Experts and Thought Leaders in Life Sciences

Food Processing and preservation

Microbiology

Biotechnology

Other Research Interests (10)

Food Chemistry and Nutrition

Food Product Development

Food Quality Control

Food Safety

And 5 more

About

Sarafa Adeyemi Akeem is an innovative, creative, highly motivated and result-oriented Food Researcher that is open to job opportunities as well as open to both national and international collaborations in the various areas of Food Chemistry/ biochemistry, Processing, Preservation, Process Engineering, Analysis, Quality Control, Safety, Product Development, Post Harvest Technology and Nutrition with the overall aim of contributing to the global food and nutrition security.

Most Relevant Publications (3+)

11 total publications

Physicochemical Properties of Processed Aerial Yam (Dioscorea bulbifera) and Sensory Properties of Paste (Amala) Prepared with Cassava Flour

Journal of Agricultural Sciences – Sri Lanka / May 01, 2017

EFFECTS OF ADDITION OF DIFFERENT SPICES ON THE QUALITY ATTRIBUTES OF TIGER-NUT MILK (KUNUN-AYA) DURING STORAGE

Journal of microbiology, biotechnology and food sciences / Aug 01, 2017

INFLUENCE OF PARTIAL SUBSTITUTION OF SUGAR WITH SERENDIPITY BERRY (DIOSCOREOPHYLLUM CUMMINSII) EXTRACT ON THE QUALITY ATTRIBUTES AND SHELF-LIFE OF WHEAT BREAD

Journal of microbiology, biotechnology and food sciences / Aug 01, 2019

Monday Ojo Kayode, R., Adunni Abiodun, O., Adeyemi Akeem, S., & Omodasola Oyeneye, H. (2019). INFLUENCE OF PARTIAL SUBSTITUTION OF SUGAR WITH SERENDIPITY BERRY (DIOSCOREOPHYLLUM CUMMINSII) EXTRACT ON THE QUALITY ATTRIBUTES AND SHELF-LIFE OF WHEAT BREAD. Journal of Microbiology, Biotechnology and Food Sciences, 9(1), 115–120. https://doi.org/10.15414/jmbfs.2019.9.1.115-120

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Tali Reiner Brodetzki

Philadelphia , Pennsylvania, United States of America

Assistant Professor at La Salle University

Most Relevant Research Interests

Animal Science and Zoology

Behavioral Neuroscience

Other Research Interests (8)

About

Tali Reiner Brodetzki is a highly accomplished scientist with a strong background in zoology. She received her Ph.D. in Zoology from Tel Aviv University in 2018, where she focused on the study of animal behavior and evolutionary ecology. During her graduate studies, she published several papers in top scientific journals and received numerous awards for her research. After completing her Ph.D., Tali went on to work as a Postdoctoral Fellow at both the University of Pennsylvania and Rutgers University. During this time, she continued to conduct research on animal behavior and evolution, and also gained valuable experience in teaching and mentoring students. In 2020, Tali joined the faculty at La Salle University as an Assistant Professor in the Department of Biology. She is currently conducting research on the effects of human activities on animal behavior and adaptation, and is also teaching undergraduate and graduate courses in zoology, bioinformatics, genomics, and evolutionary biology. Tali's research has been widely recognized and she has received numerous grants and awards, including the prestigious European Molecular Biology Organisation's postdoctoral award. She is also a member of several professional organizations, including the Society for Integrative and Comparative Biology and the Animal Behavior Society. In addition to her academic and research accomplishments, Tali is also passionate about science outreach and communication. She regularly presents her research at conferences and seminars, and also participates in science fairs and other community events. She is dedicated to inspiring the next generation of scientists and promoting the importance of studying and protecting our natural world. Overall, Tali Reiner Brodetzki is a highly skilled and dedicated scientist who is making significant contributions to the field of zoology. Her education and experience have prepared her to continue making important discoveries and advancements in the study of animal behavior and evolution.

Most Relevant Publications (3+)

9 total publications

An integrative approach to untangling species delimitation in the Cataglyphis bicolor desert ant complex in Israel

Molecular Phylogenetics and Evolution / Oct 01, 2017

Eyer, P. A., Seltzer, R., Reiner-Brodetzki, T., & Hefetz, A. (2017). An integrative approach to untangling species delimitation in the Cataglyphis bicolor desert ant complex in Israel. Molecular Phylogenetics and Evolution, 115, 128–139. https://doi.org/10.1016/j.ympev.2017.07.024

Lack of subspecies-recognition in breeding Barn Swallows (Hirundo rustica transitiva)

Behavioural Processes / Aug 01, 2021

Reiner Brodetzki, T., Lotem, A., Safran, R. J., & Hauber, M. E. (2021). Lack of subspecies-recognition in breeding Barn Swallows (Hirundo rustica transitiva). Behavioural Processes, 189, 104422. https://doi.org/10.1016/j.beproc.2021.104422

Worker demography and behavior in a supercolonial ant colony: The case of the desert ant Cataglyphis niger

Ethology / Oct 09, 2019

Reiner Brodetzki, T., Brodetzki, G., Feinerman, O., & Hefetz, A. (2019). Worker demography and behavior in a supercolonial ant colony: The case of the desert ant Cataglyphis niger. Ethology, 126(1), 59–67. Portico. https://doi.org/10.1111/eth.12960

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Martin Tsui

San Francisco, California, United States of America

University of California, San Francisco

Most Relevant Research Interests

Molecular Assembly and Interaction

Other Research Interests (14)

And 9 more

About

Martin Tsui is an accomplished scientist with a strong background in biochemistry. He received his Ph.D. in Molecular Biophysics from Florida State University in 2017, where he conducted research on the structure and function of CRISPR proteins. Prior to that, he obtained his B.S. in Chemistry from the University of California, San Diego in 2012. After completing his graduate studies, Martin founded his own company, Stealth, where he serves as a Founder & CEO. Under his leadership, the company has developed innovative solutions for the biotech industry and has gained recognition for its groundbreaking research. Before starting his company, Martin worked as a Senior Scientist at Amazon, where he applied his expertise in protein biochemistry and CRISPR to improve the company's product development processes and creating new products. He also gained valuable experience as a Postdoctoral Scholar at the University of California, San Francisco and Postdoctoral Fellow at the Van Andel Institute, where he studied cancer proteins, SARS-CoV-2, HIV proteins, and the role of proteins in neurodegenerative diseases, respectively. Martin is a highly driven and passionate individual who is dedicated to advancing the field of biotechnology. His impressive education and diverse experience have equipped him with the skills and knowledge to make significant contributions to the scientific community. He continues to pursue new opportunities to further his research and make a positive impact in the world of science.

Most Relevant Publications (4+)

17 total publications

Comparative host–pathogen protein–protein interaction analysis of recent coronavirus outbreaks and important host targets identification

Briefings in Bioinformatics / Sep 11, 2020

Khan, A. A., & Khan, Z. (2020). Comparative host–pathogen protein–protein interaction analysis of recent coronavirus outbreaks and important host targets identification. Briefings in Bioinformatics, 22(2), 1206–1214. https://doi.org/10.1093/bib/bbaa207

Structure Principles of CRISPR-Cas Surveillance and Effector Complexes

Annual Review of Biophysics / Jun 22, 2015

Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

Structure / Mar 01, 2023

Remesh, S. G., Merz, G. E., Brilot, A. F., Chio, U. S., Rizo, A. N., Pospiech, T. H., Lui, I., Laurie, M. T., Glasgow, J., Le, C. Q., Zhang, Y., Diwanji, D., Hernandez, E., Lopez, J., Mehmood, H., Pawar, K. I., Pourmal, S., Smith, A. M., Zhou, F., … Verba, K. A. (2023). Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31(3), 253-264.e6. https://doi.org/10.1016/j.str.2023.01.009

Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2

Nature Chemical Biology / Oct 20, 2020

Bracken, C. J., Lim, S. A., Solomon, P., Rettko, N. J., Nguyen, D. P., Zha, B. S., Schaefer, K., Byrnes, J. R., Zhou, J., Lui, I., Liu, J., Pance, K., Azumaya, C. M., Braxton, J. R., Brilot, A. F., Gupta, M., Li, F., Lopez, K. E., … Melo, A. (2020). Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2. Nature Chemical Biology, 17(1), 113–121. https://doi.org/10.1038/s41589-020-00679-1

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Xiaolei Wang

Raleigh, North Carolina, United States of America

R&D Scientist in biomedical imaging and surgical microscope development

Most Relevant Research Interests

Biotechnology

Optical imaging system development

Other Research Interests (17)

image analysis algorithm development

Atomic and Molecular Physics, and Optics

Mechanics of Materials

Mechanical Engineering

And 12 more

About

I am an R&D Optical Scientist and Expert specializing in Optical Imaging and Optical Microscope Development for biomedical and clinical applications. With a background in Physics and over 15 years of experience in optical science and imaging, I am passionate about pushing the boundaries of what light can achieve in the realm of medicine and healthcare. My journey in the world of optics has led me to become a leader in the research and development of next-generation optical imaging products that have a profound impact on surgical procedures and patient outcomes. My areas of expertise encompass optical physics, optical microscopy, optical metrology, photonics, and computational modeling and simulation. I've had the privilege of sharing my insights through multiple peer-reviewed publications in prestigious journals like ACS Nano, Optical Letter, and Advanced Materials. Additionally, I hold certifications in machine learning and deep learning for image analysis, allowing me to harness the power of cutting-edge technology in my work.

