Work with thought leaders and academic experts in toxicology
Companies can greatly benefit from working with experts in the field of Toxicology. These researchers can provide valuable insights and guidance in various areas such as research and development, product safety assessment, regulatory compliance, risk assessment, and toxicological consulting. By collaborating with Toxicology experts, companies can enhance their understanding of potential hazards, improve product safety, ensure compliance with regulations, and make informed decisions based on scientific evidence. Whether it's pharmaceuticals, chemicals, cosmetics, or consumer products, partnering with Toxicology researchers can help companies mitigate risks, optimize product performance, and protect public health.
Experts on NotedSource with backgrounds in toxicology include Dushani L. Palliyaguru, Ph.D., Aimee Eggler, Sarah Arpin, Ph.D., Dr. Erin Westgate, Ph.D., Abiodun Adewuya, Amir Manbachi, Este Leidmaa, PhD, Barry Setlow, Gregg Stanwood, Gianfranco Santovito, Patrick G. Grant, Ph.D., and Bryan L Williams.
Dushani L. Palliyaguru, Ph.D.
Toxicologist | Aging, Nutrition and Metabolism Research Scientist | Systems Biologist
Most Relevant Research Interests
Other Research Interests (20)
About
Most Relevant Publications (1+)
21 total publications
Global geographical overlap of aflatoxin and hepatitis C: controlling risk factors for liver cancer worldwide
Food Additives & Contaminants: Part A / Mar 01, 2013
Palliyaguru, D. L., & Wu, F. (2013). Global geographical overlap of aflatoxin and hepatitis C: controlling risk factors for liver cancer worldwide. Food Additives & Contaminants: Part A, 30(3), 534–540. https://doi.org/10.1080/19440049.2012.751630
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Interests
Other Research Interests (26)
About
Most Relevant Publications (6+)
25 total publications
Comparison of human Nrf2 antibodies: A tale of two proteins
Toxicology Letters / Oct 01, 2015
Kemmerer, Z. A., Ader, N. R., Mulroy, S. S., & Eggler, A. L. (2015). Comparison of human Nrf2 antibodies: A tale of two proteins. Toxicology Letters, 238(2), 83–89. https://doi.org/10.1016/j.toxlet.2015.07.004
Modification of Keap1 Cysteine Residues by Sulforaphane
Chemical Research in Toxicology / Mar 10, 2011
Hu, C., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2011). Modification of Keap1 Cysteine Residues by Sulforaphane. Chemical Research in Toxicology, 24(4), 515–521. https://doi.org/10.1021/tx100389r
Prospective Type 1 and Type 2 Disulfides of Keap1 Protein
Chemical Research in Toxicology / Aug 26, 2008
Holland, R., Hawkins, A. E., Eggler, A. L., Mesecar, A. D., Fabris, D., & Fishbein, J. C. (2008). Prospective Type 1 and Type 2 Disulfides of Keap1 Protein. Chemical Research in Toxicology, 21(10), 2051–2060. https://doi.org/10.1021/tx800226m
Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent
Chemical Research in Toxicology / Feb 01, 2008
Eggler, A. L., Luo, Y., van Breemen, R. B., & Mesecar, A. D. (2008). Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent. Chemical Research in Toxicology, 21(2), 556–556. https://doi.org/10.1021/tx800015c
Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent
Chemical Research in Toxicology / Oct 13, 2007
Eggler, A. L., Luo, Y., van Breemen, R. B., & Mesecar, A. D. (2007). Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent. Chemical Research in Toxicology, 20(12), 1878–1884. https://doi.org/10.1021/tx700217c
Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase
Chemical Research in Toxicology / Jul 12, 2005
Dietz, B. M., Kang, Y.-H., Liu, G., Eggler, A. L., Yao, P., Chadwick, L. R., Pauli, G. F., Farnsworth, N. R., Mesecar, A. D., van Breemen, R. B., & Bolton, J. L. (2005). Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase. Chemical Research in Toxicology, 18(8), 1296–1305. https://doi.org/10.1021/tx050058x
Sarah Arpin, Ph.D.
Associate Professor of Psychology at Gonzaga University with expertise in the social psychology of close relationships, loneliness, and health. Additional expertise in quantitative methods, including intensive longitudinal designs and dyadic data analysis.
