Animesh Roy

Expert in Organic synthesis, DNA encoded chemical libraries, Drug discovery and informatics

Research Interests

Organic
Organometallic Chemistry
Biochemistry
Organic Chemistry
Physical and Theoretical Chemistry
Immunology
Immunology and Allergy
Plant Science
Cell Biology
Drug Discovery
Materials Chemistry
Catalysis
Surfaces, Coatings and Films
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Metals and Alloys
Microbiology
Molecular Biology
Spectroscopy
Inorganic Chemistry
Computer Science Applications
Horticulture
Pharmacology
Toxicology

About

Results-oriented and highly adaptive chemist with experience in organic synthesis, large encoded chemical libraries, and proficient data wrangling. A seasoned researcher, committed to delivering impactful results by seamlessly integrating experimental data with rigorous analysis. Eager to contribute my expertise in both chemistry and informatics to challenging problems that aligns with my passion for innovation and scientific discovery.

Publications

Asymmetric Protonation of Cumulenolates: Synthesis of Allenyl Aldehydes Facilitated by an Organomanganese Auxiliary

Organic Letters / Feb 29, 2016

Roy, A., Bhat, B. A., & Lepore, S. D. (2016). Asymmetric Protonation of Cumulenolates: Synthesis of Allenyl Aldehydes Facilitated by an Organomanganese Auxiliary. Organic Letters, 18(6), 1230–1233. https://doi.org/10.1021/acs.orglett.5b03681

Organo-Manganese η2-Auxiliary Directed Reactions: A Diastereoselective Approach to 2,3-Allenols

Organic Letters / Feb 09, 2015

Roy, A., Bhat, B. A., & Lepore, S. D. (2015). Organo-Manganese η2-Auxiliary Directed Reactions: A Diastereoselective Approach to 2,3-Allenols. Organic Letters, 17(4), 900–903. https://doi.org/10.1021/ol503757h

Allenyl esters as quenching agents for ruthenium olefin metathesis catalysts

Tetrahedron Letters / Jan 01, 2017

Roy, A., Silvestri, M. A., Hall, R. A., & Lepore, S. D. (2017). Allenyl esters as quenching agents for ruthenium olefin metathesis catalysts. Tetrahedron Letters, 58(1), 106–108. https://doi.org/10.1016/j.tetlet.2016.11.121

Diversification reactions of γ-silyl allenyl esters: selective conversion to all-carbon quaternary centers and γ-allene dicarbinols

Chemical Communications / Jan 01, 2017

Jana, S., Roy, A., & Lepore, S. D. (2017). Diversification reactions of γ-silyl allenyl esters: selective conversion to all-carbon quaternary centers and γ-allene dicarbinols. Chemical Communications, 53(37), 5125–5127. https://doi.org/10.1039/c7cc01708a

ChemInform Abstract: Organo‐Manganese η2‐Auxiliary Directed Reactions: A Diastereoselective Approach to 2,3‐Allenols.

ChemInform / Jun 18, 2015

Roy, A., Bhat, B. A., & Lepore, S. D. (2015). ChemInform Abstract: Organo‐Manganese η2‐Auxiliary Directed Reactions: A Diastereoselective Approach to 2,3‐Allenols. ChemInform, 46(27). Portico. https://doi.org/10.1002/chin.201527067

Studies on the Manganese-Mediated Isomerization of Alkynyl Carbonyls to Allenyl Carbonyls

Studies on the Manganese-Mediated Isomerization of Alkynyl Carbonyls to Allenyl Carbonyls. (n.d.). American Chemical Society (ACS). https://doi.org/10.1021/jo051040u.s001

Synthesis and Screening of a DNA‐Encoded Library of Non‐Peptidic Macrocycles**

Angewandte Chemie International Edition / Mar 02, 2022

Koesema, E., Roy, A., Paciaroni, N. G., Coito, C., Tokmina‐Roszyk, M., & Kodadek, T. (2022). Synthesis and Screening of a DNA‐Encoded Library of Non‐Peptidic Macrocycles**. Angewandte Chemie International Edition, 61(18). Portico. https://doi.org/10.1002/anie.202116999

High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**

Angewandte Chemie International Edition / Apr 13, 2021

Roy, A., Koesema, E., & Kodadek, T. (2021). High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**. Angewandte Chemie International Edition, 60(21), 11983–11990. Portico. https://doi.org/10.1002/anie.202100230

High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**

Angewandte Chemie / Apr 14, 2021

Roy, A., Koesema, E., & Kodadek, T. (2021). High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**. Angewandte Chemie, 133(21), 12090–12097. Portico. https://doi.org/10.1002/ange.202100230

DELs Inside Cells

Trends in Pharmacological Sciences / Apr 01, 2020

Roy, A., & Kodadek, T. (2020). DELs Inside Cells. Trends in Pharmacological Sciences, 41(4), 225–227. https://doi.org/10.1016/j.tips.2020.01.007

High-Throughput Quality Control Assay for the Solid-Phase Syn-thesis of DNA-Encoded Libraries of Macrocycles

Dec 29, 2020

Roy, A., & Kodadek, T. (2020). High-Throughput Quality Control Assay for the Solid-Phase Syn-thesis of DNA-Encoded Libraries of Macrocycles. https://doi.org/10.26434/chemrxiv.13491312.v1

Synthesis and Screening of A DNA-Encoded Library of Non-Peptidic Macrocycles

Dec 29, 2020

Koesema, E., Roy, A., Paciaroni, N. G., & Kodadek, T. (2020). Synthesis and Screening of A DNA-Encoded Library of Non-Peptidic Macrocycles. https://doi.org/10.26434/chemrxiv.13490151.v1

Carbon-Carbon Bond Formation Facilitated by π-Complexed Organometallic Auxiliaries: An Overview

Letters in Organic Chemistry / Jul 05, 2019

Roy, A., Bhat, B. A., & Lepore, S. D. (2019). Carbon-Carbon Bond Formation Facilitated by π-Complexed Organometallic Auxiliaries: An Overview. Letters in Organic Chemistry, 16(9), 689–696. https://doi.org/10.2174/1570178616666181203141515

Experience

Plexium Inc

Scientist / May, 2021Present

Deluge Biotechnologies, Inc

Post-Doctoral Research associate / August, 2017April, 2021

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