Felipe Oyarzun-Ampuero
Professor at Universidad of Chile with wide interest in encapsulation at nano, micro and macroscale
Research Interests
About
Publications
Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma
International Journal of Pharmaceutics / Nov 01, 2009
Oyarzun-Ampuero, F. A., Brea, J., Loza, M. I., Torres, D., & Alonso, M. J. (2009). Chitosan–hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma. International Journal of Pharmaceutics, 381(2), 122–129. https://doi.org/10.1016/j.ijpharm.2009.04.009
Conventional spray-drying and future trends for the microencapsulation of fish oil
Trends in Food Science & Technology / Oct 01, 2016
Encina, C., Vergara, C., Giménez, B., Oyarzún-Ampuero, F., & Robert, P. (2016). Conventional spray-drying and future trends for the microencapsulation of fish oil. Trends in Food Science & Technology, 56, 46–60. https://doi.org/10.1016/j.tifs.2016.07.014
Nanoparticles for the Treatment of Wounds
Current Pharmaceutical Design / Oct 07, 2015
Oyarzun-Ampuero, F., Vidal, A., Concha, M., Morales, J., Orellana, S., & Moreno-Villoslada, I. (2015). Nanoparticles for the Treatment of Wounds. Current Pharmaceutical Design, 21(29), 4329–4341. https://doi.org/10.2174/1381612821666150901104601
Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery
European Journal of Pharmaceutical Sciences / Jul 01, 2013
Oyarzun-Ampuero, F. A., Rivera-Rodríguez, G. R., Alonso, M. J., & Torres, D. (2013). Hyaluronan nanocapsules as a new vehicle for intracellular drug delivery. European Journal of Pharmaceutical Sciences, 49(4), 483–490. https://doi.org/10.1016/j.ejps.2013.05.008
Polymeric Nanoparticles for Increasing Oral Bioavailability of Curcumin
Antioxidants / Mar 24, 2018
Umerska, A., Gaucher, C., Oyarzun-Ampuero, F., Fries-Raeth, I., Colin, F., Villamizar-Sarmiento, M., Maincent, P., & Sapin-Minet, A. (2018). Polymeric Nanoparticles for Increasing Oral Bioavailability of Curcumin. Antioxidants, 7(4), 46. https://doi.org/10.3390/antiox7040046
Curcumin-loaded nanoemulsion: a new safe and effective formulation to prevent tumor reincidence and metastasis
Nanoscale / Jan 01, 2018
Guerrero, S., Inostroza-Riquelme, M., Contreras-Orellana, P., Diaz-Garcia, V., Lara, P., Vivanco-Palma, A., Cárdenas, A., Miranda, V., Robert, P., Leyton, L., Kogan, M. J., Quest, A. F. G., & Oyarzun-Ampuero, F. (2018). Curcumin-loaded nanoemulsion: a new safe and effective formulation to prevent tumor reincidence and metastasis. Nanoscale, 10(47), 22612–22622. https://doi.org/10.1039/c8nr06173d
A new drug nanocarrier consisting of polyarginine and hyaluronic acid
European Journal of Pharmaceutics and Biopharmaceutics / Sep 01, 2011
Oyarzun-Ampuero, F. A., Goycoolea, F. M., Torres, D., & Alonso, M. J. (2011). A new drug nanocarrier consisting of polyarginine and hyaluronic acid. European Journal of Pharmaceutics and Biopharmaceutics, 79(1), 54–57. https://doi.org/10.1016/j.ejpb.2011.04.008
Lipid nanoparticles for the topical delivery of retinoids and derivatives
Nanomedicine / Jan 01, 2015
Morales, J. O., Valdés, K., Morales, J., & Oyarzun-Ampuero, F. (2015). Lipid nanoparticles for the topical delivery of retinoids and derivatives. Nanomedicine, 10(2), 253–269. https://doi.org/10.2217/nnm.14.159
Double emulsions as potential fat replacers with gallic acid and quercetin nanoemulsions in the aqueous phases
Food Chemistry / Jul 01, 2018
Silva, W., Torres-Gatica, M. F., Oyarzun-Ampuero, F., Silva-Weiss, A., Robert, P., Cofrades, S., & Giménez, B. (2018). Double emulsions as potential fat replacers with gallic acid and quercetin nanoemulsions in the aqueous phases. Food Chemistry, 253, 71–78. https://doi.org/10.1016/j.foodchem.2018.01.128
Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy
Journal of Controlled Release / Mar 01, 2021
González, L. F., Acuña, E., Arellano, G., Morales, P., Sotomayor, P., Oyarzun-Ampuero, F., & Naves, R. (2021). Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 331, 443–459. https://doi.org/10.1016/j.jconrel.2020.11.019
Design, development and evaluation of nanoemulsion containing avocado peel extract with anticancer potential: A novel biological active ingredient to enrich food
Food Hydrocolloids / Feb 01, 2021
Cerda-Opazo, P., Gotteland, M., Oyarzun-Ampuero, F. A., & Garcia, L. (2021). Design, development and evaluation of nanoemulsion containing avocado peel extract with anticancer potential: A novel biological active ingredient to enrich food. Food Hydrocolloids, 111, 106370. https://doi.org/10.1016/j.foodhyd.2020.106370
A Simple Mathematical Model for Wound Closure Evaluation
Journal of the American College of Clinical Wound Specialists / Dec 01, 2015
Vidal, A., Mendieta Zerón, H., Giacaman, I., Camarillo Romero, M. del S., López, S. P., Meza Trillo, L. E., Pérez Pérez, D. A., Concha, M., Torres-Gallegos, C., Orellana, S. L., Oyarzun-Ampuero, F., & Moreno-Villoslada, I. (2015). A Simple Mathematical Model for Wound Closure Evaluation. Journal of the American College of Clinical Wound Specialists, 7(1–3), 40–49. https://doi.org/10.1016/j.jccw.2016.07.002
Nanocapsules as Carriers for the Transport and Targeted Delivery of Bioactive Molecules
Nanocomposite Particles for Bio-Applications / Jul 18, 2011
Hervella, P., Lollo, G., Oyarzun-Ampuero, F., Rivera, G., Torres, D., & Alonso, M. (2011). Nanocapsules as Carriers for the Transport and Targeted Delivery of Bioactive Molecules. In Nanocomposite Particles for Bio-Applications (pp. 45–67). Pan Stanford Publishing. https://doi.org/10.1201/b11035-4
Surface-Modified Nanoparticles to Improve Drug Delivery
Dekker Encyclopedia of Nanoscience and Nanotechnology, Third Edition / Oct 21, 2014
Oyarzun-Ampuero, F., Kogan, M. J., Neira-Carrillo, A., & Morales, J. O. (2014). Surface-Modified Nanoparticles to Improve Drug Delivery. In Dekker Encyclopedia of Nanoscience and Nanotechnology, Third Edition (pp. 1–7). Taylor & Francis. https://doi.org/10.1081/e-enn3-120051984
Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose: An in vitro release study
LWT / Jan 01, 2024
Lopez-Polo, J., Soto, A., Zamorano, M., Silva-Weiss, A., Oyarzun-Ampuero, F. A., Brossard, N., Fuentes, J., & Osorio, F. A. (2024). Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose: An in vitro release study. LWT, 191, 115583. https://doi.org/10.1016/j.lwt.2023.115583
Correction to: Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
Diabetology & Metabolic Syndrome / Aug 19, 2020
Jara, C., Oyarzun-Ampuero, F., Carrión, F., González-Echeverría, E., Cappelli, C., & Caviedes, P. (2020). Correction to: Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue. Diabetology & Metabolic Syndrome, 12(1). https://doi.org/10.1186/s13098-020-00581-9
Colloidal nanomedicines with prolonged release of chloroquine based on interactions with aromatic polymers after mixing two liquids: from in silico simulation of nanoparticle formation to efficient in-bench scale up
Journal of Molecular Liquids / Feb 01, 2024
Gabriela Villamizar-Sarmiento, M., Yáñez, O., Flores, M. E., Álvarez-Acevedo, G., González-Nilo, F., Guerrero, J., Moreno-Villoslada, I., & Oyarzun-Ampuero, F. A. (2024). Colloidal nanomedicines with prolonged release of chloroquine based on interactions with aromatic polymers after mixing two liquids: from in silico simulation of nanoparticle formation to efficient in-bench scale up. Journal of Molecular Liquids, 395, 123906. https://doi.org/10.1016/j.molliq.2023.123906