Most Relevant Publications (2+)

33 total publications

Computational multifocal microscopy

Biomedical Optics Express / Nov 28, 2018

He, K., Wang, Z., Huang, X., Wang, X., Yoo, S., Ruiz, P., Gdor, I., Selewa, A., Ferrier, N. J., Scherer, N., Hereld, M., Katsaggelos, A. K., & Cossairt, O. (2018). Computational multifocal microscopy. Biomedical Optics Express, 9(12), 6477. https://doi.org/10.1364/boe.9.006477

DeepProjection: specific and robust projection of curved 2D tissue sheets from 3D microscopy using deep learning

Development / Nov 01, 2022

Haertter, D., Wang, X., Fogerson, S. M., Ramkumar, N., Crawford, J. M., Poss, K. D., Di Talia, S., Kiehart, D. P., & Schmidt, C. F. (2022). DeepProjection: specific and robust projection of curved 2D tissue sheets from 3D microscopy using deep learning. Development, 149(21). https://doi.org/10.1242/dev.200621

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Regan Hamel

Cambridge

Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation

Most Relevant Research Interests

Immunology and Allergy

Regan Hamel has an MPhil and PhD in Clinical Neurosciences from University of Cambridge. She also has a Bachelor of Science in Neurosciences from McGill University. Her PhD with Stefano Pluchino and John Marioni focused on single cell transcriptomics in the context of neuroinflammation. Since 2021 she has worked as a Bioinformatics scientist at Mogrify Ltd, applying a multitude of computational biology techniques (including single cell omics, bulk RNAseq, and predictive modelling) in the context of cell reprogramming

Other Research Interests (7)

About

Most Relevant Publications (6+)

12 total publications

Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology

Frontiers in Cellular Neuroscience / Nov 05, 2020

Willis, C. M., Nicaise, A. M., Hamel, R., Pappa, V., Peruzzotti-Jametti, L., & Pluchino, S. (2020). Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology. Frontiers in Cellular Neuroscience, 14. https://doi.org/10.3389/fncel.2020.590960

Stem Cell Therapies for Progressive Multiple Sclerosis

Frontiers in Cell and Developmental Biology / Jul 09, 2021

Smith, J. A., Nicaise, A. M., Ionescu, R.-B., Hamel, R., Peruzzotti-Jametti, L., & Pluchino, S. (2021). Stem Cell Therapies for Progressive Multiple Sclerosis. Frontiers in Cell and Developmental Biology, 9. https://doi.org/10.3389/fcell.2021.696434

Metabolic Control of Smoldering Neuroinflammation

Frontiers in Immunology / Jun 23, 2021

Peruzzotti-Jametti, L., Willis, C. M., Hamel, R., Krzak, G., & Pluchino, S. (2021). Metabolic Control of Smoldering Neuroinflammation. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.705920

Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice

Molecular Therapy / Dec 01, 2020

Braga, A., Bandiera, S., Verheyen, J., Hamel, R., Rutigliani, C., Edenhofer, F., Smith, J. A., & Pluchino, S. (2020). Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Molecular Therapy, 28(12), 2677–2690. https://doi.org/10.1016/j.ymthe.2020.08.001

Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury

Frontiers in Immunology / Aug 24, 2022

Yao, X.-Q., Chen, J.-Y., Yu, Z.-H., Huang, Z.-C., Hamel, R., Zeng, Y.-Q., Huang, Z.-P., Tu, K.-W., Liu, J.-H., Lu, Y.-M., Zhou, Z.-T., Pluchino, S., Zhu, Q.-A., & Chen, J.-T. (2022). Bioinformatics analysis identified apolipoprotein E as a hub gene regulating neuroinflammation in macrophages and microglia following spinal cord injury. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.964138

Single cell biology—a Keystone Symposia report

Annals of the New York Academy of Sciences / Oct 03, 2021

Cable, J., Elowitz, M. B., Domingos, A. I., Habib, N., Itzkovitz, S., Hamidzada, H., Balzer, M. S., Yanai, I., Liberali, P., Whited, J., Streets, A., Cai, L., Stergachis, A. B., Hong, C. K. Y., Keren, L., Guilliams, M., Alon, U., Shalek, A. K., Hamel, R., … Romeike, M. (2021). Single cell biology—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1506(1), 74–97. Portico. https://doi.org/10.1111/nyas.14692

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Burcu Vitrinel, Ph.D.

San Francisco

Cross-functional life sciences strategy professional with a Ph.D. in genetics

Most Relevant Research Interests

Computer Science Applications

Other Research Interests (11)

Biochemistry

About

Cross-functional life sciences **strategy** professional with a doctoral degree in **genetics**; worked on 16+ projects in collaboration with 7+ big pharma clients as the lead consultant in a **client-facing** role. Exceptional understanding of current life sciences **market trends**. Scientist with 10+ years of wet-lab with hands-on **CRISPR-Cas9 gene** **editing and tandem mass-spectrometry** experience with 3 first-author papers. Experienced primary market researcher for pharmaceutical companies. Award-winning science communicator for a wide range of audiences tailored to different internal and external stakeholders.

Most Relevant Publications (5+)

10 total publications

Exploiting Interdata Relationships in Next-generation Proteomics Analysis

Molecular & Cellular Proteomics / Aug 01, 2019

Vitrinel, B., Koh, H. W. L., Mujgan Kar, F., Maity, S., Rendleman, J., Choi, H., & Vogel, C. (2019). Exploiting Interdata Relationships in Next-generation Proteomics Analysis. Molecular & Cellular Proteomics, 18(8), S5–S14. https://doi.org/10.1074/mcp.mr118.001246

Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity

Cell Systems / Dec 01, 2020

Shim, W. J., Sinniah, E., Xu, J., Vitrinel, B., Alexanian, M., Andreoletti, G., Shen, S., Sun, Y., Balderson, B., Boix, C., Peng, G., Jing, N., Wang, Y., Kellis, M., Tam, P. P. L., Smith, A., Piper, M., Christiaen, L., Nguyen, Q., … Palpant, N. J. (2020). Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity. Cell Systems, 11(6), 625-639.e13. https://doi.org/10.1016/j.cels.2020.11.001

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Aging Cell / Aug 09, 2019

Müthel, S., Uyar, B., He, M., Krause, A., Vitrinel, B., Bulut, S., Vasiljevic, D., Marchal, I., Kempa, S., Akalin, A., & Tursun, B. (2019). The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Aging Cell, 18(6). Portico. https://doi.org/10.1111/acel.13012

Ring Finger 149-Related Is an FGF/MAPK-Independent Regulator of Pharyngeal Muscle Fate Specification

International Journal of Molecular Sciences / May 16, 2023

Vitrinel, B., Vogel, C., & Christiaen, L. (2023). Ring Finger 149-Related Is an FGF/MAPK-Independent Regulator of Pharyngeal Muscle Fate Specification. International Journal of Molecular Sciences, 24(10), 8865. https://doi.org/10.3390/ijms24108865

Proteomic Signatures of the Serological Response to Influenza Vaccination in a Large Human Cohort Study

Viruses / Nov 09, 2022

Wu, S., Pushalkar, S., Maity, S., Pressler, M., Rendleman, J., Vitrinel, B., Carlock, M., Ross, T., Choi, H., & Vogel, C. (2022). Proteomic Signatures of the Serological Response to Influenza Vaccination in a Large Human Cohort Study. Viruses, 14(11), 2479. https://doi.org/10.3390/v14112479

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Dr. Everson A Nunes, Ph.D.

Hamilton, Ontario, Canada

Post-Doctoral Fellow at McMaster University | former Associate Professor - Physiological Sciences

Most Relevant Research Interests

Endocrinology, Diabetes and Metabolism

Orthopedics and Sports Medicine

Behavioral Neuroscience

Pathology and Forensic Medicine

Dr. Everson A Nunes is a highly accomplished researcher and educator in the field of physiological sciences. He received his Ph.D. in Cellular and Molecular Biology with a focus on Physiological Sciences from Universidade Federal do Paraná in 2009, after completing a BSc in Human Nutrition and an MSc in Physiological Sciences. He also holds a specialization in Exercise Physiology and a BSc in Biological Sciences from Universidade Federal do Paraná. Dr. Nunes has a strong background in research, having completed two post-doctoral fellowships at McMaster University and Universidade Federal do Paraná. He has also held positions as an associate professor and assistant professor at Universidade Federal de Santa Catarina. He has published numerous articles in peer-reviewed journals, and his research focuses on the effects of exercise and nutrition on physiological processes in the human body. In addition to his research, Dr. Nunes is also a dedicated educator. He has taught at various universities in Brazil, including Universidade Federal de Santa Catarina, Universidade Gama Filho, Faculdades Integradas Espírita, Pontificia Universidade Católica do Paraná, and Faculdade do Litoral Sul. He is known for his dynamic teaching style and his ability to engage students in complex physiological concepts. Dr. Nunes is a member of several professional organizations, including the American Society for Nutrition, the Canadian Society of Exercise Physiology, the Canadian Nutrition Society and the Brazilian Society of Physiology. He is also a regular speaker at national and international conferences, sharing his expertise and research findings with colleagues and students. Overall, Dr. Nunes is a highly qualified and experienced professional in physiological sciences, metabolism, cancer and nutrition. His dedication to research and education makes him a valuable asset to any institution.

