Thilini Perera

University of Illinois Chicago

Research Interests

Single-molecule Imaging
Superresolution Imaging
Analytical Separation
Mass Spectrometry
Pharmaceutical Science
Organic Chemistry
Biomedical Engineering
Biotechnology
Pharmacology
Bioengineering
Oncology
Hematology
Physical and Theoretical Chemistry
Health Informatics
Medical Laboratory Technology
Cancer Research
Biophysics
Biochemistry
Cell Biology
Immunology

Publications

GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms

Blood Cancer Journal / Nov 04, 2022

Geng, X., Wang, C., Gao, X., Chowdhury, P., Weiss, J., Villegas, J. A., Saed, B., Perera, T., Hu, Y., Reneau, J., Sverdlov, M., Wolfe, A., Brown, N., Harms, P., Bailey, N. G., Inamdar, K., Hristov, A. C., Tejasvi, T., Montes, J., … Wilcox, R. A. (2022). GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms. Blood Cancer Journal, 12(11). https://doi.org/10.1038/s41408-022-00745-y

Superresolution Imaging with Single-Antibody Labeling

Bioconjugate Chemistry / May 05, 2023

Gunasekara, H., Perera, T., Anderson, J., Saed, B., Ramseier, N., Keshta, N., & Hu, Y. S. (2023). Superresolution Imaging with Single-Antibody Labeling. Bioconjugate Chemistry, 34(5), 825–833. https://doi.org/10.1021/acs.bioconjchem.3c00178

Fluorescence Intermittency of Quantum Dot–Organic Dye Conjugates: Implications for Alternative Energy and Biological Imaging

The Journal of Physical Chemistry Letters / Apr 06, 2023

Chandrasiri, H. B., Jing, H., Perera, T., Hu, Y. S., & Snee, P. T. (2023). Fluorescence Intermittency of Quantum Dot–Organic Dye Conjugates: Implications for Alternative Energy and Biological Imaging. The Journal of Physical Chemistry Letters, 14(15), 3621–3626. https://doi.org/10.1021/acs.jpclett.3c00076

Single-molecule interaction microscopy reveals antibody binding kinetics

Sep 22, 2020

Perera, T., Gunasekara, H., & Hu, Y. S. (2020). Single-molecule interaction microscopy reveals antibody binding kinetics. https://doi.org/10.1101/2020.09.21.306605

Single‐Molecule Localization Microscopy Using Time‐Lapse Imaging of Single‐Antibody Labeling

Current Protocols / Oct 01, 2023

Perera, T., Gunasekara, H., & Hu, Y. S. (2023). Single‐Molecule Localization Microscopy Using Time‐Lapse Imaging of Single‐Antibody Labeling. Current Protocols, 3(10). Portico. https://doi.org/10.1002/cpz1.908

Increased vesicular dynamics and nanoscale clustering of IL-2 after T cell activation

Biophysical Journal / Mar 01, 2024

Saed, B., Ramseier, N. T., Perera, T., Anderson, J., Burnett, J., Gunasekara, H., Burgess, A., Jing, H., & Hu, Y. S. (2024). Increased vesicular dynamics and nanoscale clustering of IL-2 after T cell activation. Biophysical Journal. https://doi.org/10.1016/j.bpj.2024.03.029

GATA-3–dependent Gene Transcription is Impaired upon HDAC Inhibition

Clinical Cancer Research / Jan 02, 2024

Geng, X., Wang, C., Abdelrahman, S., Perera, T., Saed, B., Hu, Y. S., Wolfe, A., Reneau, J., Murga-Zamalloa, C., & Wilcox, R. A. (2024). GATA-3–dependent Gene Transcription is Impaired upon HDAC Inhibition. Clinical Cancer Research, 30(5), 1054–1066. https://doi.org/10.1158/1078-0432.ccr-23-1699

Single-molecule labeling achieves enhanced nanoscale imaging of F-actin in fragile membrane structures of dendritic cells

Biophysical Journal / Feb 01, 2024

Gunasekara Kalu Arachchige, H. T., Perera, T., Saed, B., & Hu, Y. (2024). Single-molecule labeling achieves enhanced nanoscale imaging of F-actin in fragile membrane structures of dendritic cells. Biophysical Journal, 123(3), 153a. https://doi.org/10.1016/j.bpj.2023.11.1048

Quantitative Superresolution Imaging of F-Actin in the Cell Body and Cytoskeletal Protrusions Using Phalloidin-Based Single-Molecule Labeling and Localization Microscopy

Mar 06, 2024

Gunasekara, H., Perera, T., Chao, C.-J., Bruno, J., Saed, B., Anderson, J., Zhao, Z., & Hu, Y. S. (2024). Quantitative Superresolution Imaging of F-Actin in the Cell Body and Cytoskeletal Protrusions Using Phalloidin-Based Single-Molecule Labeling and Localization Microscopy. https://doi.org/10.1101/2024.03.04.583337

GATA-3 Dependent Gene Transcription Is Impaired upon HDAC Inhibition

Blood / Nov 28, 2023

Geng, X., Wang, C., Perera, T., Saed, B., Hu, Y., Wolfe, A., Reneau, J. C., Murga-Zamalloa, C. A., & Wilcox, R. A. (2023). GATA-3 Dependent Gene Transcription Is Impaired upon HDAC Inhibition. Blood, 142(Supplement 1), 4357–4357. https://doi.org/10.1182/blood-2023-172509

Characterization of single-molecule dwell times beyond photobleaching

Single Molecule Spectroscopy and Superresolution Imaging XIII / Feb 13, 2020

Perera, T., Fu, W., & Hu, Y. S. (2020). Characterization of single-molecule dwell times beyond photobleaching. In I. Gregor, R. Erdmann, & F. Koberling (Eds.), Single Molecule Spectroscopy and Superresolution Imaging XIII. SPIE. https://doi.org/10.1117/12.2546920

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