Work with thought leaders and academic experts in molecular medicine
Companies can greatly benefit from working with experts in the field of Molecular Medicine. These researchers possess in-depth knowledge and skills that can contribute to various aspects of a company's operations. They can provide valuable insights and expertise in areas such as drug discovery and development, personalized medicine, genomics, biomarker identification, and therapeutic interventions. By collaborating with Molecular Medicine experts, companies can accelerate their research and development processes, improve the effectiveness of their products and services, and stay at the forefront of scientific advancements. Additionally, these collaborations can lead to the identification of new business opportunities, partnerships, and potential commercialization of scientific discoveries.
Experts on NotedSource with backgrounds in molecular medicine include Dr. Sakshi Kabra Malpani, Regan Hamel, Aimee Eggler, Keisha Walters, Jeffrey Townsend, Giuliana Noratto, Nora S Vyas, Ph.D., Craig Hawker, Jennifer Aaker, Ping Luo, Marina Baretti, Samiul Amin, Katelyn Katelyn Masiuk, Kayvan Najarian, Maham Zain, Dr. Kevin Pawlak, Ph.D., Olivier Saulnier, Andrew Mikhail, Gianfranco Santovito, Ernesto Lowy, Niko Popitsch, and John Joe.
Regan Hamel
Senior bioinformatics scientist, specializing in single cell omics in the context of cellular reprogramming and neuroinflammation
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12 total publications
Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice
Molecular Therapy / Dec 01, 2020
Braga, A., Bandiera, S., Verheyen, J., Hamel, R., Rutigliani, C., Edenhofer, F., Smith, J. A., & Pluchino, S. (2020). Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Molecular Therapy, 28(12), 2677–2690. https://doi.org/10.1016/j.ymthe.2020.08.001
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
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Other Research Interests (26)
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Most Relevant Publications (3+)
25 total publications
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding
Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013
Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112
Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease
Journal of Medicinal Chemistry / Jan 03, 2013
Jacobs, J., Grum-Tokars, V., Zhou, Y., Turlington, M., Saldanha, S. A., Chase, P., Eggler, A., Dawson, E. S., Baez-Santos, Y. M., Tomar, S., Mielech, A. M., Baker, S. C., Lindsley, C. W., Hodder, P., Mesecar, A., & Stauffer, S. R. (2013). Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. Journal of Medicinal Chemistry, 56(2), 534–546. https://doi.org/10.1021/jm301580n
Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds
Molecules / Apr 03, 2000
Peterson, C., Tsao, R., Eggler, A., & Coats, J. (2000). Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds. Molecules, 5(12), 648–654. https://doi.org/10.3390/50400648
Keisha Walters
I am the Conoco-Dupont Professor of Chemical, Biological and Materials Engineering at the University of Oklahoma (OU), and I have experience in industry (R&D, Milliken Chemical).