Thermosensitive Chitosan Hydrogels: A Potential Strategy for Prolonged Iron Dextran Parenteral Supplementation
Polymers / Dec 31, 2023
Durán, E., Neira-Carrillo, A., Oyarzun-Ampuero, F., & Valenzuela, C. (2023). Thermosensitive Chitosan Hydrogels: A Potential Strategy for Prolonged Iron Dextran Parenteral Supplementation. Polymers, 16(1), 139. https://doi.org/10.3390/polym16010139
Thermosensitive Chitosan Hydrogels as a Vehicle for Iron Dextran as a Potential Strategy for Parenteral Nutrient Supplementation
Nov 08, 2023
Durán, E., Neira-Carrillo, A., Oyarzun-Ampuero, F., & Valenzuela, C. (2023). Thermosensitive Chitosan Hydrogels as a Vehicle for Iron Dextran as a Potential Strategy for Parenteral Nutrient Supplementation. https://doi.org/10.20944/preprints202311.0528.v1
The Critical Role of Aromatic-Aromatic Drug-Polymer Interactions to Provide Nanomedicines Containing Chloroquine: A Simple Proposal to Provide High Encapsulation, High Stability, and Prolonged Drug Release
Nov 12, 2020
Villamizar-Sarmiento, M. G., Moreno-Villoslada, I., & Oyarzun-Ampuero, F. (2020). The Critical Role of Aromatic-Aromatic Drug-Polymer Interactions to Provide Nanomedicines Containing Chloroquine: A Simple Proposal to Provide High Encapsulation, High Stability, and Prolonged Drug Release. https://doi.org/10.21203/rs.3.rs-101145/v1
Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue.
Jul 15, 2020
Jara, C., Oyarzun-Ampuero, F., Carrión, F., González-Echeverría, E., Cappelli, C., & Caviedes, P. (2020). Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue. https://doi.org/10.21203/rs.3.rs-22053/v2
The Anti-Oxidant Curcumin Solubilized as Oil-in-Water Nanoemulsions or Chitosan Nanocapsules Effectively Reduces Helicobacter pylori Growth, Bacterial Biofilm Formation, Gastric Cell Adhesion and Internalization
Antioxidants / Oct 16, 2023
Hidalgo, A., Bravo, D., Soto, C., Maturana, G., Cordero-Machuca, J., Zúñiga-López, M. C., Oyarzun-Ampuero, F., & Quest, A. F. G. (2023). The Anti-Oxidant Curcumin Solubilized as Oil-in-Water Nanoemulsions or Chitosan Nanocapsules Effectively Reduces Helicobacter pylori Growth, Bacterial Biofilm Formation, Gastric Cell Adhesion and Internalization. Antioxidants, 12(10), 1866. https://doi.org/10.3390/antiox12101866
Development of biodegradable and vermicompostable films based on alginate and waste eggshells
Food Hydrocolloids / Sep 01, 2023
Villanueva, V., Valdés, F., Zúñiga, R. N., Villamizar-Sarmiento, M. G., Soto-Bustamante, E., Romero-Hasler, P., Riveros, A. L., Tapia, J., Lisoni, J., Oyarzun-Ampuero, F., & Valenzuela, C. (2023). Development of biodegradable and vermicompostable films based on alginate and waste eggshells. Food Hydrocolloids, 142, 108813. https://doi.org/10.1016/j.foodhyd.2023.108813
Efficacy of stem cell secretome loaded in hyaluronate sponge for topical treatment of psoriasis
Bioengineering & Translational Medicine / Feb 21, 2023
Carrillo, D., Edwards, N., Arancibia‐Altamirano, D., Otárola, F., Villarroel, C., Prieto, C. P., Villamizar‐Sarmiento, M. G., Sauma, D., Valenzuela, F., Lattus, J., Oyarzun‐Ampuero, F., & Palma, V. (2023). Efficacy of stem cell secretome loaded in hyaluronate sponge for topical treatment of psoriasis. Bioengineering & Translational Medicine, 8(2). Portico. https://doi.org/10.1002/btm2.10443
Encapsulation of house fly larvae (Musca domestica) meal by ionic gelation as a strategy to develop a novel nutritive food ingredient with improved aroma and appearance
LWT / Jun 01, 2022