Other Research Interests (29)

About

Most Relevant Publications (52+)

97 total publications

The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease

Frontiers in Nutrition / Sep 06, 2019

McGlory, C., Calder, P. C., & Nunes, E. A. (2019). The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health, Disuse, and Disease. Frontiers in Nutrition, 6. https://doi.org/10.3389/fnut.2019.00144

Systematic review and meta‐analysis of protein intake to support muscle mass and function in healthy adults

Journal of Cachexia, Sarcopenia and Muscle / Feb 20, 2022

Nunes, E. A., Colenso‐Semple, L., McKellar, S. R., Yau, T., Ali, M. U., Fitzpatrick‐Lewis, D., Sherifali, D., Gaudichon, C., Tomé, D., Atherton, P. J., Robles, M. C., Naranjo‐Modad, S., Braun, M., Landi, F., & Phillips, S. M. (2022). Systematic review and meta‐analysis of protein intake to support muscle mass and function in healthy adults. Journal of Cachexia, Sarcopenia and Muscle, 13(2), 795–810. Portico. https://doi.org/10.1002/jcsm.12922

Fish Oil Decreases C‐Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients

Lipids / Jul 26, 2013

Mocellin, M. C., Pastore e Silva, J. de A., Camargo, C. de Q., Fabre, M. E. de S., Gevaerd, S., Naliwaiko, K., Moreno, Y. M. F., Nunes, E. A., & Trindade, E. B. S. de M. (2013). Fish Oil Decreases C‐Reactive Protein/Albumin Ratio Improving Nutritional Prognosis and Plasma Fatty Acid Profile in Colorectal Cancer Patients. Lipids, 48(9), 879–888. Portico. https://doi.org/10.1007/s11745-013-3816-0

Anaerobic exercise reduces tumor growth, cancer cachexia and increases macrophage and lymphocyte response in Walker 256 tumor-bearing rats

European Journal of Applied Physiology / Aug 08, 2008

de Lima, C., Alves, L. E., Iagher, F., Machado, A. F., Bonatto, S. J., Kuczera, D., de Souza, C. F., Pequito, D. C., Muritiba, A. L., Nunes, E. A., & Fernandes, L. C. (2008). Anaerobic exercise reduces tumor growth, cancer cachexia and increases macrophage and lymphocyte response in Walker 256 tumor-bearing rats. European Journal of Applied Physiology, 104(6), 957–964. https://doi.org/10.1007/s00421-008-0849-9

Fish Oil Supplementation Improves Neutrophil Function During Cancer Chemotherapy

Lipids / Dec 11, 2011

Bonatto, S. J. R., Oliveira, H. H. P., Nunes, E. A., Pequito, D., Iagher, F., Coelho, I., Naliwaiko, K., Kryczyk, M., Brito, G. A. P., Repka, J., Sabóia, L. V., Fukujima, G., Calder, P. C., & Fernandes, L. C. (2011). Fish Oil Supplementation Improves Neutrophil Function During Cancer Chemotherapy. Lipids, 47(4), 383–389. Portico. https://doi.org/10.1007/s11745-011-3643-0

β-Hydroxy-β-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-κB expression

Nutrition Research / Jul 01, 2008

Nunes, E. A., Kuczera, D., Brito, G. A. P., Bonatto, S. J. R., Yamazaki, R. K., Tanhoffer, R. A., Mund, R. C., Kryczyk, M., & Fernandes, L. C. (2008). β-Hydroxy-β-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-κB expression. Nutrition Research, 28(7), 487–493. https://doi.org/10.1016/j.nutres.2008.04.006

Effects of Prebiotic and Synbiotic Supplementation on Inflammatory Markers and Anthropometric Indices After Roux-en-Y Gastric Bypass

Journal of Clinical Gastroenterology / Mar 01, 2016

Fernandes, R., Beserra, B. T. S., Mocellin, M. C., Kuntz, M. G. F., da Rosa, J. S., de Miranda, R. C. D., Schreiber, C. S. O., Fröde, T. S., Nunes, E. A., & Trindade, E. B. S. M. (2016). Effects of Prebiotic and Synbiotic Supplementation on Inflammatory Markers and Anthropometric Indices After Roux-en-Y Gastric Bypass: A Randomized, Triple-blind, Placebo-controlled Pilot Study. Journal of Clinical Gastroenterology, 50(3), 208–217. https://doi.org/10.1097/mcg.0000000000000328

Low fish oil intake improves insulin sensitivity, lipid profile and muscle metabolism on insulin resistant MSG-obese rats

Lipids in Health and Disease / Jan 01, 2011

Yamazaki, R. K., Brito, G. A., Coelho, I., Pequitto, D. C., Yamaguchi, A. A., Borghetti, G., Schiessel, D., Kryczyk, M., Machado, J., Rocha, R. E., Aikawa, J., Iagher, F., Naliwaiko, K., Tanhoffer, R. A., Nunes, E. A., & Fernandes, L. (2011). Low fish oil intake improves insulin sensitivity, lipid profile and muscle metabolism on insulin resistant MSG-obese rats. Lipids in Health and Disease, 10(1), 66. https://doi.org/10.1186/1476-511x-10-66

Equivalent Hypertrophy and Strength Gains in β-Hydroxy-β-Methylbutyrate- or Leucine-supplemented Men

Medicine & Science in Sports & Exercise / Jan 01, 2019

JAKUBOWSKI, J. S., WONG, E. P. T., NUNES, E. A., NOGUCHI, K. S., VANDEWEERD, J. K., MURPHY, K. T., MORTON, R. W., MCGLORY, C., & PHILLIPS, S. M. (2019). Equivalent Hypertrophy and Strength Gains in β-Hydroxy-β-Methylbutyrate- or Leucine-supplemented Men. Medicine & Science in Sports & Exercise, 51(1), 65–74. https://doi.org/10.1249/mss.0000000000001752

An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy

Medicine & Science in Sports & Exercise / Apr 06, 2022

LIM, C., NUNES, E. A., CURRIER, B. S., MCLEOD, J. C., THOMAS, A. C. Q., & PHILLIPS, S. M. (2022). An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy. Medicine & Science in Sports & Exercise, 54(9), 1546–1559. https://doi.org/10.1249/mss.0000000000002929

In vitro ketone‐supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle

The Journal of Physiology / Aug 19, 2020

Petrick, H. L., Brunetta, H. S., Pignanelli, C., Nunes, E. A., van Loon, L. J. C., Burr, J. F., & Holloway, G. P. (2020). In vitro ketone‐supported mitochondrial respiration is minimal when other substrates are readily available in cardiac and skeletal muscle. The Journal of Physiology, 598(21), 4869–4885. Portico. https://doi.org/10.1113/jp280032

Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats

Lipids in Health and Disease / Oct 16, 2013

Iagher, F., de Brito Belo, S. R., Souza, W. M., Nunes, J. R., Naliwaiko, K., Sassaki, G. L., Bonatto, S. J. R., de Oliveira, H. H. P., Brito, G. A. P., de Lima, C., Kryczyk, M., de Souza, C. F., Steffani, J. A., Nunes, E. A., & Fernandes, L. C. (2013). Antitumor and anti-cachectic effects of shark liver oil and fish oil: comparison between independent or associative chronic supplementation in Walker 256 tumor-bearing rats. Lipids in Health and Disease, 12(1). https://doi.org/10.1186/1476-511x-12-146

Interval training attenuates the metabolic disturbances in type 1 diabetes rat model

Arquivos Brasileiros de Endocrinologia & Metabologia / Nov 01, 2013

Rocha, R. E. R., Coelho, I., Pequito, D. C. T., Yamagushi, A., Borghetti, G., Yamazaki, R. K., Brito, G. A. P. de, Machado, J., Kryczyk, M., Nunes, E. A., Venera, G., & Fernandes, L. C. (2013). Interval training attenuates the metabolic disturbances in type 1 diabetes rat model. Arquivos Brasileiros de Endocrinologia & Metabologia, 57(8), 594–602. https://doi.org/10.1590/s0004-27302013000800003

Decrement in resting and insulin‐stimulated soleus muscle mitochondrial respiration is an early event in diet‐induced obesity in mice

Experimental Physiology / Jan 24, 2019

Brunetta, H. S., de Paula, G. C., de Oliveira, J., Martins, E. L., dos Santos, G. J., Galina, A., Rafacho, A., de Bem, A. F., & Nunes, E. A. (2019). Decrement in resting and insulin‐stimulated soleus muscle mitochondrial respiration is an early event in diet‐induced obesity in mice. Experimental Physiology, 104(3), 306–321. Portico. https://doi.org/10.1113/ep087317

Nitrate attenuates high fat diet‐induced glucose intolerance in association with reduced epididymal adipose tissue inflammation and mitochondrial reactive oxygen species emission

The Journal of Physiology / Jun 16, 2020

Brunetta, H. S., Politis‐Barber, V., Petrick, H. L., Dennis, K. M. J. H., Kirsh, A. J., Barbeau, P., Nunes, E. A., & Holloway, G. P. (2020). Nitrate attenuates high fat diet‐induced glucose intolerance in association with reduced epididymal adipose tissue inflammation and mitochondrial reactive oxygen species emission. The Journal of Physiology, 598(16), 3357–3371. Portico. https://doi.org/10.1113/jp279455

Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats

Canadian Journal of Physiology and Pharmacology / Oct 01, 2014

dos Santos, C., Ferreira, F. B. D., Gonçalves-Neto, L. M., Taboga, S. R., Boschero, A. C., & Rafacho, A. (2014). Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats. Canadian Journal of Physiology and Pharmacology, 92(10), 867–878. https://doi.org/10.1139/cjpp-2014-0259

Insulin rapidly increases skeletal muscle mitochondrial ADP sensitivity in the absence of a high lipid environment

