Work with thought leaders and academic experts in hepatology
Companies can greatly benefit from collaborating with an academic researcher specializing in hepatology. Here are a few reasons why:
Researchers on NotedSource with backgrounds in hepatology include Dr. Shilpa Patil, Ph.D, Mounika Gudeppu, Luke Connelly, Roshonda Jones, Giuliana Noratto, James Boot, PhD, Dana Walsh, Ph.D., Marina Baretti, Leo R Fitzpatrick PhD, Elham Shirvani-Dastgerdi, Emma Hernandez-Sanabria, and Pranshu Sahgal, Ph.D..
Dr. Shilpa Patil, Ph.D
PhD & Postdoc level expertise in Cancer Research
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Most Relevant Publications (4+)
20 total publications
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming
Cellular and Molecular Gastroenterology and Hepatology / Jan 01, 2023
Zhang, Z., Wang, X., Hamdan, F. H., Likhobabina, A., Patil, S., Aperdannier, L., Sen, M., Traub, J., Neesse, A., Fischer, A., Papantonis, A., Singh, S. K., Ellenrieder, V., Johnsen, S. A., & Hessmann, E. (2023). NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming. Cellular and Molecular Gastroenterology and Hepatology, 15(5), 1219–1246. https://doi.org/10.1016/j.jcmgh.2023.01.015
EZH2 controls PDAC plasticity by regulating differentiation genes
Pancreatology / Jun 01, 2019
Patil, S., Najafova, Z., Kari, V., Wang, X., Bohnenberger, H., Kopp, W., Spitalieri, J., Neesse, A., Ellenrieder, V., Johnsen, S., & Hessmann, E. (2019). EZH2 controls PDAC plasticity by regulating differentiation genes. Pancreatology, 19, S11. https://doi.org/10.1016/j.pan.2019.05.021
Impact of cytosolic 5'-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer
Pancreatology / Jun 01, 2018
Patzak, M. S., Hessmann, E., Kari, V., Kitz, J., Patil, S., Richards, F. M., Jodrell, D. I., Johnsen, S. A., Ellenrieder, V., & Neesse, A. (2018). Impact of cytosolic 5’-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer. Pancreatology, 18(4), S91. https://doi.org/10.1016/j.pan.2018.05.247
Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity
Pancreatology / Jul 01, 2017
Patil, S., Witte, H., Neesse, A., Johnsen, S., Ellenrieder, V., & Hessmann, E. (2017). Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity. Pancreatology, 17(3), S41. https://doi.org/10.1016/j.pan.2017.05.128
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Mounika Gudeppu
Ph.D. holder in Pharmacology and Toxicology, holded an SME position in HCL Tech Medical device Biocompatibility domain
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Other Research Interests (12)
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Most Relevant Publications (1+)
17 total publications
The Successful Use of N-Acetyl-cysteine to Treat Sorafenib-Induced Hepatotoxicity
American Journal of Gastroenterology / Oct 01, 2017
Hasan, M., Alukal, J., Tarsitano, J., & Choi, E. (2017). The Successful Use of N-Acetyl-cysteine to Treat Sorafenib-Induced Hepatotoxicity: 2261. American Journal of Gastroenterology, 112, S1243. https://doi.org/10.14309/00000434-201710001-02262
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Luke Connelly
Professor of Health Economics, The University of Queensland, CBEH
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Other Research Interests (42)
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Most Relevant Publications (1+)
105 total publications
Economic evaluation of fecal microbiota transplantation for the treatment of recurrentClostridium difficileinfection in Australia
Journal of Gastroenterology and Hepatology / Nov 29, 2016
Merlo, G., Graves, N., Brain, D., & Connelly, L. B. (2016). Economic evaluation of fecal microbiota transplantation for the treatment of recurrentClostridium difficileinfection in Australia. Journal of Gastroenterology and Hepatology, 31(12), 1927–1932. Portico. https://doi.org/10.1111/jgh.13402
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Roshonda Jones
Bioinformatics research scientist using computational and statistical techniques to examine the relationship between diet, health and microbes
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Other Research Interests (23)
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Most Relevant Publications (1+)
43 total publications
Sa1801 Local Environmental Conditions Override NOD2-Mediated Regulatory Effects on Mouse Intestinal Microbial Composition
Gastroenterology / May 01, 2013
Carroll, I. M., Shanahan, M. T., Barner, R., Fodor, A. A., Sartor, R. B., & Gulati, A. S. (2013). Sa1801 Local Environmental Conditions Override NOD2-Mediated Regulatory Effects on Mouse Intestinal Microbial Composition. Gastroenterology, 144(5), S-309. https://doi.org/10.1016/s0016-5085(13)61112-9
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James Boot, PhD
Bioinformatician at Queen Mary University of London, experienced in a wide variety of data analysis pipelines.
