Work with academic experts in molecular medicine
A scholar or researcher with expertise in molecular medicine can help business and industrial clients solve their molecular medicine problems and conduct molecular medicine research to get ahead on R&D. Experts on NotedSource with backgrounds in molecular medicine include Aimee Eggler, Giuliana Noratto, Keisha Walters, Jeffrey Townsend, Dr. Sakshi Kabra Malpani, Jennifer Aaker, Katelyn Katelyn Masiuk, John Joe, and Marina Baretti.
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
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Other Research Interests (26)
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Most Relevant Publications (3+)
25 total publications
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding
Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013
Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112
Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease
Journal of Medicinal Chemistry / Jan 03, 2013
Jacobs, J., Grum-Tokars, V., Zhou, Y., Turlington, M., Saldanha, S. A., Chase, P., Eggler, A., Dawson, E. S., Baez-Santos, Y. M., Tomar, S., Mielech, A. M., Baker, S. C., Lindsley, C. W., Hodder, P., Mesecar, A., & Stauffer, S. R. (2013). Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. Journal of Medicinal Chemistry, 56(2), 534–546. https://doi.org/10.1021/jm301580n
Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds
Molecules / Apr 03, 2000
Peterson, C., Tsao, R., Eggler, A., & Coats, J. (2000). Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds. Molecules, 5(12), 648–654. https://doi.org/10.3390/50400648
Giuliana Noratto
Food Scientist PhD and Registered Dietician - Texas A&M University
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Other Research Interests (48)
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Most Relevant Publications (2+)
91 total publications
Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion
Molecules / Oct 25, 2022
Silveira Rabelo, A. C., Mertens-Talcott, S. U., Chew, B. P., & Noratto, G. (2022). Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion. Molecules, 27(21), 7245. https://doi.org/10.3390/molecules27217245
Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry / Nov 01, 2022
Rabelo, A. C. S., Miglino, M. A., Arbizu, S., Carreira, A. C. O., Filho, A. J. C., Carneiro, F. J. C., Layosa, M. A. A., & Noratto, G. (2022). Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry, 22(18), 3136–3147. https://doi.org/10.2174/1871520622666220608122154
Keisha Walters
I am the Conoco-Dupont Professor of Chemical, Biological and Materials Engineering at the University of Oklahoma (OU), and I have experience in industry (R&D, Milliken Chemical).
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Other Research Interests (46)
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Most Relevant Publications (1+)
49 total publications
Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa
Journal of Nanobiotechnology / Mar 17, 2016
Vasquez, E. S., Feugang, J. M., Willard, S. T., Ryan, P. L., & Walters, K. B. (2016). Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa. Journal of Nanobiotechnology, 14(1). https://doi.org/10.1186/s12951-016-0168-y
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
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Other Research Interests (78)
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Most Relevant Publications (6+)
207 total publications
The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity
The Journal of Molecular Diagnostics / Jan 01, 2022
Townsend, J. P., & Wells, C. R. (2022). The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity. The Journal of Molecular Diagnostics, 24(1), 101–103. https://doi.org/10.1016/j.jmoldx.2021.10.002
Cost-effectiveness of next-generation vaccines: The case of pertussis
Vaccine / Jun 01, 2016
Fitzpatrick, M. C., Wenzel, N. S., Scarpino, S. V., Althouse, B. M., Atkins, K. E., Galvani, A. P., & Townsend, J. P. (2016). Cost-effectiveness of next-generation vaccines: The case of pertussis. Vaccine, 34(29), 3405–3411. https://doi.org/10.1016/j.vaccine.2016.04.010
Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US
Vaccine / Jan 01, 2016
Alfaro-Murillo, J. A., Townsend, J. P., & Galvani, A. P. (2016). Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US. Vaccine, 34(2), 225–229. https://doi.org/10.1016/j.vaccine.2015.11.039
Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty
Vaccine / Jun 01, 2013
Ndeffo Mbah, M. L., Medlock, J., Meyers, L. A., Galvani, A. P., & Townsend, J. P. (2013). Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty. Vaccine, 31(30), 3079–3089. https://doi.org/10.1016/j.vaccine.2013.04.052
Monitoring and modeling horizontal gene transfer
Nature Biotechnology / Aug 31, 2004
Nielsen, K. M., & Townsend, J. P. (2004). Monitoring and modeling horizontal gene transfer. Nature Biotechnology, 22(9), 1110–1114. https://doi.org/10.1038/nbt1006
Monitoring horizontal gene transfer
Nature Biotechnology / Nov 01, 2004
Davison, J. (2004). Monitoring horizontal gene transfer. Nature Biotechnology, 22(11), 1349–1349. https://doi.org/10.1038/nbt1104-1349a
Jennifer Aaker
General Atlantic Professor, Stanford University
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Most Relevant Publications (1+)
79 total publications
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG
Advances in Enzyme Regulation / Jan 01, 2002
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG. (2002). Advances in Enzyme Regulation, 42, EX17. https://doi.org/10.1016/s0065-2571(01)00055-3
Katelyn Katelyn Masiuk
Co-Founder and CSO at Immunovec
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Other Research Interests (23)
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Most Relevant Publications (6+)
13 total publications
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates
Molecular Therapy / Aug 01, 2019
Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome
Cell Stem Cell / Feb 01, 2019
Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003
PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector
Molecular Therapy - Methods & Clinical Development / Jun 01, 2019
Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods & Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005
Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells
Molecular Therapy / Sep 01, 2017
Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023
Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy
Stem Cells / Apr 23, 2015
Baldwin, K., Urbinati, F., Romero, Z., Campo-Fernandez, B., Kaufman, M. L., Cooper, A. R., Masiuk, K., Hollis, R. P., & Kohn, D. B. (2015). Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy. Stem Cells, 33(5), 1532–1542. https://doi.org/10.1002/stem.1957
Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study
Human Gene Therapy / Oct 01, 2018
Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061
John Joe
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
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Other Research Interests (73)
Most Relevant Publications (2+)
95 total publications
13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis
Chemistry & Biology / Aug 01, 2013
Beste, D. J. V., Nöh, K., Niedenführ, S., Mendum, T. A., Hawkins, N. D., Ward, J. L., Beale, M. H., Wiechert, W., & McFadden, J. (2013). 13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis. Chemistry & Biology, 20(8), 1012–1021. https://doi.org/10.1016/j.chembiol.2013.06.012
Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice
Vaccine / Dec 01, 2001
da Cruz, F. W., McBride, A. J. A., Conceição, F. R., Dale, J. W., McFadden, J., & Dellagostin, O. A. (2001). Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice. Vaccine, 20(5–6), 731–736. https://doi.org/10.1016/s0264-410x(01)00414-5
Marina Baretti
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
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Other Research Interests (19)
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Most Relevant Publications (1+)
57 total publications
Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
Cancer Biology & Therapy / Apr 13, 2018
Baretti, M., Personeni, N., Destro, A., Santoro, A., & Rimassa, L. (2018). Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity? Cancer Biology & Therapy, 19(8), 659–663. https://doi.org/10.1080/15384047.2018.1450117