Sánchez, M., Villamizar-Sarmiento, M. G., Harmsen, I., Valdés, F., Villanueva, V., Ceballos, R., Wacyk, J., Oyarzun-Ampuero, F., & Valenzuela, C. (2022). Encapsulation of house fly larvae (Musca domestica) meal by ionic gelation as a strategy to develop a novel nutritive food ingredient with improved aroma and appearance. LWT, 163, 113597. https://doi.org/10.1016/j.lwt.2022.113597
Influence of the particle size of encapsulated chia oil on the oil release and bioaccessibility during in vitro gastrointestinal digestion
Food & Function / Jan 01, 2022
Álvarez, R., Giménez, B., Mackie, A., Torcello-Gómez, A., Quintriqueo, A., Oyarzun-Ampuero, F., & Robert, P. (2022). Influence of the particle size of encapsulated chia oil on the oil release and bioaccessibility during in vitro gastrointestinal digestion. Food & Function, 13(3), 1370–1379. https://doi.org/10.1039/d1fo03688b
MWCNT‐Organoimido Polyoxomolybdate Hybrid Material: Analytical Applications for Amperometric Sensing of Hydrogen Peroxide
Electroanalysis / May 26, 2021
Mujica, M. L., Sotomayor‐Santander, I., Hermosilla‐Ibáñez, P., Oyarzun‐Ampuero, F., Rodríguez, M. C., Rivas, G. A., Venegas‐Yazigi, D., & Bollo, S. (2021). MWCNT‐Organoimido Polyoxomolybdate Hybrid Material: Analytical Applications for Amperometric Sensing of Hydrogen Peroxide. Electroanalysis, 33(9), 2105–2114. Portico. https://doi.org/10.1002/elan.202100149
The key role of the drug self-aggregation ability to obtain optimal nanocarriers based on aromatic-aromatic drug-polymer interactions
European Journal of Pharmaceutics and Biopharmaceutics / Sep 01, 2021
Villamizar-Sarmiento, M. G., Guerrero, J., Moreno-Villoslada, I., & Oyarzun-Ampuero, F. A. (2021). The key role of the drug self-aggregation ability to obtain optimal nanocarriers based on aromatic-aromatic drug-polymer interactions. European Journal of Pharmaceutics and Biopharmaceutics, 166, 19–29. https://doi.org/10.1016/j.ejpb.2021.05.023
A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo
International Journal of Molecular Sciences / Aug 04, 2021
Zárate, A. M., Espinosa-Bustos, C., Guerrero, S., Fierro, A., Oyarzún-Ampuero, F., Quest, A. F. G., Di Marcotullio, L., Loricchio, E., Caimano, M., Calcaterra, A., González-Quiroz, M., Aguirre, A., Meléndez, J., & Salas, C. O. (2021). A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo. International Journal of Molecular Sciences, 22(16), 8372. https://doi.org/10.3390/ijms22168372
House fly (Musca domestica) larvae meal as an ingredient with high nutritional value: Microencapsulation and improvement of organoleptic characteristics
Food Research International / Jul 01, 2021
Sánchez, M., Gómez, C., Avendaño, C., Harmsen, I., Ortiz, D., Ceballos, R., Villamizar-Sarmiento, M. G., Oyarzun-Ampuero, F., Wacyk, J., & Valenzuela, C. (2021). House fly (Musca domestica) larvae meal as an ingredient with high nutritional value: Microencapsulation and improvement of organoleptic characteristics. Food Research International, 145, 110423. https://doi.org/10.1016/j.foodres.2021.110423
Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
Diabetology & Metabolic Syndrome / Aug 05, 2020
Jara, C., Oyarzun-Ampuero, F., Carrión, F., González-Echeverría, E., Cappelli, C., & Caviedes, P. (2020). Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue. Diabetology & Metabolic Syndrome, 12(1). https://doi.org/10.1186/s13098-020-00573-9
Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation
Marine Drugs / Jun 26, 2020
García, F., Lobos, P., Ponce, A., Cataldo, K., Meza, D., Farías, P., Estay, C., Oyarzun-Ampuero, F., Herrera-Molina, R., Paula-Lima, A., Ardiles, Á. O., Hidalgo, C., Adasme, T., & Muñoz, P. (2020). Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation. Marine Drugs, 18(6), 335. https://doi.org/10.3390/md18060335
