Work with thought leaders and academic experts in biophysics
Companies can greatly benefit from working with experts in the field of Biophysics. These researchers bring a unique set of skills and knowledge that can contribute to various aspects of a company's operations. They can provide valuable insights and solutions in areas such as drug discovery, medical device development, bioinformatics, biotechnology, and more. By collaborating with Biophysics experts, companies can enhance their research capabilities, accelerate innovation, improve product development, and gain a competitive edge in the market.
Researchers on NotedSource with backgrounds in biophysics include Aimee Eggler, Ping Luo, Michael W Harman, Ajay Badhan, Martin Tsui, Dr. Shilpa Patil, Ph.D, and Jeffrey Townsend.
Aimee Eggler
Professor of Chemistry and Biochemistry at Villanova University
Most Relevant Research Interests
Other Research Interests (18)
About
Most Relevant Publications (3+)
25 total publications
Screening for natural chemoprevention agents that modify human Keap1
Analytical Biochemistry / Feb 01, 2012
Hu, C., Nikolic, D., Eggler, A. L., Mesecar, A. D., & van Breemen, R. B. (2012). Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry, 421(1), 108–114. https://doi.org/10.1016/j.ab.2011.10.028
Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1
Biochemical and Biophysical Research Communications / Oct 01, 2010
Small, E., Eggler, A., & Mesecar, A. D. (2010). Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3–RINGBox1 protein complex and elucidation of its quaternary structure with Keap1. Biochemical and Biophysical Research Communications, 400(4), 471–475. https://doi.org/10.1016/j.bbrc.2010.08.062
The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides
Archives of Biochemistry and Biophysics / Nov 01, 2008
McAdams, K., Casper, E. S., Matthew Haas, R., Santarsiero, B. D., Eggler, A. L., Mesecar, A., & Halkides, C. J. (2008). The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides. Archives of Biochemistry and Biophysics, 479(2), 105–113. https://doi.org/10.1016/j.abb.2008.08.019
See Full Profile
Ping Luo
Bioinformatics Specialist at Princess Margaret Cancer Centre with experience in deep learning
Most Relevant Research Interests
Other Research Interests (21)
About
Most Relevant Publications (1+)
23 total publications
Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets
Computational and Structural Biotechnology Journal / Jan 01, 2022
Mahalanabis, A., Turinsky, A. L., Husić, M., Christensen, E., Luo, P., Naidas, A., Brudno, M., Pugh, T., Ramani, A. K., & Shooshtari, P. (2022). Evaluation of single-cell RNA-seq clustering algorithms on cancer tumor datasets. Computational and Structural Biotechnology Journal, 20, 6375–6387. https://doi.org/10.1016/j.csbj.2022.10.029
See Full Profile
Michael W Harman
Distinguished Subject Matter Expert & Leader in Medical Technologies.
Most Relevant Research Interests
Other Research Interests (13)
About
Most Relevant Publications (4+)
15 total publications
Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag
Biophysical Journal / Nov 01, 2013
Harman, M., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). Viscous Dynamics of Lyme Disease and Syphilis Spirochetes Reveal Flagellar Torque and Drag. Biophysical Journal, 105(10), 2273–2280. https://doi.org/10.1016/j.bpj.2013.10.004
Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium
Biophysical Journal / Feb 01, 2017
Harman, M. W., Hamby, A. E., Boltyanskiy, R., Belperron, A. A., Bockenstedt, L. K., Kress, H., Dufresne, E. R., & Wolgemuth, C. W. (2017). Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium. Biophysical Journal, 112(4), 746–754. https://doi.org/10.1016/j.bpj.2016.12.039
Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels
Biophysical Journal / Feb 01, 2018
Harman, M. W., Franck, C., & Reichner, J. (2018). Four Dimensional Traction Measurements of Chemotactic Neutrophils in Hydrogels. Biophysical Journal, 114(3), 324a. https://doi.org/10.1016/j.bpj.2017.11.1819
The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments
Biophysical Journal / Jan 01, 2013
Harman, M. W., Vig, D. K., Radolf, J. D., & Wolgemuth, C. W. (2013). The Computational Analysis of Spirochete Motility in Viscous Fluids: Mimicking Host Reservoir Micro-Environments. Biophysical Journal, 104(2), 638a–639a. https://doi.org/10.1016/j.bpj.2012.11.3526
See Full Profile
Ajay Badhan
Research Biologist, Lethbridge Research Center, Canada
Most Relevant Research Interests
Other Research Interests (26)
About
Most Relevant Publications (1+)
29 total publications
Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses
Computational and Structural Biotechnology Journal / Jan 01, 2022
Badhan, A., Low, K. E., Jones, D. R., Xing, X., Milani, M. R. M., Polo, R. O., Klassen, L., Venketachalam, S., Hahn, M. G., Abbott, D. W., & McAllister, T. A. (2022). Mechanistic insights into the digestion of complex dietary fibre by the rumen microbiota using combinatorial high-resolution glycomics and transcriptomic analyses. Computational and Structural Biotechnology Journal, 20, 148–164. https://doi.org/10.1016/j.csbj.2021.12.009
