Khoa Nguyen
Life Sciences Expert with 18-Year Experience in Immunology, Metabolism, Neuroscience, and Biotech Entrepreuneuship
Research Interests
About
Publications
Macrophage-mediated inflammation in metabolic disease
Nature Reviews Immunology / Oct 10, 2011
Chawla, A., Nguyen, K. D., & Goh, Y. P. S. (2011). Macrophage-mediated inflammation in metabolic disease. Nature Reviews Immunology, 11(11), 738–749. https://doi.org/10.1038/nri3071
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Nature Methods / May 25, 2015
Paşca, A. M., Sloan, S. A., Clarke, L. E., Tian, Y., Makinson, C. D., Huber, N., Kim, C. H., Park, J.-Y., O’Rourke, N. A., Nguyen, K. D., Smith, S. J., Huguenard, J. R., Geschwind, D. H., Barres, B. A., & Paşca, S. P. (2015). Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nature Methods, 12(7), 671–678. https://doi.org/10.1038/nmeth.3415
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
Nature / Nov 20, 2011
Nguyen, K. D., Qiu, Y., Cui, X., Goh, Y. P. S., Mwangi, J., David, T., Mukundan, L., Brombacher, F., Locksley, R. M., & Chawla, A. (2011). Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature, 480(7375), 104–108. https://doi.org/10.1038/nature10653
Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat
Cell / Jun 01, 2014
Qiu, Y., Nguyen, K. D., Odegaard, J. I., Cui, X., Tian, X., Locksley, R. M., Palmiter, R. D., & Chawla, A. (2014). Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat. Cell, 157(6), 1292–1308. https://doi.org/10.1016/j.cell.2014.03.066
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
Nature Immunology / Mar 30, 2014
Mauer, J., Chaurasia, B., Goldau, J., Vogt, M. C., Ruud, J., Nguyen, K. D., Theurich, S., Hausen, A. C., Schmitz, J., Brönneke, H. S., Estevez, E., Allen, T. L., Mesaros, A., Partridge, L., Febbraio, M. A., Chawla, A., Wunderlich, F. T., & Brüning, J. C. (2014). Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology, 15(5), 423–430. https://doi.org/10.1038/ni.2865
Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6C hi Inflammatory Monocytes
Science / Sep 27, 2013
Nguyen, K. D., Fentress, S. J., Qiu, Y., Yun, K., Cox, J. S., & Chawla, A. (2013). Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6C hi Inflammatory Monocytes. Science, 341(6153), 1483–1488. https://doi.org/10.1126/science.1240636
Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing
Science Translational Medicine / Dec 23, 2009
Boyd, S. D., Marshall, E. L., Merker, J. D., Maniar, J. M., Zhang, L. N., Sahaf, B., Jones, C. D., Simen, B. B., Hanczaruk, B., Nguyen, K. D., Nadeau, K. C., Egholm, M., Miklos, D. B., Zehnder, J. L., & Fire, A. Z. (2009). Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing. Science Translational Medicine, 1(12). https://doi.org/10.1126/scitranslmed.3000540
PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance
Nature Medicine / Oct 18, 2009
Mukundan, L., Odegaard, J. I., Morel, C. R., Heredia, J. E., Mwangi, J. W., Ricardo-Gonzalez, R. R., Goh, Y. P. S., Eagle, A. R., Dunn, S. E., Awakuni, J. U. H., Nguyen, K. D., Steinman, L., Michie, S. A., & Chawla, A. (2009). PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance. Nature Medicine, 15(11), 1266–1272. https://doi.org/10.1038/nm.2048
Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements
The Journal of Immunology / Jun 15, 2010
Boyd, S. D., Gaëta, B. A., Jackson, K. J., Fire, A. Z., Marshall, E. L., Merker, J. D., Maniar, J. M., Zhang, L. N., Sahaf, B., Jones, C. D., Simen, B. B., Hanczaruk, B., Nguyen, K. D., Nadeau, K. C., Egholm, M., Miklos, D. B., Zehnder, J. L., & Collins, A. M. (2010). Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements. The Journal of Immunology, 184(12), 6986–6992. https://doi.org/10.4049/jimmunol.1000445
Eosinophils secrete IL-4 to facilitate liver regeneration
Proceedings of the National Academy of Sciences / May 28, 2013
