Stan Karsten
Experienced R&D Investigator
Research Interests
Publications
Automated Capillary-Based Vacuum Pulse-Assisted Instrument for Single-Cell Acquisition and Concurrent Detachment/Adhesion Assay, A-picK
SLAS Technology / Oct 01, 2021
Ma, D., Ma, Z., Kudo, L. C., & Karsten, S. L. (2021). Automated Capillary-Based Vacuum Pulse-Assisted Instrument for Single-Cell Acquisition and Concurrent Detachment/Adhesion Assay, A-picK. SLAS Technology, 26(5), 519–531. https://doi.org/10.1177/2472630320987219
Nanopin - A MEMS Based Sensor for the Analysis of Single Cell Mechanical Properties
2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS) / Jan 01, 2020
Kumemura, M., Kudo, L. C., Ma, Z., & Karsten, S. L. (2020, January). Nanopin - A MEMS Based Sensor for the Analysis of Single Cell Mechanical Properties. 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS). https://doi.org/10.1109/mems46641.2020.9056113
Developing a MEMS Device with Built-in Microfluidics for Biophysical Single Cell Characterization
Micromachines / Jun 01, 2018
Takayama, Y., Perret, G., Kumemura, M., Ataka, M., Meignan, S., Karsten, S., Fujita, H., Collard, D., Lagadec, C., & Tarhan, M. (2018). Developing a MEMS Device with Built-in Microfluidics for Biophysical Single Cell Characterization. Micromachines, 9(6), 275. https://doi.org/10.3390/mi9060275
Microfluidic Tissue Mesodissection in Molecular Cancer Diagnostics
SLAS Technology / Aug 01, 2017
Surrette, C., Shoudy, D., Corwin, A., Gao, W., Zavodszky, M. I., Karsten, S. L., Miller, T., Gerdes, M. J., Wood, N., Nelson, J. R., & Puleo, C. M. (2017). Microfluidic Tissue Mesodissection in Molecular Cancer Diagnostics. SLAS Technology, 22(4), 425–430. https://doi.org/10.1177/2211068216680208
Microtubule density and landing rate as parameters to analyze tau protein in the MT-kinesin “gliding” assay
Sensors and Actuators B: Chemical / Jan 01, 2017
Subramaniyan Parimalam, S., Tarhan, M. C., Karsten, S. L., Fujita, H., Shintaku, H., Kotera, H., & Yokokawa, R. (2017). Microtubule density and landing rate as parameters to analyze tau protein in the MT-kinesin “gliding” assay. Sensors and Actuators B: Chemical, 238, 954–961. https://doi.org/10.1016/j.snb.2016.07.082
Direct electrical and mechanical characterization of in situ generated DNA between the tips of silicon nanotweezers (SNT)
Lab on a Chip / Jan 01, 2016
Karsten, S. L., Kumemura, M., Jalabert, L., Lafitte, N., Kudo, L. C., Collard, D., & Fujita, H. (2016). Direct electrical and mechanical characterization of in situ generated DNA between the tips of silicon nanotweezers (SNT). Lab on a Chip, 16(11), 2099–2107. https://doi.org/10.1039/c6lc00309e
Nano systems and devices for applications in biology and nanotechnology
Solid-State Electronics / Jan 01, 2016
Perret, G., Ginet, P., Tarhan, M. C., Baccouche, A., Lacornerie, T., Kumemura, M., Jalabert, L., Cleri, F., Lartigau, E. F., Kim, B. J., Karsten, S. L., Fujita, H., Rondelez, Y., Fujii, T., & Collard, D. (2016). Nano systems and devices for applications in biology and nanotechnology. Solid-State Electronics, 115, 66–73. https://doi.org/10.1016/j.sse.2015.08.019
On-chip microtubule gliding assay for parallel measurement of tau protein species
Lab on a Chip / Jan 01, 2016
Subramaniyan Parimalam, S., Tarhan, M. C., Karsten, S. L., Fujita, H., Shintaku, H., Kotera, H., & Yokokawa, R. (2016). On-chip microtubule gliding assay for parallel measurement of tau protein species. Lab on a Chip, 16(9), 1691–1697. https://doi.org/10.1039/c5lc01486g
On-chip detection of wild 3R, 4R and mutant 4R tau through kinesin-microtubule binding
