After completing my BS in Biochemistry in Beirut, I pursued a master’s degree in Genetics followed by a Master 2 degree in Molecular Engineering. I received my PhD in Biochemistry and Biophysics in 2013 at Paris Descartes University with the highest honors & Committee Praise. Throughout my thesis and post-doctoral experience, I have studied different aspects of protein/nucleic acid interactions using several biophysical techniques.
Ph.D, Biochemistry Biophysics / January, 2013
A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes
Science / Apr 30, 2021
Sleiman, D., Garcia, P. S., Lagune, M., Loc’h, J., Haouz, A., Taib, N., Röthlisberger, P., Gribaldo, S., Marlière, P., & Kaminski, P. A. (2021). A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372(6541), 516–520. https://doi.org/10.1126/science.abe6494
Initiation of HIV-1 reverse transcription and functional role of nucleocapsid-mediated tRNA/viral genome interactions
Virus Research / Nov 01, 2012
Sleiman, D., Goldschmidt, V., Barraud, P., Marquet, R., Paillart, J.-C., & Tisné, C. (2012). Initiation of HIV-1 reverse transcription and functional role of nucleocapsid-mediated tRNA/viral genome interactions. Virus Research, 169(2), 324–339. https://doi.org/10.1016/j.virusres.2012.06.006
Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus
PLOS Genetics / Apr 16, 2018
Devaux, L., Sleiman, D., Mazzuoli, M.-V., Gominet, M., Lanotte, P., Trieu-Cuot, P., Kaminski, P.-A., & Firon, A. (2018). Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus. PLOS Genetics, 14(4), e1007342. https://doi.org/10.1371/journal.pgen.1007342
The Interaction between tRNALys3 and the Primer Activation Signal Deciphered by NMR Spectroscopy
PLoS ONE / Jun 06, 2013
Sleiman, D., Barraud, P., Brachet, F., & Tisne, C. (2013). The Interaction between tRNALys3 and the Primer Activation Signal Deciphered by NMR Spectroscopy. PLoS ONE, 8(6), e64700. https://doi.org/10.1371/journal.pone.0064700
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