THANGASAMY SAMINATHAN

I have mix of expertise in Molecular Biology, Mapping and Functional Genomics, and Groundwater Remediation

Research Interests

Genetics
molecular biology
genomics and groundwater remediation
Biotechnology
Plant Science
Physiology
Genetics (clinical)
Cell Biology
Environmental Chemistry
Horticulture
Environmental Engineering
Pollution
Health, Toxicology and Mutagenesis
Waste Management and Disposal
Ecology
Ecology, Evolution, Behavior and Systematics
Nature and Landscape Conservation
Ecological Modeling
Agronomy and Crop Science

About

Dr. Thangasamy Saminathan is a highly educated and experienced scientist with a passion for biotechnology and agriculture. He completed his PhD in Biotechnology at the prestigious Taiwan International Graduate Program at Academia Sinica in 2011. He has a diverse range of experience in the field of biotechnology and agriculture. He works as an Environmental Resource Analyst at the West Virginia Department of Environmental Protection, where he utilized his knowledge and skills to analyze and assess environmental resources. He also serves as an Associate Adjunct Faculty at West Virginia State University, teaching biotechnology and agriculture courses to students. His research experience includes a postdoctoral position at Academia Sinica, where he worked on projects related to plant biotechnology and genetics. He gained hands-on experience in plant breeding and genetics. Dr. Saminathan's education and experience have equipped him with a strong foundation in biotechnology and agriculture, and he continues to be actively involved in research and teaching in these fields. He is a dedicated scientist who is committed to finding innovative solutions to challenges in agriculture and utilizing biotechnology for sustainable development.

Publications

Single nucleotide polymorphisms generated by genotyping by sequencing to characterize genome-wide diversity, linkage disequilibrium, and selective sweeps in cultivated watermelon

BMC Genomics / Sep 08, 2014

Nimmakayala, P., Levi, A., Abburi, L., Abburi, V. L., Tomason, Y. R., Saminathan, T., Vajja, V. G., Malkaram, S., Reddy, R., Wehner, T. C., Mitchell, S. E., & Reddy, U. K. (2014). Single nucleotide polymorphisms generated by genotyping by sequencing to characterize genome-wide diversity, linkage disequilibrium, and selective sweeps in cultivated watermelon. BMC Genomics, 15(1). https://doi.org/10.1186/1471-2164-15-767

Rice SIZ1, a SUMO E3 ligase, controls spikelet fertility through regulation of anther dehiscence

New Phytologist / Nov 16, 2010

Thangasamy, S., Guo, C., Chuang, M., Lai, M., Chen, J., & Jauh, G. (2010). Rice SIZ1, a SUMO E3 ligase, controls spikelet fertility through regulation of anther dehiscence. New Phytologist, 189(3), 869–882. Portico. https://doi.org/10.1111/j.1469-8137.2010.03538.x

Metagenomic and Metatranscriptomic Analyses of Diverse Watermelon Cultivars Reveal the Role of Fruit Associated Microbiome in Carbohydrate Metabolism and Ripening of Mature Fruits

Frontiers in Plant Science / Jan 19, 2018

Saminathan, T., García, M., Ghimire, B., Lopez, C., Bodunrin, A., Nimmakayala, P., Abburi, V. L., Levi, A., Balagurusamy, N., & Reddy, U. K. (2018). Metagenomic and Metatranscriptomic Analyses of Diverse Watermelon Cultivars Reveal the Role of Fruit Associated Microbiome in Carbohydrate Metabolism and Ripening of Mature Fruits. Frontiers in Plant Science, 9. https://doi.org/10.3389/fpls.2018.00004

Genome-wide identification of microRNAs in pomegranate (Punica granatum L.) by high-throughput sequencing

BMC Plant Biology / May 26, 2016

Saminathan, T., Bodunrin, A., Singh, N. V., Devarajan, R., Nimmakayala, P., Jeff, M., Aradhya, M., & Reddy, U. K. (2016). Genome-wide identification of microRNAs in pomegranate (Punica granatum L.) by high-throughput sequencing. BMC Plant Biology, 16(1). https://doi.org/10.1186/s12870-016-0807-3

Genome-wide Diversity and Association Mapping for Capsaicinoids and Fruit Weight in Capsicum annuum L

Scientific Reports / Nov 30, 2016

Nimmakayala, P., Abburi, V. L., Saminathan, T., Alaparthi, S. B., Almeida, A., Davenport, B., Nadimi, M., Davidson, J., Tonapi, K., Yadav, L., Malkaram, S., Vajja, G., Hankins, G., Harris, R., Park, M., Choi, D., Stommel, J., & Reddy, U. K. (2016). Genome-wide Diversity and Association Mapping for Capsaicinoids and Fruit Weight in Capsicum annuum L. Scientific Reports, 6(1). https://doi.org/10.1038/srep38081

