•My current research expertise - Plant Genetic Engineering, plant-based pharmaceutical compounds as integrative treatment options for cancer, mammalian and plant tissue culture, agrigenomics, bioinformatics aimed at molecular evolution of cancer protein domains, and phytoremediation to reclaim cultivable land near oil fields. •My transferable research skills - molecular biology, cancer biology, phytopharmaceuticals, plant biotechnology, and bioinformatics On the personal side....I am a natural storyteller and more specifically a "Science Storyteller" and am passionate about promoting citizen science. I am also a bibliophile (I read books with any interesting subject...my favorites being THE DOUBLE HELIX (by James Watson), THE COMPLETE WORKS OF O. HENRY, ZEN AND THE ART OF MOTORCYCLE MAINTENANCE, THE HITCHHIKER'S GUIDE TO GALAXY, and THE FOUNTAINHEAD....in that order!!!). My free time is devoted to the three M's...MUSIC, MOLECULAR BIOLOGY, and MOVIES.
Chandrakanth Emani
Research Scientist at MaxGene BioScience
Research Expertise
About
Publications
Enhanced fungal resistance in transgenic cotton expressing an endochitinase gene from Trichoderma virens
Plant Biotechnology Journal / Sep 01, 2003
Emani, C., Garcia, J. M., Lopata‐Finch, E., Pozo, M. J., Uribe, P., Kim, D., Sunilkumar, G., Cook, D. R., Kenerley, C. M., & Rathore, K. S. (2003). Enhanced fungal resistance in transgenic cotton expressing an endochitinase gene from Trichoderma virens. Plant Biotechnology Journal, 1(5), 321–336. Portico. https://doi.org/10.1046/j.1467-7652.2003.00029.x
Genome Editing in Plants: An Overview of Tools and Applications
International Journal of Agronomy / Jan 01, 2017
Kamburova, V. S., Nikitina, E. V., Shermatov, S. E., Buriev, Z. T., Kumpatla, S. P., Emani, C., & Abdurakhmonov, I. Y. (2017). Genome Editing in Plants: An Overview of Tools and Applications. International Journal of Agronomy, 2017, 1–15. https://doi.org/10.1155/2017/7315351
Transgene silencing and reactivation in sorghum
Plant Science / Feb 01, 2002
Emani, C., Sunilkumar, G., & Rathore, K. S. (2002). Transgene silencing and reactivation in sorghum. Plant Science, 162(2), 181–192. https://doi.org/10.1016/s0168-9452(01)00559-3
Sugarcane DIRIGENT and O-METHYLTRANSFERASE promoters confer stem-regulated gene expression in diverse monocots
Planta / Mar 30, 2010
Damaj, M. B., Kumpatla, S. P., Emani, C., Beremand, P. D., Reddy, A. S., Rathore, K. S., Buenrostro-Nava, M. T., Curtis, I. S., Thomas, T. L., & Mirkov, T. E. (2010). Sugarcane DIRIGENT and O-METHYLTRANSFERASE promoters confer stem-regulated gene expression in diverse monocots. Planta, 231(6), 1439–1458. https://doi.org/10.1007/s00425-010-1138-5
Sugarcane DIRIGENT and O-METHYLTRANSFERASE promoters confer stem-regulated gene expression in diverse monocots
Planta / Mar 30, 2010
Damaj, M. B., Kumpatla, S. P., Emani, C., Beremand, P. D., Reddy, A. S., Rathore, K. S., Buenrostro-Nava, M. T., Curtis, I. S., Thomas, T. L., & Mirkov, T. E. (2010). Sugarcane DIRIGENT and O-METHYLTRANSFERASE promoters confer stem-regulated gene expression in diverse monocots. Planta, 231(6), 1439–1458. https://doi.org/10.1007/s00425-010-1138-5
Role of MicroRNAs and small RNAs in regulation of developmental processes and agronomic traits in Gossypium species
Genomics / Sep 01, 2019
Ayubov, M. S., Mirzakhmedov, M. H., Sripathi, V. R., Buriev, Z. T., Ubaydullaeva, K. A., Usmonov, D. E., Norboboyeva, R. B., Emani, C., Kumpatla, S. P., & Abdurakhmonov, I. Y. (2019). Role of MicroRNAs and small RNAs in regulation of developmental processes and agronomic traits in Gossypium species. Genomics, 111(5), 1018–1025. https://doi.org/10.1016/j.ygeno.2018.07.012
Phaseolin: Structure and Evolution
The Open Evolution Journal / Jan 01, 2008
Emani, C., & Hall, T. C. (2008). Phaseolin: Structure and Evolution. The Open Evolution Journal, 1(1), 66–74. https://doi.org/10.2174/1874404400802010066
The Effects of Transgenic Crops on Non-target Organisms
Sustainable Development and Biodiversity / Jan 01, 2014
Emani, C. (2014). The Effects of Transgenic Crops on Non-target Organisms. In Biotechnology and Biodiversity (pp. 59–66). Springer International Publishing. https://doi.org/10.1007/978-3-319-09381-9_4
Insect Resistance
Genomics and Breeding for Climate-Resilient Crops / Jan 01, 2013
Emani, C., & Hunter, W. (2013). Insect Resistance. In Genomics and Breeding for Climate-Resilient Crops (pp. 315–332). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-37048-9_9
Transgenic Cotton for Agronomical Useful Traits