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Other Research Interests (46)
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Most Relevant Publications (1+)
49 total publications
Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa
Journal of Nanobiotechnology / Mar 17, 2016
Vasquez, E. S., Feugang, J. M., Willard, S. T., Ryan, P. L., & Walters, K. B. (2016). Bioluminescent magnetic nanoparticles as potential imaging agents for mammalian spermatozoa. Journal of Nanobiotechnology, 14(1). https://doi.org/10.1186/s12951-016-0168-y
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
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Other Research Interests (78)
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Most Relevant Publications (6+)
207 total publications
The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity
The Journal of Molecular Diagnostics / Jan 01, 2022
Townsend, J. P., & Wells, C. R. (2022). The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity. The Journal of Molecular Diagnostics, 24(1), 101–103. https://doi.org/10.1016/j.jmoldx.2021.10.002
Cost-effectiveness of next-generation vaccines: The case of pertussis
Vaccine / Jun 01, 2016
Fitzpatrick, M. C., Wenzel, N. S., Scarpino, S. V., Althouse, B. M., Atkins, K. E., Galvani, A. P., & Townsend, J. P. (2016). Cost-effectiveness of next-generation vaccines: The case of pertussis. Vaccine, 34(29), 3405–3411. https://doi.org/10.1016/j.vaccine.2016.04.010
Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US
Vaccine / Jan 01, 2016
Alfaro-Murillo, J. A., Townsend, J. P., & Galvani, A. P. (2016). Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US. Vaccine, 34(2), 225–229. https://doi.org/10.1016/j.vaccine.2015.11.039
Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty
Vaccine / Jun 01, 2013
Ndeffo Mbah, M. L., Medlock, J., Meyers, L. A., Galvani, A. P., & Townsend, J. P. (2013). Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty. Vaccine, 31(30), 3079–3089. https://doi.org/10.1016/j.vaccine.2013.04.052
Monitoring and modeling horizontal gene transfer
Nature Biotechnology / Aug 31, 2004
Nielsen, K. M., & Townsend, J. P. (2004). Monitoring and modeling horizontal gene transfer. Nature Biotechnology, 22(9), 1110–1114. https://doi.org/10.1038/nbt1006
Monitoring horizontal gene transfer
Nature Biotechnology / Nov 01, 2004
Davison, J. (2004). Monitoring horizontal gene transfer. Nature Biotechnology, 22(11), 1349–1349. https://doi.org/10.1038/nbt1104-1349a
Giuliana Noratto
Food Scientist PhD and Registered Dietician - Texas A&M University
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Other Research Interests (48)
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Most Relevant Publications (2+)
91 total publications
Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion
Molecules / Oct 25, 2022
Silveira Rabelo, A. C., Mertens-Talcott, S. U., Chew, B. P., & Noratto, G. (2022). Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion. Molecules, 27(21), 7245. https://doi.org/10.3390/molecules27217245
Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry / Nov 01, 2022
Rabelo, A. C. S., Miglino, M. A., Arbizu, S., Carreira, A. C. O., Filho, A. J. C., Carneiro, F. J. C., Layosa, M. A. A., & Noratto, G. (2022). Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry, 22(18), 3136–3147. https://doi.org/10.2174/1871520622666220608122154
Nora S Vyas, Ph.D.
Associate Professor of Mental Health, with interest in civic engagement and partnerships
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30 total publications
Recent Developments in Neurochemical Imaging in Schizophrenia: An Update
Current Medicinal Chemistry / Jan 01, 2013
S. Vyas, N., H. Patel, N., Herscovitch, P., K. Puri, B., & Lanzenberger, R. (2013). Recent Developments in Neurochemical Imaging in Schizophrenia: An Update. Current Medicinal Chemistry, 20(3), 351–356. https://doi.org/10.2174/092986713804870765
Craig Hawker
Professor at University of California, Santa Barbara
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100 total publications
A new convergent approach to monodisperse dendritic macromolecules
J. Chem. Soc., Chem. Commun. / Jan 01, 1990
Hawker, C., & Fréchet, J. M. J. (1990). A new convergent approach to monodisperse dendritic macromolecules. J. Chem. Soc., Chem. Commun., 15, 1010–1013. https://doi.org/10.1039/c39900001010
Jennifer Aaker
General Atlantic Professor, Stanford University
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Other Research Interests (38)
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79 total publications
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG
Advances in Enzyme Regulation / Jan 01, 2002
SPECIAL SYMPOSIUM LECTURE: SIR HANS L. KORNBERG. (2002). Advances in Enzyme Regulation, 42, EX17. https://doi.org/10.1016/s0065-2571(01)00055-3
Ping Luo
Postdoctoral Researcher at Princess Margaret Cancer Centre with experience in deep learning
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Other Research Interests (26)
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Most Relevant Publications (2+)
23 total publications
deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks
Frontiers in Genetics / Jan 29, 2019
Luo, P., Ding, Y., Lei, X., & Wu, F.-X. (2019). deepDriver: Predicting Cancer Driver Genes Based on Somatic Mutations Using Deep Convolutional Neural Networks. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00013
Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning
Frontiers in Genetics / Apr 02, 2019
Luo, P., Xiao, Q., Wei, P.-J., Liao, B., & Wu, F.-X. (2019). Identifying Disease-Gene Associations With Graph-Regularized Manifold Learning. Frontiers in Genetics, 10. https://doi.org/10.3389/fgene.2019.00270
Marina Baretti
I am a clinical translational researcher in gastrointestinal (GI) oncology, collaborating closely with laboratory-based researchers to move laboratory findings into patients and to answer important clinical questions.