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Other Research Interests (0)
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Most Relevant Publications (1+)
3 total publications
Toll-like receptor 5 signalling mediates pro-inflammatory and fibrogenic responses in non-alcoholic steatohepatitis (NASH)
Journal of Hepatology / Jun 01, 2023
Li, W., Garrido, P., Mir, I. G., Waller, K., Jong, A. V., Brindley, J. H., Khan, W., Hood, G., Boot, J., Mein, C., Devalia, K., Loy, J., & Alazawi, W. (2023). Toll-like receptor 5 signalling mediates pro-inflammatory and fibrogenic responses in non-alcoholic steatohepatitis (NASH). Journal of Hepatology, 78, S740. https://doi.org/10.1016/s0168-8278(23)02141-4
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Dana Walsh, Ph.D.
Senior Microbiome Scientist at CosmosID
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Other Research Interests (10)
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Most Relevant Publications (1+)
17 total publications
Mo1931 FAILURE IS NOT FINAL: CLINICAL RESPONSE AND MICROBIOME RESTORATION BY INVESTIGATIONAL DRUG RBX2660 ARE NOT COMPROMISED FOLLOWING PREVIOUS NON-RESPONSE FOR PREVENTING CLOSTRIDIOIDES DIFFICILE RECURRENCE
Gastroenterology / May 01, 2020
Steiner, T. S., Walsh, D. M., Gonzalez, C., Shannon, B., Su, X., & Blount, K. (2020). Mo1931 FAILURE IS NOT FINAL: CLINICAL RESPONSE AND MICROBIOME RESTORATION BY INVESTIGATIONAL DRUG RBX2660 ARE NOT COMPROMISED FOLLOWING PREVIOUS NON-RESPONSE FOR PREVENTING CLOSTRIDIOIDES DIFFICILE RECURRENCE. Gastroenterology, 158(6), S-982. https://doi.org/10.1016/s0016-5085(20)33128-0
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Marina Baretti
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
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Other Research Interests (14)
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Most Relevant Publications (4+)
57 total publications
Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer
Digestive and Liver Disease / Oct 01, 2015
Sefrioui, D., Sarafan-Vasseur, N., Beaussire, L., Baretti, M., Gangloff, A., Blanchard, F., Clatot, F., Sabourin, J.-C., Sesboüé, R., Frebourg, T., Michel, P., & Di Fiore, F. (2015). Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer. Digestive and Liver Disease, 47(10), 884–890. https://doi.org/10.1016/j.dld.2015.05.023
Prognostic Implications of the Immune Tumor Microenvironment in Patients With Pancreatic and Gastrointestinal Neuroendocrine Tumors
Pancreas / May 01, 2021
Baretti, M., Zhu, Q., Zahurak, M., Bhaijee, F., Xu, H., Engle, E. L., Kotte, A., Pawlik, T. M., Anders, R. A., & De Jesus-Acosta, A. (2021). Prognostic Implications of the Immune Tumor Microenvironment in Patients With Pancreatic and Gastrointestinal Neuroendocrine Tumors. Pancreas, 50(5), 719–726. https://doi.org/10.1097/mpa.0000000000001831
Surgical Debulking for Refractory Hyperammonemic Encephalopathy in Fibrolamellar Hepatocellular Carcinoma
Hepatology / Aug 21, 2021
Solipuram, V., Baretti, M., Kim, A. Y., Chen, L. X., Fahrner, J. A., Gunay‐Aygun, M., Peng, X. P., Hardenbergh, D., Ferguson, A., Griffith, P., Wang, Y., Brancati, M., Gopalakrishna, H., Kato, T., Shubert, C., Laheru, D., & Yarchoan, M. (2021). Surgical Debulking for Refractory Hyperammonemic Encephalopathy in Fibrolamellar Hepatocellular Carcinoma. Hepatology, 74(5), 2899–2901. https://doi.org/10.1002/hep.31998
The Significance of Ascites in Patients With Pancreatic Ductal Adenocarcinoma
Pancreas / Apr 01, 2019