Biochemical Journal / Jul 09, 2021

Brunetta, H. S., Petrick, H. L., Vachon, B., Nunes, E. A., & Holloway, G. P. (2021). Insulin rapidly increases skeletal muscle mitochondrial ADP sensitivity in the absence of a high lipid environment. Biochemical Journal, 478(13), 2539–2553. https://doi.org/10.1042/bcj20210264

An umbrella review of systematic reviews of β‐hydroxy‐β‐methyl butyrate supplementation in ageing and clinical practice

Journal of Cachexia, Sarcopenia and Muscle / Jul 12, 2022

Phillips, S. M., Lau, K. J., D’Souza, A. C., & Nunes, E. A. (2022). An umbrella review of systematic reviews of β‐hydroxy‐β‐methyl butyrate supplementation in ageing and clinical practice. Journal of Cachexia, Sarcopenia and Muscle, 13(5), 2265–2275. Portico. https://doi.org/10.1002/jcsm.13030

Heart rate reactivity to acute mental stress is associated with adiposity, carotid distensibility, sleep efficiency, and autonomic modulation in young men

Physiology & Behavior / Oct 01, 2022

Formolo, N. P. S., Filipini, R. E., Macedo, E. F. O., Corrêa, C. R., Nunes, E. A., Lima, L. R. A., & Speretta, G. F. (2022). Heart rate reactivity to acute mental stress is associated with adiposity, carotid distensibility, sleep efficiency, and autonomic modulation in young men. Physiology & Behavior, 254, 113908. https://doi.org/10.1016/j.physbeh.2022.113908

Increased protein intake derived from leucine-enriched protein enhances the integrated myofibrillar protein synthetic response to short-term resistance training in untrained men and women: a 4-day randomized controlled trial

Applied Physiology, Nutrition, and Metabolism / Nov 01, 2022

Lim, C., Traylor, D. A., McGlory, C., Joanisse, S., McKendry, J., Grewal, T., Mcleod, J. C., Prior, T., Nunes, E. A., Lees, M., & Phillips, S. M. (2022). Increased protein intake derived from leucine-enriched protein enhances the integrated myofibrillar protein synthetic response to short-term resistance training in untrained men and women: a 4-day randomized controlled trial. Applied Physiology, Nutrition, and Metabolism, 47(11), 1104–1114. https://doi.org/10.1139/apnm-2022-0164

Mixed-meal test reveals a worsen phenotypic flexibility correlated to central adiposity in clinically healthy young males

Clinical Nutrition ESPEN / Dec 01, 2020

Corrêa, C. R., Filipini, R. E., Mazera, M. S., Rafacho, A., & Nunes, E. A. (2020). Mixed-meal test reveals a worsen phenotypic flexibility correlated to central adiposity in clinically healthy young males. Clinical Nutrition ESPEN, 40, 622. https://doi.org/10.1016/j.clnesp.2020.09.650

Associação da atividade física, consumo de álcool e índice de massa corporal com a qualidade de vida de adolescentes

Revista Brasileira de Cineantropometria e Desempenho Humano / Jul 18, 2008

Gordia, A. P. (2008). Associação da atividade física, consumo de álcool e índice de massa corporal com a qualidade de vida de adolescentes. Revista Brasileira de Cineantropometria e Desempenho Humano, 10(3), 313. https://doi.org/10.5007/1980-0037.2008v10n3p313

β-hydroxy-β-methylbutyrate (HMB) Does Not Improve Resistance Exercise-Induced Changes In Body Composition: A Systematic-review And Meta-analysis

Medicine & Science in Sports & Exercise / Jul 01, 2020

Nunes, E. A., Jakubowski, J., Teixeira, F. J., Vescio, V., Morton, R. W., & Phillips, S. M. (2020). β-hydroxy-β-methylbutyrate (HMB) Does Not Improve Resistance Exercise-Induced Changes In Body Composition: A Systematic-review And Meta-analysis: 1698 Board #292 May 28 9:30 AM - 11:00 AM. Medicine & Science in Sports & Exercise, 52(7S), 456–457. https://doi.org/10.1249/01.mss.0000678888.31639.48

1739-P: Insulin Rapidly Increases Skeletal Muscle Mitochondrial ADP Sensitivity, Mitigating HFD-Induced Mitochondrial Dysfunction

Diabetes / Jun 01, 2020

BRUNETTA, H., PETRICK, H. L., NUNES, E. A., & HOLLOWAY, G. (2020). 1739-P: Insulin Rapidly Increases Skeletal Muscle Mitochondrial ADP Sensitivity, Mitigating HFD-Induced Mitochondrial Dysfunction. Diabetes, 69(Supplement_1). https://doi.org/10.2337/db20-1739-p

Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies

American Journal of Physiology-Cell Physiology / Jun 01, 2022

Nunes, E. A., Stokes, T., McKendry, J., Currier, B. S., & Phillips, S. M. (2022). Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies. American Journal of Physiology-Cell Physiology, 322(6), C1068–C1084. https://doi.org/10.1152/ajpcell.00425.2021

Dietary acid load is positively associated with insulin resistance: a population-based study

Clinical Nutrition ESPEN / Jun 01, 2022

Smeha, L., Fassula, A. S., Franco Moreno, Y. M., Gonzalez-Chica, D. A., & Nunes, E. A. (2022). Dietary acid load is positively associated with insulin resistance: a population-based study. Clinical Nutrition ESPEN, 49, 341–347. https://doi.org/10.1016/j.clnesp.2022.03.025

Relative fat mass is a better tool to diagnose high adiposity when compared to body mass index in young male adults: A cross-section study

Clinical Nutrition ESPEN / Feb 01, 2021

Corrêa, C. R., Formolo, N. P. S., Dezanetti, T., Speretta, G. F. F., & Nunes, E. A. (2021). Relative fat mass is a better tool to diagnose high adiposity when compared to body mass index in young male adults: A cross-section study. Clinical Nutrition ESPEN, 41, 225–233. https://doi.org/10.1016/j.clnesp.2020.12.009

Impact of combined long-term fructose and prednisolone intake on glucose and lipid homeostasis in rats: benefits of intake interruption or fish oil administration

The Journal of Nutritional Biochemistry / Apr 01, 2021

Santos, C. dos, da Silva, J. S., Brunetta, H. S., Chagas, T. R., Zoccal, D. B., Nunes, E. A., & Rafacho, A. (2021). Impact of combined long-term fructose and prednisolone intake on glucose and lipid homeostasis in rats: benefits of intake interruption or fish oil administration. The Journal of Nutritional Biochemistry, 90, 108572. https://doi.org/10.1016/j.jnutbio.2020.108572

Understanding the effects of nutrition and post-exercise nutrition on skeletal muscle protein turnover: Insights from stable isotope studies

Clinical Nutrition Open Science / Apr 01, 2021

Joanisse, S., McKendry, J., Lim, C., Nunes, E. A., Stokes, T., Mcleod, J. C., & Phillips, S. M. (2021). Understanding the effects of nutrition and post-exercise nutrition on skeletal muscle protein turnover: Insights from stable isotope studies. Clinical Nutrition Open Science, 36, 56–77. https://doi.org/10.1016/j.nutos.2021.01.005

Effect of mate tea consumption on rapid force production after eccentric exercise: a randomized, controlled, crossover study

Sport Sciences for Health / Jul 09, 2020

Moura, B. M., Panza, V. P., Brunetta, H. S., Tamborindeguy, A. C., de Oliveira, M. V., Sakugawa, R. L., Nunes, E. A., da Silva, E. L., & Diefenthaeler, F. (2020). Effect of mate tea consumption on rapid force production after eccentric exercise: a randomized, controlled, crossover study. Sport Sciences for Health, 16(3), 571–581. https://doi.org/10.1007/s11332-020-00669-9

Association of physical activity and sedentary behavior at school with cardiovascular risk factors in adolescents

Revista Brasileira de Cineantropometria & Desempenho Humano / Jan 01, 2020

Santos, P. C. dos, Lima, L. R. A. de, Costa, B. G. G. da, Martins, C. R., Minatto, G., Berria, J., Nunes, E. A., Petroski, E. L., & Silva, K. S. da. (2020). Association of physical activity and sedentary behavior at school with cardiovascular risk factors in adolescents. Revista Brasileira de Cineantropometria & Desempenho Humano, 22. https://doi.org/10.1590/1980-0037.2020v22e72397

Behavioral, cardiovascular and endocrine alterations induced by chronic stress in rats fed a high-fat diet

Physiology & Behavior / Sep 01, 2020

Batschauer, T., Cordeiro, J. M., Simas, B. B., Brunetta, H. S., Souza, R. M., Nunes, E. A., Reis, W. L., Moreira, E. L. G., Crestani, C. C., Santos, A. R. S., & Speretta, G. F. (2020). Behavioral, cardiovascular and endocrine alterations induced by chronic stress in rats fed a high-fat diet. Physiology & Behavior, 223, 113013. https://doi.org/10.1016/j.physbeh.2020.113013

Fructose Intake Impairs Cortical Antioxidant Defenses Allied to Hyperlocomotion in Middle-Aged C57BL/6 Female Mice

Neurochemical Research / Sep 23, 2020

dos Santos, B., Schmitz, A. E., de Almeida, G. R. L., de Souza, L. F., Szczepanik, J. C., Nunes, E. A., Brunetta, H. S., Mack, J. M., Prediger, R. D., Cunha, M. P., & Dafre, A. L. (2020). Fructose Intake Impairs Cortical Antioxidant Defenses Allied to Hyperlocomotion in Middle-Aged C57BL/6 Female Mice. Neurochemical Research, 45(12), 2868–2883. https://doi.org/10.1007/s11064-020-03135-7