Encapsulation of Iron Oxide Nanoparticles and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential
Journal of Nanoscience and Nanotechnology / Aug 01, 2019
Álvarez-Acevedo, G., Inostroza-Riquelme, M., Chornik, B., Flores, M., & Oyarzun-Ampuero, F. (2019). Encapsulation of Iron Oxide Nanoparticles and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential. Journal of Nanoscience and Nanotechnology, 19(8), 4938–4945. https://doi.org/10.1166/jnn.2019.16789
A New Methodology to Create Polymeric Nanocarriers Containing Hydrophilic Low Molecular-Weight Drugs: A Green Strategy Providing a Very High Drug Loading
Molecular Pharmaceutics / Jun 03, 2019
Villamizar-Sarmiento, M. G., Molina-Soto, E. F., Guerrero, J., Shibue, T., Nishide, H., Moreno-Villoslada, I., & Oyarzun-Ampuero, F. A. (2019). A New Methodology to Create Polymeric Nanocarriers Containing Hydrophilic Low Molecular-Weight Drugs: A Green Strategy Providing a Very High Drug Loading. Molecular Pharmaceutics, 16(7), 2892–2901. https://doi.org/10.1021/acs.molpharmaceut.9b00097
Ionic Nanocomplexes of Hyaluronic Acid and Polyarginine to Form Solid Materials: A Green Methodology to Obtain Sponges with Biomedical Potential
Nanomaterials / Jun 29, 2019
Villamizar-Sarmiento, M. G., Moreno-Villoslada, I., Martínez, S., Giacaman, A., Miranda, V., Vidal, A., Orellana, S. L., Concha, M., Pavicic, F., Lisoni, J. G., Leyton, L., & Oyarzun-Ampuero, F. A. (2019). Ionic Nanocomplexes of Hyaluronic Acid and Polyarginine to Form Solid Materials: A Green Methodology to Obtain Sponges with Biomedical Potential. Nanomaterials, 9(7), 944. https://doi.org/10.3390/nano9070944
Synthesis of tuneable amphiphilic-modified polyketone polymers, their complexes with 5,10,15,20-tetrakis-(4-sulfonatophenyl)porphyrin, and their role in the photooxidation of 1,3,5-triphenylformazan confined in polymeric nanoparticles
Polymer / Mar 01, 2019
Araya-Hermosilla, E., Roscam Abbing, M., Catalán-Toledo, J., Oyarzun-Ampuero, F., Pucci, A., Raffa, P., Picchioni, F., & Moreno-Villoslada, I. (2019). Synthesis of tuneable amphiphilic-modified polyketone polymers, their complexes with 5,10,15,20-tetrakis-(4-sulfonatophenyl)porphyrin, and their role in the photooxidation of 1,3,5-triphenylformazan confined in polymeric nanoparticles. Polymer, 167, 215–223. https://doi.org/10.1016/j.polymer.2019.01.079
A simple and green methodology to assemble poly(4-vinylpyridine) and a sulfonated azo-dye for obtaining stable polymeric nanoparticles
Polymer / Dec 01, 2018
Catalán-Toledo, J., Nenen, A., Vallejos, G. A., Oyarzun-Ampuero, F., Shibue, T., Nishide, H., & Moreno-Villoslada, I. (2018). A simple and green methodology to assemble poly(4-vinylpyridine) and a sulfonated azo-dye for obtaining stable polymeric nanoparticles. Polymer, 158, 289–296. https://doi.org/10.1016/j.polymer.2018.09.062
Dermal Collagen Stabilization by Polyphenols and Spray Drying as an Encapsulation Strategy
Current Topics in Medicinal Chemistry / Oct 10, 2018
Anazco, C., Rojas, A., Gonzalez, I., Castro, M. A., Robert, P., & Oyarzun-Ampuero, F. (2018). Dermal Collagen Stabilization by Polyphenols and Spray Drying as an Encapsulation Strategy. Current Topics in Medicinal Chemistry, 18(14), 1242–1251. https://doi.org/10.2174/1568026618666180810143730
Protection of astaxanthin from photodegradation by its inclusion in hierarchically assembled nano and microstructures with potential as food
Food Hydrocolloids / Oct 01, 2018