2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) / Jan 01, 2015
Subramaniyan, S. P., Tarhan, M. C., Karsten, S. L., Fujita, H., Shintaku, H., Kotera, H., & Yokokawa, R. (2015, January). On-chip detection of wild 3R, 4R and mutant 4R tau through kinesin-microtubule binding. 2015 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS). https://doi.org/10.1109/memsys.2015.7050988
Point-of-care (POC) devices by means of advanced MEMS
Talanta / Dec 01, 2015
Karsten, S. L., Tarhan, M. C., Kudo, L. C., Collard, D., & Fujita, H. (2015). Point-of-care (POC) devices by means of advanced MEMS. Talanta, 145, 55–59. https://doi.org/10.1016/j.talanta.2015.04.032
Detection of mutations in the binding domain of tau protein by kinesin-microtubule gliding assay
2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS) / Jan 01, 2014
Subramaniyan, S. P., Tarhan, M. C., Karsten, S. L., Fujita, H., Shintaku, H., Kotera, H., & Yokokawa, R. (2014, January). Detection of mutations in the binding domain of tau protein by kinesin-microtubule gliding assay. 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS). https://doi.org/10.1109/memsys.2014.6765639
Intestinal tumor suppression in ApcMin/+ mice by prostaglandin
D2 receptor PTGDR
Cancer Medicine / Apr 12, 2014
Tippin, B. L., Kwong, A. M., Inadomi, M. J., Lee, O. J., Park, J. M., Materi, A. M., Buslon, V. S., Lin, A. M., Kudo, L. C., Karsten, S. L., French, S. W., Narumiya, S., Urade, Y., Salido, E., & Lin, H. J. (2014). Intestinal tumor suppression in ApcMin/+ mice by prostaglandin D2 receptor <scp>PTGDR</scp>. Cancer Medicine, 3(4), 1041–1051. Portico. https://doi.org/10.1002/cam4.251
Biosensing MAPs as “roadblocks”: kinesin-based functional analysis of tau protein isoforms and mutants using suspended microtubules (sMTs)
Lab on a Chip / Jan 01, 2013
Tarhan, M. C., Orazov, Y., Yokokawa, R., Karsten, S. L., & Fujita, H. (2013). Biosensing MAPs as “roadblocks”: kinesin-based functional analysis of tau protein isoforms and mutants using suspended microtubules (sMTs). Lab on a Chip, 13(16), 3217. https://doi.org/10.1039/c3lc50151e
Motor protein based tau protein detection device
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII) / Jun 01, 2013
Orazov, Y., Tarhan, M. C., Yokokawa, R., Karsten, S. L., & Fujita, H. (2013, June). Motor protein based tau protein detection device. 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII). https://doi.org/10.1109/transducers.2013.6627301
Nano bioresearch approach by microtechnology
Drug Discovery Today / Jun 01, 2013
Collard, D., Kim, S. H., Osaki, T., Kumemura, M., Kim, B., Fourmy, D., Fujii, T., Takeuchi, S., Karsten, S. L., & Fujita, H. (2013). Nano bioresearch approach by microtechnology. Drug Discovery Today, 18(11–12), 552–559. https://doi.org/10.1016/j.drudis.2013.02.002
Suspended microtubules demonstrate high sensitivity and low experimental variability in kinesin bead assay
The Analyst / Jan 01, 2013
Tarhan, M. C., Orazov, Y., Yokokawa, R., Karsten, S. L., & Fujita, H. (2013). Suspended microtubules demonstrate high sensitivity and low experimental variability in kinesin bead assay. The Analyst, 138(6), 1653. https://doi.org/10.1039/c3an36545j
Puromycin-sensitive aminopeptidase is involved in wild-type huntingtin clearance
Molecular Neurodegeneration / Feb 07, 2012
Ren, G., Ma, Z., Hui, M., Kudo, L. C., Hui, K.-S., & Karsten, S. L. (2012). Puromycin-sensitive aminopeptidase is involved in wild-type huntingtin clearance. Molecular Neurodegeneration, 7(S1). https://doi.org/10.1186/1750-1326-7-s1-s5
Education
Uppsala University
PhD, Genetics and Pathology
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