Fish oil decreases the severity of treatment-related adverse events in gastrointestinal cancer patients undergoing chemotherapy: A randomized, placebo-controlled, triple-blind clinical trial

Clinical Nutrition ESPEN / Jun 01, 2019

Camargo, C. de Q., Mocellin, M. C., Brunetta, H. S., Chagas, T. R., Fabre, M. E. de S., Trindade, E. B. S. de M., Silva, E. L. da, & Nunes, E. A. (2019). Fish oil decreases the severity of treatment-related adverse events in gastrointestinal cancer patients undergoing chemotherapy: A randomized, placebo-controlled, triple-blind clinical trial. Clinical Nutrition ESPEN, 31, 61–70. https://doi.org/10.1016/j.clnesp.2019.02.015

Aerobic fitness and physical activity are inversely associated with body fat, dyslipidemia and inflammatory mediators in children and adolescents living with HIV

Journal of Sports Sciences / Jun 08, 2018

de Lima, L. R. A., Back, I. de C., Nunes, E. A., Silva, D. A. S., & Petroski, E. L. (2018). Aerobic fitness and physical activity are inversely associated with body fat, dyslipidemia and inflammatory mediators in children and adolescents living with HIV. Journal of Sports Sciences, 37(1), 50–58. https://doi.org/10.1080/02640414.2018.1481724

Assessing the mechanistic target of rapamycin complex-1 pathway in response to resistance exercise and feeding in human skeletal muscle by multiplex assay

Applied Physiology, Nutrition, and Metabolism / Sep 01, 2018

McGlory, C., Nunes, E. A., Oikawa, S. Y., Tsakiridis, E., & Phillips, S. M. (2018). Assessing the mechanistic target of rapamycin complex-1 pathway in response to resistance exercise and feeding in human skeletal muscle by multiplex assay. Applied Physiology, Nutrition, and Metabolism, 43(9), 945–949. https://doi.org/10.1139/apnm-2017-0852

Cardiovascular and metabolic consequences of the association between chronic stress and high-fat diet in rats

Stress / Feb 10, 2018

Simas, B. B., Nunes, E. A., Crestani, C. C., & Speretta, G. F. (2018). Cardiovascular and metabolic consequences of the association between chronic stress and high-fat diet in rats. Stress, 21(3), 247–256. https://doi.org/10.1080/10253890.2018.1437413

Glucose homeostasis in two degrees of sepsis lethality induced by caecum ligation and puncture in mice

International Journal of Experimental Pathology / Dec 01, 2017

Ferreira, F. B. D., dos Santos, C., Bruxel, M. A., Nunes, E. A., Spiller, F., & Rafacho, A. (2017). Glucose homeostasis in two degrees of sepsis lethality induced by caecum ligation and puncture in mice. International Journal of Experimental Pathology, 98(6), 329–340. Portico. https://doi.org/10.1111/iep.12255

Impact of Fish Oil Supplementation and Interruption of Fructose Ingestion on Glucose and Lipid Homeostasis of Rats Drinking Different Concentrations of Fructose

BioMed Research International / Jan 01, 2017

Sulis, P. M., Motta, K., Barbosa, A. M., Besen, M. H., da Silva, J. S., Nunes, E. A., & Rafacho, A. (2017). Impact of Fish Oil Supplementation and Interruption of Fructose Ingestion on Glucose and Lipid Homeostasis of Rats Drinking Different Concentrations of Fructose. BioMed Research International, 2017, 1–16. https://doi.org/10.1155/2017/4378328

Fish oil supplementation attenuates changes in plasma lipids caused by dexamethasone treatment in rats

Applied Physiology, Nutrition, and Metabolism / Apr 01, 2016

Barbosa, A. M., Francisco, P. de C., Motta, K., Chagas, T. R., dos Santos, C., Rafacho, A., & Nunes, E. A. (2016). Fish oil supplementation attenuates changes in plasma lipids caused by dexamethasone treatment in rats. Applied Physiology, Nutrition, and Metabolism, 41(4), 382–390. https://doi.org/10.1139/apnm-2015-0487

INTERVAL TRAINING IS INSUFFICIENT TO ATTENUATE METABOLIC DISTURBANCES IN DIABETIC RATS

Revista Brasileira de Medicina do Esporte / Oct 01, 2016

Rocha, R. E. R. da, Nunes, E. A., Venera, G. D., & Fernandes, L. C. (2016). INTERVAL TRAINING IS INSUFFICIENT TO ATTENUATE METABOLIC DISTURBANCES IN DIABETIC RATS. Revista Brasileira de Medicina Do Esporte, 22(5), 393–397. https://doi.org/10.1590/1517-869220162205154777

Glucose homoeostasis in rats exposed to acute intermittent hypoxia

Acta Physiologica / Jun 08, 2013

Rafacho, A., Gonçalves-Neto, L. M., Ferreira, F. B. D., Protzek, A. O. P., Boschero, A. C., Nunes, E. A., & Zoccal, D. B. (2013). Glucose homoeostasis in rats exposed to acute intermittent hypoxia. Acta Physiologica, 209(1), 77–89. https://doi.org/10.1111/apha.12118

Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats

Applied Physiology, Nutrition, and Metabolism / Nov 01, 2013

Nunes, E. A., Gonçalves-Neto, L. M., Ferreira, F. B. D., dos Santos, C., Fernandes, L. C., Boschero, A. C., Calder, P. C., & Rafacho, A. (2013). Glucose intolerance induced by glucocorticoid excess is further impaired by co-administration with β-hydroxy-β-methylbutyrate in rats. Applied Physiology, Nutrition, and Metabolism, 38(11), 1137–1146. https://doi.org/10.1139/apnm-2012-0456

Relationship between Acute Phase Proteins and Serum Fatty Acid Composition in Morbidly Obese Patients

Disease Markers / Jan 01, 2013

Fernandes, R., Beserra, B. T. S., Cunha, R. S. G., Hillesheim, E., Camargo, C. de Q., Pequito, D. C. T., de Castro, I. C., Fernandes, L. C., Nunes, E. A., & Trindade, E. B. S. de M. (2013). Relationship between Acute Phase Proteins and Serum Fatty Acid Composition in Morbidly Obese Patients. Disease Markers, 35, 105–112. https://doi.org/10.1155/2013/913715

β-Hydroxy-β-methylbutyrate modifies human peripheral blood mononuclear cell proliferation and cytokine production in vitro

Nutrition / Jan 01, 2011

Nunes, E. A., Lomax, A. R., Noakes, P. S., Miles, E. A., Fernandes, L. C., & Calder, P. C. (2011). β-Hydroxy-β-methylbutyrate modifies human peripheral blood mononuclear cell proliferation and cytokine production in vitro. Nutrition, 27(1), 92–99. https://doi.org/10.1016/j.nut.2009.12.008

Lymphocytes transfer [¹⁴C]‐labeled fatty acids to skeletal muscle in culture; modulation by exercise

Cell Biochemistry and Function / May 26, 2010

Brito, G. A. P., Nunes, E. A., Nogata, C., Yamazaky, R. K., Naliwaiko, K., Curi, R., & Fernandes, L. C. (2010). Lymphocytes transfer [14C]‐labeled fatty acids to skeletal muscle in culture; modulation by exercise. Cell Biochemistry and Function, 28(4), 278–282. Portico. https://doi.org/10.1002/cbf.1652

Walker-256 tumor growth is inhibited by the independent or associative chronic ingestion of shark liver and fish oil: a response linked by the increment of peritoneal macrophages nitrite production in Wistar rats

Nutrition Research / Nov 01, 2010

Belo, S. R. B., Iagher, F., Bonatto, S. J., Naliwaiko, K., Calder, P. C., Nunes, E. A., & Fernandes, L. C. (2010). Walker-256 tumor growth is inhibited by the independent or associative chronic ingestion of shark liver and fish oil: a response linked by the increment of peritoneal macrophages nitrite production in Wistar rats. Nutrition Research, 30(11), 770–776. https://doi.org/10.1016/j.nutres.2010.09.015

Neutrophil response of anaerobic jump trained diabetic rats

European Journal of Applied Physiology / Sep 10, 2008

de Souza, C. F., Machado, A. F., Bonatto, S. J. R., Grando, F. C. C., Pessini, C., Alves, L. E., de Lima, C., de Brito, G. A. P., Nunes, E. A., & Fernandes, L. C. (2008). Neutrophil response of anaerobic jump trained diabetic rats. European Journal of Applied Physiology, 104(6), 1079–1086. https://doi.org/10.1007/s00421-008-0865-9

Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation

Prostaglandins, Leukotrienes and Essential Fatty Acids / Feb 01, 2007

Mund, R. C., Pizato, N., Bonatto, S., Nunes, E. A., Vicenzi, T., Tanhoffer, R., de Oliveira, H. H. P., Curi, R., Calder, P. C., & Fernandes, L. C. (2007). Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins, Leukotrienes and Essential Fatty Acids, 76(2), 113–120. https://doi.org/10.1016/j.plefa.2006.11.008

Fish oil alters T-lymphocyte proliferation and macrophage responses in Walker 256 tumor-bearing rats

Nutrition / Apr 01, 2006

Pizato, N., Bonatto, S., Piconcelli, M., de Souza, L. M., Sassaki, G. L., Naliwaiko, K., Nunes, E. A., Curi, R., Calder, P. C., & Fernandes, L. C. (2006). Fish oil alters T-lymphocyte proliferation and macrophage responses in Walker 256 tumor-bearing rats. Nutrition, 22(4), 425–432. https://doi.org/10.1016/j.nut.2005.11.001