Differential gene expression and alternative splicing between diploid and tetraploid watermelon

Journal of Experimental Botany / Dec 17, 2014

Saminathan, T., Nimmakayala, P., Manohar, S., Malkaram, S., Almeida, A., Cantrell, R., Tomason, Y., Abburi, L., Rahman, M. A., Vajja, V. G., Khachane, A., Kumar, B., Rajasimha, H. K., Levi, A., Wehner, T., & Reddy, U. K. (2014). Differential gene expression and alternative splicing between diploid and tetraploid watermelon. Journal of Experimental Botany, 66(5), 1369–1385. https://doi.org/10.1093/jxb/eru486

Genetic diversity and association mapping of bacterial blight and other horticulturally important traits with microsatellite markers in pomegranate from India

Molecular Genetics and Genomics / Feb 13, 2015

Singh, N. V., Abburi, V. L., Ramajayam, D., Kumar, R., Chandra, R., Sharma, K. K., Sharma, J., Babu, K. D., Pal, R. K., Mundewadikar, D. M., Saminathan, T., Cantrell, R., Nimmakayala, P., & Reddy, U. K. (2015). Genetic diversity and association mapping of bacterial blight and other horticulturally important traits with microsatellite markers in pomegranate from India. Molecular Genetics and Genomics, 290(4), 1393–1402. https://doi.org/10.1007/s00438-015-1003-0

Genome-Wide Differentiation of Various Melon Horticultural Groups for Use in GWAS for Fruit Firmness and Construction of a High Resolution Genetic Map

Frontiers in Plant Science / Sep 22, 2016

Nimmakayala, P., Tomason, Y. R., Abburi, V. L., Alvarado, A., Saminathan, T., Vajja, V. G., Salazar, G., Panicker, G. K., Levi, A., Wechter, W. P., McCreight, J. D., Korol, A. B., Ronin, Y., Garcia-Mas, J., & Reddy, U. K. (2016). Genome-Wide Differentiation of Various Melon Horticultural Groups for Use in GWAS for Fruit Firmness and Construction of a High Resolution Genetic Map. Frontiers in Plant Science, 7. https://doi.org/10.3389/fpls.2016.01437

High-Resolution Genetic Map for Understanding the Effect of Genome-Wide Recombination Rate on Nucleotide Diversity in Watermelon

G3 Genes|Genomes|Genetics / Nov 01, 2014

Reddy, U. K., Nimmakayala, P., Levi, A., Abburi, V. L., Saminathan, T., Tomason, Y. R., Vajja, G., Reddy, R., Abburi, L., Wehner, T. C., Ronin, Y., & Karol, A. (2014). High-Resolution Genetic Map for Understanding the Effect of Genome-Wide Recombination Rate on Nucleotide Diversity in Watermelon. G3 Genes|Genomes|Genetics, 4(11), 2219–2230. https://doi.org/10.1534/g3.114.012815

Genome-wide identification and gene expression pattern of ABC transporter gene family in Capsicum spp.

PLOS ONE / Apr 30, 2019

Lopez-Ortiz, C., Dutta, S. K., Natarajan, P., Peña-Garcia, Y., Abburi, V., Saminathan, T., Nimmakayala, P., & Reddy, U. K. (2019). Genome-wide identification and gene expression pattern of ABC transporter gene family in Capsicum spp. PLOS ONE, 14(4), e0215901. https://doi.org/10.1371/journal.pone.0215901

A Genome-Wide Scan of Selective Sweeps and Association Mapping of Fruit Traits Using Microsatellite Markers in Watermelon

Journal of Heredity / Nov 25, 2014

Reddy, U. K., Abburi, L., Abburi, V. L., Saminathan, T., Cantrell, R., Vajja, V. G., Reddy, R., Tomason, Y. R., Levi, A., Wehner, T. C., & Nimmakayala, P. (2014). A Genome-Wide Scan of Selective Sweeps and Association Mapping of Fruit Traits Using Microsatellite Markers in Watermelon. Journal of Heredity, 106(2), 166–176. https://doi.org/10.1093/jhered/esu077

Rice LGD1 containing RNA binding activity affects growth and development through alternative promoters

The Plant Journal / May 25, 2012

Thangasamy, S., Chen, P., Lai, M., Chen, J., & Jauh, G. (2012). Rice LGD1 containing RNA binding activity affects growth and development through alternative promoters. The Plant Journal, 71(2), 288–302. Portico. https://doi.org/10.1111/j.1365-313x.2012.04989.x

Genome-Wide Divergence and Linkage Disequilibrium Analyses for Capsicum baccatum Revealed by Genome-Anchored Single Nucleotide Polymorphisms