Alarcón-Alarcón, C., Inostroza-Riquelme, M., Torres-Gallegos, C., Araya, C., Miranda, M., Sánchez-Caamaño, J. C., Moreno-Villoslada, I., & Oyarzun-Ampuero, F. A. (2018). Protection of astaxanthin from photodegradation by its inclusion in hierarchically assembled nano and microstructures with potential as food. Food Hydrocolloids, 83, 36–44. https://doi.org/10.1016/j.foodhyd.2018.04.033
Aerogels made of chitosan and chondroitin sulfate at high degree of neutralization: Biological properties toward wound healing
Journal of Biomedical Materials Research Part B: Applied Biomaterials / Feb 09, 2018
Concha, M., Vidal, A., Giacaman, A., Ojeda, J., Pavicic, F., Oyarzun‐Ampuero, F. A., Torres, C., Cabrera, M., Moreno‐Villoslada, I., & Orellana, S. L. (2018). Aerogels made of chitosan and chondroitin sulfate at high degree of neutralization: Biological properties toward wound healing. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 106(6), 2464–2471. Portico. https://doi.org/10.1002/jbm.b.34038
Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential
Molecules / May 18, 2018
Inostroza-Riquelme, M., Vivanco, A., Lara, P., Guerrero, S., Salas-Huenuleo, E., Chamorro, A., Leyton, L., Bolaños, K., Araya, E., Quest, A., Kogan, M., & Oyarzun-Ampuero, F. (2018). Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential. Molecules, 23(5), 1208. https://doi.org/10.3390/molecules23051208
Antibacterial activity against Staphylococcus aureus of chitosan/chondroitin sulfate nanocomplex aerogels alone and enriched with erythromycin and elephant garlic (Allium ampeloprasum L. var. ampeloprasum) extract
Pure and Applied Chemistry / Jan 17, 2018
Gómez, M. A., Bonilla, J. M., Coronel, M. A., Martínez, J., Morán-Trujillo, L., Orellana, S. L., Vidal, A., Giacaman, A., Morales, C., Torres-Gallegos, C., Concha, M., Oyarzun-Ampuero, F., Godoy, P., Lisoni, J. G., Henríquez-Báez, C., Bustos, C., & Moreno-Villoslada, I. (2018). Antibacterial activity against Staphylococcus aureus of chitosan/chondroitin sulfate nanocomplex aerogels alone and enriched with erythromycin and elephant garlic (Allium ampeloprasum L. var. ampeloprasum) extract. Pure and Applied Chemistry, 90(5), 885–900. https://doi.org/10.1515/pac-2016-1112
Chitosan/chondroitin sulfate aerogels with high polymeric electroneutralization degree: formation and mechanical properties
Pure and Applied Chemistry / Dec 21, 2017
Orellana, S. L., Giacaman, A., Vidal, A., Morales, C., Oyarzun-Ampuero, F., Lisoni, J. G., Henríquez-Báez, C., Morán-Trujillo, L., Concha, M., & Moreno-Villoslada, I. (2017). Chitosan/chondroitin sulfate aerogels with high polymeric electroneutralization degree: formation and mechanical properties. Pure and Applied Chemistry, 90(5), 901–911. https://doi.org/10.1515/pac-2016-1111
Totally Organic Redox-Active pH-Sensitive Nanoparticles Stabilized by Amphiphilic Aromatic Polyketones
The Journal of Physical Chemistry B / Jan 29, 2018
Araya-Hermosilla, E., Catalán-Toledo, J., Muñoz-Suescun, F., Oyarzun-Ampuero, F., Raffa, P., Polgar, L. M., Picchioni, F., & Moreno-Villoslada, I. (2018). Totally Organic Redox-Active pH-Sensitive Nanoparticles Stabilized by Amphiphilic Aromatic Polyketones. The Journal of Physical Chemistry B, 122(5), 1747–1755. https://doi.org/10.1021/acs.jpcb.7b11254
Aerogels containing 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin with controlled state of aggregation
Dyes and Pigments / Apr 01, 2017
Pino-Pinto, J. P., Oyarzun-Ampuero, F., Orellana, S. L., Flores, M. E., Nishide, H., & Moreno-Villoslada, I. (2017). Aerogels containing 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin with controlled state of aggregation. Dyes and Pigments, 139, 193–200. https://doi.org/10.1016/j.dyepig.2016.12.005
Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy
Current Pharmaceutical Design / Dec 14, 2016
Guerrero, A., Oyarzun-Ampuero, F., Hassan, N., Corvalán, A., Quest, A., Kogan, M., & Kogan, M. (2016). Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy. Current Pharmaceutical Design, 22(39), 5988–5997. https://doi.org/10.2174/1381612822666160712165409
Facile Formation of Redox‐Active Totally Organic Nanoparticles in Water by In Situ Reduction of Organic Precursors Stabilized through Aromatic–Aromatic Interactions by Aromatic Polyelectrolytes
Macromolecular Rapid Communications / Sep 12, 2016
Flores, M. E., Garcés‐Jerez, P., Fernández, D., Aros‐Perez, G., González‐Cabrera, D., Álvarez, E., Cañas, I., Oyarzun‐Ampuero, F., & Moreno‐Villoslada, I. (2016). Facile Formation of Redox‐Active Totally Organic Nanoparticles in Water by In Situ Reduction of Organic Precursors Stabilized through Aromatic–Aromatic Interactions by Aromatic Polyelectrolytes. Macromolecular Rapid Communications, 37(21), 1729–1734. Portico. https://doi.org/10.1002/marc.201600339
Photochromic Solid Materials Based on Poly(decylviologen) Complexed with Alginate and Poly(sodium 4-styrenesulfonate)
The Journal of Physical Chemistry B / Oct 06, 2015
Sanhueza, L., Castro, J., Urzúa, E., Barrientos, L., Oyarzun-Ampuero, F., Pesenti, H., Shibue, T., Sugimura, N., Tomita, W., Nishide, H., & Moreno-Villoslada, I. (2015). Photochromic Solid Materials Based on Poly(decylviologen) Complexed with Alginate and Poly(sodium 4-styrenesulfonate). The Journal of Physical Chemistry B, 119(41), 13208–13217. https://doi.org/10.1021/acs.jpcb.5b05963
Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases
Current Pharmaceutical Design / Oct 07, 2015
Morales, J., Sepulveda-Rivas, S., Oyarzun-Ampuero, F., Lavandero, S., & Kogan, M. (2015). Novel Nanostructured Polymeric Carriers to Enable Drug Delivery for Cardiovascular Diseases. Current Pharmaceutical Design, 21(29), 4276–4284. https://doi.org/10.2174/1381612821666150901103556
Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer
Current Pharmaceutical Design / Oct 07, 2015
Oyarzun-Ampuero, F., Guerrero, A., Hassan-Lopez, N., Morales, J., Bollo, S., Corvalan, A., Quest, A., & Kogan, M. (2015). Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer. Current Pharmaceutical Design, 21(29), 4145–4154. https://doi.org/10.2174/1381612821666150901095538
Association Efficiency of Three Ionic Forms of Oxytetracycline to Cationic and Anionic Oil-In-Water Nanoemulsions Analyzed by Diafiltration
Journal of Pharmaceutical Sciences / Mar 01, 2015
Orellana, S. L., Torres-Gallegos, C., Araya-Hermosilla, R., Oyarzun-Ampuero, F., & Moreno-Villoslada, I. (2015). Association Efficiency of Three Ionic Forms of Oxytetracycline to Cationic and Anionic Oil-In-Water Nanoemulsions Analyzed by Diafiltration. Journal of Pharmaceutical Sciences, 104(3), 1141–1152. https://doi.org/10.1002/jps.24255
Immobilization of rhodamine 6G in calcium alginate microcapsules based on aromatic–aromatic interactions with poly(sodium 4-styrenesulfonate)
Reactive and Functional Polymers / Aug 01, 2014
Araya-Hermosilla, E., Muñoz, D., Orellana, S., Yáñez, A., Olea, A. F., Oyarzun-Ampuero, F., & Moreno-Villoslada, I. (2014). Immobilization of rhodamine 6G in calcium alginate microcapsules based on aromatic–aromatic interactions with poly(sodium 4-styrenesulfonate). Reactive and Functional Polymers, 81, 14–21. https://doi.org/10.1016/j.reactfunctpolym.2014.03.017
Flow Chemistry to Control the Synthesis of Nano and Microparticles for Biomedical Applications