The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle

Molecular and Cellular Biochemistry / May 01, 2005

Yamazaki, R. K., Hirabara, S. M., Tchaikovski, O., Lopes, M. C. P., Nogata, C., Aikawa, J., Nunes, E. A., Tanhoffer, R. A., Lissa, M. D., & Fernandes, L. C. (2005). The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle. Molecular and Cellular Biochemistry, 273(1–2), 145–150. https://doi.org/10.1007/s11010-005-8265-5

Tumor growth reduction in Walker 256 tumor-bearing rats performing anaerobic exercise: participation of Bcl-2, Bax, apoptosis, and peroxidation

Applied Physiology, Nutrition, and Metabolism / Aug 01, 2011

de Lima, C., Alves, L., Iagher, F., Machado, A. F., Kryczyk, M., Yamazaki, R. K., Brito, G. A. P., Nunes, E. A., Naliwaiko, K., & Fernandes, L. C. (2011). Tumor growth reduction in Walker 256 tumor-bearing rats performing anaerobic exercise: participation of Bcl-2, Bax, apoptosis, and peroxidation. Applied Physiology, Nutrition, and Metabolism, 36(4), 533–538. https://doi.org/10.1139/h11-047

See Full Profile

Dr. Shilpa Patil, Ph.D

Vancouver, British Columbia, Canada

PhD & Postdoc level expertise in Cancer Research

Most Relevant Research Interests

Endocrinology, Diabetes and Metabolism

Gastroenterology

Other Research Interests (9)

About

Dr. Shilpa Patil is a highly experienced cancer researcher with a strong background in Preclinical studies. She received her Ph.D. in Molecular Medicine from the University of Göttingen in 2020, where she focused on developing novel treatments for pancreatic cancer. Prior to that, she completed her MSc in Regenerative Medicine from Manipal University in 2014 and her BSc in Biotechnology from the same institution in 2012. With over 6 years of research experience, Dr. Patil has worked at prestigious institutions such as the University of British Columbia, University of Göttingen and JNCASR. Her expertise lies in the areas of cancer biology, epigenetics, cell and molecular biology, and regenerative medicine. She has published numerous research articles in reputed journals and has presented her work at various international conferences. Dr. Patil is a dedicated and passionate scientist, committed to using her knowledge and skills to contribute to the fight against cancer. She is driven by her curiosity to unravel complex biological processes and her desire to make a positive impact in the field of cancer research. She is also driven to bridge the academia-industry gap.

Most Relevant Publications (9+)

20 total publications

Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites

EBioMedicine / Feb 01, 2019

Patzak, M. S., Kari, V., Patil, S., Hamdan, F. H., Goetze, R. G., Brunner, M., Gaedcke, J., Kitz, J., Jodrell, D. I., Richards, F. M., Pilarsky, C., Gruetzmann, R., Rümmele, P., Knösel, T., Hessmann, E., Ellenrieder, V., Johnsen, S. A., & Neesse, A. (2019). Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites. EBioMedicine, 40, 394–405. https://doi.org/10.1016/j.ebiom.2019.01.037

Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models

Journal of Visualized Experiments / Apr 07, 2018

Goetze, R.-G., Buchholz, S. M., Patil, S., Petzold, G., Ellenrieder, V., Hessmann, E., & Neesse, A. (2018). Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models. Journal of Visualized Experiments, 134. https://doi.org/10.3791/56979-v

Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation

Biochimica et Biophysica Acta (BBA) - General Subjects / Aug 01, 2018

Kaypee, S., Sahadevan, S. A., Sudarshan, D., Halder Sinha, S., Patil, S., Senapati, P., Kodaganur, G. S., Mohiyuddin, A., Dasgupta, D., & Kundu, T. K. (2018). Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(8), 1729–1741. https://doi.org/10.1016/j.bbagen.2018.05.003

Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes

Visceral Medicine / Dec 27, 2021

Patil, S., Dou, Y., & Kopp, J. L. (2021). Cell Type of Pancreatic Ductal Adenocarcinoma Origin: Implications for Prognosis and Clinical Outcomes. Visceral Medicine, 38(1), 4–10. Portico. https://doi.org/10.1159/000520946

NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming

Cellular and Molecular Gastroenterology and Hepatology / Jan 01, 2023

Zhang, Z., Wang, X., Hamdan, F. H., Likhobabina, A., Patil, S., Aperdannier, L., Sen, M., Traub, J., Neesse, A., Fischer, A., Papantonis, A., Singh, S. K., Ellenrieder, V., Johnsen, S. A., & Hessmann, E. (2023). NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming. Cellular and Molecular Gastroenterology and Hepatology, 15(5), 1219–1246. https://doi.org/10.1016/j.jcmgh.2023.01.015

EZH2 controls PDAC plasticity by regulating differentiation genes

Pancreatology / Jun 01, 2019

Patil, S., Najafova, Z., Kari, V., Wang, X., Bohnenberger, H., Kopp, W., Spitalieri, J., Neesse, A., Ellenrieder, V., Johnsen, S., & Hessmann, E. (2019). EZH2 controls PDAC plasticity by regulating differentiation genes. Pancreatology, 19, S11. https://doi.org/10.1016/j.pan.2019.05.021

Impact of cytosolic 5'-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer

Pancreatology / Jun 01, 2018

Patzak, M. S., Hessmann, E., Kari, V., Kitz, J., Patil, S., Richards, F. M., Jodrell, D. I., Johnsen, S. A., Ellenrieder, V., & Neesse, A. (2018). Impact of cytosolic 5’-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer. Pancreatology, 18(4), S91. https://doi.org/10.1016/j.pan.2018.05.247

Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity

Pancreatology / Jul 01, 2017

Patil, S., Witte, H., Neesse, A., Johnsen, S., Ellenrieder, V., & Hessmann, E. (2017). Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity. Pancreatology, 17(3), S41. https://doi.org/10.1016/j.pan.2017.05.128

Utilizing High Resolution Ultrasound to Monitor Tumor Onset and Growth in Genetically Engineered Pancreatic Cancer Models

Journal of Visualized Experiments / Apr 07, 2018

See Full Profile

Joshua adekunle Babalola, Ph.D.

Graz

A scientist interested in translating life science skills into solving real life problems relating to microbes, aging, neurodegenerative and metabolic diseases. An advocate of inclusive science and life style changes.

Most Relevant Research Interests

Aging

Neurodegeneration

Developmental Neuroscience

Geriatrics and Gerontology

Joshua Babalola completed his doctoral studies recently during which he investigated the combinational effects of Type 2 diabetes and protein post translational modification in the pathophysiology of Alzheimer's disease. <br> Joshua is interested in translating life science skills into solving real life problems relating to microbial infections, aging, metabolic dysfunctions and neurodegenerative diseases. Aside these, he advocates for inclusive science and lifestyle changes. Joshua's educational background includes an MSc in Medical Microbiology from Hallym University, South Korea and a PhD in Human Medicine from Medical University of Graz, Austria. He also holds a BSc in Microbiology from Ekiti State University, Nigeria. In Joshua's leisure, he communicates science relating to healthy lifestyle modifications and Dementia via his social media handles.

Other Research Interests (5)

Dementia

Life style changes

Metabolic dysfunction

Neurology (clinical)

Epidemiology

About

Most Relevant Publications (4+)

9 total publications

Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer’s disease-related blood brain barrier dysfunction and inflammation

Brain Research / Nov 01, 2023

Babalola, J. A., Lang, M., George, M., Stracke, A., Tam-Amersdorfer, C., Itxaso, I., Lucija, D., Tadic, J., Schilcher, I., Loeffler, T., Flunkert, S., Prokesch, M., Leitinger, G., Lass, A., Hutter-Paier, B., Panzenboeck, U., & Hoefler, G. (2023). Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer’s disease-related blood brain barrier dysfunction and inflammation. Brain Research, 1819, 148518. https://doi.org/10.1016/j.brainres.2023.148518

Sex and genotype dependent differences in amyloid beta levels and lipid metabolism in type 2 diabetic APPxhQC transgenic mice

Alzheimer's & Dementia / Dec 01, 2023

Babalola, J. A., Lang, M., George, M., Stracke, A., Loeffler, T., Schilcher, I., Flunkert, S., Neddens, J., Prokesch, M., Leitinger, G., Lass, A., Hoefler, G., & Hutter‐Paier, B. (2023). Sex and genotype dependent differences in amyloid beta levels and lipid metabolism in type 2 diabetic APPxhQC transgenic mice. Alzheimer’s & Dementia, 19(S12). Portico. https://doi.org/10.1002/alz.079077

Establishing a Type 2 Diabetes phenotype in APPxhQC transgenic mice expressing N‐terminally modified pGlu Aβ peptides.

Alzheimer's & Dementia / Dec 01, 2022

Babalola, J. A., Loeffler, T., Schilcher, I., Breznik, L., Rabl, R., Sideromenos, S., Flunkert, S., Prokesch, M., Hoefler, G., & Hutter‐Paier, B. (2022). Establishing a Type 2 Diabetes phenotype in APPxhQC transgenic mice expressing N‐terminally modified pGlu Aβ peptides. Alzheimer’s & Dementia, 18(S3). Portico. https://doi.org/10.1002/alz.066646

Liver-X receptor activation attenuates oxysterol induced inflammatory response in human feto-placental endothelial cells in gestational diabetes mellitus

Placenta / Sep 01, 2021

Geroge, M., Lang, M., Tam-Amersdorfer, C., Joshua, B., & Wadsack, C. (2021). Liver-X receptor activation attenuates oxysterol induced inflammatory response in human feto-placental endothelial cells in gestational diabetes mellitus. Placenta, 112, e37. https://doi.org/10.1016/j.placenta.2021.07.121

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Dr. Hannah Actor-Engel, Ph.D.

