Srividya Sundaresan

Ph.D. life science consultant and science communicator, with exceptional critical thinking, problem solving, research, and analytical abilities.

Research Interests

Pharmacology
Endocrinology
Neuroscience
Oncology
Cell Biology
Cancer Research

About

Dr. Srividya Sundaresan is a highly educated and experienced professional in the field of cellular and molecular biology. She earned her B. Pharm. degree from the University of Mumbai in 1991, where she received a strong foundation in the principles and practices of pharmaceutical sciences. After completing her undergraduate studies, Dr. Sundaresan pursued a Ph.D. in Molecular Pharmacology from Northwestern University, one of the top research institutions in the United States. Her doctoral research focused on the signal transduction pathways mediating hormone action. During her time at Northwestern, she gained extensive knowledge and expertise in areas such as endocrinology and cell biology. Following the completion of her Ph.D., Dr. Sundaresan completed a postdoctoral fellowship at Genentech Inc., in molecular oncology. In her current position, she is a scientific writer and clinical research program manager at CommonSpirit Health. In this role, she is responsible for developing and managing clinical research programs, as well as writing and editing scientific publications and reports. She also collaborates with cross-functional teams to design and implement clinical research and analyze data. Dr. Sundaresan's expertise in diverse areas such as endocrinology, oncology and neuroscience combined with advanced scientific communication skills brings a unique perspective to her work. She is highly valued for her knowledge, skills, and attention to detail in her work. Dr. Sundaresan is dedicated to advancing scientific research into human health and disease and improving the lives of patients through her contributions.

Publications

Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C.

Endocrinology / Jan 01, 1996

Sundaresan, S., Colin, I. M., Pestell, R. G., & Jameson, J. L. (1996). Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology, 137(1), 304–311. https://doi.org/10.1210/endo.137.1.8536629

Biological Response to ErbB Ligands in Nontransformed Cell Lines Correlates with a Specific Pattern of Receptor Expression

Endocrinology / Dec 01, 1998

Sundaresan, S., Roberts, P. E., King, K. L., Sliwkowski, M. X., & Mather, J. P. (1998). Biological Response to ErbB Ligands in Nontransformed Cell Lines Correlates with a Specific Pattern of Receptor Expression. Endocrinology, 139(12), 4756–4764. https://doi.org/10.1210/endo.139.12.6378

The biology of human epidermal growth factor receptor 2

Current Oncology Reports / Mar 01, 1999

Sundaresan, S., Penuel, E., & Sliwkowski, M. X. (1999). The biology of human epidermal growth factor receptor 2. Current Oncology Reports, 1(1), 16–22. https://doi.org/10.1007/s11912-999-0005-7

Expression of Ryanodine Receptors in the Pituitary Gland: Evidence for a Role in Gonadotropin-Releasing Hormone Signaling

Endocrinology / May 01, 1997

Sundaresan, S., Weiss, J., Bauer-Dantoin, A. C., & Jameson, J. L. (1997). Expression of Ryanodine Receptors in the Pituitary Gland: Evidence for a Role in Gonadotropin-Releasing Hormone Signaling. Endocrinology, 138(5), 2056–2065. https://doi.org/10.1210/endo.138.5.5153

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear

European Journal of Neuroscience / Jan 27, 2014

Mendus, D., Sundaresan, S., Grillet, N., Wangsawihardja, F., Leu, R., Müller, U., Jones, S. M., & Mustapha, M. (2014). Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear. European Journal of Neuroscience, 39(8), 1256–1267. Portico. https://doi.org/10.1111/ejn.12486

Sexually dimorphic transcriptional responses to gonadotropin-releasing hormone require chronic in vivo exposure to estradiol.

Endocrinology / Jun 01, 1996

Colin, I. M., Bauer-Dantoin, A. C., Sundaresan, S., Kopp, P., & Jameson, J. L. (1996). Sexually dimorphic transcriptional responses to gonadotropin-releasing hormone require chronic in vivo exposure to estradiol. Endocrinology, 137(6), 2300–2307. https://doi.org/10.1210/endo.137.6.8641179

Thyroid hormone is required for pruning, functioning and long‐term maintenance of afferent inner hair cell synapses

European Journal of Neuroscience / Oct 28, 2015

Sundaresan, S., Kong, J., Fang, Q., Salles, F. T., Wangsawihardja, F., Ricci, A. J., & Mustapha, M. (2015). Thyroid hormone is required for pruning, functioning and long‐term maintenance of afferent inner hair cell synapses. European Journal of Neuroscience, 43(2), 148–161. Portico. https://doi.org/10.1111/ejn.13081

A Lack of Immune System Genes Causes Loss in High Frequency Hearing but Does Not Disrupt Cochlear Synapse Maturation in Mice

PLoS ONE / May 07, 2014

Calton, M. A., Lee, D., Sundaresan, S., Mendus, D., Leu, R., Wangsawihardja, F., Johnson, K. R., & Mustapha, M. (2014). A Lack of Immune System Genes Causes Loss in High Frequency Hearing but Does Not Disrupt Cochlear Synapse Maturation in Mice. PLoS ONE, 9(5), e94549. https://doi.org/10.1371/journal.pone.0094549

Thyroid hormone is required for the pruning of afferent type II spiral ganglion neurons in the mouse cochlea

Neuroscience / Jan 01, 2016

Sundaresan, S., Balasubbu, S., & Mustapha, M. (2016). Thyroid hormone is required for the pruning of afferent type II spiral ganglion neurons in the mouse cochlea. Neuroscience, 312, 165–178. https://doi.org/10.1016/j.neuroscience.2015.11.020