Current Topics in Medicinal Chemistry / Feb 01, 2014
Hassan, N., Oyarzun-Ampuero, F., Lara, P., Guerrero, S., Cabuil, V., Abou-Hassan, A., & Kogan, M. (2014). Flow Chemistry to Control the Synthesis of Nano and Microparticles for Biomedical Applications. Current Topics in Medicinal Chemistry, 14(5), 676–689. https://doi.org/10.2174/1568026614666140118213915
Therapeutic Potential of a Low-Cost Device for Wound Healing
American Journal of Therapeutics / Jul 01, 2013
Vidal, A., Giacaman, A., Oyarzun-Ampuero, F. A., Orellana, S., Aburto, I., Pavicic, M. F., Sánchez, A., López, C., Morales, C., Caro, M., Moreno-Villoslada, I., & Concha, M. (2013). Therapeutic Potential of a Low-Cost Device for Wound Healing: A Study of Three Cases of Healing After Lower-Extremity Amputation in Patients With Diabetes. American Journal of Therapeutics, 20(4), 394–398. https://doi.org/10.1097/mjt.0b013e318235f309
A Potential Nanomedicine Consisting of Heparin‐Loaded Polysaccharide Nanocarriers for the Treatment of Asthma
Macromolecular Bioscience / Nov 23, 2011
Oyarzun‐Ampuero, F. A., Brea, J., Loza, M. I., Alonso, M. J., & Torres, D. (2011). A Potential Nanomedicine Consisting of Heparin‐Loaded Polysaccharide Nanocarriers for the Treatment of Asthma. Macromolecular Bioscience, 12(2), 176–183. Portico. https://doi.org/10.1002/mabi.201100102
Chitosan-coated lipid nanocarriers for therapeutic applications
Journal of Drug Delivery Science and Technology / Jan 01, 2010
Oyarzun-Ampuero, F. A., Garcia-Fuentes, M., Torres, D., & Alonso, M. J. (2010). Chitosan-coated lipid nanocarriers for therapeutic applications. Journal of Drug Delivery Science and Technology, 20(4), 259–265. https://doi.org/10.1016/s1773-2247(10)50043-1
Binding of chlorpheniramine maleate to pharmacologically important alginic acid, carboxymethylcellulose, κ‐carageenan, and ι‐carrageenan as studied by diafiltration
Journal of Applied Polymer Science / Jul 26, 2005
Moreno‐Villoslada, I., Oyarzún, F., Miranda, V., Hess, S., & Rivas, B. L. (2005). Binding of chlorpheniramine maleate to pharmacologically important alginic acid, carboxymethylcellulose, κ‐carageenan, and ι‐carrageenan as studied by diafiltration. Journal of Applied Polymer Science, 98(2), 598–602. Portico. https://doi.org/10.1002/app.22056
Comparison between the binding of chlorpheniramine maleate to poly(sodium 4-styrenesulfonate) and the binding to other polyelectrolytes
Polymer / Aug 01, 2005
Moreno-Villoslada, I., Oyarzún, F., Miranda, V., Hess, S., & Rivas, B. L. (2005). Comparison between the binding of chlorpheniramine maleate to poly(sodium 4-styrenesulfonate) and the binding to other polyelectrolytes. Polymer, 46(18), 7240–7245. https://doi.org/10.1016/j.polymer.2005.06.033
USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS
Journal of the Chilean Chemical Society / Jun 01, 2004
Moreno-Villoslada, I., Miranda, V., Oyarzún, F., Hess, S., Luna, M., & Rivas, B. L. (2004). USE OF ULTRAFILTRATION ON THE EVALUATION AND QUANTIFICATION OF THE INTERACTIONS BETWEEN POLYMERS AND LOW MOLECULAR-WEIGHT MOLECULES IN AQUEOUS SOLUTIONS. Journal of the Chilean Chemical Society, 49(2). https://doi.org/10.4067/s0717-97072004000200003
Education
Austral University of Chile
Postdoc, Faculty of Medicine / January, 2013
University of Santiago de Compostela
Ph.D., Department of Pharmacy / November, 2011
Austral University of Chile
Pharmacist, Department of Pharmacy / March, 2004
Experience
University of Chile
Director / January, 2021 — Present
Associate Professor / January, 2016 — Present
Assistant Professor / January, 2013 — January, 2016
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