Most Relevant Research Interests
Other Research Interests (12)
About
Most Relevant Publications (2+)
15 total publications
Drinking to Cope in the COVID-19 Era: An Investigation Among College Students
Journal of Studies on Alcohol and Drugs / Mar 01, 2021
Mohr, C. D., Umemoto, S. K., Rounds, T. W., Bouleh, P., & Arpin, S. N. (2021). Drinking to Cope in the COVID-19 Era: An Investigation Among College Students. Journal of Studies on Alcohol and Drugs, 82(2), 178–187. https://doi.org/10.15288/jsad.2021.82.178
Abstracts-Symposia
Alcoholism: Clinical and Experimental Research / May 30, 2014
Abstracts-Symposia. (2014). Alcoholism: Clinical and Experimental Research, 38, 293A-359A. https://doi.org/10.1111/acer.12452
Dr. Erin Westgate, Ph.D.
Assistant Professor of Social Psychology, researching boredom, interest, and thinking (and why we're so bad at it)
Most Relevant Research Interests
Other Research Interests (22)
About
Most Relevant Publications (5+)
53 total publications
Alcohol Does Not Increase Slow Wave Sleep
Alcoholism: Clinical and Experimental Research / Feb 10, 2012
Pressman, M. R. (2012). Alcohol Does Not Increase Slow Wave Sleep. Alcoholism: Clinical and Experimental Research, 36(8), 1474–1474. https://doi.org/10.1111/j.1530-0277.2012.01746.x
“I Will Take a Shot for Every ‘Like’ I Get on This Status”: Posting Alcohol-Related Facebook Content Is Linked to Drinking Outcomes
Journal of Studies on Alcohol and Drugs / May 01, 2014
Westgate, E. C., Neighbors, C., Heppner, H., Jahn, S., & Lindgren, K. P. (2014). “I Will Take a Shot for Every ‘Like’ I Get on This Status”: Posting Alcohol-Related Facebook Content Is Linked to Drinking Outcomes. Journal of Studies on Alcohol and Drugs, 75(3), 390–398. https://doi.org/10.15288/jsad.2014.75.390
Self-Control and Implicit Drinking Identity as Predictors of Alcohol Consumption, Problems, and Cravings
Journal of Studies on Alcohol and Drugs / Mar 01, 2014
Lindgren, K. P., Neighbors, C., Westgate, E., & Salemink, E. (2014). Self-Control and Implicit Drinking Identity as Predictors of Alcohol Consumption, Problems, and Cravings. Journal of Studies on Alcohol and Drugs, 75(2), 290–298. https://doi.org/10.15288/jsad.2014.75.290
Implicit drinking identity: Drinker+me associations predict college student drinking consistently
Addictive Behaviors / May 01, 2013
Lindgren, K. P., Foster, D. W., Westgate, E. C., & Neighbors, C. (2013). Implicit drinking identity: Drinker+me associations predict college student drinking consistently. Addictive Behaviors, 38(5), 2163–2166. https://doi.org/10.1016/j.addbeh.2013.01.026
Pick your poison: Stimuli selection in alcohol-related implicit measures
Addictive Behaviors / Aug 01, 2012
Lindgren, K. P., Westgate, E. C., Kilmer, J. R., Kaysen, D., & Teachman, B. A. (2012). Pick your poison: Stimuli selection in alcohol-related implicit measures. Addictive Behaviors, 37(8), 990–993. https://doi.org/10.1016/j.addbeh.2012.03.024
Abiodun Adewuya
Professor of Public Mental Health at Lagos State University College of Medicine
Most Relevant Research Interests
Other Research Interests (39)
About
Most Relevant Publications (1+)
113 total publications
Gender differences in the relationship between alcohol use and anxiety symptoms among Nigerian college students
Drug and Alcohol Dependence / Dec 01, 2006
Adewuya, A. O., Ola, B. A., & Aloba, O. O. (2006). Gender differences in the relationship between alcohol use and anxiety symptoms among Nigerian college students. Drug and Alcohol Dependence, 85(3), 255–257. https://doi.org/10.1016/j.drugalcdep.2006.05.016
Amir Manbachi
Co-director and Founder of the Johns Hopkins HEPIUS Innovation Lab
Most Relevant Research Interests
Other Research Interests (42)
Most Relevant Publications (1+)
92 total publications
Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development
Applied In Vitro Toxicology / Jun 01, 2016