Baretti, M., Pulluri, B., Tsai, H.-L., Blackford, A. L., Wolfgang, C. L., Laheru, D., Zheng, L., Herman, J., Le, D. T., Narang, A. K., & de Jesus-Acosta, A. (2019). The Significance of Ascites in Patients With Pancreatic Ductal Adenocarcinoma. Pancreas, 48(4), 585–589. https://doi.org/10.1097/mpa.0000000000001262
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Leo R Fitzpatrick PhD
GI Pharmacology and IBD Research Consultant
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Other Research Interests (32)
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Most Relevant Publications (28+)
89 total publications
CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats
Gastroenterology / Apr 01, 2001
FITZPATRICK, L., WANG, J., & LE, T. (2001). CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats. Gastroenterology, 120(5), A685–A685. https://doi.org/10.1016/s0016-5085(01)83409-0
CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats
Gastroenterology / Apr 01, 2001
Fitzpatrick, L. R., Wang, J., & Le, T. (2001). CAPE, an inhibitor of nuclear factor-kappa B (NF-κB), attenuates bacterial peptidoglycan polysaccharide (PG-PS) induced colitis in rats. Gastroenterology, 120(5), A685. https://doi.org/10.1016/s0016-5085(08)83409-9
Effect of epidermal growth factor on polyamine-synthesizing enzymes in rat enterocytes
American Journal of Physiology-Gastrointestinal and Liver Physiology / Feb 01, 1987
Fitzpatrick, L. R., Wang, P., & Johnson, L. R. (1987). Effect of epidermal growth factor on polyamine-synthesizing enzymes in rat enterocytes. American Journal of Physiology-Gastrointestinal and Liver Physiology, 252(2), G209–G214. https://doi.org/10.1152/ajpgi.1987.252.2.g209
Effect of refeeding on polyamine biosynthesis in isolated enterocytes
American Journal of Physiology-Gastrointestinal and Liver Physiology / May 01, 1986
Fitzpatrick, L. R., Wang, P., Eikenburg, B. E., Haddox, M. K., & Johnson, L. R. (1986). Effect of refeeding on polyamine biosynthesis in isolated enterocytes. American Journal of Physiology-Gastrointestinal and Liver Physiology, 250(5), G709–G713. https://doi.org/10.1152/ajpgi.1986.250.5.g709
Relationship between ornithine decarboxylase activity and gastric damage
American Journal of Physiology-Gastrointestinal and Liver Physiology / Dec 01, 1987
Thirumalai, C. H., Tseng, C. C., Tabata, K., Fitzpatrick, L. R., & Johnson, L. R. (1987). Relationship between ornithine decarboxylase activity and gastric damage. American Journal of Physiology-Gastrointestinal and Liver Physiology, 253(1), G1–G6. https://doi.org/10.1152/ajpgi.1987.253.1.g1
T2035 The Novel Probiotic Escherichia coli Strain M-17 Uniquely Inhibits Pro-Inflammatory Cytokine Secretion in Macrophage and Colonic Epithelial Cell Lines
Gastroenterology / May 01, 2010
Fitzpatrick, L. R., Small, J. S., Bostwick, E. F., & Hoerr, R. A. (2010). T2035 The Novel Probiotic Escherichia coli Strain M-17 Uniquely Inhibits Pro-Inflammatory Cytokine Secretion in Macrophage and Colonic Epithelial Cell Lines. Gastroenterology, 138(5), S-618. https://doi.org/10.1016/s0016-5085(10)62848-x
Amiloride inhibits rat mucosal ornithine decarboxylase activity and DNA synthesis
American Journal of Physiology-Gastrointestinal and Liver Physiology / Mar 01, 1988
Ulrich-Baker, M. G., Wang, P., Fitzpatrick, L., & Johnson, L. R. (1988). Amiloride inhibits rat mucosal ornithine decarboxylase activity and DNA synthesis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 254(3), G408–G415. https://doi.org/10.1152/ajpgi.1988.254.3.g408
Indomethacin‐induced gastric antral damage in hamsters: are neutrophils involved?