Sustainable Development and Biodiversity / Jan 01, 2016
Emani, C. (2016). Transgenic Cotton for Agronomical Useful Traits. In Fiber Plants (pp. 201–216). Springer International Publishing. https://doi.org/10.1007/978-3-319-44570-0_10
Using the “DNA Story” to Inculcate a Scientific Thought Process in the Classroom
The American Biology Teacher / Sep 01, 2010
Emani, C. (2010). Using the “DNA Story” to Inculcate a Scientific Thought Process in the Classroom. The American Biology Teacher, 72(7), 410–413. https://doi.org/10.1525/abt.2010.72.7.4
Identification of Traits, Genes, and Crops of the Future
Genomics and Breeding for Climate-Resilient Crops / Jan 01, 2013
De Pace, C., Ricciardi, L., Kumar, A., Pavan, S., Lotti, C., Dixit, S., & Emani, C. (2013). Identification of Traits, Genes, and Crops of the Future. In Genomics and Breeding for Climate-Resilient Crops (pp. 27–177). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-37045-8_3
The Biology of Plant-Insect Interactions
Mar 05, 2018
Emani, C. (Ed.). (2018, March 5). The Biology of Plant-Insect Interactions: A Compendium for the Plant Biotechnologist. CRC Press. https://doi.org/10.1201/9781315119571
Prolotherapy agent P2G is associated with upregulation of fibroblast growth factor-2 genetic expression in vitro
Journal of Experimental Orthopaedics / Dec 01, 2020
Johnston, E., Emani, C., Kochan, A., Ghebrehawariat, K., Tyburski, J., Johnston, M., & Rabago, D. (2020). Prolotherapy agent P2G is associated with upregulation of fibroblast growth factor-2 genetic expression in vitro. Journal of Experimental Orthopaedics, 7(1). https://doi.org/10.1186/s40634-020-00312-z
Gossypium
Wild Crop Relatives: Genomic and Breeding Resources / Jan 01, 2011
Emani, C. (2011). Gossypium. In Wild Crop Relatives: Genomic and Breeding Resources (pp. 109–122). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-21102-7_6
The Coevolution of the Plant-Insect Interaction Networks
The Biology of Plant-Insect Interactions / Mar 05, 2018
Corneal, K., Campbell, J., Evans, N., & Emani, C. (2018). The Coevolution of the Plant-Insect Interaction Networks. In The Biology of Plant-Insect Interactions (pp. 74–92). CRC Press. https://doi.org/10.1201/9781315119571-4
Metabolic Engineering of Pathways and Gene Discovery
Transgenic Crop Plants / Jan 01, 2010
Juříček, M., Emani, C., Kertbundit, S., & Hall, T. C. (2010). Metabolic Engineering of Pathways and Gene Discovery. In Transgenic Crop Plants (pp. 275–306). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-04809-8_10
Figure 1. Comparison of protein coding genes in the genomes of JCVI-syn3A (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/CP016816.2 (Glass, 2017)), M. pneumoniae (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/U00089.2 (Himmelreich et al., 2014)), and E. coli (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/NC_012967.1 (Jeong et al., 2017)) with 452, 688, and 4637 coding genes, respectively.
Figure 1. Comparison of protein coding genes in the genomes of JCVI-syn3A (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/CP016816.2 (Glass, 2017)), M. pneumoniae (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/U00089.2 (Himmelreich et al., 2014)), and E. coli (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/NC_012967.1 (Jeong et al., 2017)) with 452, 688, and 4637 coding genes, respectively.: Each color represents a primary functional class, each contiguous shaded region corresponds to a secondary functional class, within each of the shaded regions the bold lines separate tertiary functional classes, finally each polygonal cell represents a single gene. The functional class hierarchy is presented in Supplementary file 1A. The ratio of metabolic to genetic information processing genes—0.67, 0.79, and 2.23 respectively—is smallest for JCVI-syn3A. The JCVI-syn3A genome contains both the smallest absolute number of genes of unclear function and the smallest percentage, 91 (20 %), compared to M. pneumoniae with 311 (45 %) and E. coli with 1780 (38 %). (n.d.). eLife Sciences Publications, Ltd. https://doi.org/10.7554/elife.36842.003
Figure 1. Comparison of protein coding genes in the genomes of JCVI-syn3A (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/CP016816.2 (Glass, 2017)), M. pneumoniae (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/U00089.2 (Himmelreich et al., 2014)), and E. coli (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/NC_012967.1 (Jeong et al., 2017)) with 452, 688, and 4637 coding genes, respectively.
