Ramy Ayoub

Ph.D. Candidate, University of Toronto | SickKids Hospital

About

Ramy Ayoub is a PhD candidate at the University of Toronto in the department of Medical Biophysics. His research focuses on the development of treatment strategies to limit long-term negative complications in brain tumour survivors treated with radiation therapy. Ramy addresses his thesis work by conducting genetic, pharmacological, and neuroimaging studies on mouse models for paediatric radiotherapy. Ramy has authored numerous scientific publications and is a recipient of several awards, including the Brain Star award for excellence in Canadian research. Ramy has passion for advancing science innovation through collaborative efforts across academia and industry.

Education

University of Toronto

PhD, Medical Biophysics

Toronto

Wilfrid Laurier University

Biological Psychology, Neuroscience / April, 2017

Waterloo

Experience

Hospital for Sick Children

PhD Scientific Researcher / September, 2018 — Present

Publications

Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin

Nature Medicine / Jul 27, 2020

Ayoub, R., Ruddy, R. M., Cox, E., Oyefiade, A., Derkach, D., Laughlin, S., Ades-aron, B., Shirzadi, Z., Fieremans, E., MacIntosh, B. J., de Medeiros, C. B., Skocic, J., Bouffet, E., Miller, F. D., Morshead, C. M., & Mabbott, D. J. (2020). Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin. Nature Medicine, 26(8), 1285–1294. https://doi.org/10.1038/s41591-020-0985-2

Unified rhombic lip origins of group 3 and group 4 medulloblastoma

Nature / Sep 21, 2022

Smith, K. S., Bihannic, L., Gudenas, B. L., Haldipur, P., Tao, R., Gao, Q., Li, Y., Aldinger, K. A., Iskusnykh, I. Y., Chizhikov, V. V., Scoggins, M., Zhang, S., Edwards, A., Deng, M., Glass, I. A., Overman, L. M., Millman, J., Sjoboen, A. H., Hadley, J., … Northcott, P. A. (2022). Unified rhombic lip origins of group 3 and group 4 medulloblastoma. Nature, 609(7929), 1012–1020. https://doi.org/10.1038/s41586-022-05208-9

Out of sight, out of mind: mechanisms of social choice in fish

Animal Behaviour / Sep 01, 2019

Ayoub, R., Armstrong, E., & Miller, N. Y. (2019). Out of sight, out of mind: mechanisms of social choice in fish. Animal Behaviour, 155, 163–169. https://doi.org/10.1016/j.anbehav.2019.05.025

Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation

Radiation Research / Jul 16, 2021

Ayoub, R., Lau, K., Yuen, N., Fernandes, D., Elder, M., Yeung, J., Wong, S. C., & Nieman, B. J. (2021). Spatiotemporal Mapping of Early Volume Loss in the Mouse Brain after Cranial Irradiation. Radiation Research, 196(4). https://doi.org/10.1667/rade-21-00013.1

QOL-53. METFORMIN RESULTS IN HIPPOCAMPAL REMODELING AND IMPROVED MEMORY ENCODING IN PAEDIATRIC BRAIN TUMOR SURVIVORS TREATED WITH CRANIAL RADIATION: A PILOT RANDOMIZED CONTROLLED CROSSOVER STUDY

Neuro-Oncology / Jun 01, 2018

Ayoub, R., Miller, F., Beera, K., de Medeiros, C., Laughlin, S., Bouffet, E., & Mabbott, D. (2018). QOL-53. METFORMIN RESULTS IN HIPPOCAMPAL REMODELING AND IMPROVED MEMORY ENCODING IN PAEDIATRIC BRAIN TUMOR SURVIVORS TREATED WITH CRANIAL RADIATION: A PILOT RANDOMIZED CONTROLLED CROSSOVER STUDY. Neuro-Oncology, 20(suppl_2), i168–i168. https://doi.org/10.1093/neuonc/noy059.634

Behavioral evidence for two distinct memory systems in rats

Animal Cognition / Jun 22, 2022

Miller, N., Ayoub, R., Sentinathan, G., & Mallet, P. E. (2022). Behavioral evidence for two distinct memory systems in rats. Animal Cognition, 25(6), 1599–1608. https://doi.org/10.1007/s10071-022-01645-1

Failure of human rhombic lip differentiation underlies medulloblastoma formation

Nature / Sep 21, 2022

Hendrikse, L. D., Haldipur, P., Saulnier, O., Millman, J., Sjoboen, A. H., Erickson, A. W., Ong, W., Gordon, V., Coudière-Morrison, L., Mercier, A. L., Shokouhian, M., Suárez, R. A., Ly, M., Borlase, S., Scott, D. S., Vladoiu, M. C., Farooq, H., Sirbu, O., Nakashima, T., … Taylor, M. D. (2022). Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature, 609(7929), 1021–1028. https://doi.org/10.1038/s41586-022-05215-w

Research Interests

neuro-oncology

mouse imaging

cancer therapy

normal tissue toxicity

General Biochemistry, Genetics and Molecular Biology

General Medicine

Multidisciplinary

Animal Science and Zoology

Ecology, Evolution, Behavior and Systematics

Radiology, Nuclear Medicine and imaging

Radiation

Biophysics

Cancer Research

Neurology (clinical)

Oncology

Experimental and Cognitive Psychology

Join Ramy on NotedSource!

At NotedSource, we believe that professors, post-docs, scientists and other researchers have deep, untapped knowledge and expertise that can be leveraged to drive innovation within companies. NotedSource is committed to bridging the gap between academia and industry by providing a platform for collaboration with industry and networking with other researchers.

For industry, NotedSource identifies the right academic experts in 24 hours to help organizations build and grow. With a platform of thousands of knowledgeable PhDs, scientists, and industry experts, NotedSource makes connecting and collaborating easy.

For academic researchers such as professors, post-docs, and Ph.D.s, NotedSource provides tools to discover and connect to your colleagues with messaging and news feeds, in addition to the opportunity to be paid for your collaboration with vetted partners.