Alimentary Pharmacology & Therapeutics / Feb 01, 1999
Fitzpatrick, Sakurai, & Le. (1999). Indomethacin‐induced gastric antral damage in hamsters: are neutrophils involved? Alimentary Pharmacology & Therapeutics, 13(2), 195–202. Portico. https://doi.org/10.1046/j.1365-2036.1999.00444.x
Inhibition of IL-17 Release by the Novel Anti-Inflammatory Drug Vidofludimus Involves Attenuation of STAT3 and NF-kappa B Signaling Pathways in Murine Splenocytes and Hapten-Induced Colitis
Gastroenterology / May 01, 2011
Fitzpatrick, L. R., Small, J. S., & Ammendola, A. (2011). Inhibition of IL-17 Release by the Novel Anti-Inflammatory Drug Vidofludimus Involves Attenuation of STAT3 and NF-kappa B Signaling Pathways in Murine Splenocytes and Hapten-Induced Colitis. Gastroenterology, 140(5), S-837. https://doi.org/10.1016/s0016-5085(11)63470-7
Effect of naproxen on the hamster gastric antrum: ulceration, adaptation and efficacy of anti‐ulcer drugs
Alimentary Pharmacology & Therapeutics / Nov 01, 1999
Fitzpatrick, Sakurai, & Le. (1999). Effect of naproxen on the hamster gastric antrum: ulceration, adaptation and efficacy of anti‐ulcer drugs. Alimentary Pharmacology & Therapeutics, 13(11), 1553–1562. Portico. https://doi.org/10.1046/j.1365-2036.1999.00624.x
M1658 A Novel Immunosuppressive Drug (4SC-101) Improves TNBS-Induced Colitis in Mice
Gastroenterology / May 01, 2009
Fitzpatrick, L. R., Small, J. S., Zhang, G., & Jankowsky, R. (2009). M1658 A Novel Immunosuppressive Drug (4SC-101) Improves TNBS-Induced Colitis in Mice. Gastroenterology, 136(5), A-404. https://doi.org/10.1016/s0016-5085(09)61857-6
The modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on OPC antioxidant
The American Journal of Gastroenterology / Sep 01, 2001
FARHADI, A. (2001). The modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on OPC antioxidant. The American Journal of Gastroenterology, 96(9), S290. https://doi.org/10.1016/s0002-9270(01)03699-1
Fos expression in the colonic myenteric plexus induced by water avoidance stress in different rat strains
Gastroenterology / Apr 01, 2001
MIAMPAMBA, M., MILLION, M., & TACHE, Y. (2001). Fos expression in the colonic myenteric plexus induced by water avoidance stress in different rat strains. Gastroenterology, 120(5), A715–A715. https://doi.org/10.1016/s0016-5085(01)83560-5
Tu1744 - Ex Vivo Effects of Ror-Gamma T Inhibitors on Proinflammatory Cytokine Secretion from Colonic Strips of Mice with DSS-Induced Colitis
Gastroenterology / May 01, 2018
Fitzpatrick, L. R., Talbott, G., Buhr, C. A., Alton, G., & Zapf, J. (2018). Tu1744 - Ex Vivo Effects of Ror-Gamma T Inhibitors on Proinflammatory Cytokine Secretion from Colonic Strips of Mice with DSS-Induced Colitis. Gastroenterology, 154(6), S-1007-S-1008. https://doi.org/10.1016/s0016-5085(18)33370-5
A Novel ROR-Gamma T Inhibitor (VPR-254) Attenuates Key Parameters of Innate Immune Colitis in Mice
Gastroenterology / Apr 01, 2017
Fitzpatrick, L. R., O’Connell, R., Talbott, G., Bendele, P., Alton, G., & Zapf, J. (2017). A Novel ROR-Gamma T Inhibitor (VPR-254) Attenuates Key Parameters of Innate Immune Colitis in Mice. Gastroenterology, 152(5), S30–S31. https://doi.org/10.1016/s0016-5085(17)30468-7