Goh, Y. P. S., Henderson, N. C., Heredia, J. E., Red Eagle, A., Odegaard, J. I., Lehwald, N., Nguyen, K. D., Sheppard, D., Mukundan, L., Locksley, R. M., & Chawla, A. (2013). Eosinophils secrete IL-4 to facilitate liver regeneration. Proceedings of the National Academy of Sciences, 110(24), 9914–9919. https://doi.org/10.1073/pnas.1304046110
Oligoarticular and polyarticular JIA: epidemiology and pathogenesis
Nature Reviews Rheumatology / Oct 06, 2009
Macaubas, C., Nguyen, K., Milojevic, D., Park, J. L., & Mellins, E. D. (2009). Oligoarticular and polyarticular JIA: epidemiology and pathogenesis. Nature Reviews Rheumatology, 5(11), 616–626. https://doi.org/10.1038/nrrheum.2009.209
Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance
Cell Metabolism / Jan 01, 2016
Tian, X. Y., Ganeshan, K., Hong, C., Nguyen, K. D., Qiu, Y., Kim, J., Tangirala, R. K., Tontonoz, P., & Chawla, A. (2016). Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance. Cell Metabolism, 23(1), 165–178. https://doi.org/10.1016/j.cmet.2015.10.003
TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway
Allergy, Asthma & Clinical Immunology / Mar 15, 2010
Nguyen, K. D., Vanichsarn, C., & Nadeau, K. C. (2010). TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway. Allergy, Asthma & Clinical Immunology, 6(1). https://doi.org/10.1186/1710-1492-6-4
Selective deregulation in chemokine signaling pathways of CD4+CD25hiCD127lo/− regulatory T cells in human allergic asthma
Journal of Allergy and Clinical Immunology / Apr 01, 2009
Nguyen, K. D., Vanichsarn, C., Fohner, A., & Nadeau, K. C. (2009). Selective deregulation in chemokine signaling pathways of CD4+CD25hiCD127lo/− regulatory T cells in human allergic asthma. Journal of Allergy and Clinical Immunology, 123(4), 933-939.e10. https://doi.org/10.1016/j.jaci.2008.11.037
Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states
Clinical Immunology / Feb 01, 2010
Macaubas, C., Nguyen, K., Deshpande, C., Phillips, C., Peck, A., Lee, T., Park, J. L., Sandborg, C., & Mellins, E. D. (2010). Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states. Clinical Immunology, 134(2), 206–216. https://doi.org/10.1016/j.clim.2009.09.010
XCL1 Enhances Regulatory Activities of CD4+CD25highCD127low/− T Cells in Human Allergic Asthma
The Journal of Immunology / Oct 15, 2008
Nguyen, K. D., Fohner, A., Booker, J. D., Dong, C., Krensky, A. M., & Nadeau, K. C. (2008). XCL1 Enhances Regulatory Activities of CD4+CD25highCD127low/− T Cells in Human Allergic Asthma. The Journal of Immunology, 181(8), 5386–5395. https://doi.org/10.4049/jimmunol.181.8.5386
Alternative activation in systemic juvenile idiopathic arthritis monocytes
Clinical Immunology / Mar 01, 2012
Macaubas, C., Nguyen, K. D., Peck, A., Buckingham, J., Deshpande, C., Wong, E., Alexander, H. C., Chang, S.-Y., Begovich, A., Sun, Y., Park, J. L., Pan, K.-H., Lin, R., Lih, C.-J., Augustine, E. M., Phillips, C., Hadjinicolaou, A. V., Lee, T., & Mellins, E. D. (2012). Alternative activation in systemic juvenile idiopathic arthritis monocytes. Clinical Immunology, 142(3), 362–372. https://doi.org/10.1016/j.clim.2011.12.008
Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications
PROTEOMICS / Nov 23, 2010
Ling, X. B., Park, J. L., Carroll, T., Nguyen, K. D., Lau, K., Macaubas, C., Chen, E., Lee, T., Sandborg, C., Milojevic, D., Kanegaye, J. T., Gao, S., Burns, J., Schilling, J., & Mellins, E. D. (2010). Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications. PROTEOMICS, 10(24), 4415–4430. Portico. https://doi.org/10.1002/pmic.201000298
Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance
Mediators of Inflammation / Jan 01, 2015
Chng, M. H. Y., Alonso, M. N., Barnes, S. E., Nguyen, K. D., & Engleman, E. G. (2015). Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance. Mediators of Inflammation, 2015, 1–15. https://doi.org/10.1155/2015/593075
Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/– regulatory T cells in allergic asthma
European Journal of Immunology / Jun 25, 2008
Nguyen, K. D., Vanichsarn, C., & Nadeau, K. C. (2008). Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/– regulatory T cells in allergic asthma. European Journal of Immunology, 38(7), 2034–2045. Portico. https://doi.org/10.1002/eji.200738082
Altered phosphorylated signal transducer and activator of transcription profile of CD4+CD161+ T cells in asthma: Modulation by allergic status and oral corticosteroids
Journal of Allergy and Clinical Immunology / Dec 01, 2007
Gernez, Y., Tirouvanziam, R., Nguyen, K. D., Herzenberg, L. A., Krensky, A. M., & Nadeau, K. C. (2007). Altered phosphorylated signal transducer and activator of transcription profile of CD4+CD161+ T cells in asthma: Modulation by allergic status and oral corticosteroids. Journal of Allergy and Clinical Immunology, 120(6), 1441–1448. https://doi.org/10.1016/j.jaci.2007.08.012
Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development
Pediatric Rheumatology / Dec 01, 2008
Milojevic, D., Nguyen, K. D., Wara, D., & Mellins, E. D. (2008). Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development. Pediatric Rheumatology, 6(1). https://doi.org/10.1186/1546-0096-6-20
Altered signaling in systemic juvenile idiopathic arthritis monocytes
Clinical Immunology / Feb 01, 2016
Macaubas, C., Wong, E., Zhang, Y., Nguyen, K. D., Lee, J., Milojevic, D., Shenoi, S., Stevens, A. M., Ilowite, N., Saper, V., Lee, T., & Mellins, E. D. (2016). Altered signaling in systemic juvenile idiopathic arthritis monocytes. Clinical Immunology, 163, 66–74. https://doi.org/10.1016/j.clim.2015.12.011
Impaired IL-10–dependent Induction of Tolerogenic Dendritic Cells by CD4+CD25hiCD127lo/−Natural Regulatory T Cells in Human Allergic Asthma
American Journal of Respiratory and Critical Care Medicine / Nov 01, 2009
Nguyen, K. D., Vanichsarn, C., & Nadeau, K. C. (2009). Impaired IL-10–dependent Induction of Tolerogenic Dendritic Cells by CD4+CD25hiCD127lo/−Natural Regulatory T Cells in Human Allergic Asthma. American Journal of Respiratory and Critical Care Medicine, 180(9), 823–833. https://doi.org/10.1164/rccm.200905-0761oc
Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways
Blood / Apr 07, 2011
Nguyen, K. D., Macaubas, C., Nadeau, K. C., Truong, P., Yoon, T., Lee, T., Park, J. L., & Mellins, E. D. (2011). Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways. Blood, 117(14), 3793–3798. https://doi.org/10.1182/blood-2010-11-318832
Myeloid sphingosine-1-phosphate receptor 1 is important for CNS autoimmunity and neuroinflammation
Journal of Autoimmunity / Dec 01, 2019
Tsai, H.-C., Nguyen, K., Hashemi, E., Engleman, E., Hla, T., & Han, M. H. (2019). Myeloid sphingosine-1-phosphate receptor 1 is important for CNS autoimmunity and neuroinflammation. Journal of Autoimmunity, 105, 102290. https://doi.org/10.1016/j.jaut.2019.06.001
High-fat diet induces systemic B-cell repertoire changes associated with insulin resistance
Mucosal Immunology / Nov 01, 2017
Pham, T. D., Chng, M. H. Y., Roskin, K. M., Jackson, K. J. L., Nguyen, K. D., Glanville, J., Lee, J.-Y., Engleman, E. G., & Boyd, S. D. (2017). High-fat diet induces systemic B-cell repertoire changes associated with insulin resistance. Mucosal Immunology, 10(6), 1468–1479. https://doi.org/10.1038/mi.2017.25
Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation
Molecular Immunology / Jun 01, 2014
Nguyen, K. D., Macaubas, C., Truong, P., Wang, N., Hou, T., Yoon, T., & Mellins, E. D. (2014). Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation. Molecular Immunology, 59(2), 172–179. https://doi.org/10.1016/j.molimm.2014.02.011
Hyper/neuroinflammation in COVID-19 and suicide etiopathogenesis: Hypothesis for a nefarious collision?
