Work with academic experts in molecular medicine

A scholar or researcher with expertise in molecular medicine can help business and industrial clients solve their molecular medicine problems and conduct molecular medicine research to get ahead on R&D. Experts on NotedSource with backgrounds in molecular medicine include Aimee Eggler, Giuliana Noratto, Keisha Walters, Jeffrey Townsend, Dr. Sakshi Kabra Malpani, Jennifer Aaker, Katelyn Katelyn Masiuk, John Joe, and Marina Baretti.

Aimee Eggler

Professor of Chemistry and Biochemistry at Villanova University
Villanova, Pennsylvania, United States of America
Most Relevant Research Interests
Molecular Medicine
Other Research Interests (26)
Biochemistry
Biochemistry education
Cell culture
Oxidative stress
Natural products
And 21 more
About
Most Relevant Publications (3+)

25 total publications

Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding

Bioorganic & Medicinal Chemistry Letters / Nov 01, 2013

Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J. S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y. M., Lindsley, C. W., Hodder, P., Mesecar, A. D., & Stauffer, S. R. (2013). Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters, 23(22), 6172–6177. https://doi.org/10.1016/j.bmcl.2013.08.112

Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease

Journal of Medicinal Chemistry / Jan 03, 2013

Jacobs, J., Grum-Tokars, V., Zhou, Y., Turlington, M., Saldanha, S. A., Chase, P., Eggler, A., Dawson, E. S., Baez-Santos, Y. M., Tomar, S., Mielech, A. M., Baker, S. C., Lindsley, C. W., Hodder, P., Mesecar, A., & Stauffer, S. R. (2013). Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease. Journal of Medicinal Chemistry, 56(2), 534–546. https://doi.org/10.1021/jm301580n

Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds

Molecules / Apr 03, 2000

Peterson, C., Tsao, R., Eggler, A., & Coats, J. (2000). Insecticidal Activity of Cyanohydrin and Monoterpenoid Compounds. Molecules, 5(12), 648–654. https://doi.org/10.3390/50400648

Giuliana Noratto

Food Scientist PhD and Registered Dietician - Texas A&M University
Most Relevant Research Interests
Molecular Medicine
Molecular Medicine
Other Research Interests (48)
Food Science
human nutrition
disease prevention and treatment
Nutrition
Human Health
And 43 more
About
Most Relevant Publications (2+)

91 total publications

Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion

Molecules / Oct 25, 2022

Silveira Rabelo, A. C., Mertens-Talcott, S. U., Chew, B. P., & Noratto, G. (2022). Dark Sweet Cherry (Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion. Molecules, 27(21), 7245. https://doi.org/10.3390/molecules27217245

Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells

Anti-Cancer Agents in Medicinal Chemistry / Nov 01, 2022

Rabelo, A. C. S., Miglino, M. A., Arbizu, S., Carreira, A. C. O., Filho, A. J. C., Carneiro, F. J. C., Layosa, M. A. A., & Noratto, G. (2022). Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry, 22(18), 3136–3147. https://doi.org/10.2174/1871520622666220608122154

Jeffrey Townsend

Professor of Biostatistics and Ecology & Evolutionary Biology
New Haven, CT
Most Relevant Research Interests
Molecular Medicine
Other Research Interests (78)
Statistics
cancer genetics
disease modeling
antibiotic resistance
Evolutionary Genomics
And 73 more
About
Most Relevant Publications (6+)

207 total publications

The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity

The Journal of Molecular Diagnostics / Jan 01, 2022

Townsend, J. P., & Wells, C. R. (2022). The Prognostic Value of an RT-PCR Test for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Is Contingent on Timing across Disease Time Course in addition to Assay Sensitivity. The Journal of Molecular Diagnostics, 24(1), 101–103. https://doi.org/10.1016/j.jmoldx.2021.10.002

Cost-effectiveness of next-generation vaccines: The case of pertussis

Vaccine / Jun 01, 2016

Fitzpatrick, M. C., Wenzel, N. S., Scarpino, S. V., Althouse, B. M., Atkins, K. E., Galvani, A. P., & Townsend, J. P. (2016). Cost-effectiveness of next-generation vaccines: The case of pertussis. Vaccine, 34(29), 3405–3411. https://doi.org/10.1016/j.vaccine.2016.04.010

Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US

Vaccine / Jan 01, 2016

Alfaro-Murillo, J. A., Townsend, J. P., & Galvani, A. P. (2016). Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US. Vaccine, 34(2), 225–229. https://doi.org/10.1016/j.vaccine.2015.11.039

Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty

Vaccine / Jun 01, 2013

Ndeffo Mbah, M. L., Medlock, J., Meyers, L. A., Galvani, A. P., & Townsend, J. P. (2013). Optimal targeting of seasonal influenza vaccination toward younger ages is robust to parameter uncertainty. Vaccine, 31(30), 3079–3089. https://doi.org/10.1016/j.vaccine.2013.04.052

