Dr. Joshua Johnson, Ph.D.
Cambridge Postdoctoral Researcher with publications in DNA nanotechnology and experience with creating artificial cells.
Research Expertise
About
Publications
Mechanical design of DNA nanostructures
Nanoscale / Jan 01, 2015
Castro, C. E., Su, H.-J., Marras, A. E., Zhou, L., & Johnson, J. (2015). Mechanical design of DNA nanostructures. Nanoscale, 7(14), 5913–5921. https://doi.org/10.1039/c4nr07153k
Integrated computer-aided engineering and design for DNA assemblies
Nature Materials / Apr 19, 2021
Huang, C.-M., Kucinic, A., Johnson, J. A., Su, H.-J., & Castro, C. E. (2021). Integrated computer-aided engineering and design for DNA assemblies. Nature Materials, 20(9), 1264–1271. https://doi.org/10.1038/s41563-021-00978-5
Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies
Nano Letters / Oct 30, 2019
Johnson, J. A., Dehankar, A., Winter, J. O., & Castro, C. E. (2019). Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies. Nano Letters, 19(12), 8469–8475. https://doi.org/10.1021/acs.nanolett.9b02786
The path towards functional nanoparticle-DNA origami composites
Materials Science and Engineering: R: Reports / Oct 01, 2019
Johnson, J. A., Dehankar, A., Robbins, A., Kabtiyal, P., Jergens, E., Ho Lee, K., Johnston-Halperin, E., Poirier, M., Castro, C. E., & Winter, J. O. (2019). The path towards functional nanoparticle-DNA origami composites. Materials Science and Engineering: R: Reports, 138, 153–209. https://doi.org/10.1016/j.mser.2019.06.003
A quantitative model for a nanoscale switch accurately predicts thermal actuation behavior
Nanoscale / Jan 01, 2021
Crocker, K., Johnson, J., Pfeifer, W., Castro, C., & Bundschuh, R. (2021). A quantitative model for a nanoscale switch accurately predicts thermal actuation behavior. Nanoscale, 13(32), 13746–13757. https://doi.org/10.1039/d1nr02873a
Correction: Co-self-assembly of multiple DNA origami nanostructures in a single pot
Chemical Communications / Jan 01, 2022
Johnson, J. A., Kolliopoulos, V., & Castro, C. E. (2022). Correction: Co-self-assembly of multiple DNA origami nanostructures in a single pot. Chemical Communications, 58(5), 716–716. https://doi.org/10.1039/d1cc90444b
Probing Nucleosome Stability with a DNA Origami Nanocaliper
Probing Nucleosome Stability with a DNA Origami Nanocaliper. (n.d.). American Chemical Society (ACS). https://doi.org/10.1021/acsnano.6b03218.s001
Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies
Biophysical Journal / Feb 01, 2020
Johnson, J. A., Dehankar, A., Castro, C. E., & Winter, J. (2020). Reciprocal Control of Hierarchical DNA Origami-Nanoparticle Assemblies. Biophysical Journal, 118(3), 623a–624a. https://doi.org/10.1016/j.bpj.2019.11.3361
Erratum: “Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites” [J. Chem. Phys. 151, 144706 (2019)]
The Journal of Chemical Physics / Feb 03, 2020
Dehankar, A., Porter, T., Johnson, J. A., Castro, C. E., & Winter, J. O. (2020). Erratum: “Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites” [J. Chem. Phys. 151, 144706 (2019)]. The Journal of Chemical Physics, 152(5). https://doi.org/10.1063/1.5144924
Integrating computer-aided engineering and computer-aided design for DNA assemblies
May 30, 2020
Huang, C.-M., Kucinic, A., Johnson, J. A., Su, H.-J., & Castro, C. E. (2020). Integrating computer-aided engineering and computer-aided design for DNA assemblies. https://doi.org/10.1101/2020.05.28.119701
Self-Assembly of Geometry-Based DNA Origami-Histone Protein Hybrid Nanostructures for Constructing Rationally-Designed Higher-Order Structures
Self-Assembly of Geometry-Based DNA Origami-Histone Protein Hybrid Nanostructures for Constructing Rationally-Designed Higher-Order Structures. (n.d.). American Chemical Society (ACS). https://doi.org/10.1021/acsanm.3c01185.s001
Dynamic Control of DNA Origami Nanostructures via Gold Nanoparticles
Biophysical Journal / Feb 01, 2016
Johnson, J. A., Dehankar, A., Fan, Q., Winter, J., & Castro, C. (2016). Dynamic Control of DNA Origami Nanostructures via Gold Nanoparticles. Biophysical Journal, 110(3), 566a. https://doi.org/10.1016/j.bpj.2015.11.3030
Co-self-assembly of multiple DNA origami nanostructures in a single pot
Chemical Communications / Jan 01, 2021
Johnson, J. A., Kolliopoulos, V., & Castro, C. E. (2021). Co-self-assembly of multiple DNA origami nanostructures in a single pot. Chemical Communications, 57(39), 4795–4798. https://doi.org/10.1039/d1cc00049g
Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites
The Journal of Chemical Physics / Oct 10, 2019
Dehankar, A., Porter, T., Johnson, J. A., Castro, C. E., & Winter, J. O. (2019). Compact quantum dot surface modification to enable emergent behaviors in quantum dot-DNA composites. The Journal of Chemical Physics, 151(14). https://doi.org/10.1063/1.5124690
Education
Colorado School of Mines
MS Applied Physics, Physics
Colorado School of Mines
BS Physics Engineering, Physics / May, 2014
The Ohio State University
Ph.D., Biophysics / January, 2020
Experience
Imperial College London
Research Associate / March, 2020 — Present
Designed, built, and programmed custom instrumentation needed for precise and varied annealing protocols as cheaper and higher throughput alternative to existing equipment. Designed novel methods for integrating DNA nanomachines with artificial cells and nanopores for enhanced cancer detection
The Ohio State University
Graduate Research Associate / May, 2014 — February, 2020
Research focused on design and characterization of DNA origami nanomachines. Emphasis on combining organic and inorganic nanomaterials using thermal or optical inputs as control mechanisms for dynamic DNA nanostructures.
University of Cambridge
Postdoctoral Research Associate / October, 2022 — April, 2023
Transferred from Imperial College to continue with research in DNA nanotechnology. During the moving process I helped establish laboratory infrastructure including the development and approval of standard operating procedures and safety protocols to ensure compliance with regulations within the Department of Chemical Engineering and Biotechnology.
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