See Full Profile
Martin Tsui
University of California, San Francisco
Most Relevant Research Interests
Other Research Interests (15)
About
Most Relevant Publications (3+)
17 total publications
Structure Principles of CRISPR-Cas Surveillance and Effector Complexes
Annual Review of Biophysics / Jun 22, 2015
Tsui, T. K. M., & Li, H. (2015). Structure Principles of CRISPR-Cas Surveillance and Effector Complexes. Annual Review of Biophysics, 44(1), 229–255. https://doi.org/10.1146/annurev-biophys-060414-033939
The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9
Biophysical Journal / Feb 01, 2017
Kin Martin Tsui, T., Hand, T. H., & Li, H. (2017). The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9. Biophysical Journal, 112(3), 71a. https://doi.org/10.1016/j.bpj.2016.11.431
The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9
Biophysical Journal / Feb 01, 2017
Kin Martin Tsui, T., Hand, T. H., & Li, H. (2017). The Impact of DNA Topology on Target Selection by a Cytosine-Specific Cas9. Biophysical Journal, 112(3), 71a. https://doi.org/10.1016/j.bpj.2016.11.431
See Full Profile
Dr. Shilpa Patil, Ph.D
PhD & Postdoc level expertise in Cancer Research
Most Relevant Research Interests
Other Research Interests (11)
About
Most Relevant Publications (1+)
20 total publications
Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation
Biochimica et Biophysica Acta (BBA) - General Subjects / Aug 01, 2018
Kaypee, S., Sahadevan, S. A., Sudarshan, D., Halder Sinha, S., Patil, S., Senapati, P., Kodaganur, G. S., Mohiyuddin, A., Dasgupta, D., & Kundu, T. K. (2018). Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(8), 1729–1741. https://doi.org/10.1016/j.bbagen.2018.05.003
See Full Profile
Jeffrey Townsend
Professor of Biostatistics and Ecology & Evolutionary Biology
Most Relevant Research Interests
Other Research Interests (52)
About
Most Relevant Publications (3+)
207 total publications
The somatic molecular evolution of cancer: Mutation, selection, and epistasis
Progress in Biophysics and Molecular Biology / Oct 01, 2021
Dasari, K., Somarelli, J. A., Kumar, S., & Townsend, J. P. (2021). The somatic molecular evolution of cancer: Mutation, selection, and epistasis. Progress in Biophysics and Molecular Biology, 165, 56–65. https://doi.org/10.1016/j.pbiomolbio.2021.08.003
Epidemiological mechanisms of genetic resistance to kuru
Journal of The Royal Society Interface / Aug 06, 2013
Atkins, K. E., Townsend, J. P., Medlock, J., & Galvani, A. P. (2013). Epidemiological mechanisms of genetic resistance to kuru. Journal of The Royal Society Interface, 10(85), 20130331. https://doi.org/10.1098/rsif.2013.0331
The influence of altruism on influenza vaccination decisions
Journal of The Royal Society Interface / Apr 11, 2012
Shim, E., Chapman, G. B., Townsend, J. P., & Galvani, A. P. (2012). The influence of altruism on influenza vaccination decisions. Journal of The Royal Society Interface, 9(74), 2234–2243. https://doi.org/10.1098/rsif.2012.0115
See Full Profile
Example biophysics projects
How can companies collaborate more effectively with researchers, experts, and thought leaders to make progress on biophysics?
Drug Discovery
A Biophysics expert can contribute to the development of new drugs by studying the interactions between molecules and biological systems. They can provide insights into the structure and function of proteins, identify potential drug targets, and optimize drug candidates for efficacy and safety.
Medical Device Development
Biophysics researchers can play a crucial role in the development of medical devices. They can apply their knowledge of biophysical principles to design and optimize devices such as biosensors, imaging systems, and prosthetics. Their expertise can ensure the accuracy, sensitivity, and reliability of these devices.
Bioinformatics
Biophysics experts can contribute to the field of bioinformatics by analyzing and interpreting large-scale biological data. They can develop computational models and algorithms to study complex biological systems, predict protein structures, and analyze genomic data. Their expertise can help companies extract valuable insights from big data and make informed decisions.
Biotechnology
Biophysics researchers can contribute to the advancement of biotechnology by applying their knowledge of physical and chemical principles to manipulate biological systems. They can develop innovative techniques for gene editing, protein engineering, and biomaterial synthesis. Their expertise can drive breakthroughs in areas such as personalized medicine, agriculture, and renewable energy.
Biophysical Characterization
Companies can benefit from collaborating with Biophysics experts for the characterization of biomolecules and biological systems. They can use techniques such as spectroscopy, microscopy, and mass spectrometry to study the structure, dynamics, and interactions of biomolecules. This information is crucial for understanding disease mechanisms, optimizing drug formulations, and improving the performance of biotechnological processes.