Sa1834 Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Macrophage and Colonic Epithelial Cell Lines
Gastroenterology / Apr 01, 2016
Fitzpatrick, L. R., Talbott, G., & Woldemariam, T. (2016). Sa1834 Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Macrophage and Colonic Epithelial Cell Lines. Gastroenterology, 150(4), S376–S377. https://doi.org/10.1016/s0016-5085(16)31323-3
90 Efficacy of a Novel Small Molecule RORgt Inverse Agonist in Mouse DSS and TNBS Models of Inflammatory Bowel Disease
Gastroenterology / Apr 01, 2015
Fitzpatrick, L. R., Zapf, J., Flood, E. M., Ravula, S. B., Lingardo, L. K., Small, J., Tucci, F., Buhr, C. A., & Alton, G. (2015). 90 Efficacy of a Novel Small Molecule RORgt Inverse Agonist in Mouse DSS and TNBS Models of Inflammatory Bowel Disease. Gastroenterology, 148(4), S-26. https://doi.org/10.1016/s0016-5085(15)30090-1
Sa2053 Bacillus Coagulans Bc30 Limits the Recurrence of Clostridium diJicile-Induced Colitis Following Vancomycin Withdrawal in Mice
Gastroenterology / May 01, 2012
Fitzpatrick, L. R., Small, J. S., Greene, W., Karpa, K., & Keller, D. (2012). Sa2053 Bacillus Coagulans Bc30 Limits the Recurrence of Clostridium diJicile-Induced Colitis Following Vancomycin Withdrawal in Mice. Gastroenterology, 142(5), S-390. https://doi.org/10.1016/s0016-5085(12)61479-6
M1651 Melanin-Concentrating Hormone Receptor 1 Antagonists Attenuate TNBS-Induced Colitis in Mice
Gastroenterology / May 01, 2009
Fitzpatrick, L. R., Small, J. S., & Zhang, G. (2009). M1651 Melanin-Concentrating Hormone Receptor 1 Antagonists Attenuate TNBS-Induced Colitis in Mice. Gastroenterology, 136(5), A-403. https://doi.org/10.1016/s0016-5085(09)61850-3
A comparison of sucralfate and bismuth subsalicylate formulations in rabbit esophageal models
Gastroenterology / Apr 01, 1995
A comparison of sucralfate and bismuth subsalicylate formulations in rabbit esophageal models. (1995). Gastroenterology, 108(4), A94. https://doi.org/10.1016/0016-5085(95)23040-8
Tu1617 The Synthetic Triterpenoid (CDDO-IM) Inhibits STAT3, As Well As IL-17, and Improves DSS-Induced Colitis in Mice
Gastroenterology / May 01, 2013
Stonesifer, E., Fitzpatrick, L. R., Small, J., & Liby, K. T. (2013). Tu1617 The Synthetic Triterpenoid (CDDO-IM) Inhibits STAT3, As Well As IL-17, and Improves DSS-Induced Colitis in Mice. Gastroenterology, 144(5), S-807. https://doi.org/10.1016/s0016-5085(13)62986-8
Bacillus Coagulans (Bc 30 ) Improves Some Indices of Clostridium difficile -Induced Colitis in Mice
Gastroenterology / May 01, 2011
Fitzpatrick, L. R., Small, J. S., Greene, W., Karpa, K., & Keller, D. (2011). Bacillus Coagulans (Bc 30 ) Improves Some Indices of Clostridium difficile -Induced Colitis in Mice. Gastroenterology, 140(5), S-849. https://doi.org/10.1016/s0016-5085(11)63523-3
Characterization of the reactivation phase of dextran sodium sulfate (DSS)-induced colitis in rats
Gastroenterology / Apr 01, 1998
Fitzpatrick, L. R., Williams, J., & Le. Maryland, T. (1998). Characterization of the reactivation phase of dextran sodium sulfate (DSS)-induced colitis in rats. Gastroenterology, 114, A976. https://doi.org/10.1016/s0016-5085(98)83975-9