Frontiers in Plant Science / Nov 03, 2016

Nimmakayala, P., Abburi, V. L., Saminathan, T., Almeida, A., Davenport, B., Davidson, J., Reddy, C. V. C. M., Hankins, G., Ebert, A., Choi, D., Stommel, J., & Reddy, U. K. (2016). Genome-Wide Divergence and Linkage Disequilibrium Analyses for Capsicum baccatum Revealed by Genome-Anchored Single Nucleotide Polymorphisms. Frontiers in Plant Science, 7. https://doi.org/10.3389/fpls.2016.01646

Elevated carbon dioxide and drought modulate physiology and storage-root development in sweet potato by regulating microRNAs

Functional & Integrative Genomics / Sep 22, 2018

Saminathan, T., Alvarado, A., Lopez, C., Shinde, S., Gajanayake, B., Abburi, V. L., Vajja, V. G., Jagadeeswaran, G., Raja Reddy, K., Nimmakayala, P., & Reddy, U. K. (2018). Elevated carbon dioxide and drought modulate physiology and storage-root development in sweet potato by regulating microRNAs. Functional & Integrative Genomics, 19(1), 171–190. https://doi.org/10.1007/s10142-018-0635-7

Transcriptome Analysis of Invasive Plants in Response to Mineral Toxicity of Reclaimed Coal-Mine Soil in the Appalachian Region

Environmental Science & Technology / Aug 13, 2015

Saminathan, T., Malkaram, S. A., Patel, D., Taylor, K., Hass, A., Nimmakayala, P., Huber, D. H., & Reddy, U. K. (2015). Transcriptome Analysis of Invasive Plants in Response to Mineral Toxicity of Reclaimed Coal-Mine Soil in the Appalachian Region. Environmental Science & Technology, 49(17), 10320–10329. https://doi.org/10.1021/acs.est.5b01901

Punctured-hypocotyl method for high-efficient transformation and adventitious shoot regeneration of tomato

Scientia Horticulturae / Jan 01, 2014

Sivankalyani, V., Takumi, S., Thangasamy, S., Ashakiran, K., & Girija, S. (2014). Punctured-hypocotyl method for high-efficient transformation and adventitious shoot regeneration of tomato. Scientia Horticulturae, 165, 357–364. https://doi.org/10.1016/j.scienta.2013.11.034

Arsenic Stress-Related F-Box (ASRF) gene regulates arsenic stress tolerance in Arabidopsis thaliana

Journal of Hazardous Materials / Apr 01, 2021

Peña-Garcia, Y., Shinde, S., Natarajan, P., Lopez-Ortiz, C., Balagurusamy, N., Chavez, A. C. D., Saminathan, T., Nimmakayala, P., & Reddy, U. K. (2021). Arsenic Stress-Related F-Box (ASRF) gene regulates arsenic stress tolerance in Arabidopsis thaliana. Journal of Hazardous Materials, 407, 124831. https://doi.org/10.1016/j.jhazmat.2020.124831

Genome-wide divergence, haplotype distribution and population demographic histories for Gossypium hirsutum and Gossypium barbadense as revealed by genome-anchored SNPs

Scientific Reports / Jan 27, 2017

Reddy, U. K., Nimmakayala, P., Abburi, V. L., Reddy, C. V. C. M., Saminathan, T., Percy, R. G., Yu, J. Z., Frelichowski, J., Udall, J. A., Page, J. T., Zhang, D., Shehzad, T., & Paterson, A. H. (2017). Genome-wide divergence, haplotype distribution and population demographic histories for Gossypium hirsutum and Gossypium barbadense as revealed by genome-anchored SNPs. Scientific Reports, 7(1). https://doi.org/10.1038/srep41285

Impacts of genetic enhancement in pearl millet.

Crop variety improvement and its effect on productivity: the impact of international agricultural research / Jan 01, 2003

Bantilan, M. C. S., & Deb, U. K. (2003). Impacts of genetic enhancement in pearl millet. In Crop variety improvement and its effect on productivity: the impact of international agricultural research (pp. 215–240). CABI Publishing. https://doi.org/10.1079/9780851995496.0215

Comparative Genomics of the Cucurbitaceae

Genetics and Genomics of Cucurbitaceae / Jan 01, 2017

Nimmakayala, P., Saminathan, T., Abburi, V. L., Yadav, L. K., Tomason, Y., Levi, A., Weng, Y., & Reddy, U. K. (2017). Comparative Genomics of the Cucurbitaceae. In Plant Genetics and Genomics: Crops and Models (pp. 229–240). Springer International Publishing. https://doi.org/10.1007/7397_2017_2

Genome-Wide Association Study of Natural Variation in Arabidopsis Exposed to Acid Mine Drainage Toxicity and Validation of Associated Genes with Reverse Genetics