Neuroscience & Biobehavioral Reviews / May 01, 2022
Costanza, A., Amerio, A., Aguglia, A., Serafini, G., Amore, M., Hasler, R., Ambrosetti, J., Bondolfi, G., Sampogna, G., Berardelli, I., Fiorillo, A., Pompili, M., & Nguyen, K. D. (2022). Hyper/neuroinflammation in COVID-19 and suicide etiopathogenesis: Hypothesis for a nefarious collision? Neuroscience & Biobehavioral Reviews, 136, 104606. https://doi.org/10.1016/j.neubiorev.2022.104606
Severe Suicidality in Athletes with Chronic Traumatic Encephalopathy: A Case Series and Overview on Putative Ethiopathogenetic Mechanisms
International Journal of Environmental Research and Public Health / Jan 20, 2021
Costanza, A., Radomska, M., Zenga, F., Amerio, A., Aguglia, A., Serafini, G., Amore, M., Berardelli, I., Ojio, Y., & Nguyen, K. D. (2021). Severe Suicidality in Athletes with Chronic Traumatic Encephalopathy: A Case Series and Overview on Putative Ethiopathogenetic Mechanisms. International Journal of Environmental Research and Public Health, 18(3), 876. https://doi.org/10.3390/ijerph18030876
Suicidality Associated With Deep Brain Stimulation in Extrapyramidal Diseases: A Critical Review and Hypotheses on Neuroanatomical and Neuroimmune Mechanisms
Frontiers in Integrative Neuroscience / Apr 08, 2021
Costanza, A., Radomska, M., Bondolfi, G., Zenga, F., Amerio, A., Aguglia, A., Serafini, G., Amore, M., Berardelli, I., Pompili, M., & Nguyen, K. D. (2021). Suicidality Associated With Deep Brain Stimulation in Extrapyramidal Diseases: A Critical Review and Hypotheses on Neuroanatomical and Neuroimmune Mechanisms. Frontiers in Integrative Neuroscience, 15. https://doi.org/10.3389/fnint.2021.632249
In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry
Rapid Communications in Mass Spectrometry / Feb 15, 2018
Sun, W., Nguyen, K. D., Fitch, W. L., Banister, S. D., Tang, H., Zhang, X., Yu, L., Engleman, E. G., & Rajadas, J. (2018). In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 32(6), 480–488. Portico. https://doi.org/10.1002/rcm.8060
Suicidality in Patients with Brain Tumors: A Brief Literature Review with Clinical Exemplar
Medicina / Dec 21, 2020
Costanza, A., Zenga, F., Rudà, R., Amerio, A., Aguglia, A., Serafini, G., Amore, M., Bondolfi, G., Berardelli, I., & Nguyen, K. D. (2020). Suicidality in Patients with Brain Tumors: A Brief Literature Review with Clinical Exemplar. Medicina, 56(12), 725. https://doi.org/10.3390/medicina56120725
Chloroquine/Hydroxychloroquine Use and Suicide Risk: Hypotheses for Confluent Etiopathogenetic Mechanisms?
