaequivalvis , and Tapes philippinarum from the Lagoon of Venice

Archives of Environmental Contamination and Toxicology / May 01, 2003

Irato, P., Santovito, G., Cassini, A., Piccinni, E., & Albergoni, V. (2003). Metal Accumulation and Binding Protein Induction in Mytilus galloprovincialis , Scapharca inaequivalvis , and Tapes philippinarum from the Lagoon of Venice. Archives of Environmental Contamination and Toxicology, 44(4), 476–484. https://doi.org/10.1007/s00244-002-1262-8

MTT2, a copper-inducible metallothionein gene from Tetrahymena thermophila

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Mar 01, 2008

Boldrin, F., Santovito, G., Formigari, A., Bisharyan, Y., Cassidy-Hanley, D., Clark, T. G., & Piccinni, E. (2008). MTT2, a copper-inducible metallothionein gene from Tetrahymena thermophila. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 147(2), 232–240. https://doi.org/10.1016/j.cbpc.2007.10.002

Comparative study on metal homeostasis and detoxification in two Antarctic teleosts

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / May 01, 2012

Santovito, G., Piccinni, E., Boldrin, F., & Irato, P. (2012). Comparative study on metal homeostasis and detoxification in two Antarctic teleosts. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 155(4), 580–586. https://doi.org/10.1016/j.cbpc.2012.01.008

Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc

Archives of Toxicology / Sep 01, 2002

Medici, V., Santon, A., Sturniolo, G., D’Incà, R., Giannetto, S., Albergoni, V., & Irato, P. (2002). Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc. Archives of Toxicology, 76(9), 509–516. https://doi.org/10.1007/s00204-002-0377-z

Non-enzymatic antioxidant responses of Mytilus galloprovincialis: Insights into the physiological role against metal-induced oxidative stress

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Feb 01, 2021

Santovito, G., Trentin, E., Gobbi, I., Bisaccia, P., Tallandini, L., & Irato, P. (2021). Non-enzymatic antioxidant responses of Mytilus galloprovincialis: Insights into the physiological role against metal-induced oxidative stress. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 240, 108909. https://doi.org/10.1016/j.cbpc.2020.108909

Stress granules in Ciona robusta: First evidences of TIA-1-related nucleolysin and tristetraprolin gene expression under metal exposure

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / May 01, 2021

Laura, D., Anna, P., Nicola, F., Loriano, B., Rigers, B., & Gianfranco, S. (2021). Stress granules in Ciona robusta: First evidences of TIA-1-related nucleolysin and tristetraprolin gene expression under metal exposure. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 243, 108977. https://doi.org/10.1016/j.cbpc.2021.108977

Molecular characterization of novel mitochondrial peroxiredoxins from the Antarctic emerald rockcod and their gene expression in response to environmental warming

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Nov 01, 2019

Tolomeo, A. M., Carraro, A., Bakiu, R., Toppo, S., Garofalo, F., Pellegrino, D., Gerdol, M., Ferro, D., Place, S. P., & Santovito, G. (2019). Molecular characterization of novel mitochondrial peroxiredoxins from the Antarctic emerald rockcod and their gene expression in response to environmental warming. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 225, 108580. https://doi.org/10.1016/j.cbpc.2019.108580

Molecular characterization and metal induced gene expression of the novel glutathione peroxidase 7 from the chordate invertebrate Ciona robusta

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Feb 01, 2018

Ferro, D., Franchi, N., Bakiu, R., Ballarin, L., & Santovito, G. (2018). Molecular characterization and metal induced gene expression of the novel glutathione peroxidase 7 from the chordate invertebrate Ciona robusta. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 205, 1–7. https://doi.org/10.1016/j.cbpc.2017.12.002

Metal and metallothionein distribution in different tissues of the Mediterranean clam Venerupis philippinarum during copper treatment and detoxification

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Aug 01, 2015

Santovito, G., Boldrin, F., & Irato, P. (2015). Metal and metallothionein distribution in different tissues of the Mediterranean clam Venerupis philippinarum during copper treatment and detoxification. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 174–175, 46–53. https://doi.org/10.1016/j.cbpc.2015.06.008

Molecular and functional evolution of Tetrahymena metallothioneins: New insights into the gene family of Tetrahymena thermophila

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Jan 01, 2007

Santovito, G., Formigari, A., Boldrin, F., & Piccinni, E. (2007). Molecular and functional evolution of Tetrahymena metallothioneins: New insights into the gene family of Tetrahymena thermophila. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 144(4), 391–397. https://doi.org/10.1016/j.cbpc.2006.11.010

Cu,Zn superoxide dismutase from Trematomus bernacchii: Functional conservation and erratic molecular evolution in Antarctic teleosts

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Aug 01, 2006

Santovito, G., Cassini, A., & Piccinni, E. (2006). Cu,Zn superoxide dismutase from Trematomus bernacchii: Functional conservation and erratic molecular evolution in Antarctic teleosts. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 143(4), 444–454. https://doi.org/10.1016/j.cbpc.2006.04.007

Patrick G. Grant, Ph.D.