Novel characterization and quantification of bismuth binding to gastric mucosa
Gastroenterology / Apr 01, 1995
Novel characterization and quantification of bismuth binding to gastric mucosa. (1995). Gastroenterology, 108(4), A180. https://doi.org/10.1016/0016-5085(95)23381-4
Regulation of intestinal ornithine decarboxylase (ODC) expression during postnatal development by ODC antizyme in rats
Gastroenterology / Apr 01, 2000
Lin, C.-H., Tolia, V. K., & Vijesurier, R. M. (2000). Regulation of intestinal ornithine decarboxylase (ODC) expression during postnatal development by ODC antizyme in rats. Gastroenterology, 118(4), A292. https://doi.org/10.1016/s0016-5085(00)83253-9
Ex Vivo Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Colonic Strips of Mice with Dssinduced Colitis
Gastroenterology / Apr 01, 2017
Fitzpatrick, L. R., Talbott, G., Mokrushin, E., & Woldemariam, T. (2017). Ex Vivo Effects of Silymarin Fractions on Pro-Inflammatory Cytokine Secretion from Colonic Strips of Mice with Dssinduced Colitis. Gastroenterology, 152(5), S571. https://doi.org/10.1016/s0016-5085(17)32067-x
Colitis Development in IL-10 Deficient Mice Reveals a Direct Role of MCH in Regulating IL-10 Expression by Monocytes
Gastroenterology / May 01, 2011
Ziogas, D., ElKhal, A., Najarian, R. M., Mustafa, S. N., Reizes, O., Fitzpatrick, L. R., & Kokkotou, E. (2011). Colitis Development in IL-10 Deficient Mice Reveals a Direct Role of MCH in Regulating IL-10 Expression by Monocytes. Gastroenterology, 140(5), S-518. https://doi.org/10.1016/s0016-5085(11)62150-1
S1743 Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Rats
Gastroenterology / Apr 01, 2008
Maines, L. W., Fitzpatrick, L. R., Green, C., & Smith, C. D. (2008). S1743 Efficacy of a Sphingosine Kinase Inhibitor in the Treatment of 2,4,6-Trinitrobenezenesulfonic Acid (TNBS)-Induced Colitis in Rats. Gastroenterology, 134(4), A-261. https://doi.org/10.1016/s0016-5085(08)61214-7
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Elham Shirvani-Dastgerdi
Enthusiastic scientist with 15+ years of research experience in Molecular biology and cell and gene therapy
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Most Relevant Publications (3+)
18 total publications
Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy
Journal of Hepatology / Aug 01, 2017
Shirvani-Dastgerdi, E., Winer, B. Y., Celià-Terrassa, T., Kang, Y., Tabernero, D., Yagmur, E., Rodríguez-Frías, F., Gregori, J., Luedde, T., Trautwein, C., Ploss, A., & Tacke, F. (2017). Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy. Journal of Hepatology, 67(2), 246–254. https://doi.org/10.1016/j.jhep.2017.03.027
Impact of Drug-Resistance Polymerase Mutations on the Replication of HBeAg-Positive and HBeAg-Negative Hepatitis B Virus Strains in Vitro
Hepatitis Monthly / Jun 01, 2012
Tacke, F., & Shirvani-Dastgerdi, E. (2012). Impact of Drug-Resistance Polymerase Mutations on the Replication of HBeAg-Positive and HBeAg-Negative Hepatitis B Virus Strains in Vitro. Hepatitis Monthly, 12(6), 357–360. https://doi.org/10.5812/hepatmon.6131
Hepatitis E Virus Infection in Macaca Mulatta
Hepatitis Monthly / Sep 30, 2011