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Other Research Interests (19)
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57 total publications
Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
Cancer Biology & Therapy / Apr 13, 2018
Baretti, M., Personeni, N., Destro, A., Santoro, A., & Rimassa, L. (2018). Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity? Cancer Biology & Therapy, 19(8), 659–663. https://doi.org/10.1080/15384047.2018.1450117
Samiul Amin
Professor of Practice at University of Miami Professor of Practice and Director ECAP at University of Miami with expertise in Formulation Design, Rheology, Biosurfactants, Biopolymers and Materials Science.
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Other Research Interests (59)
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68 total publications
Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins
Molecules / Dec 12, 2014
Lewis, E., Qi, W., Kidder, L., Amin, S., Kenyon, S., & Blake, S. (2014). Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins. Molecules, 19(12), 20888–20905. https://doi.org/10.3390/molecules191220888
Investigating the Influence of Polysorbate 20/80 and Polaxomer P188 on the Surface & Interfacial Properties of Bovine Serum Albumin and Lysozyme
Pharmaceutical Research / May 20, 2019
Begum, F., & Amin, S. (2019). Investigating the Influence of Polysorbate 20/80 and Polaxomer P188 on the Surface & Interfacial Properties of Bovine Serum Albumin and Lysozyme. Pharmaceutical Research, 36(7). https://doi.org/10.1007/s11095-019-2631-6
Katelyn Katelyn Masiuk
Co-Founder and CSO at Immunovec
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13 total publications
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates
Molecular Therapy / Aug 01, 2019
Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome
Cell Stem Cell / Feb 01, 2019
Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003
PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector
Molecular Therapy - Methods & Clinical Development / Jun 01, 2019
Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods & Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005
Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells
Molecular Therapy / Sep 01, 2017
Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023
Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy
Stem Cells / Apr 23, 2015
Baldwin, K., Urbinati, F., Romero, Z., Campo-Fernandez, B., Kaufman, M. L., Cooper, A. R., Masiuk, K., Hollis, R. P., & Kohn, D. B. (2015). Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy. Stem Cells, 33(5), 1532–1542. https://doi.org/10.1002/stem.1957
Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study
Human Gene Therapy / Oct 01, 2018
Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061
Kayvan Najarian
Professor of Comp Med and Bioinf, Emergency Med, and Electrical and Comp Engineering
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Other Research Interests (40)
Most Relevant Publications (1+)
108 total publications
Deep learning in pharmacogenomics: from gene regulation to patient stratification
Pharmacogenomics / May 01, 2018
Kalinin, A. A., Higgins, G. A., Reamaroon, N., Soroushmehr, S., Allyn-Feuer, A., Dinov, I. D., Najarian, K., & Athey, B. D. (2018). Deep learning in pharmacogenomics: from gene regulation to patient stratification. Pharmacogenomics, 19(7), 629–650. https://doi.org/10.2217/pgs-2018-0008
Maham Zain
PhD Student at University of Toronto
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7 total publications
Differential modulation of thermal preference after sensitization by optogenetic or pharmacological activation of heat-sensitive nociceptors
Molecular Pain / Jan 01, 2021
Li, J., Zain, M., & Bonin, R. P. (2021). Differential modulation of thermal preference after sensitization by optogenetic or pharmacological activation of heat-sensitive nociceptors. Molecular Pain, 17, 174480692110009. https://doi.org/10.1177/17448069211000910
Dr. Kevin Pawlak, Ph.D.