California
Multi Discipline Experience with Multiple Open Inovation Solutions
Most Relevant Research Interests
Toxicology
Other Research Interests (42)
Multidisciplinary
General Agricultural and Biological Sciences
General Chemistry
Mechanical Engineering
Mechanics of Materials
And 37 more
Most Relevant Publications (2+)

41 total publications

Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay

Natural Toxins / Jan 01, 1995

Phillips, T. D., Sarr, A. B., & Grant, P. G. (1995). Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay. Natural Toxins, 3(4), 204–213. https://doi.org/10.1002/nt.2620030407

Quantitative Particle-Induced X-ray Emission Imaging of Rat Olfactory Epithelium Applied to the Permeability of Rat Epithelium to Inhaled Aluminum

Chemical Research in Toxicology / Jun 04, 1999

Divine, K. K., Lewis, J. L., Grant, P. G., & Bench, G. (1999). Quantitative Particle-Induced X-ray Emission Imaging of Rat Olfactory Epithelium Applied to the Permeability of Rat Epithelium to Inhaled Aluminum. Chemical Research in Toxicology, 12(7), 575–581. https://doi.org/10.1021/tx9900268

Bryan L Williams

Medical College of Georgia
Most Relevant Research Interests
Toxicology
Other Research Interests (46)
Pediatrics
Epidemiology
Maternal and Child Health
Exposure Assessment
Health, Toxicology and Mutagenesis
And 41 more
Most Relevant Publications (5+)

62 total publications

Inter- and intra-ethnic variation in water intake, contact, and source estimates among Tucson residents: Implications for exposure analysis

Journal of Exposure Science & Environmental Epidemiology / Dec 01, 2001

WILLIAMS, B. L., FLOREZ, Y., & PETTYGROVE, S. (2001). Inter- and intra-ethnic variation in water intake, contact, and source estimates among Tucson residents: Implications for exposure analysis. Journal of Exposure Science & Environmental Epidemiology, 11(6), 510–521. https://doi.org/10.1038/sj.jea.7500192

Assessing the impact of the local environment on birth outcomes: a case for HLM

Journal of Exposure Science & Environmental Epidemiology / Dec 13, 2006

Williams, B. L., Pennock-Román, M., Suen, H. K., Magsumbol, M. S., & Ozdenerol, E. (2006). Assessing the impact of the local environment on birth outcomes: a case for HLM. Journal of Exposure Science & Environmental Epidemiology, 17(5), 445–457. https://doi.org/10.1038/sj.jes.7500537

Metals in Laysan Albatrosses from Midway Atoll

Archives of Environmental Contamination and Toxicology / Feb 01, 2000

Burger, J., & Gochfeld, M. (2000). Metals in Laysan Albatrosses from Midway Atoll. Archives of Environmental Contamination and Toxicology, 38(2), 254–259. https://doi.org/10.1007/s002449910033

Urinary Paranitrophenol, a Metabolite of Methyl Parathion, in Thai Farmer and Child Populations

Archives of Environmental Contamination and Toxicology / Apr 14, 2009

Panuwet, P., Prapamontol, T., Chantara, S., Thavornyuthikarn, P., Bravo, R., Restrepo, P., Walker, R. D., Williams, B. L., Needham, L. L., & Barr, D. B. (2009). Urinary Paranitrophenol, a Metabolite of Methyl Parathion, in Thai Farmer and Child Populations. Archives of Environmental Contamination and Toxicology, 57(3), 623–629. https://doi.org/10.1007/s00244-009-9315-x

Interpretation of biomonitoring data in clinical medicine and the exposure sciences

Toxicology and Applied Pharmacology / Nov 01, 2008

Williams, B. L., Barr, D. B., Wright, J. M., Buckley, B., & Magsumbol, M. S. (2008). Interpretation of biomonitoring data in clinical medicine and the exposure sciences. Toxicology and Applied Pharmacology, 233(1), 76–80. https://doi.org/10.1016/j.taap.2008.05.002

Example toxicology projects

How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on toxicology?

Pharmaceutical Drug Development

A pharmaceutical company can collaborate with a Toxicology expert to assess the safety and efficacy of new drug candidates. The researcher can conduct preclinical studies to evaluate the potential toxic effects of the drug, identify any adverse reactions, and provide recommendations for dose optimization and risk mitigation.

Chemical Risk Assessment

Companies involved in chemical manufacturing or distribution can benefit from working with a Toxicology researcher to assess the potential risks associated with their products. The expert can evaluate the toxicity profile of the chemicals, identify potential exposure routes, and recommend appropriate safety measures to protect workers and the environment.

Cosmetic Product Safety Evaluation

Cosmetic companies can collaborate with Toxicology experts to ensure the safety of their products. The researcher can assess the toxicological profile of cosmetic ingredients, evaluate potential skin sensitization or irritation, and provide guidance on formulation optimization to minimize potential risks to consumers.

Environmental Impact Assessment

Companies involved in industrial activities or infrastructure development can work with Toxicology researchers to assess the potential environmental impact of their projects. The expert can evaluate the toxicity of pollutants, assess their potential effects on ecosystems, and recommend mitigation strategies to minimize environmental harm.

Regulatory Compliance Support

Companies operating in regulated industries can collaborate with Toxicology experts to ensure compliance with relevant regulations. The researcher can provide toxicological data and risk assessments required for regulatory submissions, assist in interpreting and implementing regulatory guidelines, and help companies navigate complex compliance requirements.