Dr. Raja Mukherjee, Ph.D.
Senior Research Scientist at TCGLIFESCIENCES
Research Interests
About
Publications
A Precise Chemical Strategy To Alter the Receptor Specificity of the Adeno‐Associated Virus
Angewandte Chemie International Edition / Aug 02, 2016
Kelemen, R. E., Mukherjee, R., Cao, X., Erickson, S. B., Zheng, Y., & Chatterjee, A. (2016). A Precise Chemical Strategy To Alter the Receptor Specificity of the Adeno‐Associated Virus. Angewandte Chemie International Edition, 55(36), 10645–10649. Portico. https://doi.org/10.1002/anie.201604067
Defining the current scope and limitations of dual noncanonical amino acid mutagenesis in mammalian cells
Chemical Science / Jan 01, 2017
Zheng, Y., Addy, P. S., Mukherjee, R., & Chatterjee, A. (2017). Defining the current scope and limitations of dual noncanonical amino acid mutagenesis in mammalian cells. Chemical Science, 8(10), 7211–7217. https://doi.org/10.1039/c7sc02560b
Expanding the Scope of Single- and Double-Noncanonical Amino Acid Mutagenesis in Mammalian Cells Using Orthogonal Polyspecific Leucyl-tRNA Synthetases
Biochemistry / Nov 15, 2017
Zheng, Y., Mukherjee, R., Chin, M. A., Igo, P., Gilgenast, M. J., & Chatterjee, A. (2017). Expanding the Scope of Single- and Double-Noncanonical Amino Acid Mutagenesis in Mammalian Cells Using Orthogonal Polyspecific Leucyl-tRNA Synthetases. Biochemistry, 57(4), 441–445. https://doi.org/10.1021/acs.biochem.7b00952
Structure and synthesis of nudiflorine
Tetrahedron / Jan 01, 1966
Mukherjee, R., & Chatterjee, A. (1966). Structure and synthesis of nudiflorine. Tetrahedron, 22(4), 1461–1466. https://doi.org/10.1016/s0040-4020(01)99443-8
Precise Photoremovable Perturbation of a Virus–Host Interaction
Angewandte Chemie / Mar 15, 2017
Erickson, S. B., Mukherjee, R., Kelemen, R. E., Wrobel, C. J. J., Cao, X., & Chatterjee, A. (2017). Precise Photoremovable Perturbation of a Virus–Host Interaction. Angewandte Chemie, 129(15), 4298–4301. Portico. https://doi.org/10.1002/ange.201700683
Genetically Encoded Fragment-Based Discovery from Phage-Displayed Macrocyclic Libraries with Genetically Encoded Unnatural Pharmacophores
Journal of the American Chemical Society / Mar 30, 2021
Ekanayake, A. I., Sobze, L., Kelich, P., Youk, J., Bennett, N. J., Mukherjee, R., Bhardwaj, A., Wuest, F., Vukovic, L., & Derda, R. (2021). Genetically Encoded Fragment-Based Discovery from Phage-Displayed Macrocyclic Libraries with Genetically Encoded Unnatural Pharmacophores. Journal of the American Chemical Society, 143(14), 5497–5507. https://doi.org/10.1021/jacs.1c01186
Garratt–Braverman Cyclization, a Powerful Tool for C–C Bond Formation
Synlett / Oct 19, 2012
Basak, A., Mondal, S., Mitra, T., Mukherjee, R., & Addy, P. (2012). Garratt–Braverman Cyclization, a Powerful Tool for C–C Bond Formation. Synlett, 23(18), 2582–2602. https://doi.org/10.1055/s-0032-1317321
Selectivity in Garratt–Braverman Cyclization of Aryl-/Heteroaryl-Substituted Unsymmetrical Bis-Propargyl Systems: Formal Synthesis of 7′-Desmethylkealiiquinone
The Journal of Organic Chemistry / Apr 14, 2014
Das, J., Mukherjee, R., & Basak, A. (2014). Selectivity in Garratt–Braverman Cyclization of Aryl-/Heteroaryl-Substituted Unsymmetrical Bis-Propargyl Systems: Formal Synthesis of 7′-Desmethylkealiiquinone. The Journal of Organic Chemistry, 79(9), 3789–3798. https://doi.org/10.1021/jo402749d
Reactivity of Bispropargyl Sulfones under Basic Conditions: Interplay Between Garratt–Braverman and Schmittel/Myers–Saito Cyclization Pathway
Chemistry – An Asian Journal / Mar 07, 2012
Mukherjee, R., Mondal, S., Basak, A., Mallick, D., & Jemmis, E. D. (2012). Reactivity of Bispropargyl Sulfones under Basic Conditions: Interplay Between Garratt–Braverman and Schmittel/Myers–Saito Cyclization Pathway. Chemistry – An Asian Journal, 7(5), 957–965. Portico. https://doi.org/10.1002/asia.201100903
Genetically-encoded discovery of proteolytically stable bicyclic inhibitors for morphogen NODAL
Chemical Science / Jan 01, 2021
Wong, J. Y.-K., Mukherjee, R., Miao, J., Bilyk, O., Triana, V., Miskolzie, M., Henninot, A., Dwyer, J. J., Kharchenko, S., Iampolska, A., Volochnyuk, D. M., Lin, Y.-S., Postovit, L.-M., & Derda, R. (2021). Genetically-encoded discovery of proteolytically stable bicyclic inhibitors for morphogen NODAL. Chemical Science, 12(28), 9694–9703. https://doi.org/10.1039/d1sc01916c
A self-organizing fuzzy inference system for electric field optimization of HV electrode systems