A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements

Communications Biology / Nov 26, 2022

Kimmerling, R. J., Stevens, M. M., Olcum, S., Minnah, A., Vacha, M., LaBella, R., Ferri, M., Wasserman, S. C., Fujii, J., Shaheen, Z., Sundaresan, S., Ribadeneyra, D., Jayabalan, D. S., Agte, S., Aleman, A., Criscitiello, J. A., Niesvizky, R., Luskin, M. R., Parekh, S., … Reid, C. A. (2022). A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements. Communications Biology, 5(1). https://doi.org/10.1038/s42003-022-04270-3

Endovascular image-guided sampling of tumor-draining veins provides an enriched source of oncological biomarkers

Frontiers in Oncology / Mar 17, 2023

Tamrazi, A., Sundaresan, S., Gulati, A., Tan, F. J., Wadhwa, V., Bartlett, B. R., & Diaz, L. A. Jr. (2023). Endovascular image-guided sampling of tumor-draining veins provides an enriched source of oncological biomarkers. Frontiers in Oncology, 13. https://doi.org/10.3389/fonc.2023.916196

Abstract 5177: Ex vivo assessment of cellular mass response predicts clinical efficacy in solid tumors

Cancer Research / Mar 22, 2024

Kimmerling, R., Stevens, M., Olcum, S., Vacha, M., LaBella, R., Katsis, K., Aikens, R., Hannah, C., Guo, A., Fujii, J., Shaheen, Z., Sundaresan, S., Rainey, A., Blakely, A. M., Hernandez, J., Tamrazi, A., & Reid, C. (2024). Abstract 5177: Ex vivo assessment of cellular mass response predicts clinical efficacy in solid tumors. Cancer Research, 84(6_Supplement), 5177–5177. https://doi.org/10.1158/1538-7445.am2024-5177

Cellular Mass Response to Therapy Correlates With Clinical Response for a Range of Malignancies

JCO Precision Oncology / Feb 01, 2024

Stevens, M. M., Kimmerling, R. J., Olcum, S., Vacha, M., LaBella, R., Minnah, A., Katsis, K., Fujii, J., Shaheen, Z., Sundaresan, S., Criscitiello, J., Niesvizky, R., Raje, N., Branagan, A., Krishnan, A., Jagannath, S., Parekh, S., Sperling, A. S., Rosenbaum, C. A., … Reid, C. A. (2024). Cellular Mass Response to Therapy Correlates With Clinical Response for a Range of Malignancies. JCO Precision Oncology, 8. https://doi.org/10.1200/po.23.00349

Abstract 2176: A cell mass-based platform for characterizing immune cell function and response to checkpoint blockade in primary blood and malignant fluid samples

Cancer Research / Apr 04, 2023

Kimmerling, R., Stevens, M., Olcum, S., Minnah, A., Vacha, M., LaBella, R., Katsis, K., Guo, A., Fujii, J., Shaheen, Z., Sundaresan, S., Tamrazi, A., & Reid, C. (2023). Abstract 2176: A cell mass-based platform for characterizing immune cell function and response to checkpoint blockade in primary blood and malignant fluid samples. Cancer Research, 83(7_Supplement), 2176–2176. https://doi.org/10.1158/1538-7445.am2023-2176

Publisher Correction: A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements

Communications Biology / Jan 06, 2023

Kimmerling, R. J., Stevens, M. M., Olcum, S., Minnah, A., Vacha, M., LaBella, R., Ferri, M., Wasserman, S. C., Fujii, J., Shaheen, Z., Sundaresan, S., Ribadeneyra, D., Jayabalan, D. S., Agte, S., Aleman, A., Criscitiello, J. A., Niesvizky, R., Luskin, M. R., Parekh, S., … Reid, C. A. (2023). Publisher Correction: A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements. Communications Biology, 6(1). https://doi.org/10.1038/s42003-022-04376-8

Clinical value of CT-guided biopsy of small (≤1.5 cm) suspicious lung nodules: Diagnostic accuracy, molecular characterization and long-term clinical outcomes

Cancer Treatment and Research Communications / Jan 01, 2022

Tamrazi, A., Sundaresan, S., Parvizi, A., Eller, A., Fujii, J., Shaheen, Z., & Campbell, A. (2022). Clinical value of CT-guided biopsy of small (≤1.5 cm) suspicious lung nodules: Diagnostic accuracy, molecular characterization and long-term clinical outcomes. Cancer Treatment and Research Communications, 33, 100626. https://doi.org/10.1016/j.ctarc.2022.100626

Stimulation of mitogen-activated protein kinase by gonadotropin- releasing hormone: evidence for the involvement of protein kinase C

Endocrinology / Jan 01, 1996

Sundaresan, S. (1996). Stimulation of mitogen-activated protein kinase by gonadotropin- releasing hormone: evidence for the involvement of protein kinase C. Endocrinology, 137(1), 304–311. https://doi.org/10.1210/en.137.1.304

Education

Northwestern University

Ph.D., Molecular Pharmacology / June, 1997

Evanston, Illinois, United States of America

University of Mumbai

B. Pharm., Pharmaceutical Sciences / May, 1991

Mumbai

Experience

CommonSpirit Health

Scientific Writer and Clinical Research Program Manager / June, 2021Present

o Published cutting-edge clinical research in leading journals performing all functions from study design, data analysis, coordination with co-authors, and manuscript writing to journal submissions and peer-review responses. o Coordinated outreach and collaboration with academic partners and biotech startups to facilitate translational applications of innovations in liquid biopsy research. o Wrote clinical study protocols and amendments and supported getting institutional review board (IRB) approval. o Created website for the biopsy center (https://www.biopsycenter.org/).

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