Figure 1. Comparison of protein coding genes in the genomes of JCVI-syn3A (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/CP016816.2 (Glass, 2017)), M. pneumoniae (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/U00089.2 (Himmelreich et al., 2014)), and E. coli (NCBI GenBank: https://www.ncbi.nlm.nih.gov/nuccore/NC_012967.1 (Jeong et al., 2017)) with 452, 688, and 4637 coding genes, respectively.: Each color represents a primary functional class, each contiguous shaded region corresponds to a secondary functional class, within each of the shaded regions the bold lines separate tertiary functional classes, finally each polygonal cell represents a single gene. The functional class hierarchy is presented in Supplementary file 1A. The ratio of metabolic to genetic information processing genes—0.67, 0.79, and 2.23 respectively—is smallest for JCVI-syn3A. The JCVI-syn3A genome contains both the smallest absolute number of genes of unclear function and the smallest percentage, 91 (20 %), compared to M. pneumoniae with 311 (45 %) and E. coli with 1780 (38 %). (n.d.). eLife Sciences Publications, Ltd. https://doi.org/10.7554/elife.36842.003
Prolotherapy upregulates Fibroblast Growth Factor‐2 (FGF‐2) and Insulin‐like Growth Factor‐1 (IGF‐1) mRNA which may increase chondrocyte proliferation and mediates osteoarthritic inflammation
The FASEB Journal / Apr 01, 2020
Johnston, E. D., & Emani, C. (2020). Prolotherapy upregulates Fibroblast Growth Factor‐2 (FGF‐2) and Insulin‐like Growth Factor‐1 (IGF‐1) mRNA which may increase chondrocyte proliferation and mediates osteoarthritic inflammation. The FASEB Journal, 34(S1), 1–1. Portico. https://doi.org/10.1096/fasebj.2020.34.s1.09039
Transgenic approaches to combatting insect pests in the field
The Biology of Plant-Insect Interactions / Mar 05, 2018
Campbell, J., Veizaj, J., Evans, N., Taylor, S., & Emani, C. (2018). Transgenic approaches to combatting insect pests in the field. In The Biology of Plant-Insect Interactions (pp. 113–128). CRC Press. https://doi.org/10.1201/9781315119571-6
Genetic, Biochemical and Molecular Networks of Plant-Insect Interactions–Model Platforms for Integrative Biological Research
The Biology of Plant-Insect Interactions / Mar 05, 2018
Lasher, J., Speer, A., Taylor, S., & Emani, C. (2018). Genetic, Biochemical and Molecular Networks of Plant-Insect Interactions–Model Platforms for Integrative Biological Research. In The Biology of Plant-Insect Interactions (pp. 48–61). CRC Press. https://doi.org/10.1201/9781315119571-2
MEvoLib v1.0: the first molecular evolution library for Python
BMC Bioinformatics / Oct 28, 2016
Álvarez-Jarreta, J., & Ruiz-Pesini, E. (2016). MEvoLib v1.0: the first molecular evolution library for Python. BMC Bioinformatics, 17(1). https://doi.org/10.1186/s12859-016-1303-3
Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer
BMC Bioinformatics / May 26, 2016
Zhang, L., Yuan, Y., Lu, K. H., & Zhang, L. (2016). Identification of recurrent focal copy number variations and their putative targeted driver genes in ovarian cancer. BMC Bioinformatics, 17(1). https://doi.org/10.1186/s12859-016-1085-7
Proceedings of the Fourteenth Annual UT- KBRIN Bioinformatics Summit 2015
BMC Bioinformatics / Oct 23, 2015
Rouchka, E. C., Chariker, J. H., & Harrison, B. J. (2015). Proceedings of the Fourteenth Annual UT- KBRIN Bioinformatics Summit 2015. BMC Bioinformatics, 16(S15). https://doi.org/10.1186/1471-2105-16-s15-i1
Transgenic Crops to Preserve Biodiversity
Sustainable Development and Biodiversity / Jan 01, 2014
Emani, C. (2014). Transgenic Crops to Preserve Biodiversity. In Biotechnology and Biodiversity (pp. 3–15). Springer International Publishing. https://doi.org/10.1007/978-3-319-09381-9_1
Education Posters
In Vitro Cellular & Developmental Biology - Animal / May 18, 2013
Education Posters. (2013). In Vitro Cellular & Developmental Biology - Animal, 49(S1), 47–49. https://doi.org/10.1007/s11626-013-9606-4
Focused Plant Biotechnological Research to Preserve Biodiversity
Journal of Biodiversity Management & Forestry / Jan 01, 2013
Emani, C. (2013). Focused Plant Biotechnological Research to Preserve Biodiversity. Journal of Biodiversity Management & Forestry, 01(01). https://doi.org/10.4172/2327-4417.1000e102
Education
Osmania University
Ph D, Genetics and Plant Molecular Biology, Center for Plant Molecular Biology, Department of Genetics / March, 1997
University of Pune
M.Sc., Biochemistry, Biochemistry / May, 1991
Nizam College
B.Sc. Genetics, Zoology, Chemistry, Genetics / May, 1989
Experience
Western Kentucky University
Associate Professor / January, 2010 — September, 2023
Teaching and research in plant molecular biology, biotechnology, genetics, biochemistry and bioinformatics
Research Scientist - MaxGene BioScience / October, 2023 — Present
R&D - CRISPR editing and genetic engineering
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