Dastgerdi, E. S., & Amini-Bavil-Olyaee, S. (2011). Hepatitis E Virus Infection in Macaca Mulatta. Hepatitis Monthly, 11(10), 852–853. https://doi.org/10.5812/kowsar.1735143x.783
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Emma Hernandez-Sanabria
Microbiome Research & Strategy | Exploring data, delivering innovation | Industry collabs | Fermentation!
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53 total publications
In vitro ecology: a discovery engine for microbiome therapies
Nature Reviews Gastroenterology & Hepatology / Sep 15, 2020
Hernandez-Sanabria, E., Vázquez-Castellanos, J. F., & Raes, J. (2020). In vitro ecology: a discovery engine for microbiome therapies. Nature Reviews Gastroenterology & Hepatology, 17(12), 711–712. https://doi.org/10.1038/s41575-020-00364-7
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Pranshu Sahgal, Ph.D.
Cell and Molecular biologist in cancer biology
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20 total publications
An Enhancer-Driven Stem Cell–Like Program Mediated by SOX9 Blocks Intestinal Differentiation in Colorectal Cancer
Gastroenterology / Jan 01, 2022
Liang, X., Duronio, G. N., Yang, Y., Bala, P., Hebbar, P., Spisak, S., Sahgal, P., Singh, H., Zhang, Y., Xie, Y., Cejas, P., Long, H. W., Bass, A. J., & Sethi, N. S. (2022). An Enhancer-Driven Stem Cell–Like Program Mediated by SOX9 Blocks Intestinal Differentiation in Colorectal Cancer. Gastroenterology, 162(1), 209–222. https://doi.org/10.1053/j.gastro.2021.09.044
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Example hepatology projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on hepatology?
Drug Development and Clinical Trials
An academic researcher in hepatology can contribute to the development of new drugs and therapies for liver diseases. They can design and conduct clinical trials, analyze data, and provide valuable insights into the efficacy and safety of potential treatments.
Diagnostic Tools and Biomarkers
Collaborating with a hepatology expert can lead to the development of advanced diagnostic tools and biomarkers for liver diseases. These tools can improve early detection, prognosis, and personalized treatment strategies, ultimately benefiting patients and healthcare providers.
Genomic and Proteomic Research
Hepatology researchers can contribute to genomic and proteomic studies focused on understanding the molecular mechanisms underlying liver diseases. This knowledge can help identify novel therapeutic targets and biomarkers, paving the way for precision medicine approaches.
Liver Disease Epidemiology
Academic researchers in hepatology can collaborate with companies to conduct epidemiological studies on liver diseases. This research can provide valuable insights into disease prevalence, risk factors, and trends, enabling companies to develop targeted prevention and intervention strategies.
Healthcare Policy and Guidelines
Companies can benefit from the expertise of hepatology researchers in shaping healthcare policies and guidelines related to liver diseases. Their insights can contribute to the development of evidence-based practices, improved patient care, and better allocation of healthcare resources.