Brooklyn, New York, United States of America

University of Colorado Anschutz

Most Relevant Research Interests

Histology

Biomedical scientist with Ph.D. in Neuroscience. Expertise in neuroscience, molecular biology, neurodegeneration, and fluorescence microscopy. Experienced researcher, problem-solver, and medical writer.

Other Research Interests (2)

Molecular neuroscience

Anatomy

About

Most Relevant Publications (6+)

8 total publications

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise

Brain Structure and Function / Dec 03, 2016

Chen, Y.-W., Actor-Engel, H., Sherpa, A. D., Klingensmith, L., Chowdhury, T. G., & Aoki, C. (2016). NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise. Brain Structure and Function, 222(5), 2271–2294. https://doi.org/10.1007/s00429-016-1341-7

α4-GABAA receptors of hippocampal pyramidal neurons are associated with resilience against activity-based anorexia for adolescent female mice but not for males

Molecular and Cellular Neuroscience / Jul 01, 2018

Chen, Y.-W., Actor-Engel, H., & Aoki, C. (2018). α4-GABAA receptors of hippocampal pyramidal neurons are associated with resilience against activity-based anorexia for adolescent female mice but not for males. Molecular and Cellular Neuroscience, 90, 33–48. https://doi.org/10.1016/j.mcn.2018.04.008

Suppression of food restriction‐evoked hyperactivity in activity‐based anorexia animal model through glutamate transporters GLT‐1 at excitatory synapses in the hippocampus

Synapse / Mar 16, 2021

Bilash, O. M., Actor‐Engel, H. S., Sherpa, A. D., Chen, Y., & Aoki, C. (2021). Suppression of food restriction‐evoked hyperactivity in activity‐based anorexia animal model through glutamate transporters GLT‐1 at excitatory synapses in the hippocampus. Synapse, 75(7). Portico. https://doi.org/10.1002/syn.22197

Correction to: NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise

Brain Structure and Function / Jan 31, 2020

Chen, Y.-W., Actor-Engel, H., Sherpa, A. D., Klingensmith, L., Chowdhury, T. G., & Aoki, C. (2020). Correction to: NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise. Brain Structure and Function, 225(3), 1165–1165. https://doi.org/10.1007/s00429-020-02030-9

Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses

Cell Reports / Nov 01, 2023

Olah, S. S., Kareemo, D. J., Buchta, W. C., Sinnen, B. L., Miller, C. N., Actor-Engel, H. S., Gookin, S. E., Winborn, C. S., Kleinjan, M. S., Crosby, K. C., Aoto, J., Smith, K. R., & Kennedy, M. J. (2023). Acute reorganization of postsynaptic GABAA receptors reveals the functional impact of molecular nanoarchitecture at inhibitory synapses. Cell Reports, 42(11), 113331. https://doi.org/10.1016/j.celrep.2023.113331

AMPA and GABAA receptor nanodomains assemble in the absence of synaptic neurotransmitter release

Frontiers in Molecular Neuroscience / Aug 03, 2023

Ramsay, H. J., Gookin, S. E., Ramsey, A. M., Kareemo, D. J., Crosby, K. C., Stich, D. G., Olah, S. S., Actor-Engel, H. S., Smith, K. R., & Kennedy, M. J. (2023). AMPA and GABAA receptor nanodomains assemble in the absence of synaptic neurotransmitter release. Frontiers in Molecular Neuroscience, 16. https://doi.org/10.3389/fnmol.2023.1232795

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Aayudh Das, Ph.D.

Boston, Massachusetts, United States of America

Scientist at Garuda therapeutics, specialized in Genomics and Computational Biology

Most Relevant Research Interests

Genomics

Computational Biology

Plant Science

Immunology and Allergy

Microbiology (medical)

Ecology, Evolution, Behavior and Systematics

Biotechnology

Other Research Interests (7)

Transcriptomics

Proteomics

Metabolomics

Ecology

And 2 more

About

I am a dedicated Scientist-I at Garuda Therapeutics, where I specialize in computational biology and genomics within the R&D department. My work primarily revolves around developing and optimizing pipelines for variant calling using Strelka2 and GATK4 with Whole Genome Sequencing (WGS) to identify oncogenes in human induced pluripotent stem cells (iPSCs). This involves extensive work in the qualification and validation of these pipelines for regulatory filings, as well as leveraging databases such as ClinVar, COSMIC, and DepMap to craft targeted oncogenes panels for deep sequencing. I also apply Next-Generation Sequencing (NGS) for downstream sequencing to validate CRISPR knockouts, including the identification and validation of CRISPR off-targets using techniques like rhAMPseq and Induce-seq. Additionally, my expertise extends to single-cell sequencing analysis and understanding structural variants with Optical Genome Mapping (Bionano). Prior to joining Garuda Therapeutics, I completed a postdoctoral fellowship in computational biology at Pennsylvania State University, where I honed my skills in identifying climate-adaptive variants and conducted Genome-Wide Association Studies (GWAS) to uncover resistance genes against parasites and other stressors. My academic journey began at the University of Vermont, where I explored abiotic stress resistance genes using transcriptomics and developed a robust understanding of RNA-seq data analysis, from assembly to gene annotation. My work is driven by a passion for leveraging computational and genomics tools to address pressing challenges in biology and healthcare, combining my rigorous academic training with a practical, solution-oriented approach to research and development.

Most Relevant Publications (8+)

10 total publications

Metabolomic Profiling of Soybeans (Glycine max L.) Reveals the Importance of Sugar and Nitrogen Metabolism under Drought and Heat Stress

Plants / May 25, 2017

Das, A., Rushton, P., & Rohila, J. (2017). Metabolomic Profiling of Soybeans (Glycine max L.) Reveals the Importance of Sugar and Nitrogen Metabolism under Drought and Heat Stress. Plants, 6(4), 21. https://doi.org/10.3390/plants6020021

Leaf Proteome Analysis Reveals Prospective Drought and Heat Stress Response Mechanisms in Soybean

BioMed Research International / Jan 01, 2016

Das, A., Eldakak, M., Paudel, B., Kim, D.-W., Hemmati, H., Basu, C., & Rohila, J. S. (2016). Leaf Proteome Analysis Reveals Prospective Drought and Heat Stress Response Mechanisms in Soybean. BioMed Research International, 2016, 1–23. https://doi.org/10.1155/2016/6021047

Unraveling Key Metabolomic Alterations in Wheat Embryos Derived from Freshly Harvested and Water-Imbibed Seeds of Two Wheat Cultivars with Contrasting Dormancy Status

Frontiers in Plant Science / Jul 12, 2017

Das, A., Kim, D.-W., Khadka, P., Rakwal, R., & Rohila, J. S. (2017). Unraveling Key Metabolomic Alterations in Wheat Embryos Derived from Freshly Harvested and Water-Imbibed Seeds of Two Wheat Cultivars with Contrasting Dormancy Status. Frontiers in Plant Science, 8. https://doi.org/10.3389/fpls.2017.01203

A Quantitative Proteomics View on the Function of Qfhb1, a Major QTL for Fusarium Head Blight Resistance in Wheat

Pathogens / Jun 22, 2018

Eldakak, M., Das, A., Zhuang, Y., Rohila, J., Glover, K., & Yen, Y. (2018). A Quantitative Proteomics View on the Function of Qfhb1, a Major QTL for Fusarium Head Blight Resistance in Wheat. Pathogens, 7(3), 58. https://doi.org/10.3390/pathogens7030058

Proteomic Responses of Switchgrass and Prairie Cordgrass to Senescence

Frontiers in Plant Science / Mar 14, 2016

Paudel, B., Das, A., Tran, M., Boe, A., Palmer, N. A., Sarath, G., Gonzalez-Hernandez, J. L., Rushton, P. J., & Rohila, J. S. (2016). Proteomic Responses of Switchgrass and Prairie Cordgrass to Senescence. Frontiers in Plant Science, 7. https://doi.org/10.3389/fpls.2016.00293

Variation in climatic tolerance, but not stomatal traits, partially explains Pooideae grass species distributions

Annals of Botany / Mar 27, 2021

Das, A., Prakash, A., Dedon, N., Doty, A., Siddiqui, M., & Preston, J. C. (2021). Variation in climatic tolerance, but not stomatal traits, partially explains Pooideae grass species distributions. Annals of Botany, 128(1), 83–95. https://doi.org/10.1093/aob/mcab046

Investigation of the Cardiotonic Steroids, Marinobufagenin and Resibufogenin, in the Acute Respiratory Distress Syndrome

The FASEB Journal / Apr 01, 2016

Abbas, M. M. K., Chen, Q., Das, A., Oliver, J., Jiang, W., Moorthy, B., Patel, B., Morin, K., & Puschett, J. (2016). Investigation of the Cardiotonic Steroids, Marinobufagenin and Resibufogenin, in the Acute Respiratory Distress Syndrome. The FASEB Journal, 30(S1). Portico. https://doi.org/10.1096/fasebj.30.1_supplement.982.4

Testing the chilling‐ before drought‐tolerance hypothesis in Pooideae grasses

Molecular Ecology / Dec 07, 2022

Das, A., Dedon, N., Enders, D. J., Fjellheim, S., & Preston, J. C. (2022). Testing the chilling‐ before drought‐tolerance hypothesis in Pooideae grasses. Molecular Ecology, 32(4), 772–785. Portico. https://doi.org/10.1111/mec.16794

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Elena Shersher, Ph.D.