Behavioral Sciences / Nov 07, 2021
Costanza, A., Placenti, V., Amerio, A., Aguglia, A., Serafini, G., Amore, M., Macchiarulo, E., Branca, F., Merli, R., Bondolfi, G., & Nguyen, K. D. (2021). Chloroquine/Hydroxychloroquine Use and Suicide Risk: Hypotheses for Confluent Etiopathogenetic Mechanisms? Behavioral Sciences, 11(11), 154. https://doi.org/10.3390/bs11110154
Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications
PROTEOMICS – Clinical Applications / Jul 29, 2011
Ling, X. B., Park, J. L., Carroll, T., Nguyen, K. D., Lau, K., Macaubas, C., Chen, E., Lee, T., Sandborg, C., Milojevic, D., Kanegaye, J. T., Gao, S., Burns, J., Schilling, J., & Mellins, E. D. (2011). Plasma profiles in active systemic juvenile idiopathic arthritis: Biomarkers and biological implications. PROTEOMICS – Clinical Applications, 5(7–8), 463–463. Portico. https://doi.org/10.1002/prca.201190039
Monocyte phenotypes in systemic juvenile idiopathic arthritis (44.13)
The Journal of Immunology / Apr 01, 2011
Macaubas, C., Nguyen, K., Peck, A., Wong, E., Buckingham, J., Goertz, Y., Deshpande, C., Alexander, H., Chang, S.-Y., Sun, Y., Park, J., Lee, T., Begovich, A., & Mellins, E. (2011). Monocyte phenotypes in systemic juvenile idiopathic arthritis (44.13). The Journal of Immunology, 186(1_Supplement), 44.13-44.13. https://doi.org/10.4049/jimmunol.186.supp.44.13
TSLP Directly Inhibits IL-10 Expression By Human Regulatory T Cells
Journal of Allergy and Clinical Immunology / Mar 01, 2008
Nguyen, K., & Nadeau, K. C. (2008). TSLP Directly Inhibits IL-10 Expression By Human Regulatory T Cells. Journal of Allergy and Clinical Immunology, 121(3), 791. https://doi.org/10.1016/j.jaci.2008.01.039
Lymphotactin Improves Treg Function in Asthmatics via the STAT5 Pathway
Clinical Immunology / Jan 01, 2007
Fohner, A., Nguyen, K., Krensky, A. M., & Nadeau, K. C. (2007). Lymphotactin Improves Treg Function in Asthmatics via the STAT5 Pathway. Clinical Immunology, 123, S77. https://doi.org/10.1016/j.clim.2007.03.397
Fundamental disincorporation and early non-inflammatory microglia alterations: Possible bridging phenomena between neurobiology and psychopathology in schizophrenia
Medical Hypotheses / Oct 01, 2023
Magnani, L., Fusar-Poli, L., Parise, A., Nguyen, K. D., Saverino, D., & Costanza, A. (2023). Fundamental disincorporation and early non-inflammatory microglia alterations: Possible bridging phenomena between neurobiology and psychopathology in schizophrenia. Medical Hypotheses, 179, 111158. https://doi.org/10.1016/j.mehy.2023.111158
Microglia and Other Cellular Mediators of Immunological Dysfunction in Schizophrenia: A Narrative Synthesis of Clinical Findings
Cells / Aug 19, 2023
Nguyen, K. D., Amerio, A., Aguglia, A., Magnani, L., Parise, A., Conio, B., Serafini, G., Amore, M., & Costanza, A. (2023). Microglia and Other Cellular Mediators of Immunological Dysfunction in Schizophrenia: A Narrative Synthesis of Clinical Findings. Cells, 12(16), 2099. https://doi.org/10.3390/cells12162099
Potential Infectious and Autoimmune Etiologies for Chronic Fatigue Syndrome
Chronic Fatigue Syndrome and the Body's Immune Defense System / Sep 20, 2002
Potential Infectious and Autoimmune Etiologies for Chronic Fatigue Syndrome. (2002). In Chronic Fatigue Syndrome and the Body’s Immune Defense System (pp. 49–59). CRC Press. https://doi.org/10.1201/b13956-7