Xavier University School of Medicine
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Other Research Interests (14)
Most Relevant Publications (5+)
12 total publications
The role of progesterone metabolites in breast cancer: Potential for new diagnostics and therapeutics
The Journal of Steroid Biochemistry and Molecular Biology / Feb 01, 2005
Wiebe, J. P., Lewis, M. J., Cialacu, V., Pawlak, K. J., & Zhang, G. (2005). The role of progesterone metabolites in breast cancer: Potential for new diagnostics and therapeutics. The Journal of Steroid Biochemistry and Molecular Biology, 93(2–5), 201–208. https://doi.org/10.1016/j.jsbmb.2004.12.003
Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites
The Journal of Steroid Biochemistry and Molecular Biology / Nov 01, 2007
Pawlak, K. J., & Wiebe, J. P. (2007). Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites. The Journal of Steroid Biochemistry and Molecular Biology, 107(3–5), 172–179. https://doi.org/10.1016/j.jsbmb.2007.05.030
Membrane 5α-pregnane-3,20-dione (5αP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5αP and down-regulated by the progesterone metabolites, 3α-dihydroprogesterone and 20α-dihydroprogesterone, with associated changes in cell proliferation and detachment
The Journal of Steroid Biochemistry and Molecular Biology / Nov 01, 2005
Pawlak, K. J., Zhang, G., & Wiebe, J. P. (2005). Membrane 5α-pregnane-3,20-dione (5αP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5αP and down-regulated by the progesterone metabolites, 3α-dihydroprogesterone and 20α-dihydroprogesterone, with associated changes in cell proliferation and detachment. The Journal of Steroid Biochemistry and Molecular Biology, 97(3), 278–288. https://doi.org/10.1016/j.jsbmb.2005.05.014
Mechanism of action of the breast cancer-promoter hormone, 5α-dihydroprogesterone (5αP), involves plasma membrane-associated receptors and MAPK activation
The Journal of Steroid Biochemistry and Molecular Biology / Jan 01, 2016
Wiebe, J. P., Pawlak, K. J., & Kwok, A. (2016). Mechanism of action of the breast cancer-promoter hormone, 5α-dihydroprogesterone (5αP), involves plasma membrane-associated receptors and MAPK activation. The Journal of Steroid Biochemistry and Molecular Biology, 155, 166–176. https://doi.org/10.1016/j.jsbmb.2015.10.021
Decreased CytochromecOxidase IV Expression Reduces Steroidogenesis
Journal of Pharmacology and Experimental Therapeutics / May 10, 2011
Pawlak, K. J., Prasad, M., McKenzie, K. A., Wiebe, J. P., Gairola, C. G., Whittal, R. M., & Bose, H. S. (2011). Decreased CytochromecOxidase IV Expression Reduces Steroidogenesis. Journal of Pharmacology and Experimental Therapeutics, 338(2), 598–604. https://doi.org/10.1124/jpet.111.182634
Olivier Saulnier
The Hospital for Sick Children
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Other Research Interests (17)
Most Relevant Publications (1+)
25 total publications
The LIN28B –let‐7–PBK
pathway is essential for group 3
medulloblastoma tumor growth and
survival
Molecular Oncology / Aug 07, 2023
Shahab, S. W., Roggeveen, C. M., Sun, J., Kunhiraman, H., McSwain, L. F., Juraschka, K., Kumar, S. A., Saulnier, O., Taylor, M. D., Schniederjan, M., Schnepp, R. W., MacDonald, T. J., & Kenney, A. M. (2023). The <scp>LIN28B</scp>–let‐7–<scp>PBK</scp> pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology. Portico. https://doi.org/10.1002/1878-0261.13477
Andrew Mikhail
Department of Kinesiology, McMaster University
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Other Research Interests (20)
Most Relevant Publications (1+)
14 total publications
AMPK is mitochondrial medicine for neuromuscular disorders
Trends in Molecular Medicine / Jul 01, 2023
Mikhail, A. I., Ng, S. Y., Mattina, S. R., & Ljubicic, V. (2023). AMPK is mitochondrial medicine for neuromuscular disorders. Trends in Molecular Medicine, 29(7), 512–529. https://doi.org/10.1016/j.molmed.2023.03.008