Miami

Cancer researcher at University of Miami

Most Relevant Research Interests

Elena Shersher, Ph.D. is a highly skilled and experienced biochemist with a strong background in cancer research. She received her Ph.D. in Biochemistry from Florida International University in 2016, where she was a recipient of a prestigious Presidential fellowship. After completing her Ph.D., Elena continued her career as a clinical program development lead and coordinator at a CRO. In 2017, Elena joined a cancer research team at the University of Miami as a researcher. In this role, she utilized her expertise in advanced laboratory techniques and data analysis to study the role of specific proteins in cancer cell signaling in order to identify promising molecular targets for therapeutic intervention. Elena's research has been published in several prestigious scientific journals, and she has presented her findings at numerous conferences. In addition to her research, Elena is also passionate about mentoring and teaching the next generation of scientists. She has served as a mentor and advisor to undergraduate and graduate students, helping them develop their research skills and guiding them in their academic and career paths. Elena's dedication and contributions to the field of cancer research have made her a valuable asset to the scientific community. With her expertise and experience, she continues to make significant advancements in understanding and treating cancer, bringing hope to those affected by this devastating disease.

Other Research Interests (4)

Cancer Research

Biochemistry

Drug discovery

Cancer cell signaling

About

Most Relevant Publications (1+)

4 total publications

NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis

Cell Communication and Signaling / Sep 22, 2021

Shersher, E., Lahiry, M., Alvarez-Trotta, A., Diluvio, G., Robbins, D. J., Shiekhattar, R., & Capobianco, A. J. (2021). NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. Cell Communication and Signaling, 19(1). https://doi.org/10.1186/s12964-021-00776-1

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Susan Song, MD/PhD

Pittsburgh, Pennsylvania, United States of America

Research Assistant Professor in Neuroscience at University of Pittsburgh

Most Relevant Research Interests

Developmental Neuroscience

Other Research Interests (12)

microglia

white matter

neurodegenerative disease

Neurology

Neurology (clinical)

And 7 more

About

Susan Song, MD/PhD, is a highly accomplished neuroscientist, with extensive education and experience in the field. She received her MD/PhD in Neurology and Neuroscience from Southern Medical University in 2015, where she conducted groundbreaking research on the molecular mechanisms of neurodegenerative diseases. Following this, she completed a post-doctoral fellowship in Neuroscience at the University of Pittsburgh, where she continued to excel in her research and received numerous awards and grants for her work. Dr. Song's expertise lies in studying the underlying causes and potential treatments for various neurological diseases, such as ischemic stroke, traumatic brain injury, glioblastoma, Alzheimer's disease, and multiple sclerosis. She has a deep understanding of the brain and nervous system, and is constantly seeking new ways to unravel the complexities of these diseases. Dr. Song has held several prestigious positions throughout her career, including her current position as Research Assistant Professor at the University of Pittsburgh. She has published numerous articles in top scientific journals and presented her research at international conferences. Her findings have contributed greatly to the field of neurology and have the potential to improve the lives of millions of people suffering from neurological disorders. Overall, Dr. Song is a highly respected and accomplished physician-scientist who is making significant contributions to the field of neurology. With her extensive education, diverse experience, and unwavering dedication to her patients, she is a true leader in the field and a valuable asset to the medical community.

Most Relevant Publications (13+)

20 total publications

Selective knockout of astrocytic Na⁺/H⁺ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke

Glia / Sep 19, 2017

Begum, G., Song, S., Wang, S., Zhao, H., Bhuiyan, M. I. H., Li, E., Nepomuceno, R., Ye, Q., Sun, M., Calderon, M. J., Stolz, D. B., St. Croix, C., Watkins, S. C., Chen, Y., He, P., Shull, G. E., & Sun, D. (2017). Selective knockout of astrocytic Na+/H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke. Glia, 66(1), 126–144. Portico. https://doi.org/10.1002/glia.23232

Ion channels and transporters in microglial function in physiology and brain diseases

Neurochemistry International / Jan 01, 2021

Luo, L., Song, S., Ezenwukwa, C. C., Jalali, S., Sun, B., & Sun, D. (2021). Ion channels and transporters in microglial function in physiology and brain diseases. Neurochemistry International, 142, 104925. https://doi.org/10.1016/j.neuint.2020.104925

Roles of glial ion transporters in brain diseases

Glia / Aug 16, 2019

Song, S., Luo, L., Sun, B., & Sun, D. (2019). Roles of glial ion transporters in brain diseases. Glia, 68(3), 472–494. Portico. https://doi.org/10.1002/glia.23699

Selective role of Na⁺/H⁺ exchanger in Cx3cr1⁺ microglial activation, white matter demyelination, and post‐stroke function recovery

Glia / Jul 25, 2018

Song, S., Wang, S., Pigott, V. M., Jiang, T., Foley, L. M., Mishra, A., Nayak, R., Zhu, W., Begum, G., Shi, Y., Carney, K. E., Hitchens, T. K., Shull, G. E., & Sun, D. (2018). Selective role of Na+/H+ exchanger in Cx3cr1+ microglial activation, white matter demyelination, and post‐stroke function recovery. Glia, 66(11), 2279–2298. Portico. https://doi.org/10.1002/glia.23456

Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function

Journal of Neuroinflammation / Aug 28, 2021

Liu, Q., Bhuiyan, M. I. H., Liu, R., Song, S., Begum, G., Young, C. B., Foley, L. M., Chen, F., Hitchens, T. K., Cao, G., Chattopadhyay, A., He, L., & Sun, D. (2021). Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function. Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02234-8

The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases

Aging and disease / Jan 01, 2019

Huang, H., Song, S., Banerjee, S., Jiang, T., Zhang, J., Kahle, K. T., Sun, D., & Zhang, Z. (2019). The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases. Aging and Disease, 10(3), 626. https://doi.org/10.14336/ad.2018.0928

Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice

Communications Biology / Jan 11, 2022

Song, S., Yu, L., Hasan, M. N., Paruchuri, S. S., Mullett, S. J., Sullivan, M. L. G., Fiesler, V. M., Young, C. B., Stolz, D. B., Wendell, S. G., & Sun, D. (2022). Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice. Communications Biology, 5(1). https://doi.org/10.1038/s42003-021-02984-4

Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury

Journal of Neuroinflammation / Oct 05, 2022

Song, S., Hasan, M. N., Yu, L., Paruchuri, S. S., Bielanin, J. P., Metwally, S., Oft, H. C. M., Fischer, S. G., Fiesler, V. M., Sen, T., Gupta, R. K., Foley, L. M., Hitchens, T. K., Dixon, C. E., Cambi, F., Sen, N., & Sun, D. (2022). Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury. Journal of Neuroinflammation, 19(1). https://doi.org/10.1186/s12974-022-02608-6

Inhibition of Na⁺/H⁺ exchanger modulates microglial activation and scar formation following microelectrode implantation

Journal of Neural Engineering / Mar 19, 2021

Dubaniewicz, M., Eles, J. R., Lam, S., Song, S., Cambi, F., Sun, D., Wellman, S. M., & Kozai, T. D. Y. (2021). Inhibition of Na+/H+ exchanger modulates microglial activation and scar formation following microelectrode implantation. Journal of Neural Engineering, 18(4), 045001. https://doi.org/10.1088/1741-2552/abe8f1

Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke

International Journal of Molecular Sciences / Aug 27, 2023

Metwally, S. A. H., Paruchuri, S. S., Yu, L., Capuk, O., Pennock, N., Sun, D., & Song, S. (2023). Pharmacological Inhibition of NHE1 Protein Increases White Matter Resilience and Neurofunctional Recovery after Ischemic Stroke. International Journal of Molecular Sciences, 24(17), 13289. https://doi.org/10.3390/ijms241713289

Transient axonal glycoprotein-1 induces apoptosis-related gene expression without triggering apoptosis in U251 glioma cells

Neural Regeneration Research / Jan 01, 2014

Jin, B., Jiang, X., Chang, H., Song, S., Chen, Z., Wang, Y., Yang, L., Du, M., Ke, Y., & Xu, R. (2014). Transient axonal glycoprotein-1 induces apoptosis-related gene expression without triggering apoptosis in U251 glioma cells. Neural Regeneration Research, 9(5), 519. https://doi.org/10.4103/1673-5374.130079

Transient ischemic stroke triggers sustained damage of the choroid plexus blood-CSF barrier

Frontiers in Cellular Neuroscience / Dec 01, 2023

Chen, Y., Lin, L., Bhuiyan, M. I. H., He, K., Jha, R., Song, S., Fiesler, V. M., Begum, G., Yin, Y., & Sun, D. (2023). Transient ischemic stroke triggers sustained damage of the choroid plexus blood-CSF barrier. Frontiers in Cellular Neuroscience, 17. https://doi.org/10.3389/fncel.2023.1279385

Does Adjuvant Gamma Knife Stereotactic Radiosurgery Have a Role in Treating Optic Nerve Sheath Meningiomas?

Journal of Neuro-Ophthalmology / Jul 05, 2023

Wei, Z., Taori, S., Song, S., Deng, H., Niranjan, A., & Lunsford, L. D. (2023). Does Adjuvant Gamma Knife Stereotactic Radiosurgery Have a Role in Treating Optic Nerve Sheath Meningiomas? Journal of Neuro-Ophthalmology. https://doi.org/10.1097/wno.0000000000001914

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Boris Leibovitch

New York, New York, United States of America

Experienced wet lab and in teaching Molecular Cell biologist, geneticist, cancer biologist in Academia

Most Relevant Research Interests