CD4+ T regulatory cells mitogenic signaling is activated by IL-1 and IL-6 produced by serum amyloid A-stimulated monocytes (P1037)
The Journal of Immunology / May 01, 2013
Macaubas, C., Nguyen, K., Truong, P., Wang, N., Hou, T., Yoon, T., & Mellins, E. (2013). CD4+ T regulatory cells mitogenic signaling is activated by IL-1 and IL-6 produced by serum amyloid A-stimulated monocytes (P1037). The Journal of Immunology, 190(1_Supplement), 139.8-139.8. https://doi.org/10.4049/jimmunol.190.supp.139.8
Regulation of Expression, Function, and Inflammatory Responses of Innate Immune Receptor Toll-like Receptor-2 (TLR2) during Inflammatory Responses against Infection
YAKUGAKU ZASSHI / Dec 01, 2013
Shuto, T. (2013). Regulation of Expression, Function, and Inflammatory Responses of Innate Immune Receptor Toll-like Receptor-2 (TLR2) during Inflammatory Responses against Infection. YAKUGAKU ZASSHI, 133(12), 1401–1409. https://doi.org/10.1248/yakushi.13-00208
OR.6. Selective Deregulation in Chemokine Signaling Pathways of CD4+CD25hiCD127lo/-Regulatory T Cells in Human Allergic Asthma
Clinical Immunology / Jan 01, 2009
Nguyen, K., & Nadeau, K. (2009). OR.6. Selective Deregulation in Chemokine Signaling Pathways of CD4+CD25hiCD127lo/-Regulatory T Cells in Human Allergic Asthma. Clinical Immunology, 131, S7. https://doi.org/10.1016/j.clim.2009.03.013
OR.36. Lymphotactin Associated With Increased IL-10 and Decreased IL-4 Production in Treg, Not With Chemotaxis
Clinical Immunology / Jan 01, 2008
Fohner, A., Nguyen, K., & Nadeau, K. (2008). OR.36. Lymphotactin Associated With Increased IL-10 and Decreased IL-4 Production in Treg, Not With Chemotaxis. Clinical Immunology, 127, S15–S16. https://doi.org/10.1016/j.clim.2008.03.502
Distinct Molecular and Cellular Aspects of Systemic Juvenile Idiopathic Arthritis (SJIA) and Polyarticular (PolyJIA)
Clinical Immunology / Jan 01, 2007
Macaubas, C., Nguyen, K., Pan, K.-H., Lee, T., Deshpande, C., Sandborg, C., Cohen, S., & Mellins, E. (2007). Distinct Molecular and Cellular Aspects of Systemic Juvenile Idiopathic Arthritis (SJIA) and Polyarticular (PolyJIA). Clinical Immunology, 123, S94–S95. https://doi.org/10.1016/j.clim.2007.03.450
F.60. Differential Expression of Immune Parameters in Systemic Juvenile Idiopathic Arthritis (SJIA) Flare and Quiescence
Clinical Immunology / Jan 01, 2006
Nguyen, K., Macaubas, C., Deshpande, C., Lee, T., Sandborg, C., & Mellins, E. (2006). F.60. Differential Expression of Immune Parameters in Systemic Juvenile Idiopathic Arthritis (SJIA) Flare and Quiescence. Clinical Immunology, 119, S72. https://doi.org/10.1016/j.clim.2006.04.100
Education
Ph.D., Immunology / December, 2013
Stanford University
B.Sc., Biological Sciences / June, 2006
Experience
Tranquis Therapeutics
Founder / January, 2016 — Present
Tochikunda
Scientific Advisor / January, 2019 — January, 2022
Stanford Genome Technology Center
Scientific Consultant / January, 2024 — Present
Remegen
Director / December, 2020 — April, 2022
Stanford
Research Scientist / January, 2018 — January, 2019
Stanford University
Postdoctoral Fellow / February, 2014 — January, 2018
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