Ribas, J., Sadeghi, H., Manbachi, A., Leijten, J., Brinegar, K., Zhang, Y. S., Ferreira, L., & Khademhosseini, A. (2016). Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development. Applied In Vitro Toxicology, 2(2), 82–96. https://doi.org/10.1089/aivt.2016.0002
Este Leidmaa, PhD
Researcher in neuroscience studing cell adhesion molecules, endocannabinoid system and the BBB
Most Relevant Research Interests
Other Research Interests (30)
Most Relevant Publications (1+)
19 total publications
Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system
Pharmacology Biochemistry and Behavior / Nov 01, 2020
Bregin, A., Kaare, M., Jagomäe, T., Karis, K., Singh, K., Laugus, K., Innos, J., Leidmaa, E., Heinla, I., Visnapuu, T., Oja, E.-M., Kõiv, K., Lilleväli, K., Harro, J., Philips, M.-A., & Vasar, E. (2020). Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system. Pharmacology Biochemistry and Behavior, 198, 173017. https://doi.org/10.1016/j.pbb.2020.173017
Barry Setlow
Dept. of Psychiatry; Center for Addiction Research and Education, University of Florida
Most Relevant Research Interests
Other Research Interests (36)
Most Relevant Publications (1+)
111 total publications
The importance of considering polysubstance use: lessons from cocaine research
Drug and Alcohol Dependence / Nov 01, 2018
Liu, Y., Williamson, V. G., Setlow, B., Cottler, L. B., & Knackstedt, L. A. (2018). The importance of considering polysubstance use: lessons from cocaine research. Drug and Alcohol Dependence, 192, 16–28. https://doi.org/10.1016/j.drugalcdep.2018.07.025
Gianfranco Santovito
Associate Professor of Physiology at the University of Padova
Most Relevant Research Interests
Other Research Interests (52)
Most Relevant Publications (12+)
130 total publications
Antioxidant responses of the Mediterranean mussel, Mytilus galloprovincialis, to environmental variability of dissolved oxygen
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Mar 01, 2005
Santovito, G., Piccinni, E., Cassini, A., Irato, P., & Albergoni, V. (2005). Antioxidant responses of the Mediterranean mussel, Mytilus galloprovincialis, to environmental variability of dissolved oxygen. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 140(3–4), 321–329. https://doi.org/10.1016/j.cca.2005.02.015
Metal Accumulation and Binding Protein Induction in Mytilus galloprovincialis , Scapharca inaequivalvis , and Tapes philippinarum from the Lagoon of Venice
Archives of Environmental Contamination and Toxicology / May 01, 2003
Irato, P., Santovito, G., Cassini, A., Piccinni, E., & Albergoni, V. (2003). Metal Accumulation and Binding Protein Induction in Mytilus galloprovincialis , Scapharca inaequivalvis , and Tapes philippinarum from the Lagoon of Venice. Archives of Environmental Contamination and Toxicology, 44(4), 476–484. https://doi.org/10.1007/s00244-002-1262-8
MTT2, a copper-inducible metallothionein gene from Tetrahymena thermophila
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Mar 01, 2008
Boldrin, F., Santovito, G., Formigari, A., Bisharyan, Y., Cassidy-Hanley, D., Clark, T. G., & Piccinni, E. (2008). MTT2, a copper-inducible metallothionein gene from Tetrahymena thermophila. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 147(2), 232–240. https://doi.org/10.1016/j.cbpc.2007.10.002
Comparative study on metal homeostasis and detoxification in two Antarctic teleosts
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / May 01, 2012
Santovito, G., Piccinni, E., Boldrin, F., & Irato, P. (2012). Comparative study on metal homeostasis and detoxification in two Antarctic teleosts. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 155(4), 580–586. https://doi.org/10.1016/j.cbpc.2012.01.008
Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc
Archives of Toxicology / Sep 01, 2002
Medici, V., Santon, A., Sturniolo, G., D’Incà, R., Giannetto, S., Albergoni, V., & Irato, P. (2002). Metallothionein and antioxidant enzymes in Long-Evans Cinnamon rats treated with zinc. Archives of Toxicology, 76(9), 509–516. https://doi.org/10.1007/s00204-002-0377-z
