Laura Schulze
Passionate mental health researcher with a PhD in Neuroscience, dedicated to fostering innovation and empathy in accessible and holistic mental health care.
Research Interests
About
Publications
The Efficacy of “Foundations,” a Digital Mental Health App to Improve Mental Well-being During COVID-19: Proof-of-Principle Randomized Controlled Trial
JMIR mHealth and uHealth / Jul 01, 2022
Catuara-Solarz, S., Skorulski, B., Estella-Aguerri, I., Avella-Garcia, C. B., Shepherd, S., Stott, E., Hemmings, N. R., Ruiz de Villa, A., Schulze, L., & Dix, S. (2022). The Efficacy of “Foundations,” a Digital Mental Health App to Improve Mental Well-being During COVID-19: Proof-of-Principle Randomized Controlled Trial. JMIR MHealth and UHealth, 10(7), e30976. https://doi.org/10.2196/30976
Cortico-Striatal-Thalamic Loop Circuits of the Orbitofrontal Cortex: Promising Therapeutic Targets in Psychiatric Illness
Frontiers in Systems Neuroscience / Apr 27, 2017
Fettes, P., Schulze, L., & Downar, J. (2017). Cortico-Striatal-Thalamic Loop Circuits of the Orbitofrontal Cortex: Promising Therapeutic Targets in Psychiatric Illness. Frontiers in Systems Neuroscience, 11. https://doi.org/10.3389/fnsys.2017.00025
Effect of antipsychotic pharmacotherapy on clinical outcomes of intermittent theta-burst stimulation for refractory depression
Journal of Psychopharmacology / Nov 11, 2016
Schulze, L., Remington, G., Giacobbe, P., Kennedy, S. H., Blumberger, D. M., Daskalakis, Z. J., & Downar, J. (2016). Effect of antipsychotic pharmacotherapy on clinical outcomes of intermittent theta-burst stimulation for refractory depression. Journal of Psychopharmacology, 31(3), 312–319. https://doi.org/10.1177/0269881116675516
Cognitive safety of dorsomedial prefrontal repetitive transcranial magnetic stimulation in major depression
European Neuropsychopharmacology / Jul 01, 2016
Schulze, L., Wheeler, S., McAndrews, M. P., Solomon, C. J. E., Giacobbe, P., & Downar, J. (2016). Cognitive safety of dorsomedial prefrontal repetitive transcranial magnetic stimulation in major depression. European Neuropsychopharmacology, 26(7), 1213–1226. https://doi.org/10.1016/j.euroneuro.2016.04.004
Number of pulses or number of sessions? An open-label study of trajectories of improvement for once-vs. twice-daily dorsomedial prefrontal rTMS in major depression
Brain Stimulation / Mar 01, 2018
Schulze, L., Feffer, K., Lozano, C., Giacobbe, P., Daskalakis, Z. J., Blumberger, D. M., & Downar, J. (2018). Number of pulses or number of sessions? An open-label study of trajectories of improvement for once-vs. twice-daily dorsomedial prefrontal rTMS in major depression. Brain Stimulation, 11(2), 327–336. https://doi.org/10.1016/j.brs.2017.11.002
Antipsychotic response in first-episode schizophrenia: efficacy of high doses and switching
European Neuropsychopharmacology / Sep 01, 2013
Agid, O., Schulze, L., Arenovich, T., Sajeev, G., McDonald, K., Foussias, G., Fervaha, G., & Remington, G. (2013). Antipsychotic response in first-episode schizophrenia: efficacy of high doses and switching. European Neuropsychopharmacology, 23(9), 1017–1022. https://doi.org/10.1016/j.euroneuro.2013.04.010
Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report
Neuropsychopharmacology / Apr 29, 2020
Dunlop, K., Rizvi, S. J., Kennedy, S. H., Hassel, S., Strother, S. C., Harris, J. K., Zamyadi, M., Arnott, S. R., Davis, A. D., Mansouri, F., Schulze, L., Ceniti, A. K., Lam, R. W., Milev, R., Rotzinger, S., Foster, J. A., Frey, B. N., Parikh, S. V., Soares, C. N., … Downar, J. (2020). Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report. Neuropsychopharmacology, 45(8), 1390–1397. https://doi.org/10.1038/s41386-020-0688-x
A Real-Time Phase-Locking System for Non-invasive Brain Stimulation
Frontiers in Neuroscience / Dec 03, 2018
Mansouri, F., Fettes, P., Schulze, L., Giacobbe, P., Zariffa, J., & Downar, J. (2018). A Real-Time Phase-Locking System for Non-invasive Brain Stimulation. Frontiers in Neuroscience, 12. https://doi.org/10.3389/fnins.2018.00877
Education
University of Toronto
PhD, Neuroscience / Neuropsychiatry / January, 2021
University of Toronto
MSc, Behavioural Neuroscience / November, 2014
University of Guelph
BA hons., Psychology / April, 2014
Experience
Koa Health
Consultant (R&D) / March, 2021 — January, 2023
Oversaw evidence generation, including the planning and execution of multi-site clinical trials for DTx
Loyal VC
Scientific Advisor / January, 2020 — Present
Provide support and advice for portfolio companies in STEM
Toronto Western Hospital
Doctoral Researcher / September, 2016 — January, 2021
Neuromodulation, biomarkers, large clinical trials for treatment of depression
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