Plants / Jan 20, 2021

Ghimire, B., Saminathan, T., Bodunrin, A., Abburi, V. L., Kshetry, A. O., Shinde, S., Nimmakayala, P., & Reddy, U. K. (2021). Genome-Wide Association Study of Natural Variation in Arabidopsis Exposed to Acid Mine Drainage Toxicity and Validation of Associated Genes with Reverse Genetics. Plants, 10(2), 191. https://doi.org/10.3390/plants10020191

RNA isolation from high polyphenol containing tissues of pomegranate

Indian Journal of Horticulture / Jan 01, 2015

Singh, N. V., Saminathan, T., Chandra, R., Awachare, C., Babu, K. D., Mundewadikar, D. M., & Pal, R. K. (2015). RNA isolation from high polyphenol containing tissues of pomegranate. Indian Journal of Horticulture, 72(2), 273. https://doi.org/10.5958/0974-0112.2015.00051.1

Transcriptome Analysis of Cambium Tissue of Paulownia Collected during Winter and Spring

Diversity / Sep 01, 2021

Perry, Z. D., Saminathan, T., Arun, A., Vaidya, B. N., Basu, C., Reddy, U. K., & Joshee, N. (2021). Transcriptome Analysis of Cambium Tissue of Paulownia Collected during Winter and Spring. Diversity, 13(9), 423. https://doi.org/10.3390/d13090423

The Potential Health Benefits of Brown Rice

Sustainable Rice Production - Challenges, Strategies and Opportunities / Oct 04, 2023

Watanabe, S. (2023). The Potential Health Benefits of Brown Rice. In Sustainable Rice Production - Challenges, Strategies and Opportunities. IntechOpen. https://doi.org/10.5772/intechopen.107543

Stress responses and comparative transcriptome analysis of Arabidopsis thaliana ecotypes exposed to BTEX compounds

Environmental and Experimental Botany / Sep 01, 2022

Pacheco-Valenciana, A., Lopez-Ortiz, C., Natarajan, P., Saminathan, T., Nimmakayala, P., & Reddy, U. K. (2022). Stress responses and comparative transcriptome analysis of Arabidopsis thaliana ecotypes exposed to BTEX compounds. Environmental and Experimental Botany, 201, 104953. https://doi.org/10.1016/j.envexpbot.2022.104953

The ankyrin repeat gene family in Capsicum spp: Genome-wide survey, characterization and gene expression profile

Scientific Reports / Mar 04, 2020

Lopez-Ortiz, C., Peña-Garcia, Y., Natarajan, P., Bhandari, M., Abburi, V., Dutta, S. K., Yadav, L., Stommel, J., Nimmakayala, P., & Reddy, U. K. (2020). The ankyrin repeat gene family in Capsicum spp: Genome-wide survey, characterization and gene expression profile. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-61057-4

Northwestern Blot of Protein-RNA Interaction from Young Rice Panicles

BIO-PROTOCOL / Jan 01, 2013

Thangasamy, S., & Jauh, G.-Y. (2013). Northwestern Blot of Protein-RNA Interaction from Young Rice Panicles. BIO-PROTOCOL, 3(7). https://doi.org/10.21769/bioprotoc.625

Apomixis in Crop Plants—Cytogenetic Basis and Role in Plant Breeding

Chromosome Engineering in Plants: Genetics, Breeding, Evolution, Part A / Jan 01, 1991

HANNA, W. W. (1991). Apomixis in Crop Plants—Cytogenetic Basis and Role in Plant Breeding. In Developments in Plant Genetics and Breeding (pp. 229–242). Elsevier. https://doi.org/10.1016/b978-0-444-88259-2.50015-1

Breeding behaviour for juice quality through selfing and progeny evaluation in hybrid clones and inbred derivatives of sugarcane (Saccharum sp.)

Sugar Tech / Sep 01, 2003

Hemaprabha, G., Natarajan, U. S., & Balasundaram, N. (2003). Breeding behaviour for juice quality through selfing and progeny evaluation in hybrid clones and inbred derivatives of sugarcane (Saccharum sp.). Sugar Tech, 5(3), 177–180. https://doi.org/10.1007/bf02943631

Education

Academia Sinica

PhD Biotechnology, Taiwan International Graduate Program / January, 2011

Taipei

Tamil Nadu Agricultural University

MSc Agriculture (Plant Breeding and Genetics), Center for Plant Breeding and Genetics / August, 2000

Coimbatore

Tamil Nadu Agricultural University

BSc Agriculture, Anbil Dharmalingam Agricultural College and Research Institute / November, 1996

Coimbatore

Experience

West Virginia Department of Environmental Protection

Environmental Resource Analyst / February, 2018Present

West Virginia State University

Associate Adjunct Faculty / May, 2013Present

Academia Sinica

Postdoctoral Research Fellow / February, 2011April, 2013

Tamil Nadu Agricultural University

Senior Research Fellow / March, 2003August, 2004

Sugarcane Breeding Institute (ICAR)

Research Associate / October, 2000February, 2003

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