Non-enzymatic antioxidant responses of Mytilus galloprovincialis: Insights into the physiological role against metal-induced oxidative stress
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Feb 01, 2021
Santovito, G., Trentin, E., Gobbi, I., Bisaccia, P., Tallandini, L., & Irato, P. (2021). Non-enzymatic antioxidant responses of Mytilus galloprovincialis: Insights into the physiological role against metal-induced oxidative stress. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 240, 108909. https://doi.org/10.1016/j.cbpc.2020.108909
Stress granules in Ciona robusta: First evidences of TIA-1-related nucleolysin and tristetraprolin gene expression under metal exposure
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / May 01, 2021
Laura, D., Anna, P., Nicola, F., Loriano, B., Rigers, B., & Gianfranco, S. (2021). Stress granules in Ciona robusta: First evidences of TIA-1-related nucleolysin and tristetraprolin gene expression under metal exposure. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 243, 108977. https://doi.org/10.1016/j.cbpc.2021.108977
Molecular characterization of novel mitochondrial peroxiredoxins from the Antarctic emerald rockcod and their gene expression in response to environmental warming
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Nov 01, 2019
Tolomeo, A. M., Carraro, A., Bakiu, R., Toppo, S., Garofalo, F., Pellegrino, D., Gerdol, M., Ferro, D., Place, S. P., & Santovito, G. (2019). Molecular characterization of novel mitochondrial peroxiredoxins from the Antarctic emerald rockcod and their gene expression in response to environmental warming. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 225, 108580. https://doi.org/10.1016/j.cbpc.2019.108580
Molecular characterization and metal induced gene expression of the novel glutathione peroxidase 7 from the chordate invertebrate Ciona robusta
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Feb 01, 2018
Ferro, D., Franchi, N., Bakiu, R., Ballarin, L., & Santovito, G. (2018). Molecular characterization and metal induced gene expression of the novel glutathione peroxidase 7 from the chordate invertebrate Ciona robusta. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 205, 1–7. https://doi.org/10.1016/j.cbpc.2017.12.002
Metal and metallothionein distribution in different tissues of the Mediterranean clam Venerupis philippinarum during copper treatment and detoxification
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Aug 01, 2015
Santovito, G., Boldrin, F., & Irato, P. (2015). Metal and metallothionein distribution in different tissues of the Mediterranean clam Venerupis philippinarum during copper treatment and detoxification. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 174–175, 46–53. https://doi.org/10.1016/j.cbpc.2015.06.008
Molecular and functional evolution of Tetrahymena metallothioneins: New insights into the gene family of Tetrahymena thermophila
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Jan 01, 2007
Santovito, G., Formigari, A., Boldrin, F., & Piccinni, E. (2007). Molecular and functional evolution of Tetrahymena metallothioneins: New insights into the gene family of Tetrahymena thermophila. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 144(4), 391–397. https://doi.org/10.1016/j.cbpc.2006.11.010
Cu,Zn superoxide dismutase from Trematomus bernacchii: Functional conservation and erratic molecular evolution in Antarctic teleosts
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology / Aug 01, 2006
Santovito, G., Cassini, A., & Piccinni, E. (2006). Cu,Zn superoxide dismutase from Trematomus bernacchii: Functional conservation and erratic molecular evolution in Antarctic teleosts. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 143(4), 444–454. https://doi.org/10.1016/j.cbpc.2006.04.007
Patrick G. Grant, Ph.D.