IEEE Transactions on Dielectrics and Electrical Insulation / Dec 01, 2001
Chatterjee, A., Rakshit, A., & Mukherjee, R. K. (2001). A self-organizing fuzzy inference system for electric field optimization of HV electrode systems. IEEE Transactions on Dielectrics and Electrical Insulation, 8(6), 995–1002. https://doi.org/10.1109/94.971456
Synthesis of 1-Indol-3-yl-carbazoles via Garratt-Braverman Cyclization
Synlett / Mar 15, 2012
Basak, A., & Mukherjee, R. (2012). Synthesis of 1-Indol-3-yl-carbazoles via Garratt-Braverman Cyclization. Synlett, 23(06), 877–880. https://doi.org/10.1055/s-0031-1290606
The chemistry of securinine, an alkaloid of the root of securinega suffruticosa (Pall.) rehd
Die Naturwissenschaften / Jan 01, 1963
B. Das, R. M., Arya, V. P., & Chatterjee, A. (1963). The chemistry of securinine, an alkaloid of the root of securinega suffruticosa (Pall.) rehd. Die Naturwissenschaften, 50(5), 155–155. https://doi.org/10.1007/bf00623072
Genetically Encoded Fragment-Based Discovery (GE-FBD) from Phage-Displayed Macrocyclic Libraries with Genetically-Encoded Unnatural Pharmacophores
Jul 13, 2020
EKANAYAKE, A., Sobze, L., Youk, J., Bennett, N. J., Mukherjee, R., Bhardwaj, A., Wuest, F., & Derda, R. (2020). Genetically Encoded Fragment-Based Discovery (GE-FBD) from Phage-Displayed Macrocyclic Libraries with Genetically-Encoded Unnatural Pharmacophores. https://doi.org/10.26434/chemrxiv.12644225
Tandem Wittig/Diels–Alder diversification of genetically encoded peptide libraries
Organic & Biomolecular Chemistry / Jan 01, 2017
Triana, V., & Derda, R. (2017). Tandem Wittig/Diels–Alder diversification of genetically encoded peptide libraries. Organic & Biomolecular Chemistry, 15(37), 7869–7877. https://doi.org/10.1039/c7ob01635b
Production and Chemoselective Modification of Adeno-Associated Virus Site-Specifically Incorporating an Unnatural Amino Acid Residue into Its Capsid
Methods in Molecular Biology / Jan 01, 2018
Kelemen, R. E., Erickson, S. B., & Chatterjee, A. (2018). Production and Chemoselective Modification of Adeno-Associated Virus Site-Specifically Incorporating an Unnatural Amino Acid Residue into Its Capsid. In Noncanonical Amino Acids (pp. 313–326). Springer New York. https://doi.org/10.1007/978-1-4939-7574-7_20
Development of an ‘Automated’ Cad Model Generation of Globally Optimized Container Ship Design
Design & Operation of Container Ships 2014 / May 21, 2014
Chauhan, A., & Chauhan, U. (2014, May 21). Development of an ‘Automated’ Cad Model Generation of Globally Optimized Container Ship Design. Design & Operation of Container Ships 2014. https://doi.org/10.3940/rina.con.2014.04
Genetically-Encoded Discovery of Proteolytically Stable Bicyclic Inhibitors of Morphogen NODAL
Feb 11, 2021
Wong, J. Y. K., Mukherjee, R., Bilyk, O., Miao, J., Triana, V., Miskolzie, M., Lin, Y.-S., Henninot, A., Dwyer, J., Kharchenko, S., Iampolska, A., Volochnyuk, D., Postovit, J. J., & Derda, R. (2021). Genetically-Encoded Discovery of Proteolytically Stable Bicyclic Inhibitors of Morphogen NODAL. https://doi.org/10.26434/chemrxiv.13870592.v1
Precise Photoremovable Perturbation of a Virus–Host Interaction
Angewandte Chemie International Edition / Mar 15, 2017
Erickson, S. B., Mukherjee, R., Kelemen, R. E., Wrobel, C. J. J., Cao, X., & Chatterjee, A. (2017). Precise Photoremovable Perturbation of a Virus–Host Interaction. Angewandte Chemie International Edition, 56(15), 4234–4237. Portico. https://doi.org/10.1002/anie.201700683
Sodium sulfide in methanol: a two-in-one reagent for deprotection of silyl and formation of propargyl sulfide
Tetrahedron Letters / Jul 01, 2015
Hatial, I., Mukherjee, R., Senapati, K., & Basak, A. (2015). Sodium sulfide in methanol: a two-in-one reagent for deprotection of silyl and formation of propargyl sulfide. Tetrahedron Letters, 56(29), 4275–4279. https://doi.org/10.1016/j.tetlet.2015.04.104
Education
Indian Institute of Technology Kharagpur
PhD, Chemistry / July, 2014
Indian Institute of Technology (Indian School of Mines), Dhanbad
MSc, Chemistry / June, 2008
University of Burdwan
BSc, Chemistry / May, 2006
Experience
TCGLIFESCIENCES
Senior Research Scientist / September, 2019 — Present
University of Alberta
Post Doctoral Research Fellow / November, 2016 — July, 2019
Boston College
Post Doctoral Research Fellow / July, 2014 — December, 2015
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