Ernesto Lowy
Senior Bioinformatician specialised in Cancer Genomics
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Other Research Interests (28)
Most Relevant Publications (2+)
67 total publications
Phylogeography of crossbills, bullfinches, grosbeaks, and rosefinches
Cellular and Molecular Life Sciences / Jul 01, 2001
Arnaiz-Villena, A., Guillén, J., Ruiz-del-Valle, V., Lowy, E., Zamora, J., Varela, P., Stefani, D., & Allende, L. M. (2001). Phylogeography of crossbills, bullfinches, grosbeaks, and rosefinches. Cellular and Molecular Life Sciences, 58(8), 1159–1166. https://doi.org/10.1007/pl00000930
Both morphological and molecular characters support speciation of South American siskins by sexual selection
Cellular and Molecular Life Sciences / Dec 01, 2001
van den Elzen, R., Guillén, J., Ruiz-del-Valle, V., Allende, L. M., Lowy, E., Zamora, J., & Arnaiz-Villena, A. (2001). Both morphological and molecular characters support speciation of South American siskins by sexual selection. Cellular and Molecular Life Sciences, 58(14), 2117–2128. https://doi.org/10.1007/pl00000841
John Joe
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
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Other Research Interests (73)
Most Relevant Publications (2+)
95 total publications
13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis
Chemistry & Biology / Aug 01, 2013
Beste, D. J. V., Nöh, K., Niedenführ, S., Mendum, T. A., Hawkins, N. D., Ward, J. L., Beale, M. H., Wiechert, W., & McFadden, J. (2013). 13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis. Chemistry & Biology, 20(8), 1012–1021. https://doi.org/10.1016/j.chembiol.2013.06.012
Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice
Vaccine / Dec 01, 2001
da Cruz, F. W., McBride, A. J. A., Conceição, F. R., Dale, J. W., McFadden, J., & Dellagostin, O. A. (2001). Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice. Vaccine, 20(5–6), 731–736. https://doi.org/10.1016/s0264-410x(01)00414-5
Example molecular medicine projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on molecular medicine?
Drug Discovery and Development
A pharmaceutical company can collaborate with a Molecular Medicine expert to identify potential drug targets, design and optimize drug candidates, and conduct preclinical and clinical trials. This collaboration can significantly speed up the drug discovery and development process, leading to the creation of novel and effective therapies.
Personalized Medicine
By working with a Molecular Medicine researcher, a healthcare company can develop personalized treatment strategies based on an individual's genetic makeup, lifestyle, and environmental factors. This approach can improve patient outcomes, minimize adverse effects, and optimize healthcare resources.
Genomics and Precision Medicine
Companies in the biotechnology and diagnostics sectors can collaborate with Molecular Medicine experts to leverage genomic data for disease diagnosis, prognosis, and treatment selection. This collaboration can lead to the development of innovative diagnostic tools, targeted therapies, and precision medicine approaches.
Biomarker Identification
A company focused on biomarker discovery can benefit from collaborating with a Molecular Medicine expert. These researchers can identify and validate biomarkers that can be used for early disease detection, monitoring treatment response, and predicting patient outcomes. Such collaborations can drive the development of diagnostic tests and personalized medicine solutions.
Therapeutic Interventions
Pharmaceutical and biotechnology companies can partner with Molecular Medicine experts to explore novel therapeutic interventions, including gene therapies, RNA-based therapeutics, and targeted drug delivery systems. These collaborations can lead to the development of breakthrough treatments for various diseases and conditions.