Multi Discipline Experience with Multiple Open Inovation Solutions
Most Relevant Research Interests
Other Research Interests (42)
Most Relevant Publications (2+)
41 total publications
Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay
Natural Toxins / Jan 01, 1995
Phillips, T. D., Sarr, A. B., & Grant, P. G. (1995). Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay. Natural Toxins, 3(4), 204–213. https://doi.org/10.1002/nt.2620030407
Quantitative Particle-Induced X-ray Emission Imaging of Rat Olfactory Epithelium Applied to the Permeability of Rat Epithelium to Inhaled Aluminum
Chemical Research in Toxicology / Jun 04, 1999
Divine, K. K., Lewis, J. L., Grant, P. G., & Bench, G. (1999). Quantitative Particle-Induced X-ray Emission Imaging of Rat Olfactory Epithelium Applied to the Permeability of Rat Epithelium to Inhaled Aluminum. Chemical Research in Toxicology, 12(7), 575–581. https://doi.org/10.1021/tx9900268
Bryan L Williams
Medical College of Georgia
Most Relevant Research Interests
Other Research Interests (46)
Most Relevant Publications (5+)
62 total publications
Inter- and intra-ethnic variation in water intake, contact, and source estimates among Tucson residents: Implications for exposure analysis
Journal of Exposure Science & Environmental Epidemiology / Dec 01, 2001
WILLIAMS, B. L., FLOREZ, Y., & PETTYGROVE, S. (2001). Inter- and intra-ethnic variation in water intake, contact, and source estimates among Tucson residents: Implications for exposure analysis. Journal of Exposure Science & Environmental Epidemiology, 11(6), 510–521. https://doi.org/10.1038/sj.jea.7500192
Assessing the impact of the local environment on birth outcomes: a case for HLM
Journal of Exposure Science & Environmental Epidemiology / Dec 13, 2006
Williams, B. L., Pennock-Román, M., Suen, H. K., Magsumbol, M. S., & Ozdenerol, E. (2006). Assessing the impact of the local environment on birth outcomes: a case for HLM. Journal of Exposure Science & Environmental Epidemiology, 17(5), 445–457. https://doi.org/10.1038/sj.jes.7500537
Metals in Laysan Albatrosses from Midway Atoll
Archives of Environmental Contamination and Toxicology / Feb 01, 2000
Burger, J., & Gochfeld, M. (2000). Metals in Laysan Albatrosses from Midway Atoll. Archives of Environmental Contamination and Toxicology, 38(2), 254–259. https://doi.org/10.1007/s002449910033
Urinary Paranitrophenol, a Metabolite of Methyl Parathion, in Thai Farmer and Child Populations
Archives of Environmental Contamination and Toxicology / Apr 14, 2009
Panuwet, P., Prapamontol, T., Chantara, S., Thavornyuthikarn, P., Bravo, R., Restrepo, P., Walker, R. D., Williams, B. L., Needham, L. L., & Barr, D. B. (2009). Urinary Paranitrophenol, a Metabolite of Methyl Parathion, in Thai Farmer and Child Populations. Archives of Environmental Contamination and Toxicology, 57(3), 623–629. https://doi.org/10.1007/s00244-009-9315-x
Interpretation of biomonitoring data in clinical medicine and the exposure sciences
Toxicology and Applied Pharmacology / Nov 01, 2008
Williams, B. L., Barr, D. B., Wright, J. M., Buckley, B., & Magsumbol, M. S. (2008). Interpretation of biomonitoring data in clinical medicine and the exposure sciences. Toxicology and Applied Pharmacology, 233(1), 76–80. https://doi.org/10.1016/j.taap.2008.05.002
Example toxicology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on toxicology?
Pharmaceutical Drug Development
A pharmaceutical company can collaborate with a Toxicology expert to assess the safety and efficacy of new drug candidates. The researcher can conduct preclinical studies to evaluate the potential toxic effects of the drug, identify any adverse reactions, and provide recommendations for dose optimization and risk mitigation.
Chemical Risk Assessment
Companies involved in chemical manufacturing or distribution can benefit from working with a Toxicology researcher to assess the potential risks associated with their products. The expert can evaluate the toxicity profile of the chemicals, identify potential exposure routes, and recommend appropriate safety measures to protect workers and the environment.
Cosmetic Product Safety Evaluation
Cosmetic companies can collaborate with Toxicology experts to ensure the safety of their products. The researcher can assess the toxicological profile of cosmetic ingredients, evaluate potential skin sensitization or irritation, and provide guidance on formulation optimization to minimize potential risks to consumers.
Environmental Impact Assessment
Companies involved in industrial activities or infrastructure development can work with Toxicology researchers to assess the potential environmental impact of their projects. The expert can evaluate the toxicity of pollutants, assess their potential effects on ecosystems, and recommend mitigation strategies to minimize environmental harm.
Regulatory Compliance Support
Companies operating in regulated industries can collaborate with Toxicology experts to ensure compliance with relevant regulations. The researcher can provide toxicological data and risk assessments required for regulatory submissions, assist in interpreting and implementing regulatory guidelines, and help companies navigate complex compliance requirements.