Monitoring and modeling horizontal gene transfer

Nature Biotechnology / Aug 31, 2004

Nielsen, K. M., & Townsend, J. P. (2004). Monitoring and modeling horizontal gene transfer. Nature Biotechnology, 22(9), 1110–1114. https://doi.org/10.1038/nbt1006

Monitoring horizontal gene transfer

Nature Biotechnology / Nov 01, 2004

Davison, J. (2004). Monitoring horizontal gene transfer. Nature Biotechnology, 22(11), 1349–1349. https://doi.org/10.1038/nbt1104-1349a

Katelyn Katelyn Masiuk

Co-Founder and CSO at Immunovec
Most Relevant Research Interests
Molecular Medicine
Molecular Medicine
Molecular Medicine
Molecular Medicine
Other Research Interests (23)
Cell Biology
Genetics
Genetics
Molecular Biology
Drug Discovery
And 18 more
About
Most Relevant Publications (6+)

13 total publications

Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates

Molecular Therapy / Aug 01, 2019

Romero, Z., Lomova, A., Said, S., Miggelbrink, A., Kuo, C. Y., Campo-Fernandez, B., Hoban, M. D., Masiuk, K. E., Clark, D. N., Long, J., Sanchez, J. M., Velez, M., Miyahira, E., Zhang, R., Brown, D., Wang, X., Kurmangaliyev, Y. Z., Hollis, R. P., & Kohn, D. B. (2019). Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. Molecular Therapy, 27(8), 1389–1406. https://doi.org/10.1016/j.ymthe.2019.05.014

Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome

Cell Stem Cell / Feb 01, 2019

Masiuk, K. E., Laborada, J., Roncarolo, M. G., Hollis, R. P., & Kohn, D. B. (2019). Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome. Cell Stem Cell, 24(2), 309-317.e7. https://doi.org/10.1016/j.stem.2018.12.003

PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector

Molecular Therapy - Methods & Clinical Development / Jun 01, 2019

Masiuk, K. E., Zhang, R., Osborne, K., Hollis, R. P., Campo-Fernandez, B., & Kohn, D. B. (2019). PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector. Molecular Therapy - Methods & Clinical Development, 13, 390–398. https://doi.org/10.1016/j.omtm.2019.03.005

Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells

Molecular Therapy / Sep 01, 2017

Masiuk, K. E., Brown, D., Laborada, J., Hollis, R. P., Urbinati, F., & Kohn, D. B. (2017). Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells. Molecular Therapy, 25(9), 2163–2175. https://doi.org/10.1016/j.ymthe.2017.05.023

Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy

Stem Cells / Apr 23, 2015

Baldwin, K., Urbinati, F., Romero, Z., Campo-Fernandez, B., Kaufman, M. L., Cooper, A. R., Masiuk, K., Hollis, R. P., & Kohn, D. B. (2015). Enrichment of Human Hematopoietic Stem/Progenitor Cells Facilitates Transduction for Stem Cell Gene Therapy. Stem Cells, 33(5), 1532–1542. https://doi.org/10.1002/stem.1957

Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study

Human Gene Therapy / Oct 01, 2018

Urbinati, F., Campo Fernandez, B., Masiuk, K. E., Poletti, V., Hollis, R. P., Koziol, C., Kaufman, M. L., Brown, D., Mavilio, F., & Kohn, D. B. (2018). Gene Therapy for Sickle Cell Disease:A Lentiviral Vector Comparison Study. Human Gene Therapy, 29(10), 1153–1166. https://doi.org/10.1089/hum.2018.061

John Joe

Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Most Relevant Research Interests
Molecular Medicine
Other Research Interests (73)
microbiology
systems biology
genetics
quantum biology
Genetics
And 68 more
Most Relevant Publications (2+)

95 total publications

13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

Chemistry & Biology / Aug 01, 2013

Beste, D. J. V., Nöh, K., Niedenführ, S., Mendum, T. A., Hawkins, N. D., Ward, J. L., Beale, M. H., Wiechert, W., & McFadden, J. (2013). 13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis. Chemistry & Biology, 20(8), 1012–1021. https://doi.org/10.1016/j.chembiol.2013.06.012

Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice

Vaccine / Dec 01, 2001

da Cruz, F. W., McBride, A. J. A., Conceição, F. R., Dale, J. W., McFadden, J., & Dellagostin, O. A. (2001). Expression of the B-cell and T-cell epitopes of the rabies virus nucleoprotein in Mycobacterium bovis BCG and induction of an humoral response in mice. Vaccine, 20(5–6), 731–736. https://doi.org/10.1016/s0264-410x(01)00414-5